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343 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number Title Protocol Status Min-Max Age Institute Keywords
16-HG-0026New Technology and Child HealthParticipants currently recruited/enrolled18-125 YearsNHGRI16 Multiple Types
09-C-0024A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents and Young AdultsCompleted Study; data analyses ongoing12-26 YearsNCI 16 Multiple Types
000647-CAn Open-label, Multicenter Follow-up Study to Collect Long-term Data on Participants from Multiple Bintrafusp alfa (M7824) Clinical StudiesRecruitment has not started18-125 YearsNCI Multiple Types
000411-CCA Feasibility Pilot Study of a Virtual Education-Based Transition Intervention to Improve Transition Readiness in Adolescent and Young Adults with Congenital Adrenal Hyperplasia.Recruitment has not started16-22 YearsCC 16 Types
000115-CA Trial of the Safety and Immunogenicity of the COVID-19 Vaccine (mRNA-1273) in Participants with Hematologic Malignancies and Various Regimens of Immunosuppression, and in Participants with Solid Tumors on PD1/PDL1 Inhibitor Therapy, Including Booster DParticipants currently recruited/enrolled18-125 YearsNCI 16 Multiple
20-D-0131Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sj(SqrRoot)(Delta)gren's Syndrome; a Phase Ib-IIa Placebo-controlled Clinical Trial and Associated Mechanistic StudiesParticipants currently recruited/enrolled18-75 YearsNIDCR16 Multiple
20-C-0062A phase 1b Study of Nivolumab in Patients with Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)Participants currently recruited/enrolled18-125 YearsNCI 16 Multiple
16-N-0114The Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques: An Investigator-Blinded StudyParticipants currently recruited/enrolled18-125 YearsNINDS16 Multiple
16-N-0055The Pathological Basis of MRI Signal Changes in Multiple Sclerosis: A Longitudinal In Vivo-to-Postmortem StudyParticipants currently recruited/enrolled18-125 YearsNINDS16 Multiple
16-I-0078Microbial, Immune, and Metabolic Perturbations by Antibiotics (MIME study)Participants currently recruited/enrolled18-49 YearsNIAID16 Multiple
16-E-0006Investigating the Impact of Obesity on Pubertal Development in GirlsParticipants currently recruited/enrolled8-14 YearsNIEHS16 Multiple
16-C-0092A Pilot Study of Local Ablative Therapy for Treatment of Oligoprogressive, EGFR-mutated, Non-Small Cell Lung Cancer (NSCLC) After Treatment with Osimertinib (AZD9291, Tagrisso)Completed Study; data analyses ongoing18-125 YearsNCI 16 Types
16-C-0061Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy ProtocolsParticipants currently recruited/enrolled18-125 YearsNCI 16 Multiple
16-C-0047A Phase 1 Trial of Pomalidomide in Combination with Liposomal Doxorubicin in Patients with Advanced or Refractory Kaposi SarcomaParticipants currently recruited/enrolled18-125 YearsNCI 16 Multiple
16-C-0003Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesParticipants currently recruited/enrolled4-75 YearsNCI 16 Multiple
15-C-0078Safety and Feasibility of Stem Cell Gene Transfer Following R-EPOCH for Non-Hodgkin Lymphoma in AIDS Patients Using Peripheral Blood Stem/Progenitor Cells Treated with a Lentivirus Vector-Encoding Multiple Anti-HIV RNAsNo longer recruiting/follow-up only18-65 YearsNCI 16 Multiple
14-I-0091Analysis of Patients Treated for Chronic Granulomatous Disease Since January 1, 1995Completed Study; data analyses ongoing3-125 YearsNIAIDMultiple Types
13-C-0016A Phase I Study of an Adenoviral Transduced Autologous Dendritic Cell Vaccine Expressing Human HER2/neu ECTM in Adults with Tumors with 1-3+ HER2/neu ExpressionCompleted Study; data analyses ongoing18-125 YearsNCI 16 Types
12-C-0193Lymphoid Malignancies and Precursors: Tissue Acquisition ProtocolParticipants currently recruited/enrolled18-125 YearsNCI Multiple Types
00-CH-0136A Trial of Pamidronate in Children with Osteogenesis ImperfectaCompleted Study; data analyses ongoing2-17 YearsNICHDMultiple Types
97-CH-0064Evaluation and Intervention for Ambulation, Growth, and Basilar Invagination in Osteogenesis ImperfectaCompleted Study; data analyses ongoing0-10 YearsNICHDMultiple Types
001126-DCCollection of Clinical Data and Specimens for Research in Hearing, Balance and Communication DisordersParticipants currently recruited/enrolled2-125 YearsNIDCDTypes
001073-ENIEHS Repository of Stored Biological Samples for Future UseRecruitment has not started18-125 YearsNIEHSTypes
001058-DKA Phase 1b/2a Open-label Multiple-ascending Dose Exploratory Study of CRN04894 in ACTH-dependent Cushing's Syndrome (Cushing's Disease or Ectopic ACTH Syndrome)Recruitment has not started18-75 YearsNIDDKMultiple
000975-CCollection of Blood, Bone Marrow, Skin, Saliva, and Stool Samples from Healthy Volunteers Used for Comparative Analysis of Myeloid MalignanciesParticipants currently recruited/enrolled18-125 YearsNCI Types
000954-CA Phase 1/2 Single Arm Open-Label Clinical Trial of TC-510 In Patients with Advanced Mesothelin-Expressing CancerParticipants currently recruited/enrolled18-125 YearsNCI Types
000923-HObservational Study of Cardiac Arrhythmias in Subjects Treated with BTK InhibitorsParticipants currently recruited/enrolled18-110 YearsNHLBIMultiple
000908-DKPeripheral Blood and Urine Immune Cell Phenotyping in Membranous Nephropathy using FACS and Single Cell RNA-seqParticipants currently recruited/enrolled18-125 YearsNIDDKTypes
000865-NNatural History Protocol for Movement DisordersParticipants currently recruited/enrolled2-125 YearsNINDSTypes
000821-IAn Open-Label, Single-Arm, Phase 1/2 Dose-Escalation Trial of Long-Acting Recombinant Human IL-7 (NT-I7, Efineptakin Alfa) for Idiopathic CD4 LymphopeniaRecruitment has not started18-75 YearsNIAIDTypes
000760-HExtension Study (extended access) of Syk-inhibition Using Fostamatinib to Treat Post-Transplant Immune-mediated CytopeniasEnrolling by Invitation18-75 YearsNHLBITypes
000758-HA Phase II Study Using Fostamatinib to Treat Post-Hematopoietic Stem Cell Transplant Immune-Mediated CytopeniasParticipants currently recruited/enrolled18-75 YearsNHLBITypes
000748-DKAnalysis of the Utility of Polygenic Scores for Prediction of Incident Type 2 Diabetes Across Multiple Ancestry GroupsNo longer recruiting/follow-up only0-125 YearsNIDDKMultiple
000740-CHA Phase 3 Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Chronocort in the Treatment of Participants Aged 16 Years and Over with Congenital Adrenal HyperplasiaEnrolling by Invitation18-125 YearsNICHD16
000732-CA Long-Term Follow-Up Study of Patients Who Received VOR33Recruitment has not started18-125 YearsNCI Types
000687-IVRC 322/DMID 21-0016: A Phase I, Dose Escalation, Open-Label Clinical Trial to Evaluate Safety, Tolerability and Immunogenicity of a Nipah Virus (NiV) mRNA Vaccine, mRNA-1215, in Healthy AdultsParticipants currently recruited/enrolled18-60 YearsNIAID16
000686-CHIntrathecal 2-Hydroxypropyl-Beta-Cyclodextrin for Neurological Decline in Patients with Niemann-Pick Disease Type C1Participants currently recruited/enrolled18-125 YearsNICHD16
000665-DKA Randomized Double-Blind Placebo-Controlled Study of the LEPR Agonist Antibody REGN4461 for the Treatment of Metabolic Abnormalities in Patients with Familial Partial LipodystrophyParticipants currently recruited/enrolled18-125 YearsNIDDK16
000644-CPhase 1/1b Trial of ATR Inhibitor BAY 1895344 in Combination with FOLFIRI in GI Malignancies with a Focus on Metastatic Colorectal and Gastric/Gastroesophageal CancersParticipants currently recruited/enrolled18-125 YearsNCI 16
000643-CPhase I/II Study of Pacritinib, A JAK2/IRAK1/CSF1R Inhibitor, in Refractory Chronic Graft-Versus-Host Disease (cGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)Participants currently recruited/enrolled18-125 YearsNCI Multiple
000585-CHAn Open-label Safety, Pharmacokinetic, and Efficacy Study of Miglustat for the Treatment of CLN3 Disease in Patients 17 Years of Age and OlderParticipants currently recruited/enrolled17-125 YearsNICHDCataract
000567-CPhase 1 Trial of Gemcitabine Combined with the BAY 1895344 ATR Inhibitor with Expansion Cohorts in Advanced Pancreatic and Ovarian CancerParticipants currently recruited/enrolled18-125 YearsNCI Types
000527-MCNS Correlates of Extended Sleep RestrictionParticipants currently recruited/enrolled18-39 YearsNIMH Multiple
000489-CPhase I/II Study Using Prophylactic Donor Lymphocyte Infusion Early Post-Transplant After Allogeneic Hematopoietic Cell Transplantation Using Post-Transplantation Cyclophosphamide for High-Risk Hematologic MalignanciesClinical hold/Recruitment or enrollment suspended12-125 YearsNCI Multiple
000483-MPET Imaging of Cyclooxygenases in Multiple SclerosisParticipants currently recruited/enrolled18-99 YearsNIMH Multiple
000462-CPhase 2, Open-label, Single-arm, Window of Opportunity Study of ASP-1929 Photoimmunotherapy with Fluorescence Imaging in Patients With Operable Primary or Recurrent Head and Neck or Cutaneous Squamous Cell CarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Types
000460-IA Randomized, Placebo-controlled Crossover Study to Assess the Safety of Administering a Second Dose of a COVID-19 mRNA Vaccine in Individuals Who Experienced a Systemic Allergic Reaction to an Initial DoseCompleted Study; data analyses ongoing16-69 YearsNIAID16
000444-HVaccine Responses in Patients with B Cell MalignanciesParticipants currently recruited/enrolled18-125 YearsNHLBITypes
000406-AAAddictions Neuroclinical AssessmentEnrolling by Invitation18-125 YearsNIAAA16
000354-CPhase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell CarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Types
000350-DUse of Clear Aligners for the Treatment of Dental Malocclusion In Individuals with Osteogenesis Imperfecta Types III and IVParticipants currently recruited/enrolled12-40 YearsNIDCRTypes
000344-DKNatural History Study of Parathyroid DisordersParticipants currently recruited/enrolled0-125 YearsNIDDKMultiple
000326-HA Phase 1, Dose Escalation, Safety and Tolerability Study of NX- 2127, a Bruton's Tyrosine Kinase (BTK) Degrader, in Adults with Relapsed/Refractory B-cell MalignanciesParticipants currently recruited/enrolled18-125 YearsNHLBITypes
000324-CPhase 1/2 Dose Escalation Study of CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults with Recurrent or Refractory CD19/CD22-expressing B Cell MalignanciesParticipants currently recruited/enrolled3-35 YearsNCI Types
000277-CImaging and Biopsy of HIV-Infected Individuals Undergoing Analytic Treatment InterruptionParticipants currently recruited/enrolled18-125 YearsNCI 16
000264-CA Pharmacodynamics-Driven Trial of Talazoparib, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Aberrations in Genes Involved in DNA Damage ResponseParticipants currently recruited/enrolled18-125 YearsNCI Types
000254-CA Phase II Trial of the Superenhancer Inhibitor Minnelide in Advanced Refractory Adenosquamous Carcinoma of the Pancreas (ASCP)Participants currently recruited/enrolled18-125 YearsNCI Types
000241-CHPhase II Trial of Liraglutide (Saxenda(R), Novo Nordisk) in Adolescents with Obesity After Sleeve Gastrectomy: A Pilot Open-Label StudyParticipants currently recruited/enrolled12-20 YearsNICHD16
000213-HGClinical and Laboratory Study of Rare Skeletal DisordersParticipants currently recruited/enrolled0-125 YearsNHGRITypes
000194-CA Phase I Trial of ProAgio, an anti- alpha-v-beta3 Integrin Cytotoxin, for Previously Treated Advanced Pancreatic Cancer and Other Solid Tumor MalignanciesParticipants currently recruited/enrolled18-125 YearsNCI Types
000193-CPhase 1 Study of Copanlisib with Dose-adjusted EPOCH-R in Relapsed and Refractory Burkitt Lymphoma and other High-Grade B-cell LymphomasClinical hold/Recruitment or enrollment suspended18-125 YearsNCI Types
000183-IAn open-label single-arm Phase IIb study of F901318 as treatment of invasive fungal infections due to Lomentospora prolificans, Scedosporium spp., Aspergillus spp., and other resistant fungi in patients lacking suitable alternative treatment optionsParticipants currently recruited/enrolled16-125 YearsNIAID16
000178-CHyperspectral Analysis of Sweat Metabolite Biometrics for Real-Time Detection of COVID-19Participants currently recruited/enrolled18-125 YearsNCI Multiple
000137-CHImplications of Maternal 45,X Mosaicism As A Secondary Genomic Finding Following Cell-free DNA Sequencing During Pregnancy: A Deep Phenotype StudyRecruitment has not started18-99 YearsNICHDTypes
000123-CCEvaluation of Atherosclerotic Plaques in Abdominal CT StudiesNo longer recruiting/follow-up only0-125 YearsCC 16
000081-CA Phase 2 Study of Anti-PD-L1 Antibody (Atezolizumab) in Chondrosarcoma and Clear Cell SarcomaCompleted Study; data analyses ongoing2-125 YearsNCI Types
000057-CA Phase 1 Study of AZD8186 in Combination with Docetaxel in Patients with PTEN Mutated or PIK3CB Mutated Advanced Solid Tumors, Potentially Amenable to DocetaxelCompleted Study; data analyses ongoing18-125 YearsNCI Types
000045-CA Phase I Trial of T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and other KK-LC-1 Positive Epithelial CancersParticipants currently recruited/enrolled18-120 YearsNCI Types
21-N-0016Phase I/II Study of Teriflunomide in HTLV-1 Associated Myelopathy/Tropical Spastic ParaparesisParticipants currently recruited/enrolled18-125 YearsNINDSMultiple
21-N-0010A Phase 2 Clinical Trial of Tolebrutinib, a Brain-penetrant Bruton's Tyrosine Kinase Inhibitor, for the Modulation of Chronically Inflamed White Matter Lesions in Multiple SclerosisNo longer recruiting/follow-up only18-125 YearsNINDSMultiple
21-I-0029Natural history, epidemiology and pathogenesis of severe HPV-related diseases (Neptune)Participants currently recruited/enrolled3-125 YearsNIAIDMultiple
21-I-0005Phase 1 Study of the Safety and Immunogenicity of an Epstein-Barr virus (EBV) gp350- Ferritin Nanoparticle Vaccine in Healthy Adults With or Without EBV InfectionParticipants currently recruited/enrolled18-29 YearsNIAIDTypes
21-I-0003A Phase 1/2 Study to Evaluate the Safety, Tolerability and Efficacy, of JSP191 for Hematopoietic Cell Transplantation Conditioning to Achieve Engraftment and Immune Reconstitution in Subjects with SCIDParticipants currently recruited/enrolled3-125 YearsNIAIDTypes
21-C-0024A Phase 2 Adaptive Study of Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients with High-Risk Smoldering Multiple MyelomaParticipants currently recruited/enrolled18-125 YearsNCI Multiple
21-C-0021SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin Administered as a 1-Hour Infusion in Ewing Sarcoma Patients in Combination with Low Dose Irinotecan and 3'-Deoxy-3'-18F Fluorothymidine (18F-FLT) ImagingParticipants currently recruited/enrolled6-125 YearsNCI Multiple
21-C-0007A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon CancersParticipants currently recruited/enrolled18-125 YearsNCI Types
20-M-0157PET Imaging of Cyclooxygenase in Participants with Major Depressive Disorder (MDD)Participants currently recruited/enrolled18-70 YearsNIMH 16
20-I-0117Surveillance of Individuals Following SARS-CoV-2 infectionCompleted Study; data analyses ongoing18-125 YearsNIAIDTypes
20-H-0141Long-term Follow-up of Subjects With Sickle Cell Disease Treated With Ex Vivo Gene Therapy Using Autologous Hematopoietic Stem Cells Transduced With a Lentiviral VectorEnrolling by Invitation18-125 YearsNHLBI16
20-DK-0079A Randomized, Double-Blinded, Placebo-Controlled Study of REGN4661, A Leptin Receptor Agonist Antibody, In Patients with Generalized LipodystrophyNo longer recruiting/follow-up only12-125 YearsNIDDK16
20-D-0122A Phase IIb, Open-label Dose-ranging Study Evaluating the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics, and Efficacy of CLTX-305 (encaleret) in Autosomal Dominant Hypocalcemia Type 1 (ADH1)No longer recruiting/follow-up only16-125 YearsNIDCR16
20-D-0094Transmissibility and Viral Load of SARS-CoV-2 Through Oral SecretionsCompleted Study; data analyses ongoing18-125 YearsNIDCRTypes
20-C-0098A Phase 1/2, Open Label, Dose-Escalation, Safety and Tolerability Study of NC410 in Subjects with Advanced or Metastatic Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI 16
20-C-0069A First-In-Human Phase I Single-Agent Dose-Escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System NeoplasmsParticipants currently recruited/enrolled18-125 YearsNCI 16
20-C-0012A Phase I Study of Bintrafusp alfa (M7824) and NHS-IL12 (M9241) Alone and in Combination with Stereotactic Body Radiation Therapy (SBRT) in Adults with Metastatic Non-Prostate Genitourinary MalignanciesParticipants currently recruited/enrolled18-125 YearsNCI Types
19-NR-0098Patient-Centered Assessment of Symptoms and OutcomesParticipants currently recruited/enrolled18-125 YearsNINR Types
19-N-0124Anakinra for the Treatment of Chronically Inflamed White Matter Lesions in Multiple SclerosisParticipants currently recruited/enrolled18-120 YearsNINDSMultiple
19-N-0081A Traveling Subject Study of Replicability in Conventional and Advanced MRI MS BiomarkersCompleted Study; data analyses ongoing18-125 YearsNINDSMultiple
19-I-0140A Phase 1 Evaluation of the Safety of Belimumab in People with Idiopathic CD4 Lymphopenia and Autoantibodies (Phoebe)Participants currently recruited/enrolled18-70 YearsNIAID16
19-I-0022A Prospective, Multicenter Study to Compare and Validate Endoscopic, Histologic, Molecular, and Patient-Reported Outcomes in Pediatric and Adult Patients with Eosinophilic Esophagitis (EoE), Gastritis (EG) and Colitis (EC)Participants currently recruited/enrolled3-125 YearsNIAIDTypes
19-H-0139Investigation of the Natural Progression of Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenia of Undetermined Significance.Participants currently recruited/enrolled18-125 YearsNHLBITypes
19-H-0097A Pilot Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Escalating Multiple Oral Doses of AG-348 in Subjects with Stable Sickle Cell DiseaseCompleted Study; data analyses ongoing18-70 YearsNHLBIMultiple
19-H-0057Multiple Patient Program for Lamprene (clofazimine) for the treatment of Non-Tuberculous Mycobacterial (NTM) Infections- CLAM320B2002MParticipants currently recruited/enrolled18-99 YearsNHLBIMultiple
19-DK-0072Non-Alcoholic Fatty Liver Disease, the Hepatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)Participants currently recruited/enrolled18-125 YearsNIDDK16
19-DA-N019Outcome Inference in the Sensory Preconditioning Task in Opioid-use DisorderParticipants currently recruited/enrolled21-60 YearsNIDA Types
19-C-0142Identifying Predictors of Poor Health-Related Quality-of-Life Among Pediatric Hematopoietic Stem Cell DonorsParticipants currently recruited/enrolled5-125 YearsNCI Multiple
19-C-0135Evaluation of the Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine TumorsParticipants currently recruited/enrolled12-125 YearsNCI Types
19-C-0131Development and Psychometric Testing of a Pediatric Chronic Graft- Versus-Host Disease (GVHD) Symptom Scale (PCSS)Participants currently recruited/enrolled5-125 YearsNCI Multiple
19-C-0112Phase I/II Study De-intensifying Exposure of Post-transplantation Cyclophosphamide as GVHD Prophylaxis after HLA-haploidentical Hematopoietic Cell Transplantation for Hematologic MalignanciesParticipants currently recruited/enrolled12-125 YearsNCI Multiple
19-C-0102A Phase I Clinical Trial of T-cells Expressing an anti-SLAMF7 CAR for Treating Multiple MyelomaCompleted Study; data analyses ongoing18-73 YearsNCI Multiple
19-C-0016Natural History and Biospecimen Acquisition Study for Children and Adults with Rare Solid TumorsParticipants currently recruited/enrolled0-125 YearsNCI 16
19-C-0010A Phase 1 Trial of MK-3475 Plus Ziv-Aflibercept in Patients with Advanced Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Types
19-C-0006Phase II Trial Evaluating Nivolumab In Patients With IDH-Mutant Gliomas With And Without Hypermutator PhenotypeParticipants currently recruited/enrolled18-125 YearsNCI 16
19-AT-0089Sensory Afferents for Deep Pressure SensationCompleted Study; data analyses ongoing18-50 YearsNCCIH16
18-N-0140Clinical Laboratory Evaluation of Chronic Autonomic FailureParticipants currently recruited/enrolled18-125 YearsNINDSMultiple
18-N-0083ASPIRO: A Phase 1/2/3, Randomized, Open-Label, Ascending-Dose, Delayed-Treatment Concurrent Control Clinical Study to Evaluate the Safety and Efficacy of AT132, an AAV8-Delivered Gene Therapy in X-Linked Myotubular Myopathy (XLMTM) PatientsNo longer recruiting/follow-up only3-5 YearsNINDS16
18-M-0144The effects of an ER beta agonist (Lilly Compound LY500307) on estradiol-withdrawal-induced mood symptoms in women with past perimenopausal depression.Participants currently recruited/enrolled45-65 YearsNIMH Types
18-M-0015Development of Non-Invasive Brain Stimulation TechniquesParticipants currently recruited/enrolled18-65 YearsNIMH Multiple
18-I-0139Defining Skin Immunity of a Bite of Key Insect Vectors in HumansCompleted Study; data analyses ongoing18-64 YearsNIAIDMultiple
18-H-0118Technical and Translational Development of Cardiovascular MRI (CMR)Participants currently recruited/enrolled7-125 YearsNHLBIMultiple
18-EI-0068An Investigation of Vitamin A Palmitate Supplementation in Patients with Reticular Pseudodrusen (RPD) and Delayed Dark AdaptationParticipants currently recruited/enrolled50-125 YearsNEI 16
18-EI-0067An Investigation of Vitamin A Palmitate Supplementation in Patients with Age-Related Macular Degeneration (and without reticular pseudodrusen) and Delayed Dark AdaptationParticipants currently recruited/enrolled50-125 YearsNEI 16
18-DA-N095Just-In-Time Adaptive Interventions for Addictive BehaviorsParticipants currently recruited/enrolled18-75 YearsNIDA 16
18-DA-N053Imaging Biomarker for Addiction Treatment OutcomeParticipants currently recruited/enrolled21-125 YearsNIDA 16
18-CH-0120A Natural History of the Collagen-Related Disorder Osteogenesis Imperfecta and the Genotype-Phenotype CorrelationNo longer recruiting/follow-up only0-125 YearsNICHDTypes
18-CH-0002Investigations of Juvenile Neuronal Ceroid Lipofuscinosis (CLN3)Participants currently recruited/enrolled0-125 YearsNICHDMultiple
18-C-0138An Open-Label Phase 2 Study to Evaluate PT2977 for the Treatment of Von Hippel-Lindau Disease-Associated Renal Cell Carcinoma.No longer recruiting/follow-up only18-125 YearsNCI Types
18-C-0125A Phase I Clinical Trial of T cells Expressing a Novel Fully-human Anti-BCMA CAR for Treating Multiple MyelomaNo longer recruiting/follow-up only18-73 YearsNCI Multiple
18-C-0080Feasibility and Preliminary Efficacy of an Enhanced Mindfulness Intervention for Children and Young Adults with High Grade or High-Risk Cancer and Their Caregivers: A Pilot Randomized Controlled TrialCompleted Study; data analyses ongoing5-125 YearsNCI 16
18-C-0078A Phase I/II Study of Immunotherapy Combination BN-Brachyury vaccine, M7824, N-803 and Epacadostat (QuEST1)Participants currently recruited/enrolled18-125 YearsNCI Types
18-C-0062Phase 2 Trial of XL184 (Cabozantinib) an Oral Small-Molecule Inhibitor of Multiple Kinases, in Children and Young Adults with Refractory Sarcomas, Wilms Tumor, and Other Rare TumorsCompleted Study; data analyses ongoing2-30 YearsNCI Multiple
18-C-0058A Pilot Study to Evaluate the Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration in Men with Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy FemalesParticipants currently recruited/enrolled18-125 YearsNCI Multiple
18-C-0049A Phase II Study Using the Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in Patients with Metastatic CancerParticipants currently recruited/enrolled18-72 YearsNCI Multiple
17-I-0083Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)Participants currently recruited/enrolled18-125 YearsNIAIDMultiple
17-CC-0148Obtaining Samples from Human Subjects to Facilitate Basic, Translational and Clinical ResearchParticipants currently recruited/enrolled18-125 YearsCC Multiple
17-C-0149Phase 2 Trial of Pembrolizumab in Relapsed and Refractory Gray-Zone Lymphoma (GZL), Primary Central Nervous System Lymphoma (PCNSL),and Other Extranodal Diffuse Large B-cell LymphomasNo longer recruiting/follow-up only18-125 YearsNCI Types
17-C-0140Phase I/II Evaluation of Oral Decitabine/Tetrahydrouridine as Epigenetic Priming for Pembrolizumab Immune Checkpoint Blockade in Inoperable Locally Advanced or Metastatic Non-Small Cell Lung Cancers, Esophageal Carcinomas, or Pleural MesotheliomasCompleted Study; data analyses ongoing18-99 YearsNCI Multiple
17-C-0125Phase 2 Trial of Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-Hodgkin LymphomasParticipants currently recruited/enrolled12-125 YearsNCI Types
17-C-0049A Phase I/II Trial of the Insulin-Like Growth Factor 1 Receptor (IGF-1R) Antibody AMG479 (Ganitumab) in Combination with the Src Family Kinase (SFK) Inhibitor Dasatinib in Patients with Embryonal and Alveolar RhabdomyosarcomaCompleted Study; data analyses ongoing2-125 YearsNCI Types
17-AT-0075Sensory and Opioid Mechanisms of Affective TouchCompleted Study; data analyses ongoing18-50 YearsNCCIHTypes
16-N-0170Effects of Prism Adaption and rTMS on Brain Connectivity and Visual RepresentationCompleted Study; data analyses ongoing18-75 YearsNINDS16
16-N-0166Deep Brain Stimulation Surgery for Treatment of Focal Hand DystoniaParticipants currently recruited/enrolled22-125 YearsNINDS16
16-N-0072A Pilot Study of Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy with Ex Vivo Generated Polyomavirus-Specific T-cellsCompleted Study; data analyses ongoing18-125 YearsNINDS16
16-N-0064Cholinergic Receptor Imaging in DystoniaCompleted Study; data analyses ongoing18-125 YearsNINDS16
16-N-0058Myalgic Encephalomyelitis/Chronic Fatigue SyndromeCompleted Study; data analyses ongoing18-60 YearsNINDS16
16-N-0041Tumor Related EpilepsyParticipants currently recruited/enrolled8-125 YearsNINDS16
16-N-0031An All-Night Functional Magnetic Resonance Imaging Sleep Study With Auditory StimuliParticipants currently recruited/enrolled18-34 YearsNINDS16
16-I-0165An open-label, non-randomized extension study to evaluate the long term safety, tolerability, efficacy and pharmacokinetics of CDZ173 (leniolisib) in patients with APDS/PASLI (Activated phosphoinositide 3-kinase delta syndrome/p110 delta-activating mutatNo longer recruiting/follow-up only12-75 YearsNIAID16
16-I-0126Genomic Response of Human Immune and Non-Immune Cells to GlucocorticoidsCompleted Study; data analyses ongoing18-64 YearsNIAID16
16-I-0065Screening for Alpha Globin DeletionsParticipants currently recruited/enrolled18-39 YearsNIAID16
16-I-0053A Multicenter Study of the Immunogenicity of Recombinant Vesicular Stomatitis Vaccine for Ebola-Zaire (rVSVdeltaG-ZEBOV GP) for Pre-Exposure Prophylaxis in Individuals at Potential Occupational Risk for Ebola Virus Exposure (PREPARE)No longer recruiting/follow-up only18-125 YearsNIAID16
16-I-0039Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria ChallengeParticipants currently recruited/enrolled18-50 YearsNIAID16
16-I-0032High Dose Peripheral Blood Stem Cell Transplantation with Post Transplant Cyclophosphamide for Patients with Chronic Granulomatous DiseaseNo longer recruiting/follow-up only4-65 YearsNIAID16
16-HG-0156The Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic AcidemiaParticipants currently recruited/enrolled0-125 YearsNHGRI16
16-HG-0017Genomic Services Research ProgramParticipants currently recruited/enrolled0-125 YearsNHGRI16
16-H-0144Impact of Elastin Mediated Vascular Stiffness on End OrgansParticipants currently recruited/enrolled3-85 YearsNHLBI16
16-H-0132CADASIL Disease DiscoveryCompleted Study; data analyses ongoing18-100 YearsNHLBI16
16-H-0129Study to Evaluate the Effect of Nicotinamide Riboside on ImmunityCompleted Study; data analyses ongoing18-39 YearsNHLBI16
16-H-0085Pilot Study to Evaluate the Effect of Fasting and Refeeding on T-Cell FateCompleted Study; data analyses ongoing21-37 YearsNHLBI16
16-H-0074Williams Syndrome (WS) and Supravalvular Aortic Stenosis (SVAS) DNA and Tissue BankParticipants currently recruited/enrolled0-85 YearsNHLBI16
16-H-0063Williams Syndrome Skin and Vascular Elasticity Study (WS-SAVE Study)Completed Study; data analyses ongoing1-70 YearsNHLBI16
16-H-0019High Image Matrix CT ReconstructionCompleted Study; data analyses ongoing18-99 YearsNHLBI16
16-EI-0169A Pilot Study to Investigate Ustekinumab (STELARA) for the Treatment of Active Sight-Threatening UveitisCompleted Study; data analyses ongoing18-125 YearsNEI 16
16-EI-0134Studies of the Natural History, Pathogenesis and Outcome of Ocular DisordersParticipants currently recruited/enrolled0-125 YearsNEI 16
16-EI-0104Clinical and Molecular Studies in Families with Inherited Eye DiseaseParticipants currently recruited/enrolled4-125 YearsNEI 16
16-EI-0090Natural History of Spinocerebellar Ataxia Type 7 (SCA7)Participants currently recruited/enrolled12-125 YearsNEI 16
16-EI-0046Uveitis/Intraocular Inflammatory Disease Biobank (iBank)No longer recruiting/follow-up only8-125 YearsNEI 16
16-EI-0024Rod and Cone Mediated Function in Retinal DiseaseParticipants currently recruited/enrolled5-125 YearsNEI 16
16-E-0157CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)Completed Study; data analyses ongoing18-28 YearsNIEHS16
16-E-0096Cytochrome P450 Epoxygenase Pathway Regulation of Macrophage FunctionParticipants currently recruited/enrolled18-65 YearsNIEHS16
16-DK-0173MEASuRE: Metreleptin Effectiveness and Safety RegistryParticipants currently recruited/enrolled0-125 YearsNIDDK16
16-DK-0143Idiosyncratic Liver Injury Associated with Drugs (ILIAD): A Retrospective StudyParticipants currently recruited/enrolled18-125 YearsNIDDK16
16-DK-0125Evaluation of Adults with Endocrine-Related ConditionsParticipants currently recruited/enrolled18-100 YearsNIDDK16
16-DK-0068The Molecular, Cellular, and Genetic Characterization of Human Adipose Tissue and its Role in MetabolismParticipants currently recruited/enrolled18-125 YearsNIDDK16
16-DK-0038A Randomized, Double Blind, Placebo-Controlled Study to Assess Efficacy, Safety and Tolerability of ISIS 304801 in Patients with Partial Lipodystrophy with an Open-Label ExtensionCompleted Study; data analyses ongoing18-125 YearsNIDDK16
16-DA-N140Effects of a New Behavioral Intervention on Alcohol Craving and DrinkingParticipants currently recruited/enrolled21-65 YearsNIDA 16
16-DA-0080A Novel Compound for Alcoholism Treatment: a Translational Strategy - Part IICompleted Study; data analyses ongoing18-70 YearsNIDA 16
16-D-0040Natural History of Craniofacial Anomalies and Developmental Growth VariantsParticipants currently recruited/enrolled2-125 YearsNIDCR16
16-CH-0164A Phase III Extension Study of Efficacy, Safety and Tolerability of Chronocort (Registered) in the Treatment of Congenital Adrenal HyperplasiaCompleted Study; data analyses ongoing18-80 YearsNICHD16
16-CH-0113Evaluation of Children with Endocrine and Metabolic-Related ConditionsParticipants currently recruited/enrolled0-100 YearsNICHD16
16-CH-0103Evaluation of Patients with Genetic DisordersParticipants currently recruited/enrolled0-125 YearsNICHD16
16-CC-0168Focus Groups to Determine Surrogates' Views Regarding Patient Preference PredictorsCompleted Study; data analyses ongoing18-90 YearsCC 16
16-CC-0162Longitudinal Changes in the Oral and Gut Microbiome of Individuals with Alcohol DependenceCompleted Study; data analyses ongoing18-125 YearsCC 16
16-CC-0149Dopamine and Motor Learning in Cerebral PalsyParticipants currently recruited/enrolled5-25 YearsCC 16
16-CC-0112Impact of Once-Weekly Rifapentine and Isoniazid on the Steady State Pharmacokinetics of Dolutegravir and Darunavir Boosted with Cobicistat in Healthy VolunteersCompleted Study; data analyses ongoing18-65 YearsCC 16
16-CC-0098Pilot Study of Ultrasound Guided Focal Thermal Ablation of Prostate CancerClinical hold/Recruitment or enrollment suspended18-125 YearsCC 16
16-CC-0056Analysis of A Tool to Assess Psycho Social Spiritual Healing: Cognitive InterviewingCompleted Study; data analyses ongoing18-125 YearsCC 16
16-CC-0049A Phase II Study Using LC Bead LUMI Radio-Opaque Embolic Beads to Detect and Characterize the Vascularity of Hepatic Tumors During Treatment with Transarterial Embolization (TAE) Alone or Combined with Thermal AblationEnrolling by Invitation18-125 YearsCC 16
16-CC-0001Evaluation of MiSeq for Microbial Identification in SpecimensEnrolling by Invitation2-125 YearsCC 16
16-C-0171Phase I/II Study of Lenalidomide Combined with Modified DA-EPOCH and Rituximab (EPOCH-R2) in Primary Effusion Lymphoma or KSHV-Associated Large Cell LymphomaParticipants currently recruited/enrolled18-125 YearsNCI 16
16-C-0154A Phase I/II Trial of T Cell Receptor Gene Therapy Targeting HPV-16 E7 for HPV-Associated CancersParticipants currently recruited/enrolled18-125 YearsNCI 16
16-C-0151Evaluation of the Natural History of and Specimen Banking for Patients with Tumors of the Central Nervous SystemParticipants currently recruited/enrolled18-125 YearsNCI 16
16-C-0138Collection of Peripheral Blood Mononuclear Cells (PBMCs) from Healthy Subjects for the Expansion of T Cells for Adoptive Cell TherapyParticipants currently recruited/enrolled18-99 YearsNCI 16
16-C-0135A Pilot Study of Combined Immune Checkpoint Inhibition in combination with Ablative Therapies in Subjects with Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)No longer recruiting/follow-up only18-125 YearsNCI 16
16-C-0131A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced with a CD70-Binding Chimeric Antigen Receptor to Patients with CD70-Expressing CancersParticipants currently recruited/enrolled18-70 YearsNCI 16
16-C-0128A Phase I/II Study of Mesothelin-Targeted Immunotoxin LMB-100 Alone or in Combination with Nab-Paclitaxel in Participants with Previously Treated Metastatic and/ or Locally Advanced Pancreatic Ductal Adenocarcinoma and Mesothelin Expressing Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI 16
16-C-0121A Pilot Clinical Trial of Genomic Based Assignment of Therapy in Advanced Urothelial CarcinomaCompleted Study; data analyses ongoing18-125 YearsNCI 16
16-C-0107A Phase I/II Trial of EP0057, a Nanoparticle Camptothecin with Olaparib in Patients with Relapsed/Refractory Small Cell Lung, Bladder and Prostate CancersParticipants currently recruited/enrolled18-125 YearsNCI 16
16-C-0097Phase 1 Trial of Panobinostat in Children with Diffuse Intrinsic Pontine GliomaCompleted Study; data analyses ongoing2-21 YearsNCI 16
16-C-0094A Phase 1/2 Study of Baricitinib, a JAK1/2 Inhibitor, in Chronic Graft-Versus-Host Disease (cGVHD) after Allogeneic Hematopoietic Stem Cell Transplantation (SCT)No longer recruiting/follow-up only18-125 YearsNCI 16
16-C-0088A Randomized Phase II/III Study of the Combination of Cediranib and Olaparib Compared to Cediranib or Olaparib Alone, or Standard of Care Chemotherapy in Women with Recurrent Platinum-Resistant or -Refractory Ovarian, Fallopian Tube, or Primary PeritoneaCompleted Study; data analyses ongoing18-125 YearsNCI 16
16-C-0087Phase I Study of Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor in Combination with Cisplatin in Patients with Refractory Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI 16
16-C-0081A Phase I Dose Escalation Trial of Re-Irradiation in Good Prognosis Recurrent GlioblastomaNo longer recruiting/follow-up only18-125 YearsNCI 16
16-C-0076Prospective Screening for Patient Specific Genotypes and Phenotypes that Influence Drug Dosing and Trial Selection in Cancer PatientsEnrolling by Invitation18-125 YearsNCI 16
16-C-0073A Phase 2 Study of Olaparib and Cediranib for the Treatment of Recurrent Ovarian CancerCompleted Study; data analyses ongoing18-125 YearsNCI 16
16-C-0066Phase I Study of MK-3475 (Pembrolizumab) in Patients with Human Immunodeficiency Virus (HIV) and Relapsed/Refractory or Disseminated Malignant NeoplasmParticipants currently recruited/enrolled18-125 YearsNCI 16
16-C-0062A Phase I Study of Subcutaneous Recombinant Human IL-15 (S.C. Rhil-15) and Alemtuzumab for Patients with Refractory or Relapsed Chronic and Acute Adult T-Cell Leukemia (ATL)Completed Study; data analyses ongoing18-125 YearsNCI 16
16-C-0060A Phase 1b/2 Study of alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Stem Cell TransplantationParticipants currently recruited/enrolled18-125 YearsNCI 16
16-C-0054T Cells Expressing a Fully-human Anti- CD19 Chimeric Antigen Receptor for Treating B-cell MalignanciesNo longer recruiting/follow-up only18-73 YearsNCI 16
16-C-0048Docetaxel and Prostvac for Metastatic Castration Sensitive Prostate CancerNo longer recruiting/follow-up only18-125 YearsNCI 16
16-C-0043Phase II Trial of the MEK1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate in Adults with Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform NeurofibromasNo longer recruiting/follow-up only18-125 YearsNCI 16
16-C-0035Prostvac in Patients with Biochemically Recurrent Prostate CancerNo longer recruiting/follow-up only18-125 YearsNCI 16
16-C-0034A Phase II Trial of Oral Pazopanib plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) without Prior Bevacizumab Exposure and (B) after Failing Prior BevacizumabCompleted Study; data analyses ongoing18-125 YearsNCI 16
16-C-0027A Prospective Randomized and Phase II Trial for Metastatic Melanoma Using Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of PembrolizumabParticipants currently recruited/enrolled18-70 YearsNCI 16
16-C-0011A Phase I-II Trial of Everolimus and Sorafenib in Patients with Recurrent High-Grade GliomasCompleted Study; data analyses ongoing18-125 YearsNCI 16
16-C-0010Care of the Prostate Cancer Patient and Prospective Procurement of Prostate Cancer TissueParticipants currently recruited/enrolled18-125 YearsNCI 16
16-C-0009Phase II Trial of Carboplatin and Bevacizumab for the Treatment of Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial and Spinal Cord Ependymoma in Adults: A Multi-Center TrialCompleted Study; data analyses ongoing18-125 YearsNCI 16
16-AT-0136Effects of External Ear Stimulation on Pain Perception and MoodParticipants currently recruited/enrolled18-50 YearsNCCIH16
16-AT-0077Clinical and Scientific Assessment of Pain and Painful DisordersParticipants currently recruited/enrolled12-125 YearsNCCIH16
16-AA-0059Characterization of Brain Amyloid-beta (A-beta) Retention During Wakefulness And Following Emergence From Sleep In Healthy SubjectsCompleted Study; data analyses ongoing18-40 YearsNIAAA16
16-AA-0037Effect of Opioid Receptor Modulation on Alcohol Self-Administration and Neural Response to Alcohol Cues in Heavy Drinkers: Role of OPRM1 Gene VariationParticipants currently recruited/enrolled21-60 YearsNIAAA16
15-N-0156In Vivo Characterization of Inflammation with Ferumoxytol, an Ultrasmall Superparamagnetic Iron Oxide Nanoparticle, on 7 Tesla Magnetic Resonance ImagingCompleted Study; data analyses ongoing18-70 YearsNINDSMultiple
15-I-0135An open-label, non-randomized, within-patient dose-finding study followed by a randomized, subject, investigator and sponsor-blinded placebo controlled study to assess the efficacy and safety of CDZ173 (leniolisib) in patients with APDS/PASLI (Activated Completed Study; data analyses ongoing12-75 YearsNIAID16
15-DK-0108Natural History of Noncirrhotic Portal HypertensionParticipants currently recruited/enrolled12-125 YearsNIDDKTypes
15-C-0200Molecular Analysis for Therapy Choice (MATCH) (EAY131)Completed Study; data analyses ongoing18-125 YearsNCI Types
15-C-0142Acceptance and Commitment Training for Adolescents and Adults with Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain: A Phase III Clinical TrialCompleted Study; data analyses ongoing16-59 YearsNCI 16
15-C-0141Gene Therapy Follow up Protocol for Subjects Previously Enrolled in CAR T-Cell StudiesEnrolling by Invitation18-125 YearsNCI Multiple
15-C-0138Phase I Study of Ipilimumab, Nivolumab, and the Combination in Patients with Newly Diagnosed GlioblastomaCompleted Study; data analyses ongoing18-125 YearsNCI 16
15-C-0093Phase I Trial of Turalio(R) (pexidartinib, PLX3397) in Children and Young Adults with Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN)Participants currently recruited/enrolled3-35 YearsNCI Types
15-C-0086Phase I Trial of the Combination of Nilotinib and Paclitaxel in Adults and Pediatric Patients with Refractory Solid TumorsParticipants currently recruited/enrolled12-120 YearsNCI Multiple
15-C-0076A Pilot Study of Long Term TARP Vaccination Using A Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Previously Vaccinated Men on NCI 09-C-0139Completed Study; data analyses ongoing18-125 YearsNCI Types
15-C-0067A Phase I/II Open Label, Dose Escalation Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell TransplantationParticipants currently recruited/enrolled18-125 YearsNCI Multiple
15-C-0019The Impact of Ras/MAPK Signaling Pathway-Targeted Therapies on Neurocognitive Functioning in Individuals with NF1Completed Study; data analyses ongoing4-99 YearsNCI Types
15-AR-0144Studies of Dermatologic Diseases-Biospecimen Acquisition ProtocolParticipants currently recruited/enrolled2-125 YearsNIAMSTypes
15-AA-0186Development of Neuroimaging Methods to Assess the Neurobiology of AddictionParticipants currently recruited/enrolled18-125 YearsNIAAAMultiple
14-I-0206Novel Genetic Disorders of the Immune SystemParticipants currently recruited/enrolled0-99 YearsNIAIDTypes
14-I-0146The Pathogenesis and Genetics of Disseminated or Refractory CoccidioidomycosisParticipants currently recruited/enrolled2-100 YearsNIAIDTypes
14-EI-0064Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye ConditionsParticipants currently recruited/enrolled1-125 YearsNEI 16
13-N-0085Clinical Manifestations and Biorepository for Focal DystoniaCompleted Study; data analyses ongoing18-125 YearsNINDSTypes
13-N-0017Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)Participants currently recruited/enrolled2-125 YearsNINDSMultiple
13-I-0177Natural History Study of the Complications Associated with Allogeneic Hematopoietic Stem Cell TransplantationsCompleted Study; data analyses ongoing2-125 YearsNIAIDTypes
13-I-0157The Natural History of GATA2 Deficiency and Related DisordersParticipants currently recruited/enrolled2-100 YearsNIAIDTypes
13-I-0082Rituximab (Anti-CD20) for the Treatment of Subjects With Anticytokine Autoantibody-Associated DiseasesCompleted Study; data analyses ongoing18-125 YearsNIAIDTypes
13-HG-0158Patient Perspectives and Simulated Clinical InteractionsCompleted Study; data analyses ongoing18-50 YearsNHGRIMultiple
13-DK-0200The Mechanism of Human Non-Shivering Thermogenesis and Basal Metabolic RateParticipants currently recruited/enrolled18-35 YearsNIDDKTypes
13-DK-0091Combination Therapy of Pegylated Interferon Alfa-2a and Tenofovir DF versus Tenofovir DF Monotherapy in HBeAg-Positive and HBeAg-Negative Chronic Hepatitis BCompleted Study; data analyses ongoing18-125 YearsNIDDK16
13-D-0033Diagnosis and Treatment of Patients in Need of Third Molar Removal and Oral Specimen AcquisitionParticipants currently recruited/enrolled16-50 YearsNIDCR16
13-D-0014Bacterial Arrangement in Supragingival BiofilmsCompleted Study; data analyses ongoing18-999 YearsNIDCRTypes
13-CC-0210Evaluating an Extension Assist Knee Ankle Foot Orthosis to Improve Gait in Children with Movement DisordersParticipants currently recruited/enrolled5-125 YearsCC Types
13-C-0132Allogeneic Hematopoietic Stem Cell Transplant for Patients with Mutations in GATA2 or the MonoMAC SyndromeParticipants currently recruited/enrolled8-70 YearsNCI Types
13-C-0105Molecular Profiling-based Assignment of Cancer Therapy for Patients With Advanced Solid TumorsCompleted Study; data analyses ongoing18-120 YearsNCI Types
13-C-0044A Phase 2 Study of Cabozantinib (XL184), a Dual Inhibitor of MET and VEGFR, in Patients With Metastatic Refractory Soft Tissue SarcomaNo longer recruiting/follow-up only18-120 YearsNCI Types
13-AR-0056Stopping Tumor Necrosis Factor-Alpha Inhibitors in Rheumatoid ArthritisCompleted Study; data analyses ongoing18-125 YearsNIAMSTypes
12-N-0122Integrating Genetic and Environmental Risk Scores into an Algorithm to Predict Multiple Sclerosis SusceptibilityCompleted Study; data analyses ongoing18-125 YearsNINDSMultiple
12-N-0095Clinical and Molecular Manifestations of Neuromuscular and Neurogenetic Disorders of ChildhoodParticipants currently recruited/enrolled0-125 YearsNINDSMultiple
12-M-0128TMS Investigations of the Human Visual SystemParticipants currently recruited/enrolled18-50 YearsNIMH Types
12-HG-0022Inherited Diseases, Caregiving, and Social NetworksCompleted Study; data analyses ongoing18-125 YearsNHGRIMultiple
12-H-0035A Phase II study of Ibrutinib for Patients with Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) Who Need Therapy and are Older than 65 or have a 17p DeletionNo longer recruiting/follow-up only18-125 YearsNHLBITypes
12-EI-0042NEI Intramural Biorepository for Retinal DiseasesParticipants currently recruited/enrolled2-125 YearsNEI Types
12-E-0190The Role of Functionally Relevant Cyclooxygenase-2 (COX-2) Gene Single Nucleotide Polymorphisms - 765G>C and 8473T>C in Lymphocyte DifferentiationCompleted Study; data analyses ongoing18-150 YearsNIEHSTypes
12-DC-0152Normative Values in Audiovestibular TestingParticipants currently recruited/enrolled5-80 YearsNIDCDTypes
12-DA-N474Identifying Neurobiological Mechanisms that Underlie Acute Nicotine Withdrawal and Drive Early Relapse in SmokersClinical hold/Recruitment or enrollment suspended18-65 YearsNIDA Multiple
12-CC-0139Estimation of Brain Biomechanics using MRIParticipants currently recruited/enrolled18-65 YearsCC Multiple
12-C-0178Longitudinal Assessment and Natural History Study of Children and Adults with MEN2A or MEN2B with or without Medullary Thyroid CarcinomaParticipants currently recruited/enrolled0-125 YearsNCI Multiple
12-C-0118A Phase II Study of Sunitinib in Patients with Advanced Relapsed or Refractory Thymoma or Thymic Carcinoma with at Least One Prior Line of Platinum-Based Systemic ChemotherapyNo longer recruiting/follow-up only18-100 YearsNCI Types
12-C-0107Carfilzomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma: a Clinical and Correlative Pilot StudyNo longer recruiting/follow-up only18-125 YearsNCI Multiple
12-C-0079A Phase II Multicenter Study of AMG 386 and Abiraterone in Metastatic Castration Resistant Prostate CancerCompleted Study; data analyses ongoing18-125 YearsNCI Types
12-C-0074Mobilization and Collection of Autologous Hematopoietic Progenitor Cell (HPC) for Transplantation (AHCT) for Plasma Cell Myeloma (PCM)Completed Study; data analyses ongoing18-75 YearsNCI Multiple
11-N-0210NIB Repository ProtocolNo longer recruiting/follow-up only5-125 YearsNINDSMultiple
11-M-0251A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying PubertyParticipants currently recruited/enrolled7-35 YearsNIMH Multiple
11-I-0057Effect of Interferon Alpha 2b Intensification on HIV-1 Residual Viremia in Individuals Suppressed on Antiretroviral TherapyCompleted Study; data analyses ongoing18-65 YearsNIAID16
11-H-0134A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R Agonist), Eltrombopag, in Moderate Aplastic Anemia PatientsNo longer recruiting/follow-up only2-125 YearsNHLBI16
11-E-0072Environmental Risk Factors for the Anti-Synthetase SyndromeParticipants currently recruited/enrolled2-100 YearsNIEHSTypes
11-D-0172The Pathogenesis and Natural History of Sjogren's SyndromeParticipants currently recruited/enrolled16-125 YearsNIDCR16
11-CC-0120Stereophotogrammetry of the Torso in Healthy Individuals and Patients with Scoliosis, Chest Wall Deformations, or ObesityCompleted Study; data analyses ongoing2-125 YearsCC Types
11-C-0255Clinical, Epidemiologic, and Genetic Studies of Li-Fraumeni SyndromeParticipants currently recruited/enrolled0-125 YearsNCI Types
11-C-0200A Phase II Trial In Which Patients With Metastatic Alveolar Soft Part Sarcoma Are Randomized to Either Sunitinib or Cediranib Monotherapy, with Cross-Over at Disease ProgressionNo longer recruiting/follow-up only16-125 YearsNCI 16
11-C-0161A Phase I/II Study of the Mitogen Activated Protein Kinase Kinase (MEK) 1 Inhibitor Selumetinib (AZD6244; Hydrogen Sulfate in Children with Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)No longer recruiting/follow-up only2-18 YearsNCI Types
11-C-0140A Phase I Study of Gemcitabine, Carboplatin and Lenalidomide (GCL) for Treatment of Patients with Advanced/Metastatic Urothelial Carcinoma (UC) and Other Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Types
11-C-0061Phase I Trial of Z-Endoxifen in Adults with Refractory Hormone Receptor-Positive Breast Cancer, Desmoid Tumors, Gynecologic Tumors, or other Hormone Receptor-Positive Solid TumorsNo longer recruiting/follow-up only18-125 YearsNCI Types
11-C-0034DICER1-Related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History StudyParticipants currently recruited/enrolled0-125 YearsNCI Types
10-N-0122Evaluation, Pathogenesis, and Outcome of Subjects with or Suspected Traumatic Brain InjuryCompleted Study; data analyses ongoing18-125 YearsNINDSTypes
10-M-0047Top-Down Attentional Control of Visual-ProcessingParticipants currently recruited/enrolled18-125 YearsNIMH Types
10-M-0027Cognitive Neuroscience of Autism Spectrum DisordersParticipants currently recruited/enrolled5-89 YearsNIMH Multiple
10-I-0216Studies of Disorders with Increased Susceptibility to Fungal InfectionsParticipants currently recruited/enrolled0-125 YearsNIAIDTypes
10-H-0141A Phase II Study of Ofatumumab-Based Induction Chemoimmunotherapy Followed by Consolidation Ofatumumab Immunotherapy in Previously Untreated Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.No longer recruiting/follow-up only18-99 YearsNHLBITypes
10-H-0083A Phase I Trial of Safety and Immunogenicity of Gardasil Vaccination Post Stem Cell Transplantation in Patients with and without ImmunosuppressionCompleted Study; data analyses ongoing18-50 YearsNHLBITypes
10-E-0129Study of the Effect of Innate Immunity on the Inflammatory Response to EndotoxinParticipants currently recruited/enrolled18-125 YearsNIEHSTypes
10-DK-0102Clinical and Genetic Studies in Familial Non-Medullary Thyroid CancerParticipants currently recruited/enrolled7-125 YearsNIDDKTypes
10-DA-N457Characterization of Phenotypic and Genotypic RegressorsParticipants currently recruited/enrolled18-125 YearsNIDA Multiple
10-CC-0118Long Term Clinical Correlates of TBI: Imaging, Biomarkers, and Clinical Phenotyping ParametersParticipants currently recruited/enrolled18-125 YearsCC Types
10-C-0174Related and Unrelated Donor Hematopoietic Stem Cell Transplant for DOCK8 DeficiencyParticipants currently recruited/enrolled4-125 YearsNCI Types
10-C-0114A Phase II Study of Bevacizumab and Erlotinib in Subjects with Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell CancerCompleted Study; data analyses ongoing18-125 YearsNCI Types
10-C-0056A Phase I Study of Indenoisoquinolines LMP400 and LMP776 in Adults With Relapsed Solid Tumors and LymphomasCompleted Study; data analyses ongoing18-125 YearsNCI Types
09-M-0176Functional Relevance of Dopamine Receptors in Healthy Controls and Patients with Schizophrenia: Characterization through [11C]NNC-112 and [18F]Fallypride Positron Emission TomographyParticipants currently recruited/enrolled18-90 YearsNIMH Types
09-I-0232FLU 003 Plus: An International Observational Study to Characterize Adults Who Are Hospitalized with Influenza or Other Targeted Respiratory VirusesParticipants currently recruited/enrolled18-125 YearsNIAIDTypes
09-I-0184Studies in the Pathogenesis of Systemic Capillary Leak SyndromeParticipants currently recruited/enrolled0-125 YearsNIAID16
09-I-0126Pathogenesis and Genetic Basis of Physical Induced Urticarial SyndromesParticipants currently recruited/enrolled2-90 YearsNIAIDMultiple
09-I-0032Comprehensive Multimodal Analysis of Patients with Neuroimmunological Diseases of the CNSParticipants currently recruited/enrolled0-99 YearsNIAIDMultiple
09-H-0199A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R agonist), Eltrombopag, in Patients with Low to Int-2 Risk Myelodysplastic Syndrome (MDS)Completed Study; data analyses ongoing18-125 YearsNHLBI16
09-C-0019A Phase I Study of Dasatinib in Combination with Bevacizumab in Advanced Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Types
08-H-0186Safety and the Anti- Tumor Effects of Escalating Doses of Adoptively Infused Ex Vivo Expanded Autologous Natural Killer (NK) Cells Against Metastatic Cancers or Hematological Malignancies Sensitized to NK-TRAIL Cytotoxicity with BortezomibCompleted Study; data analyses ongoing18-70 YearsNHLBIMultiple
08-EI-0043Age-Related Eye Disease Study (AREDS) and AREDS2 Follow-UpNo longer recruiting/follow-up only50-125 YearsNEI Cataract
08-C-0079Natural History Study and Longitudinal Assessment of Children, Adolescents, and Adults with Neurofibromatosis Type 1No longer recruiting/follow-up only0-125 YearsNCI Types
07-N-0122Modulation of Motor Function by Stimulation of the Central and Peripheral Nervous SystemCompleted Study; data analyses ongoing18-125 YearsNINDSTypes
07-E-0012Rituximab in the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)Completed Study; data analyses ongoing2-125 YearsNIEHS16
07-C-0195Phase II Trial of Targeted Immune-Depleting Chemotherapy and Reduced-Intensity Allogeneic Hematopoietic Stem Cell Transplantation Using 8/8 and 7/8 HLA-matched Unrelated Donors and Utilizing Two Graft-versus-Host Disease Prophylaxis Regimens for the TreaCompleted Study; data analyses ongoing18-74 YearsNCI Multiple
06-H-0072Atorvastatin as a Disease Modifying Agent in Stage II and III Pulmonary Sarcoidosis: A Randomized, Double-Blind, Placebo-Controlled TrialCompleted Study; data analyses ongoing18-70 YearsNHLBICataract
06-EI-0236National Ophthalmic Genotyping and Phenotyping Network Stage 1 - Creation of DNA Repository for Inherited Ophthalmic DiseasesNo longer recruiting/follow-up only2-125 YearsNEI Cataract
06-C-0213Tissue Procurement Protocol for the Developmental Therapeutics Clinic, National Cancer Institute (NCI)Participants currently recruited/enrolled0-125 YearsNCI Multiple
05-H-0242A Pilot Study of Alemtuzumab (Campath) in Patients with Relapsed or Refractory Severe Aplastic AnemiaCompleted Study; data analyses ongoing2-110 YearsNHLBITypes
05-H-0130Long-Term Evaluation and Follow Up Care of Patients Treated with Allogeneic Stem Cell TransplantsParticipants currently recruited/enrolled7-80 YearsNHLBIMultiple
05-CC-0216Prospective Assessment of Functional Status, Psychosocial Adjustment, Health Related Quality of Life and the Symptom Experience in Patients Treated with Allogeneic Hematopoietic Stem Cell TransplantationCompleted Study; data analyses ongoing18-125 YearsCC Types
05-CC-0041Endothelial Cell Dysfunction in Pulmonary Arterial Hypertension: Biomarkers, Mechanisms of Disease and Novel Therapeutic TargetsCompleted Study; data analyses ongoing18-125 YearsCC Multiple
04-H-0161Studies of the Natural History of Sickle Cell DiseaseParticipants currently recruited/enrolled2-125 YearsNHLBIMultiple
04-CC-0119Biomarkers and Protein Mass Expression Profiles in Bronchoalveolar Lavage from Patients with Lung InfiltratesParticipants currently recruited/enrolled3-99 YearsCC Types
04-C-0281Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host DiseaseParticipants currently recruited/enrolled1-125 YearsNCI Multiple
04-C-0102Hematologic Malignancy Biology StudyEnrolling by Invitation1-75 YearsNCI Types
04-AR-0205Progression of Spinal Fusion in Ankylosing SpondylitisCompleted Study; data analyses ongoing18-125 YearsNIAMS16
03-I-0263VRC 200: A Multicenter Specimen Collection Protocol to Obtain Human Biological Samples for Research StudiesParticipants currently recruited/enrolled18-125 YearsNIAIDTypes
03-H-0280Disease Pathogenesis and Natural History of Lipid DisordersParticipants currently recruited/enrolled2-100 YearsNHLBITypes
03-H-0170Nonmyeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation For Severe Congenital Anemias Including Sickle Cell Disease (SCD) and Beta-ThalassemiaParticipants currently recruited/enrolled2-125 YearsNHLBI16
03-E-0099Pathogenic Studies In Families With Twins Or Siblings Discordant For Systemic Rheumatic DisordersCompleted Study; data analyses ongoing2-125 YearsNIEHSTypes
03-C-0278A Comparative Study of Pediatric CNS Tumor Activity as Assessed by 18F-FDG PET Imaging and Proton Magnetic Resonance Spectroscopic Imaging (1H-MRSI)Completed Study; data analyses ongoing1-21 YearsNCI Types
03-C-0066Hereditary Leiomyomatosis Renal Cell Cancer (HLRCC): Identification of the Disease Gene, and Characterization of the Predisposition to Renal CancerParticipants currently recruited/enrolled2-125 YearsNCI Multiple
03-AR-0131Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal StudyCompleted Study; data analyses ongoing18-125 YearsNIAMS16
03-AG-0325The Baltimore Longitudinal Study of Aging(BLSA)Participants currently recruited/enrolled20-125 YearsNIA Multiple
02-I-0086Evaluation of Viral Factors and Immune Parameters to Study HIV-Specific ImmunityParticipants currently recruited/enrolled18-125 YearsNIAIDTypes
02-H-0250A Phase I/II Study of HLA-matched Mobilized Peripheral Blood Hematopoietic Stem Cell Transplantation for Advanced Mycosis Fungoides/Sezary Syndrome Using Nonmyeloablative Conditioning with Campath-1HCompleted Study; data analyses ongoing18-125 YearsNHLBIMultiple
02-CH-0311Investigations into Inborn Errors of Cholesterol Synthesis and Related DisordersParticipants currently recruited/enrolled0-125 YearsNICHDCataract
02-C-0268Prospective Study of Prophylactic Salpingo-Oophorectomy and Longitudinal CA-125 Screening Among Women at Increased Genetic Risk of Ovarian CancerCompleted Study; data analyses ongoing19-100 YearsNCI Multiple
02-C-0211Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of MelanomaParticipants currently recruited/enrolled2-125 YearsNCI Types
02-C-0052Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History StudyParticipants currently recruited/enrolled0-125 YearsNCI Types
01-M-0185Effects of Arousal and Stress on Classical ConditioningCompleted Study; data analyses ongoing18-50 YearsNIMH Types
01-H-0122Collection and Storage of Umbilical Cord Hematopoietic Stem Cells for Sickle Cell Disease TherapyParticipants currently recruited/enrolled18-45 YearsNHLBITypes
00-H-0051Cutaneous Tumorigenesis in Patients with Tuberous SclerosisParticipants currently recruited/enrolled18-90 YearsNHLBIMultiple
00-CH-0160Clinical and Molecular Analysis of ACTH-Independent Steroid Hormone Production in Adrenocortical TissueCompleted Study; data analyses ongoing3-70 YearsNICHDTypes
00-CH-0093Diagnosis, Pathophysiology, and Molecular Biology of Pheochromocytoma and ParagangliomaParticipants currently recruited/enrolled3-125 YearsNICHDMultiple
99-H-0050Non-Myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematologic Malignancies in High Risk Patients and in Patients with Debilitating Hematologic DiseasesCompleted Study; data analyses ongoing2-80 YearsNHLBIMultiple
98-D-0145Screening and Natural History of Patients with Polyostotic Fibrous Dysplasia and the McCune-Albright SyndromeParticipants currently recruited/enrolled0-100 YearsNIDCRMultiple
98-CH-0081Clinical and Basic Investigations into Smith-Lemli-Opitz SyndromeCompleted Study; data analyses ongoing0-125 YearsNICHDMultiple
96-I-0052A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients with Suspected Post Treatment Lyme Disease Syndrome and Selected Control PopulationsParticipants currently recruited/enrolled13-125 YearsNIAIDMultiple
95-I-0066Genetic Analysis of Immune DisordersParticipants currently recruited/enrolled0-125 YearsNIAIDTypes
95-CH-0059Definition of the Genotype and Clinical Phenotype of Primary Pigmented Nodular Adrenocortical Disease (PPNAD), Carney Complex, Peutz-Jeghers Syndrome and Related ConditionsCompleted Study; data analyses ongoing3-70 YearsNICHDMultiple
94-HG-0132The Phenotype and Etiology of Proteus SyndromeParticipants currently recruited/enrolled0-125 YearsNHGRIMultiple
94-C-0074Treatment and Natural History Study of Lymphomatoid GranulomatosisParticipants currently recruited/enrolled12-125 YearsNCI 16
92-CH-0034Studies of Growth Deficiency and Growth Hormone Treatment in Children with Osteogenesis Imperfecta Types III and IVCompleted Study; data analyses ongoing3-16 YearsNICHDTypes
91-I-0140Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in HIV-Infected and HIV-Uninfected VolunteersParticipants currently recruited/enrolled18-125 YearsNIAIDTypes
91-AR-0196Studies on the Natural History and Pathogenesis of Polymyositis, Dermatomyositis, and Related DiseasesParticipants currently recruited/enrolled16-125 YearsNIAMS16
89-N-0045Evaluation of Progression in Multiple Sclerosis by Magnetic Resonance Imaging (MRI)Participants currently recruited/enrolled18-125 YearsNINDSMultiple
88-CH-0032Specificity of Mother-Infant Interaction: The Influence of Maternal Age, Employment Status, and Parenthood StatusCompleted Study; data analyses ongoing0-23 YearsNICHDTypes
81-I-0164Procedures to Obtain Plasma, Lymphocytes, or Other Specimens for Research StudiesParticipants currently recruited/enrolled18-125 YearsNIAIDTypes
78-C-0039Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of CancerNo longer recruiting/follow-up only0-125 YearsNCI Multiple