Search the Studies

70 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number Title Protocol Status Min-Max Age Institute Keywords
000310-CHA Phase 1/2, First-in-Human, Open-Label, Dose-Escalation Study of the Safety and Efficacy of Gene Therapy for Congenital Adrenal Hyperplasia through Administration of an Adeno-Associated Virus (AAV) Serotype 5-Based Recombinant Vector Encoding the Human Recruitment has not started18-125 YearsNICHDCongenital Night
16-EI-0024Rod and Cone Mediated Function in Retinal DiseaseParticipants currently recruited/enrolled5-125 YearsNEI Night Blindness
16-CH-0164A Phase III Extension Study of Efficacy, Safety and Tolerability of Chronocort (Registered) in the Treatment of Congenital Adrenal HyperplasiaCompleted Study; data analyses ongoing18-80 YearsNICHDCongenital Night
001085-DPhase 2 Study of the PTH-Independent Effects of Encaleret on Mineral Homeostasis in Subjects with Post-Surgical Hypoparathyroidism (PSH)Recruitment has not started18-125 YearsNIDCRNight
000923-HObservational Study of Cardiac Arrhythmias in Subjects Treated with BTK InhibitorsParticipants currently recruited/enrolled18-110 YearsNHLBIStationary
000911-DKDinner Time for Obesity and Prediabetes (DTOP)Recruitment has not started18-50 YearsNIDDKNight
000906-IA Phase 2 Randomized, Double-Blinded Cross-Over Design Study of the Early Metabolic Effects of Dolutegravir or Tenofovir Alefenamide in Healthy VolunteersRecruitment has not started18-55 YearsNIAIDNight
000780-DA Phase 2 Study of Denosumab for Prevention of Skeletal Disease Progression in Children with Fibrous DysplasiaParticipants currently recruited/enrolled4-14 YearsNIDCRNight
000756-DKPhase II Study of Growth Hormone Inhibition Using Pegvisomant In Severe Insulin ResistanceParticipants currently recruited/enrolled18-65 YearsNIDDKNight
000754-MNIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar DisorderParticipants currently recruited/enrolled12-70 YearsNIMH Stationary
000740-CHA Phase 3 Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Chronocort in the Treatment of Participants Aged 16 Years and Over with Congenital Adrenal HyperplasiaEnrolling by Invitation18-125 YearsNICHDCongenital
000617-DKA Natural History Study of Metabolic Sizing in Health and DiseaseParticipants currently recruited/enrolled10-125 YearsNIDDKNight
000494-DKNatural History of Fontan Associated Liver Disease and the Evaluation of Biomarkers for Disease Severity AssessmentParticipants currently recruited/enrolled18-125 YearsNIDDKCongenital
000423-CFeasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults with Sickle Cell Disease (SCD): A Pilot Randomized Controlled TrialParticipants currently recruited/enrolled18-55 YearsNCI Night
000414-CHPilot Study of an Optic-to-Audio Device in a Pediatric Cohort with CLN3-related Conditions or Low VisionParticipants currently recruited/enrolled6-18 YearsNICHDBlindness
000411-CCA Feasibility Pilot Study of a Virtual Education-Based Transition Intervention to Improve Transition Readiness in Adolescent and Young Adults with Congenital Adrenal Hyperplasia.Recruitment has not started16-22 YearsCC Congenital
000350-DUse of Clear Aligners for the Treatment of Dental Malocclusion In Individuals with Osteogenesis Imperfecta Types III and IVParticipants currently recruited/enrolled12-40 YearsNIDCRNight
000297-CHA Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Crinecerfont (NBI-74788) in Adult Subjects with Classic Congenital Adrenal Hyperplasia, Followed by Open-Label TreatmentParticipants currently recruited/enrolled18-125 YearsNICHDCongenital
000236-IA Phase 1 Study of Empagliflozin as Treatment for Severe Congenital Neutropenia Due to G6PC3 DeficiencyParticipants currently recruited/enrolled18-125 YearsNIAIDCongenital
000224-CHDevelopment of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep ApneaParticipants currently recruited/enrolled3-12 YearsNICHDNight
000051-NNIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)Participants currently recruited/enrolled48-70 YearsNINDSNight
22-DK-0002Effect of Ultra-processed versus Unprocessed Diets on Energy MetabolismParticipants currently recruited/enrolled18-60 YearsNIDDKStationary
20-D-0122A Phase IIb, Open-label Dose-ranging Study Evaluating the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics, and Efficacy of CLTX-305 (encaleret) in Autosomal Dominant Hypocalcemia Type 1 (ADH1)No longer recruiting/follow-up only16-125 YearsNIDCRNight
20-CH-0126Data Collection Study of Pediatric and Adolescent Gynecology ConditionsParticipants currently recruited/enrolled0-125 YearsNICHDCongenital
20-CC-0113Cardiopulmonary Inflammation and Multi-System Imaging During the Clinical Course of COVID-19 Infection in Asymptomatic and Symptomatic Persons (COVID ARC 19)No longer recruiting/follow-up only18-80 YearsCC Night
20-C-0070A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Patients with Inborn Errors of ImmunityParticipants currently recruited/enrolled4-69 YearsNCI Congenital
19-H-0097A Pilot Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Escalating Multiple Oral Doses of AG-348 in Subjects with Stable Sickle Cell DiseaseCompleted Study; data analyses ongoing18-70 YearsNHLBINight
19-CH-0071An Open-Label Phase 3 Study of the Safety and Efficacy of Pegvisomant in Children with Growth Hormone ExcessParticipants currently recruited/enrolled2-18 YearsNICHDNight
19-CH-0020A Phase 1-2 Multi-Center Study to Assess the Efficacy and Safety of Abiraterone Acetate as Adjunctive Therapy in Pre-Pubescent Children with Classic 21-Hydroxylase DeficiencyRecruitment has not started2-9 YearsNICHDCongenital
19-C-0085Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Peripheral T cell LymphomaClinical hold/Recruitment or enrollment suspended12-125 YearsNCI Congenital
18-N-0083ASPIRO: A Phase 1/2/3, Randomized, Open-Label, Ascending-Dose, Delayed-Treatment Concurrent Control Clinical Study to Evaluate the Safety and Efficacy of AT132, an AAV8-Delivered Gene Therapy in X-Linked Myotubular Myopathy (XLMTM) PatientsNo longer recruiting/follow-up only3-5 YearsNINDSNight
18-H-0108Vascular Disease Discovery ProtocolParticipants currently recruited/enrolled2-100 YearsNHLBIStationary
18-DK-0044Effect of Ultra Processed versus Unprocessed Diets on Energy IntakeCompleted Study; data analyses ongoing18-50 YearsNIDDKStationary
18-CC-0087Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy VolunteersCompleted Study; data analyses ongoing18-65 YearsCC Night
18-CC-0079Pilot RCT of Web-based Behavioral Sleep Intervention for Individuals with Alcohol Use DisorderCompleted Study; data analyses ongoing18-65 YearsCC Night
18-C-0135Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or DysregulationParticipants currently recruited/enrolled4-125 YearsNCI Congenital
18-AA-0047Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)Clinical hold/Recruitment or enrollment suspended18-60 YearsNIAAANight
17-H-0095Heart Catheterization Using Magnetic Resonance Imaging (MRI) Fluoroscopy and Passive GuidewiresParticipants currently recruited/enrolled18-125 YearsNHLBICongenital
17-DK-N004Energy Intake Response to Short-Term Alterations of Energy Expenditure in HumansParticipants currently recruited/enrolled18-55 YearsNIDDKStationary
17-CH-0130Break It Up: A Study Evaluating Breaking Up daily sedentary behavior in youthCompleted Study; data analyses ongoing7-11 YearsNICHDNight
17-C-0158A Feasibility Study of Mobile Sensor Technologies to Assess General Symptomology of Cancer PatientsEnrolling by Invitation18-125 YearsNCI Night
16-N-0058Myalgic Encephalomyelitis/Chronic Fatigue SyndromeCompleted Study; data analyses ongoing18-60 YearsNINDSStationary
16-N-0031An All-Night Functional Magnetic Resonance Imaging Sleep Study With Auditory StimuliParticipants currently recruited/enrolled18-34 YearsNINDSNight
16-C-0003Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesParticipants currently recruited/enrolled4-75 YearsNCI Congenital
16-AA-0059Characterization of Brain Amyloid-beta (A-beta) Retention During Wakefulness And Following Emergence From Sleep In Healthy SubjectsCompleted Study; data analyses ongoing18-40 YearsNIAAANight
15-DK-0192Quantifying Weight Regain and the Persistence of Metabolic Adaptation Following Extreme Weight LossCompleted Study; data analyses ongoing18-125 YearsNIDDKNight
15-DK-0174Dynamic Post-Prandial Metabolism in Patients with Non-Alcoholic Fatty Liver DiseaseCompleted Study; data analyses ongoing18-125 YearsNIDDKNight
15-DK-0108Natural History of Noncirrhotic Portal HypertensionParticipants currently recruited/enrolled12-125 YearsNIDDKCongenital
15-AA-0127(Epi)genetic Modulators of Fear Extinction in Alcohol DependenceParticipants currently recruited/enrolled21-65 YearsNIAAANight
14-HG-0071Clinical and Basic Investigations into Known and Suspected Congenital Disorders of GlycosylationParticipants currently recruited/enrolled1-80 YearsNHGRICongenital
14-HG-0055Study on Moebius Syndrome and Other Congenital Facial Weakness DisordersCompleted Study; data analyses ongoing2-80 YearsNHGRICongenital
14-EI-0064Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye ConditionsParticipants currently recruited/enrolled1-125 YearsNEI Congenital
14-DK-0060Famine from Feast: Linking Vitamin C, Red Blood Cell Fragility, and DiabetesParticipants currently recruited/enrolled18-65 YearsNIDDKBlindness
14-AA-0187Dopamine Rhythms in Health and AddictionClinical hold/Recruitment or enrollment suspended21-55 YearsNIAAANight
13-EI-0049Pathogenesis and Genetics of Microphthalmia, Anophthalmia and Uveal Coloboma ( MAC)Participants currently recruited/enrolled1-125 YearsNEI Blindness
11-EI-0147Longitudinal Investigation of Dark Adaptation in Participants with Age-Related Macular DegenerationParticipants currently recruited/enrolled50-125 YearsNEI Night
11-CH-0078Evaluation of Cortisol Resistance in Young Endurance-Trained and Elderly MenCompleted Study; data analyses ongoing18-30 YearsNICHDNight
10-HG-0065Whole Genome Medical Sequencing for Gene DiscoveryParticipants currently recruited/enrolled0-125 YearsNHGRICongenital
09-H-0225Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease and Beta-ThalassemiaNo longer recruiting/follow-up only2-125 YearsNHLBICongenital
08-C-0130A Phase II Trial of Peginterferon alfa-2b (PEG-Intron) for Neurofibromatosis Type 1 Related Unresectable, Symptomatic or Life-Threatening Plexiform NeurofibromasCompleted Study; data analyses ongoing0-21 YearsNCI Congenital
07-DK-0115Natural History of Type 2 Diabetes Mellitus in Children and Young AdultsCompleted Study; data analyses ongoing8-25 YearsNIDDKStationary
06-H-0072Atorvastatin as a Disease Modifying Agent in Stage II and III Pulmonary Sarcoidosis: A Randomized, Double-Blind, Placebo-Controlled TrialCompleted Study; data analyses ongoing18-70 YearsNHLBIStationary
06-CH-0011Natural History Study of Patients with Excess AndrogenParticipants currently recruited/enrolled0-99 YearsNICHDCongenital
03-H-0282Characterization of Cardiac Function in Subjects with Hereditary Hemochromatosis Who Are New York Heart Association Functional Class ICompleted Study; data analyses ongoing21-100 YearsNHLBIStationary
03-H-0170Nonmyeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation For Severe Congenital Anemias Including Sickle Cell Disease (SCD) and Beta-ThalassemiaParticipants currently recruited/enrolled2-125 YearsNHLBICongenital
02-C-0052Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History StudyParticipants currently recruited/enrolled0-125 YearsNCI Congenital
96-CH-0033An Open, Randomized, Long-Term Clinical Trial of Flutamide, Testolactone, and Reduced Hydrocortisone Dose vs. Conventional Treatment of Children with Congenital Adrenal HyperplasiaNo longer recruiting/follow-up only2-18 YearsNICHDCongenital
94-HG-0132The Phenotype and Etiology of Proteus SyndromeParticipants currently recruited/enrolled0-125 YearsNHGRICongenital
89-M-0006Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy VolunteersParticipants currently recruited/enrolled3-125 YearsNIMH Congenital
88-I-0083Host Response to Infection and Treatment in the Filarial Diseases of HumansParticipants currently recruited/enrolled3-100 YearsNIAIDBlindness
10 Center Drive,Bethesda, MD 20892 | Directions
Privacy Statement | Accessibility | Plain Language | FOIA | Disclaimer
Clinical Center | National Institutes of Health | HHS Vulnerability Disclosure | U.S. Department of Health and Human Services | USA.gov
NIH…Turning Discovery Into Health®