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350 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number
Title
Protocol Status
Min-Max Age
Institute
Keywords
001043-I
Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders
Recruitment has not started
0-125 Years
NIAID
Sleep Syndrome
000547-HG
Observational Study of Advanced Data Analytics in Genetic Conditions
Recruitment has not started
0-125 Years
NHGRI
Advanced Syndrome
20-M-0166
Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and Healthy Pediatric Populations
Participants currently recruited/enrolled
0-8 Years
NIMH
Sleep Syndrome
20-C-0107
Clinical, Genetic, and Epidemiologic Study of Children and Adults with RASopathies
Participants currently recruited/enrolled
0-125 Years
NCI
Sleep Syndrome
20-C-0062
A phase 1b Study of Nivolumab in Patients with Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced Syndrome
19-H-0139
Investigation of the Natural Progression of Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenia of Undetermined Significance.
Participants currently recruited/enrolled
18-125 Years
NHLBI
Advanced Syndrome
16-N-0058
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Completed Study; data analyses ongoing
18-60 Years
NINDS
Sleep Syndrome
16-CH-0103
Evaluation of Patients with Genetic Disorders
Participants currently recruited/enrolled
0-125 Years
NICHD
Sleep Syndrome
15-M-0139
Mapping the Genotype, Phenotype, and Natural History of Phelan McDermid Syndrome
Participants currently recruited/enrolled
1-125 Years
NIMH
Sleep Syndrome
15-C-0157
Phase I/II Trial of Vandetanib in Combination with Metformin in Subjects with HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell Carcinoma
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced Syndrome
14-C-0161
Phase I Trial of the Combination of Bortezomib and Clofarabine in Adults with Refractory Solid Tumors, Lymphomas, or Myelodysplastic Syndromes
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced Syndrome
07-C-0195
Phase II Trial of Targeted Immune-Depleting Chemotherapy and Reduced-Intensity Allogeneic Hematopoietic Stem Cell Transplantation Using 8/8 and 7/8 HLA-matched Unrelated Donors and Utilizing Two Graft-versus-Host Disease Prophylaxis Regimens for the Trea
Completed Study; data analyses ongoing
18-74 Years
NCI
Advanced Syndrome
03-M-0211
Family Study of Affective and Anxiety Spectrum Disorders
Participants currently recruited/enrolled
7-120 Years
NIMH
Sleep Syndrome
02-H-0250
A Phase I/II Study of HLA-matched Mobilized Peripheral Blood Hematopoietic Stem Cell Transplantation for Advanced Mycosis Fungoides/Sezary Syndrome Using Nonmyeloablative Conditioning with Campath-1H
Completed Study; data analyses ongoing
18-125 Years
NHLBI
Advanced Syndrome
01-HG-0109
Natural History Study of the Clinical and Molecular Manifestations of Smith-Magenis Syndrome (SMS)
No longer recruiting/follow-up only
0-125 Years
NHGRI
Sleep Syndrome
001516-C
Phase I Study of Aerosolized Antibiotics and Pembrolizumab in Advanced Non-Small Cell Lung Cancer
Recruitment has not started
10-120 Years
NCI
Advanced
001109-C
Defining the Natural History of Squamous Cell Carcinoma in Fanconi Anemia
Participants currently recruited/enrolled
8-125 Years
NCI
Syndrome
001099-C
A Phase 1/2, First-in-Human, Open-Label, Dose Escalation and Expansion Study of STAR0602, a Selective T Cell Receptor (TCR)-Targeting, Bifunctional Antibody-Fusion Molecule, in Subjects with Unresectable, Locally Advanced, or Metastatic Solid Tumors that
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
001066-DA
Orexin's Role in The Neurobiology of Substance Use Disorder
Participants currently recruited/enrolled
18-60 Years
NIDA
Sleep
001061-H
Observational Study Investigating the Mechanistic Effects of Mitapivat in Subjects with Sickle Cell Disease
Enrolling by Invitation
16-125 Years
NHLBI
Syndrome
001058-DK
A Phase 1b/2a Open-label Multiple-ascending Dose Exploratory Study of CRN04894 in ACTH-dependent Cushing's Syndrome (Cushing's Disease or Ectopic ACTH Syndrome)
Recruitment has not started
18-75 Years
NIDDK
Syndrome
001032-C
BAY 1895344 Plus Topoisomerase-1 (Top1) Inhibitors in Patients with Advanced Solid Tumors, Phase I Studies with Expansion Cohorts in Small Cell Lung Carcinoma (SCLC), Poorly Differentiated Neuroendocrine Carcinoma (PD-NEC) and Pancreatic Adenocarcinoma (
Recruitment has not started
18-125 Years
NCI
Advanced
000975-C
Collection of Blood, Bone Marrow, Skin, Saliva, and Stool Samples from Healthy Volunteers Used for Comparative Analysis of Myeloid Malignancies
Participants currently recruited/enrolled
18-125 Years
NCI
Syndrome
000954-C
A Phase 1/2 Single Arm Open-Label Clinical Trial of TC-510 In Patients with Advanced Mesothelin-Expressing Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000942-M
A Cognitive Test Battery for Intellectual Disabilities
Participants currently recruited/enrolled
4-125 Years
NIMH
Syndrome
000930-C
A Phase 1b/2 Study of HCW9218, a Bifunctional TGF-Beta Antagonist/IL-15 Protein Complex, for Advanced Pancreatic Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000911-DK
Dinner Time for Obesity and Prediabetes (DTOP)
Recruitment has not started
18-50 Years
NIDDK
Sleep
000910-DA
Real-world Momentary Assessment of Kratom use Accompanied by Product Assays: A Natural-history Study for Interdisciplinary Characterization of Kratom use and Pharmacology
Completed Study; data analyses ongoing
18-125 Years
NIDA
Sleep
000908-DK
Peripheral Blood and Urine Immune Cell Phenotyping in Membranous Nephropathy using FACS and Single Cell RNA-seq
Participants currently recruited/enrolled
18-125 Years
NIDDK
Syndrome
000862-CH
Pilot Study of the Use of Functional Near-Infrared Spectroscopy (fNIRS) Combined with Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical Controls
Participants currently recruited/enrolled
0-125 Years
NICHD
Syndrome
000826-C
An Open Label, Randomised, Phase 2 Study to Evaluate the Safety and Efficacy of MTL-CEBPA Administered in Combination with Sorafenib or Sorafenib Alone, in TKI Naive Participants with Previously Treated Advanced Hepatocellular Carcinoma (HCC) and Hepatit
Recruitment has not started
18-125 Years
NCI
Advanced
000821-I
An Open-Label, Single-Arm, Phase 1/2 Dose-Escalation Trial of Long-Acting Recombinant Human IL-7 (NT-I7, Efineptakin Alfa) for Idiopathic CD4 Lymphopenia
Recruitment has not started
18-75 Years
NIAID
Syndrome
000798-D
A Phase 2 Study of Burosumab for Fibroblast Growth Factor-23 Mediated Hypophosphatemia in Fibrous Dysplasia
Participants currently recruited/enrolled
1-125 Years
NIDCR
Syndrome
000783-C
Phase I/Ib Trial Evaluating the Safety and Efficacy of BET Inhibitor, ZEN003694 with PD-1 Inhibitor, Nivolumab with or without CTLA-4 Inhibitor, Ipilumumab in Solid Tumors
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000782-C
A Dose-Escalation and Expansion Study of the Safety and Pharmacokinetics of XL092 as Single-Agent and Combination Therapy in Subjects with Inoperable Locally Advanced or Metastatic Solid Tumors
Recruitment has not started
18-125 Years
NCI
Advanced
000780-D
A Phase 2 Study of Denosumab for Prevention of Skeletal Disease Progression in Children with Fibrous Dysplasia
Participants currently recruited/enrolled
4-14 Years
NIDCR
Syndrome
000756-DK
Phase II Study of Growth Hormone Inhibition Using Pegvisomant In Severe Insulin Resistance
Participants currently recruited/enrolled
18-65 Years
NIDDK
Syndrome
000754-M
NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar Disorder
Participants currently recruited/enrolled
12-70 Years
NIMH
Sleep
000726-C
A Randomized Phase 2 Study of Atezolizumab with or without Selinexor in Alveolar Soft Part Sarcoma (AXIOM)
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000678-C
Rare Tumors and Cancer Predisposition in Individuals and Families
Participants currently recruited/enrolled
0-125 Years
NCI
Sleep
000666-C
A Phase I/II Study of Palbociclib and Sasanlimab for the Treatment of Advanced Clear Cell Renal Cell Carcinoma (ccRCC) or Papillary Renal Cell Carcinoma (pRCC)
Recruitment has not started
18-125 Years
NCI
Advanced
000661-C
Comprehensive Molecular and Clinical Evaluation of Pediatric and Adult Myelodysplastic Syndromes (MDS)
Participants currently recruited/enrolled
0-125 Years
NCI
Syndrome
000644-C
Phase 1/1b Trial of ATR Inhibitor BAY 1895344 in Combination with FOLFIRI in GI Malignancies with a Focus on Metastatic Colorectal and Gastric/Gastroesophageal Cancers
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000596-C
Phase II Study of Olaparib in Subjects with Advanced Pancreatic Acinar Cell Carcinoma
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000580-C
A Phase 1/2, Open Label Dose-Escalation and Expansion Trial of Nkt2152, an Orally Administered Hif2a Inhibitor, to Investigate Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity in Patients with Advanced Clear Cell Renal Cell Carcinoma
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000567-C
Phase 1 Trial of Gemcitabine Combined with the BAY 1895344 ATR Inhibitor with Expansion Cohorts in Advanced Pancreatic and Ovarian Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000556-H
NHLBI-Emory Advanced Cardiac CT Reconstruction
Recruitment has not started
18-125 Years
NHLBI
Advanced
000527-M
CNS Correlates of Extended Sleep Restriction
Participants currently recruited/enrolled
18-39 Years
NIMH
Sleep
000489-C
Phase I/II Study Using Prophylactic Donor Lymphocyte Infusion Early Post-Transplant After Allogeneic Hematopoietic Cell Transplantation Using Post-Transplantation Cyclophosphamide for High-Risk Hematologic Malignancies
Clinical hold/Recruitment or enrollment suspended
12-125 Years
NCI
Syndrome
000487-CH
Natural History Investigation into Biochemical and Phenotypical Aspects of Smith-Lemli-Opitz Syndrome and Related Disorders of Cholesterol Metabolism
Participants currently recruited/enrolled
0-125 Years
NICHD
Syndrome
000486-C
A Phase 1 Trial of the ATR Inhibitor BAY 1895344 in Combination with Cisplatin and with Cisplatin Plus Gemcitabine in Advanced Solid Tumors with an Emphasis on Urothelial Carcinoma
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000484-C
Randomized Phase II Trial of Durvalumab (D) plus Olaparib (O) and Cediranib (C: DOC) Compared to OC or DC or Chemotherapy in Platinum-Resistant Recurrent Ovarian Cancer with Prior Bevacizumab
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000473-C
A Randomized Phase II Study of Systemic Chemotherapy with or without HAI FUDR-Dexamethasone in Patients with Unresectable Intrahepatic Cholangiocarcinoma
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000423-C
Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults with Sickle Cell Disease (SCD): A Pilot Randomized Controlled Trial
Participants currently recruited/enrolled
18-55 Years
NCI
Sleep
000421-AA
Individual Variations of Taste and Smell Perception in Alcohol Use Disorder (AUD)
Recruitment has not started
18-65 Years
NIAAA
Sleep
000418-C
Phase 1/2a, Open-label, Multicenter Study of Intramuscular PRL-02 Depot in Patients with Advanced Prostate Cancer
Participants currently recruited/enrolled
18-120 Years
NCI
Advanced
000404-C
A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects with VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Participants currently recruited/enrolled
18-75 Years
NCI
Syndrome
000387-H
The Natural History of Acquired and Inherited Bone Marrow Failure Syndromes.
Participants currently recruited/enrolled
2-125 Years
NHLBI
Syndrome
000356-C
A Phase I/II Trial of BMS-986253 in Myelodysplastic Syndromes
Participants currently recruited/enrolled
18-125 Years
NCI
Syndrome
000354-C
Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000344-DK
Natural History Study of Parathyroid Disorders
Participants currently recruited/enrolled
0-125 Years
NIDDK
Syndrome
000343-H
Detection of T cell Somatic Mutations in Bone Marrow Failure Using Whole Exome or Targeted Sequencing
Enrolling by Invitation
18-125 Years
NHLBI
Syndrome
000305-C
Exploratory Phase II Study of LAnreotide in Unresectable or Metastatic Pheochromocytoma / PARAganglioma
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000303-C
A Prospective, Multi-Institutional Phase II Trial Evaluating Temozolomide Vs. Temozolomide and Olaparib For Advanced Pheochromocytoma And Paraganglioma
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000297-CH
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Crinecerfont (NBI-74788) in Adult Subjects with Classic Congenital Adrenal Hyperplasia, Followed by Open-Label Treatment
Participants currently recruited/enrolled
18-125 Years
NICHD
Sleep
000291-I
Observational Digital Biomarker Discovery in Respiratory Virus Challenge Studies
Recruitment has not started
18-65 Years
NIAID
Sleep
000264-C
A Pharmacodynamics-Driven Trial of Talazoparib, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Aberrations in Genes Involved in DNA Damage Response
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000261-AA
Mechanisms Underlying Individual Variations of Taste and Smell in Obesity
Participants currently recruited/enrolled
18-65 Years
NIAAA
Sleep
000254-C
A Phase II Trial of the Superenhancer Inhibitor Minnelide in Advanced Refractory Adenosquamous Carcinoma of the Pancreas (ASCP)
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000226-I
Efficacy of Belimumab and Rituximab Compared to Rituximab Alone for the Treatment of Primary Membranous Nephropathy
Participants currently recruited/enrolled
18-75 Years
NIAID
Syndrome
000224-CH
Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea
Participants currently recruited/enrolled
3-12 Years
NICHD
Sleep
000220-DK
Phase II Trial of the Combination of Alpha-lipoic Acid and Mirabegron in Women and in Men with Obesity
Recruitment has not started
18-65 Years
NIDDK
Sleep
000194-C
A Phase I Trial of ProAgio, an anti- alpha-v-beta3 Integrin Cytotoxin, for Previously Treated Advanced Pancreatic Cancer and Other Solid Tumor Malignancies
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000176-C
A Phase I/II Trial of Lurbinectedin with Berzosertib, an ATR Kinase Inhibitor in Small Cell Cancers and High Grade Neuroendocrine Cancers
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000144-C
A Phase I/II Study of Sacituzumab Govitecan plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000141-DC
Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic Targets
Participants currently recruited/enrolled
18-80 Years
NIDCD
Syndrome
000137-CH
Implications of Maternal 45,X Mosaicism As A Secondary Genomic Finding Following Cell-free DNA Sequencing During Pregnancy: A Deep Phenotype Study
Recruitment has not started
18-99 Years
NICHD
Syndrome
000134-I
A Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Trial of Intravenous Zotatifin in Adults with Mild or Moderate Coronavirus Disease 2019 (COVID-19)
Participants currently recruited/enrolled
18-125 Years
NIAID
Syndrome
000118-DK
Prospective Cohort Study to Determine the Response to COVID-19 Vaccination and Prevalence of COVID-19 in Subjects with Chronic Liver Disease
Participants currently recruited/enrolled
18-100 Years
NIDDK
Advanced
000106-CH
Gonadal Tissue Freezing for Fertility Preservation in Individuals at risk for Ovarian Dysfunction and Premature Ovarian Insufficiency
Participants currently recruited/enrolled
4-21 Years
NICHD
Syndrome
000103-C
A Randomized Study Investigating the Pharmacokinetics of Standard Interval Dosing Compared to Extended Interval Dosing of Nivolumab or Pembrolizumab in Locally Advanced or Metastatic Cancers
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000096-C
A Phase II study of Immunotherapy Combination: Irradiated PD-L1 CAR-NK cells plus Pembrolizumab plus N-803 for Subjects with Recurrent/Metastatic Gastric or Head and Neck Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000085-C
Assessing Sleep and Circadian Rhythms in Primary Brain Tumors Patients: An Observational Study
Enrolling by Invitation
18-99 Years
NCI
Sleep
000081-C
A Phase 2 Study of Anti-PD-L1 Antibody (Atezolizumab) in Chondrosarcoma and Clear Cell Sarcoma
Completed Study; data analyses ongoing
2-125 Years
NCI
Advanced
000070-HG
Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study(GENE-FORECAST): Sodium Intervention Trial (SIT)/GENE-FORECAST SIT
Participants currently recruited/enrolled
21-125 Years
NHGRI
Sleep
000059-C
Phase I Study of Intratumor Injection of anti-Mesothelin Immunotoxin LMB-100 with Ipilimumab in Malignant Mesothelioma
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
000057-C
A Phase 1 Study of AZD8186 in Combination with Docetaxel in Patients with PTEN Mutated or PIK3CB Mutated Advanced Solid Tumors, Potentially Amenable to Docetaxel
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
000051-N
NIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)
Participants currently recruited/enrolled
48-70 Years
NINDS
Sleep
000030-C
Phase 2 Study of Bintrafusp alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON).
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
22-C-0004
A Phase II Study of Bevacizumab, Erlotinib and Atezolizumab in Subjects with Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) Associated or Sporadic Papillary Renal Cell Cancer
Participants currently recruited/enrolled
12-125 Years
NCI
Advanced
21-C-0030
Phase I Study of GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Hepatocellular Carcinoma (HCC)
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
21-C-0022
A Phase 2 Single Arm Open-Label Clinical Trial of ADP-A2M4 SPEAR(TM) T Cells in Subjects with Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
Participants currently recruited/enrolled
10-75 Years
NCI
Advanced
21-C-0007
A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
20-NR-0003
A Proof-of-Concept Trial on the Effect of Ketamine on Fatigue
Participants currently recruited/enrolled
18-70 Years
NINR
Syndrome
20-N-0064
An observational study to assess clinical manifestations and biomarkers in amyotrophic lateral sclerosis type 4 and other inherited neurological disorders of RNA processing.
Participants currently recruited/enrolled
5-125 Years
NINDS
Syndrome
20-N-0060
Mechanisms Underlying the Beneficial Effects of Naps on Motor Learning
Participants currently recruited/enrolled
18-80 Years
NINDS
Sleep
20-M-0159
Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder
Participants currently recruited/enrolled
14-25 Years
NIMH
Syndrome
20-M-0082
Phase 1 Study: PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
Participants currently recruited/enrolled
18-99 Years
NIMH
Syndrome
20-I-0132
A Multicentre, Randomised, Double-blind, Parallel-group, Placebo-controlled, 24-week Phase 3 Study with an Open-label Extension to Evaluate the Efficacy and Safety of Benralizumab in Patients with Hypereosinophilic Syndrome (HES)
Participants currently recruited/enrolled
12-130 Years
NIAID
Syndrome
20-I-0117
Surveillance of Individuals Following SARS-CoV-2 infection
Completed Study; data analyses ongoing
18-125 Years
NIAID
Syndrome
20-I-0111
COVID-19-associated Lymphopenia Pathogenesis Study in Blood
Participants currently recruited/enrolled
18-125 Years
NIAID
Syndrome
20-I-0002
Pilot Study of Mepolizumab in Episodic Angioedema with Eosinophilia
Completed Study; data analyses ongoing
18-125 Years
NIAID
Syndrome
20-HG-0034
A Multi-Cohort Phase 2 Dose-Escalation Study of MK-7075 (Miransertib) in Proteus Syndrome
Participants currently recruited/enrolled
3-125 Years
NHGRI
Syndrome
20-EI-0052
A Phase I/IIa Trial for Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated with Age-Related Macular Degeneration
Participants currently recruited/enrolled
55-125 Years
NEI
Sleep
20-DK-0168
LYNC-LD Prospective Multicenter Natural History Study of Lipodystrophy Syndromes to Determine Prevalence, Incidence and Predictors of Diabetes and Severe Hypertriglyceridemia, and their Complications.
Participants currently recruited/enrolled
3-125 Years
NIDDK
Syndrome
20-D-0131
Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sj(SqrRoot)(Delta)gren's Syndrome; a Phase Ib-IIa Placebo-controlled Clinical Trial and Associated Mechanistic Studies
Participants currently recruited/enrolled
18-75 Years
NIDCR
Syndrome
20-CH-0165
Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals with Androgen Insensitivity
Participants currently recruited/enrolled
0-99 Years
NICHD
Syndrome
20-C-0155
Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetics, Immune and Clinical Activity of SX-682 in Combination with BinTrafusp Alfa (M7824 or TGF-beta "Trap"/PD-L1) with CV301 TRICOM in Advanced Solid Tumors (STAT)
No longer recruiting/follow-up only
18-125 Years
NCI
Advanced
20-C-0154
Pilot Study of DS-8201a Pharmacodynamics in Patients with HER2-expressing Advanced Solid Tumors
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
20-C-0138
Phase II Trial of Combination Immunotherapy in Subjects with Advanced Small Bowel and Colorectal Cancers
No longer recruiting/follow-up only
18-125 Years
NCI
Advanced
20-C-0121
Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
20-C-0106
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients with BAP1 Tumor Predisposition Syndrome
Participants currently recruited/enrolled
30-125 Years
NCI
Syndrome
20-C-0104
Phase I/II Trial of HPV Vaccine PRGN-2009 Alone or in Combination with Anti-PD-L1/TGF-Beta Trap (M7824) in Subjects with HPV Positive Cancers
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
20-C-0098
A Phase 1/2, Open Label, Dose-Escalation, Safety and Tolerability Study of NC410 in Subjects with Advanced or Metastatic Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
20-C-0061
Phase I/II study of NHS-IL12 Monotherapy and in Combination with M7824 in Advanced Kaposi Sarcoma
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
20-C-0045
Phase I/II Trial of Combination Immunotherapy in Subjects with Advanced HPV Associated Malignancies
No longer recruiting/follow-up only
18-125 Years
NCI
Advanced
20-C-0023
First-in-Human Phase I Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of Metarrestin (ML-246) in Subjects with Metastatic Solid Tumors
Participants currently recruited/enrolled
12-125 Years
NCI
Advanced
20-C-0011
Phase 1 Study of Recombinant Human IL-15 (rhIL-15) and Mogamulizumab for Patients with Refractory or Relapsed Adult T-Cell Leukemia and Mycosis Fungoides/Sezary Syndrome
Completed Study; data analyses ongoing
18-125 Years
NCI
Syndrome
20-C-0010
Phase II Trial of Radium-223 in Biochemically Recurrent Prostate Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
20-AG-0087
Ketone ester effects on biomarkers of brain metabolism and cognitive performance in cognitively intact adults (Bullet) 55 years old. A double-blinded randomized controlled clinical trial
Participants currently recruited/enrolled
55-125 Years
NIA
Syndrome
19-NR-0098
Patient-Centered Assessment of Symptoms and Outcomes
Participants currently recruited/enrolled
18-125 Years
NINR
Syndrome
19-N-0081
A Traveling Subject Study of Replicability in Conventional and Advanced MRI MS Biomarkers
Completed Study; data analyses ongoing
18-125 Years
NINDS
Advanced
19-M-0107
The Mechanism of Action Underlying Ketamine's Antidepressant Effects: An Investigation of the AMPA Throughput Theory in Patients with Treatment-Resistant Major Depression
Participants currently recruited/enrolled
18-70 Years
NIMH
Sleep
19-M-0054
Mapping the Phenotype in Adults with Phelan-McDermid Syndrome
Completed Study; data analyses ongoing
0-125 Years
NIMH
Syndrome
19-I-0133
Paradoxical Tuberculosis Reactions in Patients without HIV Infection
Participants currently recruited/enrolled
18-125 Years
NIAID
Syndrome
19-I-0084
Skin Immunity Sample Collection Involving Blisters and Biopsies
Recruitment has not started
7-65 Years
NIAID
Syndrome
19-H-0034
Exploratory Study of Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome
Completed Study; data analyses ongoing
18-70 Years
NHLBI
Syndrome
19-DK-0066
The Evaluation and Management of Endocrine-Related Conditions and Physiology
Participants currently recruited/enrolled
18-90 Years
NIDDK
Sleep
19-CH-0051
Long-Term Follow-UP of Survivors of Pediatric Cushing Disease
Participants currently recruited/enrolled
2-90 Years
NICHD
Syndrome
19-CH-0026
Randomized, Double-Blind, Placebo-Controlled Study Plus Open Label Extension with a Double-Blind, Placebo-Controlled, Randomized Withdrawal Period of Diazoxide Choline Extended-Release Tablets (DCCR, Soleno Therapeutics, Inc.) in Participants with Prader
No longer recruiting/follow-up only
4-125 Years
NICHD
Syndrome
19-CH-0020
A Phase 1-2 Multi-Center Study to Assess the Efficacy and Safety of Abiraterone Acetate as Adjunctive Therapy in Pre-Pubescent Children with Classic 21-Hydroxylase Deficiency
Recruitment has not started
2-9 Years
NICHD
Syndrome
19-C-0143
A Phase II Study Using the Administration of Autologous T-Cells Engineered using the Sleeping Beauty Transposon/Transposase System to Express T-Cell Receptors Reactive Against Mutated Neoantigens in Patients with Metastatic Cancer
Participants currently recruited/enrolled
18-70 Years
NCI
Sleep
19-C-0137
A Phase II Study of Ipilimumab, Cabozantinib, and NIvolumab in Rare Genitourinary Cancers (ICONIC)
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
19-C-0135
Evaluation of the Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors
Participants currently recruited/enrolled
12-125 Years
NCI
Syndrome
19-C-0129
A Phase II Study of Intraperitoneal and Intravenous Paclitaxel Chemotherapy with Oral Capecitabine for Gastric Adenocarcinoma with Peritoneal Carcinomatosis
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
19-C-0128
A Phase I Study of Mesothelin-Targeted Immunotoxin LMB-100 in Combination with Tofacitinib in Persons with Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and other Mesothelin Expressing Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
19-C-0127
A Phase II Study of LMB-100 Followed by Pembrolizumab in the Treatment of Adults with Mesothelin-Expressing Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
No longer recruiting/follow-up only
18-125 Years
NCI
Advanced
19-C-0117
A Phase 1 / 2 Single Arm Open-label Clinical Trial of Gavocabtagene Autoleucel (gavo-cel) in Patients with Advanced Mesothelin Expressing Cancer
Participants currently recruited/enrolled
18-120 Years
NCI
Advanced
19-C-0094
A Phase II Study of Combined Treatment of Durvalumab, Bevacizumab, Tremelimumab and Transarterial Chemoembolization (TACE) in Subjects with Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinoma (BTC)
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
19-C-0076
A Phase 1 Study of Interleukin-15 in Combination with Avelumab (Bavencio) in Relapsed/Refractory Mature T-cell Malignancies
Completed Study; data analyses ongoing
18-125 Years
NCI
Syndrome
19-C-0040
Natural History Study of Men at High Genetic Risk for Prostate Cancer
Participants currently recruited/enrolled
30-75 Years
NCI
Syndrome
19-C-0016
Natural History and Biospecimen Acquisition Study for Children and Adults with Rare Solid Tumors
Participants currently recruited/enrolled
0-125 Years
NCI
Syndrome
19-C-0010
A Phase 1 Trial of MK-3475 Plus Ziv-Aflibercept in Patients with Advanced Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
18-N-0133
Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery
Participants currently recruited/enrolled
18-125 Years
NINDS
Sleep
18-H-0090
Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH using Peripheral Blood Stem Cells and post-transplant Cyclophosphamide for GVHD prophylaxis
Participants currently recruited/enrolled
4-75 Years
NHLBI
Syndrome
18-EI-0055
A Phase III Multicenter Randomized Sham Controlled Study to Determine the Safety and Efficacy of NT-501 in Macular Telangiectasia Type 2
Completed Study; data analyses ongoing
21-80 Years
NEI
Sleep
18-DK-0044
Effect of Ultra Processed versus Unprocessed Diets on Energy Intake
Completed Study; data analyses ongoing
18-50 Years
NIDDK
Sleep
18-CH-0120
A Natural History of the Collagen-Related Disorder Osteogenesis Imperfecta and the Genotype-Phenotype Correlation
No longer recruiting/follow-up only
0-125 Years
NICHD
Sleep
18-CC-0079
Pilot RCT of Web-based Behavioral Sleep Intervention for Individuals with Alcohol Use Disorder
Completed Study; data analyses ongoing
18-65 Years
CC
Sleep
18-C-0126
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice)
Completed Study; data analyses ongoing
1-21 Years
NCI
Advanced
18-C-0122
Phase 1B Study of Copanlisib in Combination with Nivolumab or with Nivolumab and Ipilimumab
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
18-C-0078
A Phase I/II Study of Immunotherapy Combination BN-Brachyury vaccine, M7824, N-803 and Epacadostat (QuEST1)
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
18-C-0058
A Pilot Study to Evaluate the Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration in Men with Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy Females
Participants currently recruited/enrolled
18-125 Years
NCI
Sleep
18-C-0034
A Phase 2 Study of ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
18-C-0014
Phase I Trial of 5-aza-4'-thio-2'-Deoxycytidine (Aza-TdC) in Patients with Advanced Solid Tumors
Participants currently recruited/enrolled
18-120 Years
NCI
Advanced
18-C-0008
Phase III Randomized Adjuvant study of Pembrolizumab in muScle invaSive and locAlly aDvanced urOthelial caRcinoma (AMBASSADOR) versus Observation
No longer recruiting/follow-up only
18-125 Years
NCI
Advanced
18-AR-0081
Investigation of the Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease and Related Inflammatory Conditions
Participants currently recruited/enrolled
0-125 Years
NIAMS
Syndrome
17-N-0131
Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Participants currently recruited/enrolled
18-125 Years
NINDS
Syndrome
17-N-0035
Clinical and Physiological Studies of Tremor Syndromes
Completed Study; data analyses ongoing
18-125 Years
NINDS
Syndrome
17-M-0060
Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
Participants currently recruited/enrolled
18-65 Years
NIMH
Sleep
17-H-0162
Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments: A Multi-Level, Community-Based Physical Activity Intervention
Participants currently recruited/enrolled
21-75 Years
NHLBI
Sleep
17-H-0091
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS using CordIn, Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells, to Expedite Engraftment and Improve Transplant Outcome
Participants currently recruited/enrolled
4-75 Years
NHLBI
Syndrome
17-EI-0008
The Natural History of Geographic Atrophy Associated with Age-Related Macular Degeneration
Participants currently recruited/enrolled
55-125 Years
NEI
Advanced
17-DK-0054
The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment with Beta3-Adrenergic Receptor Agonists
Participants currently recruited/enrolled
18-40 Years
NIDDK
Syndrome
17-DA-0093
Exploring Gut-Brain and Brain-Gut Interactions in Alcohol Use Disorder via Microbiota Investigations: A Pilot Study
Completed Study; data analyses ongoing
21-70 Years
NIDA
Sleep
17-CH-0078
Setmelanotide (RM-493; Rhythm Pharmaceuticals, Inc.) Phase 2 Open-Label Treatment Trials in Patients with Rare Genetic Disorders of Obesity
No longer recruiting/follow-up only
6-100 Years
NICHD
Syndrome
17-C-0140
Phase I/II Evaluation of Oral Decitabine/Tetrahydrouridine as Epigenetic Priming for Pembrolizumab Immune Checkpoint Blockade in Inoperable Locally Advanced or Metastatic Non-Small Cell Lung Cancers, Esophageal Carcinomas, or Pleural Mesotheliomas
Completed Study; data analyses ongoing
18-99 Years
NCI
Advanced
17-C-0117
A Phase 1/2a, Open-Label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-Tumor Activity of PEN-866 in Advanced Solid Malignancies
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
17-C-0092
A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination with Immune Checkpoint Inhibition in Refractory Colorectal Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
17-C-0087
Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma
Participants currently recruited/enrolled
18-125 Years
NCI
Syndrome
17-C-0074
A Phase 2 Study of Anti-PD-L1 Antibody Atezolizumab in Alveolar Soft Part Sarcoma
Participants currently recruited/enrolled
2-125 Years
NCI
Advanced
17-C-0070
Phase II Trial of Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer with Positive Peritoneal Cytology
Participants currently recruited/enrolled
18-125 Years
NCI
Sleep
17-C-0048
Anti-CD30 CAR T Cells with Fully-human Binding Domains for Treating CD30-expressing Lymphomas Including Anaplastic Large Cell Lymphomas
Completed Study; data analyses ongoing
18-73 Years
NCI
Advanced
17-C-0043
Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer
Participants currently recruited/enrolled
2-125 Years
NCI
Syndrome
17-C-0012
A Phase I Study of a Combination of MM-398 and Veliparib in solid tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
17-AA-0152
Ketogenic Diet (KD) in Alcoholism
Participants currently recruited/enrolled
18-125 Years
NIAAA
Sleep
16-N-0031
An All-Night Functional Magnetic Resonance Imaging Sleep Study With Auditory Stimuli
Participants currently recruited/enrolled
18-34 Years
NINDS
Sleep
16-I-0165
An open-label, non-randomized extension study to evaluate the long term safety, tolerability, efficacy and pharmacokinetics of CDZ173 (leniolisib) in patients with APDS/PASLI (Activated phosphoinositide 3-kinase delta syndrome/p110 delta-activating mutat
No longer recruiting/follow-up only
12-75 Years
NIAID
Syndrome
16-I-0078
Microbial, Immune, and Metabolic Perturbations by Antibiotics (MIME study)
Participants currently recruited/enrolled
18-49 Years
NIAID
Sleep
16-H-0144
Impact of Elastin Mediated Vascular Stiffness on End Organs
Participants currently recruited/enrolled
3-85 Years
NHLBI
Syndrome
16-H-0074
Williams Syndrome (WS) and Supravalvular Aortic Stenosis (SVAS) DNA and Tissue Bank
Participants currently recruited/enrolled
0-85 Years
NHLBI
Syndrome
16-H-0063
Williams Syndrome Skin and Vascular Elasticity Study (WS-SAVE Study)
Completed Study; data analyses ongoing
1-70 Years
NHLBI
Syndrome
16-CH-0113
Evaluation of Children with Endocrine and Metabolic-Related Conditions
Participants currently recruited/enrolled
0-100 Years
NICHD
Sleep
16-C-0135
A Pilot Study of Combined Immune Checkpoint Inhibition in combination with Ablative Therapies in Subjects with Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)
No longer recruiting/follow-up only
18-125 Years
NCI
Advanced
16-C-0128
A Phase I/II Study of Mesothelin-Targeted Immunotoxin LMB-100 Alone or in Combination with Nab-Paclitaxel in Participants with Previously Treated Metastatic and/ or Locally Advanced Pancreatic Ductal Adenocarcinoma and Mesothelin Expressing Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
16-C-0121
A Pilot Clinical Trial of Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
16-C-0087
Phase I Study of Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor in Combination with Cisplatin in Patients with Refractory Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
16-C-0066
Phase I Study of MK-3475 (Pembrolizumab) in Patients with Human Immunodeficiency Virus (HIV) and Relapsed/Refractory or Disseminated Malignant Neoplasm
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
16-C-0060
A Phase 1b/2 Study of alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Stem Cell Transplantation
Participants currently recruited/enrolled
18-125 Years
NCI
Syndrome
16-C-0054
T Cells Expressing a Fully-human Anti- CD19 Chimeric Antigen Receptor for Treating B-cell Malignancies
No longer recruiting/follow-up only
18-73 Years
NCI
Advanced
16-C-0047
A Phase 1 Trial of Pomalidomide in Combination with Liposomal Doxorubicin in Patients with Advanced or Refractory Kaposi Sarcoma
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
16-AA-0059
Characterization of Brain Amyloid-beta (A-beta) Retention During Wakefulness And Following Emergence From Sleep In Healthy Subjects
Completed Study; data analyses ongoing
18-40 Years
NIAAA
Sleep
15-M-0188
The Neurobiology of Suicide
Participants currently recruited/enrolled
18-70 Years
NIMH
Sleep
15-M-0109
Checking out Checking In: The Development and Validation of an Electronic Screening Tool for Pediatric Psychosocial Distress
Participants currently recruited/enrolled
8-21 Years
NIMH
Sleep
15-I-0162
Natural History and Genetics of Food Allergy and Related Conditions
Participants currently recruited/enrolled
0-99 Years
NIAID
Syndrome
15-I-0135
An open-label, non-randomized, within-patient dose-finding study followed by a randomized, subject, investigator and sponsor-blinded placebo controlled study to assess the efficacy and safety of CDZ173 (leniolisib) in patients with APDS/PASLI (Activated
Completed Study; data analyses ongoing
12-75 Years
NIAID
Syndrome
15-I-0056
Collection of Plasma from Subjects that Recovered From or Were Vaccinated To Emerging Infectious Diseases
Enrolling by Invitation
18-70 Years
NIAID
Syndrome
15-EI-0202
Evaluation of Oral Minocycline in the Treatment of Geographic Atrophy Associated with Age-Related Macular Degeneration
No longer recruiting/follow-up only
55-125 Years
NEI
Advanced
15-DK-0174
Dynamic Post-Prandial Metabolism in Patients with Non-Alcoholic Fatty Liver Disease
Completed Study; data analyses ongoing
18-125 Years
NIDDK
Syndrome
15-DK-0108
Natural History of Noncirrhotic Portal Hypertension
Participants currently recruited/enrolled
12-125 Years
NIDDK
Syndrome
15-DK-0100
A Multidisciplinary Approach to Deciphering the Mechanisms Involved In Microbial Translocation Across the Spectrum of HCV Associated Liver Fibrosis
Completed Study; data analyses ongoing
18-125 Years
NIDDK
Advanced
15-D-0051
Characterization of Diseases with Salivary Gland Involvement
Participants currently recruited/enrolled
4-125 Years
NIDCR
Syndrome
15-CH-0096
Children's Growth and Behavior Study
Participants currently recruited/enrolled
8-125 Years
NICHD
Sleep
15-C-0160
A Phase I Study of Cabozantinib Plus Nivolumab (CaboNivo) Alone or in Combination with Ipilimumab (CaboNivoIpi) in Patients with Advanced/Metastatic Urothelial Carcinoma and other Genitourinary Tumors
No longer recruiting/follow-up only
18-125 Years
NCI
Advanced
15-C-0145
Phase I/II Study of the Anti-Programmed Death Ligand-1 Antibody Durvalumab (MEDI4736) in Combination with Olaparib and/or Cediranib for Advanced Solid Tumors and Advanced or Recurrent Ovarian, Triple Negative Breast, Lung, Prostate and Colorectal Cancers
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
15-C-0124
Neoadjuvant Androgen Deprivation and Enzalutamide: Using Multiparametric MRI to Evaluate Intraprostatic Tumor Responses and Androgen Resistance Patterns in Newly Diagnosed Prostate Cancer
No longer recruiting/follow-up only
18-125 Years
NCI
Advanced
15-C-0116
Phase I Trial of 4'-thio-2'-deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors
Clinical hold/Recruitment or enrollment suspended
18-125 Years
NCI
Advanced
15-C-0086
Phase I Trial of the Combination of Nilotinib and Paclitaxel in Adults and Pediatric Patients with Refractory Solid Tumors
Participants currently recruited/enrolled
12-120 Years
NCI
Advanced
15-C-0067
A Phase I/II Open Label, Dose Escalation Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation
Participants currently recruited/enrolled
18-125 Years
NCI
Syndrome
15-AA-0031
Human Brain Mapping of the Apparent Diffusion Coefficient (ADC) during Sleep and Wakefulness
Completed Study; data analyses ongoing
18-60 Years
NIAAA
Sleep
14-N-0086
Deep Brain Stimulation Therapy in Movement Disorders
Participants currently recruited/enrolled
18-125 Years
NINDS
Syndrome
14-I-0185
A Phase III Double-Blind Randomized Crossover Study of Plerixafor Versus G-CSF in the Treatment of Patients with WHIM Syndrome.
Completed Study; data analyses ongoing
10-75 Years
NIAID
Syndrome
14-I-0124
PET Imaging and Lymph Node Assessment of IRIS in Persons With AIDS
Participants currently recruited/enrolled
18-125 Years
NIAID
Syndrome
14-I-0081
A Phase 2a Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Subcutaneous Benralizumab (MEDI-563) in Reducing Eosinophilia in Subjects with Hypereosinophilic Syndrome (HES)
No longer recruiting/follow-up only
18-75 Years
NIAID
Syndrome
14-I-0063
An Open-Label, Proof-of-Concept Study to Evaluate the Safety and Efficacy of Dexpramipexole (KNS-760704) in Subjects with Hypereosinophilic Syndrome
No longer recruiting/follow-up only
18-125 Years
NIAID
Syndrome
14-I-0020
Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models
Participants currently recruited/enrolled
18-65 Years
NIAID
Syndrome
14-I-0009
Characterization and Management of Patients with HIV-1 Infection Who Experience Virologic Failure Despite Combination Antiretroviral Therapy
Completed Study; data analyses ongoing
18-100 Years
NIAID
Syndrome
14-HG-0055
Study on Moebius Syndrome and Other Congenital Facial Weakness Disorders
Completed Study; data analyses ongoing
2-80 Years
NHGRI
Syndrome
14-CH-0028
Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in Patients with Ectopic Cushing Syndrome
Participants currently recruited/enrolled
18-80 Years
NICHD
Syndrome
14-CC-0143
Sleep Disturbance and Relapse in Individuals with Alcohol Dependence: An Exploratory Mixed Methods Study
Completed Study; data analyses ongoing
18-125 Years
CC
Sleep
14-CC-0027
The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients with Interstitial Lung Disease
Participants currently recruited/enrolled
21-80 Years
CC
Advanced
14-C-0156
A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) In BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, and High Grade Serous Ovarian Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Syndrome
14-C-0104
A Phase II Study Using Autologous Young Tumor-Infiltrating Lymphocytes Derived from Patients with Non-Small Cell Lung Cancer Following Non-Myeloablative Lymphocyte Depleting Preparative Regimen
Participants currently recruited/enrolled
18-70 Years
NCI
Advanced
14-C-0079
An Exploratory Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults with Cancer and Other Chronic Illnesses
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
14-C-0056
Collection of Blood from Patients with Ovarian, Primary Peritoneal or Fallopian Tube Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
14-C-0037
A Phase 2 Study of the MET Kinase Inhibitor INC280 in Papillary Renal Cell Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
14-C-0015
Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA Mutations
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
14-C-0001
Phase II Study of Axitinib (AG-013736) with Evaluation of the VEGF-pathway in Metastatic, Recurrent or Primary Unresectable Pheochromocytoma/Paraganglioma
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
14-AA-0144
Reliability Of The Human Brain Connectome
Participants currently recruited/enrolled
18-125 Years
NIAAA
Sleep
13-N-0017
Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)
Participants currently recruited/enrolled
2-125 Years
NINDS
Syndrome
13-M-0028
Diagnosis of Childhood-onset Behavioral Disorders, Neuropsychiatric Disorders and Neurodevelopmental Disorders
Participants currently recruited/enrolled
0-99 Years
NIMH
Sleep
13-I-0157
The Natural History of GATA2 Deficiency and Related Disorders
Participants currently recruited/enrolled
2-100 Years
NIAID
Syndrome
13-HG-0199
NIH Participation to USIDNET Registry
Participants currently recruited/enrolled
0-125 Years
NHGRI
Syndrome
13-H-0116
A Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units (CBUs) Manufactured by the National Cord Blood Program (NCBP) and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients
Participants currently recruited/enrolled
4-125 Years
NHLBI
Syndrome
13-H-0059
Longitudinal Observational Study of Severe Asthma
Participants currently recruited/enrolled
18-125 Years
NHLBI
Sleep
13-EI-0049
Pathogenesis and Genetics of Microphthalmia, Anophthalmia and Uveal Coloboma ( MAC)
Participants currently recruited/enrolled
1-125 Years
NEI
Advanced
13-CC-0099
Vasti Control of Patellofemoral Kinematics in Patients with Chronic Patellofemoral Pain.
Participants currently recruited/enrolled
18-55 Years
CC
Syndrome
13-C-0175
A Phase II Protocol for Subjects with Stage T1 Bladder Cancer to Evaluate Selective Bladder Preserving Treatment by Radiation Therapy Concurrent with Radio-sensitizing Chemotherapy following a Thorough Transurethral Surgical Re-Staging
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
13-C-0153
A Phase II Trial of Enzalutamide in Combination with PSA-TRICOM in Patients with Non-Metastatic Castration Sensitive Prostate Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
13-C-0146
A Randomized Phase II Trial Combining Vaccine Therapy with PROSTVAC /TRICOM and Enzalutamide vs. Enzalutamide Alone in Men with Metastatic Castration Resistant Prostate Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
13-C-0132
Allogeneic Hematopoietic Stem Cell Transplant for Patients with Mutations in GATA2 or the MonoMAC Syndrome
Participants currently recruited/enrolled
8-70 Years
NCI
Syndrome
13-C-0118
A Phase I/II Trial of TRC102 (methoxyamine HCl) in Combination with Temozolomide in Patients with Relapsed Solid Tumors and Lymphomas
Participants currently recruited/enrolled
18-125 Years
NCI
Advanced
13-C-0105
Molecular Profiling-based Assignment of Cancer Therapy for Patients With Advanced Solid Tumors
Completed Study; data analyses ongoing
18-120 Years
NCI
Advanced
13-C-0095
A Phase 2 Study of GI-6207 in Patients with Recurrent Medullary Thyroid Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
12-N-0137
A Phase 1 Open-Label Dose Escalation Safety Study of Convection Enhanced Delivery (CED) of Adeno-Associated Virus Encoding Glial Cell Line-Derived Neurotrophic Factor (AAV2-GDNF) in Subjects with Advanced Parkinson's Disease.
Completed Study; data analyses ongoing
18-125 Years
NINDS
Advanced
12-HG-0181
The Clinical Study of Patients with Sex Chromosome Variants
Completed Study; data analyses ongoing
18-125 Years
NHGRI
Syndrome
12-H-0064
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients with Hematologic Malignancies and Other Indications
Participants currently recruited/enrolled
4-75 Years
NHLBI
Syndrome
12-EI-0042
NEI Intramural Biorepository for Retinal Diseases
Participants currently recruited/enrolled
2-125 Years
NEI
Syndrome
12-E-0050
The Role of Gonadotropin Pulsations in the Regulation of Puberty and Fertility
Participants currently recruited/enrolled
14-125 Years
NIEHS
Syndrome
12-E-0049
The Molecular Basis of Inherited Reproductive Disorders
Participants currently recruited/enrolled
0-125 Years
NIEHS
Syndrome
12-C-0205
A Phase II Study of Cabozantinib (XL184) in Patients With Advanced/Metastatic Urothelial Carcinoma
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
12-C-0118
A Phase II Study of Sunitinib in Patients with Advanced Relapsed or Refractory Thymoma or Thymic Carcinoma with at Least One Prior Line of Platinum-Based Systemic Chemotherapy
No longer recruiting/follow-up only
18-100 Years
NCI
Advanced
12-C-0112
Phase I Study of T Cells Expressing an Anti-CD19 Chimeric Receptor in Children and Young Adults with B Cell Malignancies
Completed Study; data analyses ongoing
1-30 Years
NCI
Advanced
12-C-0079
A Phase II Multicenter Study of AMG 386 and Abiraterone in Metastatic Castration Resistant Prostate Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
12-C-0066
Phase I Trial of Oral 5-Fluoro-2'-Deoxycytidine with Oral Tetrahydrouridine in Patients with Advanced Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
12-AR-8001
Compassionate Use Treatment Protocol I4V-MC-JAGA; Treatment of Autoinflammatory Syndromes Expected to Benefit from JAK Inhibition
Completed Study; data analyses ongoing
1-125 Years
NIAMS
Syndrome
11-N-0084
Evaluation and Diagnosis of Potential Research Subjects with Traumatic Brain Injury (TBI)
Completed Study; data analyses ongoing
18-125 Years
NINDS
Syndrome
11-I-0187
The Natural History and Pathogenesis of Human Fungal Infections
Participants currently recruited/enrolled
0-99 Years
NIAID
Syndrome
11-E-0072
Environmental Risk Factors for the Anti-Synthetase Syndrome
Participants currently recruited/enrolled
2-100 Years
NIEHS
Syndrome
11-D-0172
The Pathogenesis and Natural History of Sjogren's Syndrome
Participants currently recruited/enrolled
16-125 Years
NIDCR
Syndrome
11-CC-0152
The Natural History of Liver Disease in a Cohort of Participants with Hepatitis B and/or Hepatitis C with or without HIV Infection
Completed Study; data analyses ongoing
18-99 Years
CC
Syndrome
11-CC-0088
Effect of Aerobic Exercise Training on Cardiorespiratory Fitness in Patients with Traumatic Brain Injury
Completed Study; data analyses ongoing
21-45 Years
CC
Sleep
11-C-0255
Clinical, Epidemiologic, and Genetic Studies of Li-Fraumeni Syndrome
Participants currently recruited/enrolled
0-125 Years
NCI
Syndrome
11-C-0242
Collection of Blood from Patients with Cancer, Other Tumors, or Tumor Predisposition Syndromes for Analysis of Genetic Differences in Drug Disposition
Participants currently recruited/enrolled
3-125 Years
NCI
Syndrome
11-C-0220
Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS) Incorporating Pilot Evaluation of KSHV Targeted Therapies
Participants currently recruited/enrolled
18-125 Years
NCI
Syndrome
11-C-0200
A Phase II Trial In Which Patients With Metastatic Alveolar Soft Part Sarcoma Are Randomized to Either Sunitinib or Cediranib Monotherapy, with Cross-Over at Disease Progression
No longer recruiting/follow-up only
16-125 Years
NCI
Advanced
11-C-0140
A Phase I Study of Gemcitabine, Carboplatin and Lenalidomide (GCL) for Treatment of Patients with Advanced/Metastatic Urothelial Carcinoma (UC) and Other Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
11-C-0136
Multi-Institutional Prospective Pilot Study of Lupron to Enhance Lymphocyte Immune Reconstitution Following Allogeneic Bone Marrow Transplantation in Post-Pubertal Children and Adults with Molecular Imaging Evaluation
Completed Study; data analyses ongoing
2-55 Years
NCI
Syndrome
11-C-0096
Pilot Trial of Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies
No longer recruiting/follow-up only
18-125 Years
NCI
Advanced
11-C-0061
Phase I Trial of Z-Endoxifen in Adults with Refractory Hormone Receptor-Positive Breast Cancer, Desmoid Tumors, Gynecologic Tumors, or other Hormone Receptor-Positive Solid Tumors
No longer recruiting/follow-up only
18-125 Years
NCI
Advanced
11-C-0034
DICER1-Related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study
Participants currently recruited/enrolled
0-125 Years
NCI
Syndrome
10-N-0009
Physiological Investigations of Movement Disorders
Completed Study; data analyses ongoing
18-125 Years
NINDS
Syndrome
10-M-0112
Defining the Brain Phenotype of Children with Williams Syndrome
Participants currently recruited/enrolled
5-125 Years
NIMH
Syndrome
10-I-0197
Admission and Management of Occupational or Other Exposures to Biodefense/Bioterrorism Agents or to Epidemic/Emerging Infectious Diseases
Participants currently recruited/enrolled
2-99 Years
NIAID
Syndrome
10-H-0154
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused with a Reduced Dose of Non-Mobilized Donor T-Cells
Participants currently recruited/enrolled
4-80 Years
NHLBI
Syndrome
10-H-0126
Cardiovascular Disease Discovery Protocol
Participants currently recruited/enrolled
1-100 Years
NHLBI
Syndrome
10-E-0129
Study of the Effect of Innate Immunity on the Inflammatory Response to Endotoxin
Participants currently recruited/enrolled
18-125 Years
NIEHS
Syndrome
10-C-0114
A Phase II Study of Bevacizumab and Erlotinib in Subjects with Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
10-C-0066
A Study of Hairy Cell and other Leukemias with a Focus on Recombinant Immunotoxins for Cancer Treatment
Participants currently recruited/enrolled
18-125 Years
NCI
Syndrome
10-C-0056
A Phase I Study of Indenoisoquinolines LMP400 and LMP776 in Adults With Relapsed Solid Tumors and Lymphomas
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
09-N-0039
A Phase I Study of the Intrathecal Administration of Resiniferatoxin for Treating Severe Refractory Pain Associated with Advanced Cancer
Participants currently recruited/enrolled
18-125 Years
NINDS
Advanced
09-N-0010
Biomarkers of Risk of Parkinson Disease
Completed Study; data analyses ongoing
18-70 Years
NINDS
Sleep
09-I-0200
A Phase I Study of MozobilTM in the Treatment of Patients with WHIMS
Participants currently recruited/enrolled
18-75 Years
NIAID
Syndrome
09-I-0184
Studies in the Pathogenesis of Systemic Capillary Leak Syndrome
Participants currently recruited/enrolled
0-125 Years
NIAID
Syndrome
09-I-0126
Pathogenesis and Genetic Basis of Physical Induced Urticarial Syndromes
Participants currently recruited/enrolled
2-90 Years
NIAID
Syndrome
09-I-0102
Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ Lymphocytopenia
Participants currently recruited/enrolled
18-125 Years
NIAID
Syndrome
09-H-0199
A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R agonist), Eltrombopag, in Patients with Low to Int-2 Risk Myelodysplastic Syndrome (MDS)
Completed Study; data analyses ongoing
18-125 Years
NHLBI
Syndrome
09-DK-0223
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy
Participants currently recruited/enrolled
18-125 Years
NIDDK
Syndrome
09-CC-0217
Vasti Control of Patellofemoral Kinematics in Asymptomatic Volunteers
Completed Study; data analyses ongoing
18-55 Years
CC
Syndrome
09-C-0192
Phase II Study of Cediranib (AZD2171) in Patients With Alveolar Soft Part Sarcoma
No longer recruiting/follow-up only
0-125 Years
NCI
Advanced
09-C-0019
A Phase I Study of Dasatinib in Combination with Bevacizumab in Advanced Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Advanced
08-HG-0059
Studies of Skin Microflora in Healthy Individuals and Atopic Dermatitis Patients
Participants currently recruited/enrolled
2-125 Years
NHGRI
Syndrome
08-H-0046
Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive Therapy
Completed Study; data analyses ongoing
4-75 Years
NHLBI
Syndrome
08-DK-0173
A Trial of Segmental Stiffening Wires to Improve the Efficiency and Patient Tolerability of Colonoscopy
Completed Study; data analyses ongoing
40-80 Years
NIDDK
Advanced
08-DK-0138
A New Method for Determining Gastric Acid Output Using a Wireless Capsule
Completed Study; data analyses ongoing
18-125 Years
NIDDK
Syndrome
07-M-0021
Development of Functional and Structural Magnetic Resonance Imaging Techniques for the Study of Mood and Anxiety Disorders
Participants currently recruited/enrolled
18-65 Years
NIMH
Sleep
07-H-0142
Research Respiratory Tract Procedures
Participants currently recruited/enrolled
10-125 Years
NHLBI
Advanced
07-DK-0077
Study of the Phenotype of Overweight and Obese Adults
Participants currently recruited/enrolled
18-100 Years
NIDDK
Sleep
07-D-0016
Effects of PTH Replacement on Bone in Hypoparathyroidism
Completed Study; data analyses ongoing
18-70 Years
NIDCR
Syndrome
07-CH-0008
Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion
Completed Study; data analyses ongoing
18-85 Years
NICHD
Syndrome
06-M-0214
PET Measurement of Regional Rates of Cerebral Protein Synthesis in Subjects with Fragile X Syndrome
Completed Study; data analyses ongoing
18-24 Years
NIMH
Syndrome
06-I-0015
Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death
Participants currently recruited/enrolled
0-125 Years
NIAID
Syndrome
06-C-0213
Tissue Procurement Protocol for the Developmental Therapeutics Clinic, National Cancer Institute (NCI)
Participants currently recruited/enrolled
0-125 Years
NCI
Syndrome
05-CH-0037
The Effects of Hydrocortisone, Melatonin, and Placebo on Symptoms of Jet Lag
Completed Study; data analyses ongoing
18-65 Years
NICHD
Sleep
05-CC-0041
Endothelial Cell Dysfunction in Pulmonary Arterial Hypertension: Biomarkers, Mechanisms of Disease and Novel Therapeutic Targets
Completed Study; data analyses ongoing
18-125 Years
CC
Advanced
05-C-0152
Variation in Gene Expression in Neurofibromatosis Type 1
Completed Study; data analyses ongoing
2-100 Years
NCI
Syndrome
04-I-0286
A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease Progression
Participants currently recruited/enrolled
1-100 Years
NIAID
Syndrome
04-HG-0211
Analysis of Specimens from Individuals with Pulmonary Fibrosis
Participants currently recruited/enrolled
18-125 Years
NHGRI
Syndrome
04-H-0161
Studies of the Natural History of Sickle Cell Disease
Participants currently recruited/enrolled
2-125 Years
NHLBI
Syndrome
04-CC-0119
Biomarkers and Protein Mass Expression Profiles in Bronchoalveolar Lavage from Patients with Lung Infiltrates
Participants currently recruited/enrolled
3-99 Years
CC
Advanced
04-C-0238
A Phase 2 Study of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Von Hippel Lindau Disease and Renal Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Syndrome
04-C-0102
Hematologic Malignancy Biology Study
Enrolling by Invitation
1-75 Years
NCI
Syndrome
04-AR-0205
Progression of Spinal Fusion in Ankylosing Spondylitis
Completed Study; data analyses ongoing
18-125 Years
NIAMS
Advanced
03-DA-N380
Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging
Participants currently recruited/enrolled
18-80 Years
NIDA
Advanced
03-CC-0060
Virtual Function Anatomy (VFA)
Participants currently recruited/enrolled
5-95 Years
CC
Syndrome
03-C-0278
A Comparative Study of Pediatric CNS Tumor Activity as Assessed by 18F-FDG PET Imaging and Proton Magnetic Resonance Spectroscopic Imaging (1H-MRSI)
Completed Study; data analyses ongoing
1-21 Years
NCI
Sleep
03-AR-0173
Studies of Natural History, Pathogenesis, and Outcomes in Autoimmune and Inflammatory Diseases Including Juvenile Dermatomyositis
Participants currently recruited/enrolled
2-125 Years
NIAMS
Syndrome
02-I-0286
Efficacy of Tyrosine Kinase Inhibition in Reducing Eosinophilia in Patients with Myeloid and/or Steroid-Refractory Hypereosinophilic Syndrome
Participants currently recruited/enrolled
2-125 Years
NIAID
Syndrome
02-CH-0311
Investigations into Inborn Errors of Cholesterol Synthesis and Related Disorders
Participants currently recruited/enrolled
0-125 Years
NICHD
Syndrome
02-C-0212
Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer
Completed Study; data analyses ongoing
18-100 Years
NCI
Syndrome
02-C-0211
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Melanoma
Participants currently recruited/enrolled
2-125 Years
NCI
Syndrome
02-C-0159
Birt-Hogg-Dub(SqrRoot)(Copyright) Syndrome: Characterization of the FLCN Disease Gene and Predisposition to Renal Cancer, Cutaneous Fibrofolliculoma and Pulmonary Cysts
Participants currently recruited/enrolled
2-125 Years
NCI
Syndrome
02-C-0052
Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History Study
Participants currently recruited/enrolled
0-125 Years
NCI
Syndrome
01-I-0202
Natural History, Genetics, Phenotype, and Treatment of Mycobacterial Infections
Participants currently recruited/enrolled
0-100 Years
NIAID
Syndrome
01-DC-0228
Clinical and Molecular Analysis of Enlarged Vestibular Aqueducts
Completed Study; data analyses ongoing
0-99 Years
NIDCD
Syndrome
00-I-0159
Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)
Participants currently recruited/enrolled
0-125 Years
NIAID
Syndrome
00-HG-0209
Molecular and Clinical Studies of Primary Immunodeficiency Diseases
No longer recruiting/follow-up only
3-125 Years
NHGRI
Syndrome
00-HG-0153
Investigations into Chediak-Higashi Syndrome and Related Disorders
Participants currently recruited/enrolled
0-70 Years
NHGRI
Syndrome
00-H-0051
Cutaneous Tumorigenesis in Patients with Tuberous Sclerosis
Participants currently recruited/enrolled
18-90 Years
NHLBI
Syndrome
00-CH-0160
Clinical and Molecular Analysis of ACTH-Independent Steroid Hormone Production in Adrenocortical Tissue
Completed Study; data analyses ongoing
3-70 Years
NICHD
Syndrome
99-H-0050
Non-Myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematologic Malignancies in High Risk Patients and in Patients with Debilitating Hematologic Diseases
Completed Study; data analyses ongoing
2-80 Years
NHLBI
Syndrome
99-C-0099
Examination of Clinical and Laboratory Abnormalities in Patients with Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy
Participants currently recruited/enrolled
0-125 Years
NCI
Syndrome
98-D-0145
Screening and Natural History of Patients with Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome
Participants currently recruited/enrolled
0-100 Years
NIDCR
Syndrome
98-CH-0081
Clinical and Basic Investigations into Smith-Lemli-Opitz Syndrome
Completed Study; data analyses ongoing
0-125 Years
NICHD
Syndrome
97-HG-0192
Genetic Studies in the Amish and Mennonites
Completed Study; data analyses ongoing
18-125 Years
NHGRI
Syndrome
97-C-0147
Collection of Serum and Tissue Samples from Patients with Biopsy-Proved or Suspected Malignant Diseases
Participants currently recruited/enrolled
2-125 Years
NCI
Syndrome
96-I-0052
A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients with Suspected Post Treatment Lyme Disease Syndrome and Selected Control Populations
Participants currently recruited/enrolled
13-125 Years
NIAID
Syndrome
95-HG-0193
Clinical and Basic Investigations into Hermansky-Pudlak Syndrome
Participants currently recruited/enrolled
0-125 Years
NHGRI
Syndrome
95-CH-0059
Definition of the Genotype and Clinical Phenotype of Primary Pigmented Nodular Adrenocortical Disease (PPNAD), Carney Complex, Peutz-Jeghers Syndrome and Related Conditions
Completed Study; data analyses ongoing
3-70 Years
NICHD
Syndrome
94-HG-0132
The Phenotype and Etiology of Proteus Syndrome
Participants currently recruited/enrolled
0-125 Years
NHGRI
Syndrome
94-HG-0105
An Exploratory Study of the Genetics, Pathophysiology, and Natural History of Autoinflammatory Diseases
Participants currently recruited/enrolled
0-125 Years
NHGRI
Syndrome
93-I-0086
Evaluation and Long-Term Follow-Up of Patients with Acute or Chronic Inflammatory Disorders
Enrolling by Invitation
2-125 Years
NIAID
Syndrome
93-I-0063
Study of the Immunopathogenesis, Natural History, and Genetics of Autoimmune Lymphoproliferative Syndrome (ALPS) Associated with an Expansion of CD4-8-/TCR alpha/beta+ T Cells
Participants currently recruited/enrolled
0-99 Years
NIAID
Syndrome
92-I-0125
A Study of Viral Burden in Peripheral Blood Versus Lymphoid and Bone Marrow Tissue in HIV-Infected Individuals
Participants currently recruited/enrolled
18-125 Years
NIAID
Advanced
92-DK-0156
Studies of Immunologically-Mediated Kidney Diseases
Participants currently recruited/enrolled
10-125 Years
NIDDK
Syndrome
90-M-0088
The Treatment of Menstrually-Related Mood Disorders with the Gonadotropin Releasing Hormone (GnRH) Agonist, Depot Leuprolide Acetate (Lupron)
Completed Study; data analyses ongoing
18-45 Years
NIMH
Syndrome
90-DK-0137
Evaluation of the Gastrinoma in Patients with Zollinger-Ellison Syndrome
Completed Study; data analyses ongoing
18-100 Years
NIDDK
Syndrome
89-M-0006
Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers
Participants currently recruited/enrolled
3-125 Years
NIMH
Syndrome
89-I-0158
Studies of Immune Regulation in Patients with Common Variable Immunodeficiency and Related Humoral Immunodeficiency Syndromes
Participants currently recruited/enrolled
2-125 Years
NIAID
Syndrome
81-M-0126
The Evaluation of Women with Menstrually Regulated Mood and Behavioral Disorders
Participants currently recruited/enrolled
18-50 Years
NIMH
Syndrome