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593 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number Title Protocol Status Min-Max Age Institute Keywords
20-C-0011Phase 1 Study of Recombinant Human IL-15 (rhIL-15) and Mogamulizumab for Patients with Refractory or Relapsed Adult T-Cell Leukemia and Mycosis Fungoides/Sezary SyndromeCompleted Study; data analyses ongoing18-125 YearsNCI Adult T-Cell Leukemia/lymphoma
12-C-0193Lymphoid Malignancies and Precursors: Tissue Acquisition ProtocolParticipants currently recruited/enrolled18-125 YearsNCI Adult T-Cell Leukemia/lymphoma
09-C-0025Phase II Trial of LMB-2, Fludarabine and Cyclophosphamide for Adult T-Cell LeukemiaNo longer recruiting/follow-up only18-125 YearsNCI Adult T-Cell Leukemia/lymphoma
000792-CA Multicenter Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults with B Lineage Acute LymphoblaRecruitment has not started1-25 YearsNCI Adult T-Cell
000631-CInvestigation of the Cognitive Aftereffects of Neurotoxicity in Children and Young Adults with Relapsed/Refractory Hematologic Malignancies who Receive CAR T-cell TherapyRecruitment has not started5-125 YearsNCI Adult T-Cell
000324-CPhase 1/2 Dose Escalation Study of CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults with Recurrent or Refractory CD19/CD22-expressing B Cell MalignanciesParticipants currently recruited/enrolled3-35 YearsNCI Adult T-Cell
20-C-0103Investigation of the B- and T-cell Repertoire and Immune Response in Patients with Acute and Resolved COVID-19 InfectionParticipants currently recruited/enrolled18-125 YearsNCI Adult T-Cell
20-C-0098A Phase 1/2, Open Label, Dose-Escalation, Safety and Tolerability Study of NC410 in Subjects with Advanced or Metastatic Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Adult T-Cell
20-C-0041Protocol for a Research Database for Hematopoietic Cell Transplantation, Other Cellular Therapies and Marrow Toxic InjuriesEnrolling by Invitation1-125 YearsNCI Adult T-Cell
19-I-0015Phase 1/2 Randomized, Double-Blind, Placebo-Controlled Study of Safety and Efficacy of Abatacept for Treating Chronic Cytopenia in Cytotoxic T-lymphocyte Antigen 4 (CTLA4) HaploinsufficiencyParticipants currently recruited/enrolled8-65 YearsNIAIDAdult T-Cell
19-C-0117A Phase 1 / 2 Single Arm Open-label Clinical Trial of Gavocabtagene Autoleucel (gavo-cel) in Patients with Advanced Mesothelin Expressing CancerParticipants currently recruited/enrolled18-120 YearsNCI Adult T-Cell
19-C-0017A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced with a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 PatientsParticipants currently recruited/enrolled18-70 YearsNCI Adult T-Cell
18-I-0041Investigating the Mechanistic Biology of Primary Immunodeficiency DisordersParticipants currently recruited/enrolled0-75 YearsNIAIDAdult T-Cell
17-C-0113A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced with a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 PatientsParticipants currently recruited/enrolled18-70 YearsNCI Adult T-Cell
16-N-0072A Pilot Study of Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy with Ex Vivo Generated Polyomavirus-Specific T-cellsCompleted Study; data analyses ongoing18-125 YearsNINDSAdult T-Cell
16-C-0131A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced with a CD70-Binding Chimeric Antigen Receptor to Patients with CD70-Expressing CancersParticipants currently recruited/enrolled18-70 YearsNCI Adult T-Cell
16-C-0062A Phase I Study of Subcutaneous Recombinant Human IL-15 (S.C. Rhil-15) and Alemtuzumab for Patients with Refractory or Relapsed Chronic and Acute Adult T-Cell Leukemia (ATL)Completed Study; data analyses ongoing18-125 YearsNCI Adult T-Cell
16-C-0061Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy ProtocolsParticipants currently recruited/enrolled18-125 YearsNCI Adult T-Cell
13-C-0006Phase I/II Trial Evaluating the Safety and Efficacy of Ruxolitinib in Patients with Smoldering and Chronic Adult T-cell Leukemia (ATL)Completed Study; data analyses ongoing18-125 YearsNCI Adult T-Cell
02-C-0179Biospecimen Acquisition from Human SubjectsParticipants currently recruited/enrolled18-125 YearsNCI Adult T-Cell
001516-CPhase I Study of Aerosolized Antibiotics and Pembrolizumab in Advanced Non-Small Cell Lung CancerRecruitment has not started10-120 YearsNCI Adult
001125-DKOptimizing HBV Care Cascade among Foreign-Born in the United States (FOCUS-HBV Study)Participants currently recruited/enrolled18-100 YearsNIDDKAdult
001124-IExpanded Access IND Protocol: Use of Tecovirimat (TPOXX (R)) for Treatment of Human Non-Variola Orthopoxvirus Infections in Adults and ChildrenEnrolling by Invitation0-125 YearsNIAIDAdult
001109-CDefining the Natural History of Squamous Cell Carcinoma in Fanconi AnemiaParticipants currently recruited/enrolled8-125 YearsNCI Adult
001056-CLongitudinal Early Advance Care Planning Discussions and Documentation (LEADD) Program: An Exploratory Study in Adolescents and Young Adults (AYAs) Receiving Hematopoietic Stem Cell TransplantParticipants currently recruited/enrolled18-125 YearsNCI Adult
001032-CBAY 1895344 Plus Topoisomerase-1 (Top1) Inhibitors in Patients with Advanced Solid Tumors, Phase I Studies with Expansion Cohorts in Small Cell Lung Carcinoma (SCLC), Poorly Differentiated Neuroendocrine Carcinoma (PD-NEC) and Pancreatic Adenocarcinoma (Recruitment has not started18-125 YearsNCI Adult
001018-CHEstablishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type CParticipants currently recruited/enrolled0-125 YearsNICHDAdult
001004-CA Phase 1b/2 Basket Study of ACR-368 as Monotherapy and in Combination with Gemcitabine in Adult Subjects with Platinum-Resistant Ovarian Carcinoma, Endometrial Adenocarcinoma, and Urothelial Carcinoma Based on Acrivon Oncosignature (R) StatusParticipants currently recruited/enrolled18-120 YearsNCI Adult
000889-IVRC 615: A Phase I, Open-Label, Dose-Escalation Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIVMAB-0115-AB (VRC01.23LS), Administered Intravenously or Subcutaneously to Healthy AdultsParticipants currently recruited/enrolled18-60 YearsNIAIDAdult
000871-CCMediterranean-like Unprocessed (CLEAN-MED) Diet Intervention Study of the Gut Microbiome of Healthy AdultsParticipants currently recruited/enrolled18-60 YearsCC Adult
000866-IPhase 1/2 Open-label Trial of Safety and Zoster Immunogenicity Evaluation for people with HIV with CD4 counts Under and Above 300 following Shingrix Vaccination (ZEUS)Participants currently recruited/enrolled18-125 YearsNIAIDAdult
000865-NNatural History Protocol for Movement DisordersParticipants currently recruited/enrolled2-125 YearsNINDSAdult
000849-CHSpeckle Plethysmography Pulse Transit Time as a Marker of Blood Pressure ChangesRecruitment has not started18-125 YearsNICHDAdult
000829-HControls and Healthy Vasculature InitiativeParticipants currently recruited/enrolled18-125 YearsNHLBIAdult
000827-ARNatural History and Pathogenesis of Alopecia in Children and AdultsParticipants currently recruited/enrolled2-45 YearsNIAMSAdult
000824-M[11C]-(R)-Rolipram to Measure cAMP Signaling Before and After KetamineEnrolling by Invitation18-70 YearsNIMH Adult
000821-IAn Open-Label, Single-Arm, Phase 1/2 Dose-Escalation Trial of Long-Acting Recombinant Human IL-7 (NT-I7, Efineptakin Alfa) for Idiopathic CD4 LymphopeniaRecruitment has not started18-75 YearsNIAIDT-Cell
000798-DA Phase 2 Study of Burosumab for Fibroblast Growth Factor-23 Mediated Hypophosphatemia in Fibrous DysplasiaParticipants currently recruited/enrolled1-125 YearsNIDCRAdult
000784-NAssessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human SubjectsParticipants currently recruited/enrolled18-125 YearsNINDSAdult
000780-DA Phase 2 Study of Denosumab for Prevention of Skeletal Disease Progression in Children with Fibrous DysplasiaParticipants currently recruited/enrolled4-14 YearsNIDCRAdult
000776-MAn Open Trial of Transcranial Magnetic Stimulation for Youth with Treatment-Resistant Major Depressive DisorderRecruitment has not started13-17 YearsNIMH Adult
000756-DKPhase II Study of Growth Hormone Inhibition Using Pegvisomant In Severe Insulin ResistanceParticipants currently recruited/enrolled18-65 YearsNIDDKAdult
000731-CA First-In-Human, Open-Label, Multicenter Study of VOR33 in Patients with Acute Myeloid Leukemia who are at High-Risk for Leukemia Relapse following Hematopoietic Cell TransplantationParticipants currently recruited/enrolled18-70 YearsNCI Adult
000711-NImmunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2 (IN-PASC)Enrolling by Invitation18-125 YearsNINDSAdult
000696-CA Phase III, Multicenter, International Study with a Parallel, Randomized, Double-blind, Placebo-controlled, 2 Arm Design to Assess the Efficacy and Safety of Selumetinib in Adult Participants with NF1 who have Symptomatic, Inoperable Plexiform NeurofibrParticipants currently recruited/enrolled18-120 YearsNCI Adult
000688-ILongitudinal Observations of Vaccine Responses to SARS-CoV-2 and other Emerging Infectious DiseasesParticipants currently recruited/enrolled18-125 YearsNIAIDAdult
000687-IVRC 322/DMID 21-0016: A Phase I, Dose Escalation, Open-Label Clinical Trial to Evaluate Safety, Tolerability and Immunogenicity of a Nipah Virus (NiV) mRNA Vaccine, mRNA-1215, in Healthy AdultsParticipants currently recruited/enrolled18-60 YearsNIAIDAdult
000686-CHIntrathecal 2-Hydroxypropyl-Beta-Cyclodextrin for Neurological Decline in Patients with Niemann-Pick Disease Type C1Participants currently recruited/enrolled18-125 YearsNICHDAdult
000676-M[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PETParticipants currently recruited/enrolled18-70 YearsNIMH Adult
000674-MAssessment of [18F]SF12051 for Imaging the 18-kDa Translocator Protein (TSPO) in Brain and Whole Body of Healthy SubjectsParticipants currently recruited/enrolled18-99 YearsNIMH Adult
000661-CComprehensive Molecular and Clinical Evaluation of Pediatric and Adult Myelodysplastic Syndromes (MDS)Participants currently recruited/enrolled0-125 YearsNCI Adult
000647-CAn Open-label, Multicenter Follow-up Study to Collect Long-term Data on Participants from Multiple Bintrafusp alfa (M7824) Clinical StudiesRecruitment has not started18-125 YearsNCI Adult
000633-CPhase 1/2 Study of VIP152, Venetoclax, and Prednisone (VVIP) in Relapsed/Refractory Lymphoid MalignanciesParticipants currently recruited/enrolled18-125 YearsNCI T-Cell
000625-NInvestigational use of Neuromuscular UltrasoundParticipants currently recruited/enrolled18-125 YearsNINDSAdult
000617-DKA Natural History Study of Metabolic Sizing in Health and DiseaseParticipants currently recruited/enrolled10-125 YearsNIDDKAdult
000612-CPhase 1 Study of NT-I7 (rhIL-7-hyFc) for the Treatment of Kaposi Sarcoma in Patients With or Without Infection with HIVParticipants currently recruited/enrolled18-125 YearsNCI Adult
000545-DKPrevalence and Development of Liver Dysfunction in Hematopoietic Stem Cell Transplant: A Prospective Natural History StudyRecruitment has not started3-125 YearsNIDDKAdult
000536-IVRC 614: A Phase 1, Dose Escalation, Open-Label Clinical Trial with Experimental Controlled Human Malaria Infections (CHMI) to Evaluate Safety and Protective Efficacy of an Anti-Malaria Human Monoclonal Antibody, VRC-MALMAB0114-00-AB (L9LS), in Healthy MNo longer recruiting/follow-up only18-50 YearsNIAIDAdult
000527-MCNS Correlates of Extended Sleep RestrictionParticipants currently recruited/enrolled18-39 YearsNIMH Adult
000520-CPhase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG with or without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung CancerRecruitment has not started18-125 YearsNCI Adult
000519-EIPhase II, Multicenter, Open-label Safety Study of Bilateral NT-501 in Participants with Macular Telangiectasia Type 2No longer recruiting/follow-up only18-125 YearsNEI Adult
000518-CCObservational Study of Dietary Intake and Dietary Behaviors in Adults with Sickle Cell DiseaseParticipants currently recruited/enrolled18-125 YearsCC Adult
000509-CAn Open Label, Multi-Center Roll-Over Study to Assess Long-Term Safety in Patients Who are Ongoing or Have Completed a Prior Global Novartis or GSK Sponsored Tafinlar (Dabrafenib) and/or Mekinist (Trametinib) Study and are Judged by the Investigator to BEnrolling by Invitation18-125 YearsNCI Adult
000491-CTissue Procurement and Natural History Study of Neuroendocrine Neoplasms (NENs) Including Adrenocortical Carcinoma (ACC)Participants currently recruited/enrolled18-125 YearsNCI Adult
000489-CPhase I/II Study Using Prophylactic Donor Lymphocyte Infusion Early Post-Transplant After Allogeneic Hematopoietic Cell Transplantation Using Post-Transplantation Cyclophosphamide for High-Risk Hematologic MalignanciesClinical hold/Recruitment or enrollment suspended12-125 YearsNCI Adult
000486-CA Phase 1 Trial of the ATR Inhibitor BAY 1895344 in Combination with Cisplatin and with Cisplatin Plus Gemcitabine in Advanced Solid Tumors with an Emphasis on Urothelial CarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Adult
000484-CRandomized Phase II Trial of Durvalumab (D) plus Olaparib (O) and Cediranib (C: DOC) Compared to OC or DC or Chemotherapy in Platinum-Resistant Recurrent Ovarian Cancer with Prior BevacizumabParticipants currently recruited/enrolled18-125 YearsNCI Adult
000479-HObservational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative TherapiesParticipants currently recruited/enrolled18-125 YearsNHLBIAdult
000475-CPhase 2 Study of Rogaratinib (BAY 1163877) in the Treatment of Patients with Sarcoma Harboring Alterations in Fibroblast Growth Factor Receptor (FGFR) 1-4 and SDH-deficient Gastrointestinal Stromal Tumor (GIST)Participants currently recruited/enrolled18-125 YearsNCI Adult
000462-CPhase 2, Open-label, Single-arm, Window of Opportunity Study of ASP-1929 Photoimmunotherapy with Fluorescence Imaging in Patients With Operable Primary or Recurrent Head and Neck or Cutaneous Squamous Cell CarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Adult
000444-HVaccine Responses in Patients with B Cell MalignanciesParticipants currently recruited/enrolled18-125 YearsNHLBIAdult
000428-NAn Observational Study to Assess Clinical, Molecular and Imaging Biomarkers in Spinal and Bulbar Muscular Atrophy (SBMA)Participants currently recruited/enrolled18-125 YearsNINDSAdult
000423-CFeasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults with Sickle Cell Disease (SCD): A Pilot Randomized Controlled TrialParticipants currently recruited/enrolled18-55 YearsNCI Adult
000413-HNatural History study of CADASILParticipants currently recruited/enrolled18-100 YearsNHLBIAdult
000411-CCA Feasibility Pilot Study of a Virtual Education-Based Transition Intervention to Improve Transition Readiness in Adolescent and Young Adults with Congenital Adrenal Hyperplasia.Recruitment has not started16-22 YearsCC Adult
000410-IVRC 325 (000410): A Phase I Open-Label Clinical Trial to Evaluate the Dose, Safety, Tolerability and Immunogenicity of Mosaic Quadrivalent Influenza Vaccine with and without Adjuplex Compared with a Licensed Inactivated Seasonal QIV, In Healthy AdultsParticipants currently recruited/enrolled18-50 YearsNIAIDAdult
000406-AAAddictions Neuroclinical AssessmentEnrolling by Invitation18-125 YearsNIAAAAdult
000392-IMetabolic Profiling of Immune Responses in Immune-Mediated DiseasesParticipants currently recruited/enrolled18-75 YearsNIAIDAdult
000378-MIdentifying decision making parameters in healthy volunteers (HV) and anxiety patients (AD)Completed Study; data analyses ongoing18-50 YearsNIMH Adult
000359-CPhase I/II study to reduce post-transplantation cyclophosphamide dosing for older or unfit patients undergoing bone marrow transplantation for hematologic malignanciesParticipants currently recruited/enrolled12-85 YearsNCI Adult
000356-CA Phase I/II Trial of BMS-986253 in Myelodysplastic SyndromesParticipants currently recruited/enrolled18-125 YearsNCI Adult
000354-CPhase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell CarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Adult
000344-DKNatural History Study of Parathyroid DisordersParticipants currently recruited/enrolled0-125 YearsNIDDKAdult
000331-IInvestigating the Human Immune Response to Ixodes scapularis Tick BitesParticipants currently recruited/enrolled18-99 YearsNIAIDAdult
000326-HA Phase 1, Dose Escalation, Safety and Tolerability Study of NX- 2127, a Bruton's Tyrosine Kinase (BTK) Degrader, in Adults with Relapsed/Refractory B-cell MalignanciesParticipants currently recruited/enrolled18-125 YearsNHLBIAdult
000320-IRandomized, Double-Blinded, Placebo-Controlled, Phase 1 Study of the Safety and Immunogenicity of BPL-1357, A BPL-Inactivated, Whole-Virus, Universal Influenza VaccineParticipants currently recruited/enrolled18-55 YearsNIAIDAdult
000302-CA Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract MalignanciesParticipants currently recruited/enrolled18-125 YearsNCI Adult
000297-CHA Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Crinecerfont (NBI-74788) in Adult Subjects with Classic Congenital Adrenal Hyperplasia, Followed by Open-Label TreatmentParticipants currently recruited/enrolled18-125 YearsNICHDAdult
000293-CManaging Cancer and Living Meaningfully (CALM) Therapy in Individuals Diagnosed with a Primary Central Nervous System TumorEnrolling by Invitation18-125 YearsNCI Adult
000291-IObservational Digital Biomarker Discovery in Respiratory Virus Challenge StudiesRecruitment has not started18-65 YearsNIAIDAdult
000288-CA Phase II, Open-Label, Single-Arm Study of Berzosertib (M6620) in Combination with Topotecan in Participants with Relapsed Platinum-Resistant Small-Cell Lung CancerCompleted Study; data analyses ongoing18-125 YearsNCI Adult
000277-CImaging and Biopsy of HIV-Infected Individuals Undergoing Analytic Treatment InterruptionParticipants currently recruited/enrolled18-125 YearsNCI Adult
000274-CPhase I Trial of Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated LymphomasParticipants currently recruited/enrolled18-125 YearsNCI Adult
000272-HDefining the Genetic Etiology of Suppurative Lung Disease in Children and AdultsParticipants currently recruited/enrolled5-45 YearsNHLBIAdult
000264-CA Pharmacodynamics-Driven Trial of Talazoparib, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Aberrations in Genes Involved in DNA Damage ResponseParticipants currently recruited/enrolled18-125 YearsNCI Adult
000261-AAMechanisms Underlying Individual Variations of Taste and Smell in ObesityParticipants currently recruited/enrolled18-65 YearsNIAAAAdult
000256-INatural History of Systemic and Nasal Mucosal Immunity to Influenza and SARS-CoV-2 in Adults after VaccinationParticipants currently recruited/enrolled18-125 YearsNIAIDAdult
000254-CA Phase II Trial of the Superenhancer Inhibitor Minnelide in Advanced Refractory Adenosquamous Carcinoma of the Pancreas (ASCP)Participants currently recruited/enrolled18-125 YearsNCI Adult
000251-CThe Effect of Diet and Exercise on ImmuNotherapy and the Microbiome (EDEN)Participants currently recruited/enrolled18-125 YearsNCI Adult
000247-DKEvaluation of Patients with Gastrointestinal DiseaseParticipants currently recruited/enrolled18-125 YearsNIDDKAdult
000237-CPhase II Study of Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis from Colorectal, Appendiceal, Small Bowel, Gastric, Ovarian, or Other Gynecologic Primary CancerParticipants currently recruited/enrolled18-125 YearsNCI Adult
000236-IA Phase 1 Study of Empagliflozin as Treatment for Severe Congenital Neutropenia Due to G6PC3 DeficiencyParticipants currently recruited/enrolled18-125 YearsNIAIDAdult
000235-CHCOLSIO Trial: Phase II Randomized, Controlled Trial of Colchicine to Suppress Inflammation and Improve Insulin Resistance in Adults and Adolescents with ObesityParticipants currently recruited/enrolled12-125 YearsNICHDAdult
000212-IInduced Blood-Stage Plasmodium Vivax Infection with HMPBS02-Pv Challenge Agent in Healthy Malaria-Naive Adults to Produce a Plasmodium Vivax Parasite Cell Bank for Future StudiesNo longer recruiting/follow-up only18-50 YearsNIAIDAdult
000207-ARThe Natural History of Coronavirus Disease (COVID-19) in Systemic Autoimmune Diseases; An Observational Prospective StudyParticipants currently recruited/enrolled15-125 YearsNIAMSAdult
000196-NTask-dependent Effects of TMS on the Neural Biomarkers of Episodic MemoryParticipants currently recruited/enrolled18-40 YearsNINDSAdult
000193-CPhase 1 Study of Copanlisib with Dose-adjusted EPOCH-R in Relapsed and Refractory Burkitt Lymphoma and other High-Grade B-cell LymphomasClinical hold/Recruitment or enrollment suspended18-125 YearsNCI T-Cell
000187-EIAdaptive Optics Imaging of Outer Retinal DiseasesParticipants currently recruited/enrolled21-125 YearsNEI Adult
000178-CHyperspectral Analysis of Sweat Metabolite Biometrics for Real-Time Detection of COVID-19Participants currently recruited/enrolled18-125 YearsNCI Adult
000176-CA Phase I/II Trial of Lurbinectedin with Berzosertib, an ATR Kinase Inhibitor in Small Cell Cancers and High Grade Neuroendocrine CancersParticipants currently recruited/enrolled18-125 YearsNCI Adult
000152-ENatural History of The Human Biological Response to Environmental Exposure and InjuryParticipants currently recruited/enrolled18-125 YearsNIEHSAdult
000141-DCDeep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic TargetsParticipants currently recruited/enrolled18-80 YearsNIDCDAdult
000134-IA Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Trial of Intravenous Zotatifin in Adults with Mild or Moderate Coronavirus Disease 2019 (COVID-19)Participants currently recruited/enrolled18-125 YearsNIAIDAdult
000130-DKUnraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research ApproachParticipants currently recruited/enrolled18-125 YearsNIDDKAdult
000126-NA Pilot Study of NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patients with Progressive Multifocal LeukoencephalopathyParticipants currently recruited/enrolled18-125 YearsNINDSAdult
000115-CA Trial of the Safety and Immunogenicity of the COVID-19 Vaccine (mRNA-1273) in Participants with Hematologic Malignancies and Various Regimens of Immunosuppression, and in Participants with Solid Tumors on PD1/PDL1 Inhibitor Therapy, Including Booster DParticipants currently recruited/enrolled18-125 YearsNCI Adult
000114-CA Phase II Study Evaluating T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination with the Immunocytokine M9241 in Localized High and Intermediate Risk Prostate Cancer Treated with Androgen Deprivation TherapyParticipants currently recruited/enrolled18-125 YearsNCI T-Cell
000110-HA Phase II Study Evaluating Fostamatinib for Hospitalized Adults with COVID-19Completed Study; data analyses ongoing18-125 YearsNHLBIAdult
000108-EIAn Observational Prospective Natural History Study of Stargardt-like Macular Dystrophy (STDG3) Secondary to Mutations in ELOVL4Participants currently recruited/enrolled10-125 YearsNEI Adult
000102-CCCOVID-19, Chronic Adaptation and Response to Exercise (COVID-CARE): A Randomized Controlled TrialParticipants currently recruited/enrolled18-80 YearsCC Adult
000101-MAn Investigation of the Antidepressant Effects of the mGlu2/3 receptor antagonist TS-161 in Treatment-Resistant DepressionParticipants currently recruited/enrolled18-65 YearsNIMH Adult
000096-CA Phase II study of Immunotherapy Combination: Irradiated PD-L1 CAR-NK cells plus Pembrolizumab plus N-803 for Subjects with Recurrent/Metastatic Gastric or Head and Neck CancerParticipants currently recruited/enrolled18-125 YearsNCI Adult
000092-CPhase 1/2 study of Vincristine and Temozolomide in Combination with PEN-866 for Adolescents and Young Adults with Relapsed or Refractory Solid TumorsRecruitment has not started12-39 YearsNCI Adult
000089-NNatural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of HealthParticipants currently recruited/enrolled18-125 YearsNINDSAdult
000085-CAssessing Sleep and Circadian Rhythms in Primary Brain Tumors Patients: An Observational StudyEnrolling by Invitation18-99 YearsNCI Adult
000081-CA Phase 2 Study of Anti-PD-L1 Antibody (Atezolizumab) in Chondrosarcoma and Clear Cell SarcomaCompleted Study; data analyses ongoing2-125 YearsNCI Adult
000080-C18F-DCFPyL PET/CT in Hepatocellular CarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Adult
000070-HGGenomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study(GENE-FORECAST): Sodium Intervention Trial (SIT)/GENE-FORECAST SITParticipants currently recruited/enrolled21-125 YearsNHGRIAdult
000067-CUnderstanding the Patient Experience: Symptom Burden in Pediatric Patients Receiving Chimeric Antigen Receptor (CAR) T-cell TherapyParticipants currently recruited/enrolled2-125 YearsNCI T-Cell
000064-IA Phase 1/2 Open-label Study to Evaluate the Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease with Inflammatory ComplicationsEnrolling by Invitation18-125 YearsNIAIDAdult
000059-CPhase I Study of Intratumor Injection of anti-Mesothelin Immunotoxin LMB-100 with Ipilimumab in Malignant MesotheliomaParticipants currently recruited/enrolled18-125 YearsNCI Adult
000057-CA Phase 1 Study of AZD8186 in Combination with Docetaxel in Patients with PTEN Mutated or PIK3CB Mutated Advanced Solid Tumors, Potentially Amenable to DocetaxelCompleted Study; data analyses ongoing18-125 YearsNCI Adult
000051-NNIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)Participants currently recruited/enrolled48-70 YearsNINDSAdult
000049-HEvaluation of the Safety,Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects with Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of MitapivatNo longer recruiting/follow-up only18-70 YearsNHLBIAdult
000048-CA Multi-Center Natural History Study of Precision-Based Genomics in Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI Adult
000045-CA Phase I Trial of T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and other KK-LC-1 Positive Epithelial CancersParticipants currently recruited/enrolled18-125 YearsNCI Adult
000036-AAA Phase I, Randomized, Double-Blind, Placebo-Controlled, Study of Safety, Tolerability, and Bioeffects of Alirocumab in Non-treatment Seeking Heavy DrinkersParticipants currently recruited/enrolled21-65 YearsNIAAAAdult
22-DK-0002Effect of Ultra-processed versus Unprocessed Diets on Energy MetabolismParticipants currently recruited/enrolled18-60 YearsNIDDKAdult
22-C-0003Feasibility of Evaluating Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral MicrodialysisParticipants currently recruited/enrolled18-39 YearsNCI Adult
21-N-0016Phase I/II Study of Teriflunomide in HTLV-1 Associated Myelopathy/Tropical Spastic ParaparesisParticipants currently recruited/enrolled18-125 YearsNINDSAdult
21-N-0010A Phase 2 Clinical Trial of Tolebrutinib, a Brain-penetrant Bruton's Tyrosine Kinase Inhibitor, for the Modulation of Chronically Inflamed White Matter Lesions in Multiple SclerosisNo longer recruiting/follow-up only18-125 YearsNINDSAdult
21-M-0031A Feasibility Study of Transcranial Electric Stimulation Therapy (TEST) for treatment resistant depression (TRD)Participants currently recruited/enrolled25-64 YearsNIMH Adult
21-I-0005Phase 1 Study of the Safety and Immunogenicity of an Epstein-Barr virus (EBV) gp350- Ferritin Nanoparticle Vaccine in Healthy Adults With or Without EBV InfectionParticipants currently recruited/enrolled18-29 YearsNIAIDAdult
21-HG-0020Caregiving Networks Across Disease Context and the Life Course: A Comparative Longitudinal StudyParticipants currently recruited/enrolled18-125 YearsNHGRIAdult
21-H-0027Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens into the Human LungParticipants currently recruited/enrolled18-64 YearsNHLBIAdult
21-CH-0028A Pilot Study to Evaluate a Noninvasive Multimodal Biosensing Device for Screening and Monitoring Response to Treatment of Infectious Respiratory Diseases.Participants currently recruited/enrolled18-125 YearsNICHDAdult
21-C-0030Phase I Study of GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Hepatocellular Carcinoma (HCC)Participants currently recruited/enrolled18-125 YearsNCI Adult
21-C-0023A Phase I Study of Pomalidomide and Nivolumab in Patients with Virus-Associated Malignancies With or Without HIVParticipants currently recruited/enrolled18-125 YearsNCI Adult
21-C-0019Phase I Study of Anti-CD22 Chimeric Receptor T Cells in Patients with Relapsed/Refractory Hairy Cell Leukemia and VariantParticipants currently recruited/enrolled18-125 YearsNCI Adult
21-C-0017Magnetic Resonance Image (MRI) Guided High Energy Ultrasound for Focal Prostate Cancer AblationRecruitment has not started18-125 YearsNCI Adult
21-C-0015Phase II Trial Evaluating the Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment with Immune Checkpoint Inhibition (ICI) in Patients with Newly Diagnosed Glioblastoma or GliosarcomaParticipants currently recruited/enrolled18-125 YearsNCI Adult
21-C-0014Phase 1 Study of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination with Polatuzumab (ViPOR-P) in Relapsed/Refractory B-cell LymphomaParticipants currently recruited/enrolled18-125 YearsNCI Adult
21-C-0013A Phase I/II Study of Adjuvant PRGN-2012 in Adult Patients with Recurrent Respiratory PapillomatosisParticipants currently recruited/enrolled18-125 YearsNCI Adult
21-C-0012Individualized Response Assessment to Heated Intraperitoneal Chemotherapy (HIPEC) for the Treatment of Peritoneal Carcinomatosis from Ovarian, Colorectal, Appendiceal, or Peritoneal Mesothelioma HistologiesParticipants currently recruited/enrolled18-125 YearsNCI Adult
21-C-0009A Natural History Study of Children and Adults with Olfactory NeuroblastomaParticipants currently recruited/enrolled3-125 YearsNCI Adult
21-C-0007A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon CancersParticipants currently recruited/enrolled18-125 YearsNCI Adult
21-C-0006Phase I/II Study Evaluating Safety and Efficacy of Tivozanib (AV-951) in CholangiocarcinomaClinical hold/Recruitment or enrollment suspended18-125 YearsNCI Adult
21-C-0001A Phase I/II Study of M9241 in Combination with Docetaxel in Adults with Metastatic Castration Sensitive and Castration Resistant Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI Adult
20-NR-0124Development of Immersive VR Environments to Induce and Evaluate Cognitive Fatigability: User Experience and Healthy Control StudiesNo longer recruiting/follow-up only18-75 YearsNINR Adult
20-NR-0003A Proof-of-Concept Trial on the Effect of Ketamine on FatigueParticipants currently recruited/enrolled18-70 YearsNINR Adult
20-N-0077Study of Volition: Behavioral analysis and Clinical Neurophysiological AnalysisParticipants currently recruited/enrolled25-45 YearsNINDSAdult
20-N-0060Mechanisms Underlying the Beneficial Effects of Naps on Motor LearningParticipants currently recruited/enrolled18-80 YearsNINDSAdult
20-M-0159Role of GABAergic Transmission in Auditory Processing in Autism Spectrum DisorderParticipants currently recruited/enrolled14-25 YearsNIMH Adult
20-M-0157PET Imaging of Cyclooxygenase in Participants with Major Depressive Disorder (MDD)Participants currently recruited/enrolled18-70 YearsNIMH Adult
20-M-0082Phase 1 Study: PET Imaging of Cyclooxygenases in Neurodegenerative Brain DiseaseParticipants currently recruited/enrolled18-99 YearsNIMH Adult
20-I-0160Dose-Escalation Study of a Low Pathogenicity Avian H10N7 Influenza Virus in a Healthy Human Challenge ModelRecruitment has not started18-50 YearsNIAIDAdult
20-I-0145VRC 323: A Phase I Open-Label Clinical Trial to Evaluate the Dose, Safety, Tolerability and Immunogenicity of an Influenza H10 Stabilized Stem Ferritin Vaccine, VRC-FLUNPF0103-00-VP, in Healthy AdultsCompleted Study; data analyses ongoing18-70 YearsNIAIDAdult
20-I-0132A Multicentre, Randomised, Double-blind, Parallel-group, Placebo-controlled, 24-week Phase 3 Study with an Open-label Extension to Evaluate the Efficacy and Safety of Benralizumab in Patients with Hypereosinophilic Syndrome (HES)Participants currently recruited/enrolled12-130 YearsNIAIDAdult
20-I-0111COVID-19-associated Lymphopenia Pathogenesis Study in BloodParticipants currently recruited/enrolled18-125 YearsNIAIDAdult
20-I-0096VRC 611: A Phase 1 Safety and Pharmacokinetic Study to Evaluate a Human Monoclonal Antibody (mAb) VRC-HIVMAB0102-00-AB (CAP256V2LS) Administered via Subcutaneous and Intravenous Injection in Healthy AdultsNo longer recruiting/follow-up only18-60 YearsNIAIDAdult
20-I-0083SARS-COV2 Pandemic Serosurvey and Blood SamplingCompleted Study; data analyses ongoing18-125 YearsNIAIDAdult
20-HG-0156A Multicenter, Multinational, Randomized, Double-Blind, Placebo-Controlled Study to Assess The Efficacy, Pharmacodynamics, Pharmacokinetics, Safety, and Tolerability of Venglustat in Late-Onset GM2 Gangliosidosis (Tay-Sachs Disease And Sandhoff Disease) No longer recruiting/follow-up only2-125 YearsNHGRIAdult
20-HG-0034A Multi-Cohort Phase 2 Dose-Escalation Study of MK-7075 (Miransertib) in Proteus SyndromeParticipants currently recruited/enrolled3-125 YearsNHGRIAdult
20-HG-0025A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Efficacy of ManNAc in Subjects with GNE MyopathyParticipants currently recruited/enrolled18-125 YearsNHGRIAdult
20-H-0141Long-term Follow-up of Subjects With Sickle Cell Disease Treated With Ex Vivo Gene Therapy Using Autologous Hematopoietic Stem Cells Transduced With a Lentiviral VectorEnrolling by Invitation18-125 YearsNHLBIAdult
20-H-0137A Study to Evaluate the Effects of Fixed Dose Flavonoid Isoquercetin on Thrombo-Inflammatory Biomarkers in Subjects with Stable Sickle Cell DiseaseCompleted Study; data analyses ongoing18-46 YearsNHLBIAdult
20-H-0049NHLBI DIR Cardiovascular Branch PK Papyrus Covered Stent Ethics Oversight of Humanitarian Use Device for Treatment of Acute Perforations of Native Coronary Arteries and Coronary Bypass Grafts in Vessels 2.5 to 5.0 mm in DiameterEnrolling by Invitation18-125 YearsNHLBIAdult
20-H-0044Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in PsoriasisCompleted Study; data analyses ongoing18-80 YearsNHLBIT-Cell
20-H-0033Early Initiation of Oral Therapy with Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia (SAA)Participants currently recruited/enrolled3-125 YearsNHLBIT-Cell
20-H-0016Duvelisib for Ibrutinib-Resistant Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)Completed Study; data analyses ongoing18-125 YearsNHLBIAdult
20-EI-0052A Phase I/IIa Trial for Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated with Age-Related Macular DegenerationParticipants currently recruited/enrolled55-125 YearsNEI Adult
20-E-0143Serological Surveillance for COVID-19 in Central North CarolinaParticipants currently recruited/enrolled18-125 YearsNIEHSAdult
20-E-0108A Prospective Natural History Study of Smoking, Immune Cell Profiles, Epigenetics and COVID-19Completed Study; data analyses ongoing30-55 YearsNIEHSAdult
20-DK-0018Prebiotics and Metformin Influences Gut and Hormones in Type 2 Diabetes YouthCompleted Study; data analyses ongoing10-25 YearsNIDDKAdult
20-D-0131Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sj(SqrRoot)(Delta)gren's Syndrome; a Phase Ib-IIa Placebo-controlled Clinical Trial and Associated Mechanistic StudiesParticipants currently recruited/enrolled18-75 YearsNIDCRAdult
20-CH-0165Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals with Androgen InsensitivityParticipants currently recruited/enrolled0-99 YearsNICHDAdult
20-CH-0126Data Collection Study of Pediatric and Adolescent Gynecology ConditionsParticipants currently recruited/enrolled0-125 YearsNICHDAdult
20-CC-0092Plasma Collection from Convalescent and/or Immunized Donors for the Treatment of COVID-19Completed Study; data analyses ongoing18-125 YearsCC Adult
20-CC-0036Exploring a Dietary Behavior Intervention in African-Americans at Risk for Cardiovascular Disease: A Community Acceptability and Feasibility StudyParticipants currently recruited/enrolled18-125 YearsCC Adult
20-C-0167Close Assessment and Testing for Chronic Graft-vs-Host Disease (CATCH Study)Participants currently recruited/enrolled18-125 YearsNCI Adult
20-C-0164Multiparametric Magnetic Resonance Imaging of the Prostate to Assess Disease Progression and Genomics in Patients Undergoing Active Surveillance for Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI Adult
20-C-0162A Phase 1 Study of Venetoclax with Obinutuzumab and Magrolimab (VENOM) in Relapsed and Refractory Indolent B-cell MalignanciesParticipants currently recruited/enrolled18-125 YearsNCI Adult
20-C-0155Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetics, Immune and Clinical Activity of SX-682 in Combination with BinTrafusp Alfa (M7824 or TGF-beta "Trap"/PD-L1) with CV301 TRICOM in Advanced Solid Tumors (STAT)No longer recruiting/follow-up only18-125 YearsNCI Adult
20-C-0154Pilot Study of DS-8201a Pharmacodynamics in Patients with HER2-expressing Advanced Solid TumorsParticipants currently recruited/enrolled18-125 YearsNCI Adult
20-C-0152Phase II Study of combination of Trametinib (MEK inhibitor) and Hydroxychloroquine (HCQ) (autophagy inhibitor) in Patients with KRAS Mutation Refractory Bile Tract Carcinoma (BTC).Participants currently recruited/enrolled18-125 YearsNCI Adult
20-C-0150Phase II Randomized Trial of Bethesda Protocol Compared to Cambridge Method for Detection of Early Stage Gastric Cancer in CDH1 Mutation CarriersRecruitment has not started18-125 YearsNCI Adult
20-C-0149Phase II Trial of Olaparib (LYNPARZA) plus Durvalumab (IMFINZI) in EGFR-Mutated Adenocarcinomas that Transform to Small Cell Lung Cancer (SCLC) and Other Neuroendocrine TumorsParticipants currently recruited/enrolled18-125 YearsNCI Adult
20-C-0127A Phase 1 Study of Romidepsin, CC-486 (5-azacitidine), dexamethasone, and lenalidomide (RAdR) for relapsed/refractory T-cell malignanciesParticipants currently recruited/enrolled18-125 YearsNCI T-Cell
20-C-0107Clinical, Genetic, and Epidemiologic Study of Children and Adults with RASopathiesParticipants currently recruited/enrolled0-125 YearsNCI Adult
20-C-0070A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Patients with Inborn Errors of ImmunityParticipants currently recruited/enrolled4-69 YearsNCI T-Cell
20-C-0065A Phase II Feasibility Trial Using Immersive Virtual Reality (VR) at the Time of Clinical Evaluation to Improve Psychological Distress and Anxiety in Primary Brain Tumor (PBT) PatientsParticipants currently recruited/enrolled18-125 YearsNCI Adult
20-C-0062A phase 1b Study of Nivolumab in Patients with Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)Participants currently recruited/enrolled18-125 YearsNCI Adult
20-C-0028Phase 1/2 Study of Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells (CD33CART) in Children and Young Adults with Relapsed/Refractory Acute Myeloid LeukemiaParticipants currently recruited/enrolled3-35 YearsNCI Adult
20-C-0023First-in-Human Phase I Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of Metarrestin (ML-246) in Subjects with Metastatic Solid TumorsParticipants currently recruited/enrolled12-125 YearsNCI Adult
20-C-0012A Phase I Study of Bintrafusp alfa (M7824) and NHS-IL12 (M9241) Alone and in Combination with Stereotactic Body Radiation Therapy (SBRT) in Adults with Metastatic Non-Prostate Genitourinary MalignanciesParticipants currently recruited/enrolled18-125 YearsNCI Adult
20-AG-0087Ketone ester effects on biomarkers of brain metabolism and cognitive performance in cognitively intact adults (Bullet) 55 years old. A double-blinded randomized controlled clinical trialParticipants currently recruited/enrolled55-125 YearsNIA Adult
20-AA-0057The Effect of Acute Alcohol Intoxication on Neural Processes During Decisions to Engage in HIV Risk BehaviorsParticipants currently recruited/enrolled21-65 YearsNIAAAAdult
19-NR-0098Patient-Centered Assessment of Symptoms and OutcomesParticipants currently recruited/enrolled18-125 YearsNINR Adult
19-N-0114Modulating the Hippocampal and Striatal Memory Networks with rTMSCompleted Study; data analyses ongoing18-40 YearsNINDSAdult
19-N-0036Exploring the Relationship Between Brain Asymmetry and AttentionCompleted Study; data analyses ongoing18-35 YearsNINDSAdult
19-M-0107The Mechanism of Action Underlying Ketamine's Antidepressant Effects: An Investigation of the AMPA Throughput Theory in Patients with Treatment-Resistant Major DepressionParticipants currently recruited/enrolled18-70 YearsNIMH Adult
19-M-0095PET Imaging of Neuroinflammation in Neurodegenerative Diseases via a Novel TSPO RadioligandParticipants currently recruited/enrolled18-125 YearsNIMH Adult
19-M-0054Mapping the Phenotype in Adults with Phelan-McDermid SyndromeCompleted Study; data analyses ongoing0-125 YearsNIMH Adult
19-I-0133Paradoxical Tuberculosis Reactions in Patients without HIV InfectionParticipants currently recruited/enrolled18-125 YearsNIAIDAdult
19-I-0069Phase I Open-Label Study of Safety and Immunogenicity of AD4-HIV Envelope Vaccine Vectors in Healthy VolunteersParticipants currently recruited/enrolled18-65 YearsNIAIDAdult
19-I-0058Mucosal Correlates of Protection After Influenza Viral Challenge of Vaccinated and Unvaccinated Healthy VolunteersCompleted Study; data analyses ongoing18-55 YearsNIAIDAdult
19-I-0027A Phase 2 Randomized Double-Blinded Placebo-Controlled Study to Evaluate the Safety and Efficacy of Subcutaneous Sarilumab in Improving the Quality of Life in Subjects with Indolent Systemic MastocytosisParticipants currently recruited/enrolled18-75 YearsNIAIDAdult
19-I-0022A Prospective, Multicenter Study to Compare and Validate Endoscopic, Histologic, Molecular, and Patient-Reported Outcomes in Pediatric and Adult Patients with Eosinophilic Esophagitis (EoE), Gastritis (EG) and Colitis (EC)Participants currently recruited/enrolled3-125 YearsNIAIDAdult
19-H-0139Investigation of the Natural Progression of Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenia of Undetermined Significance.Participants currently recruited/enrolled18-125 YearsNHLBIAdult
19-H-0111Early Clonal Dynamics During Venetoclax Treatment for Chronic Lymphocytic Leukemia (CLL)Participants currently recruited/enrolled18-125 YearsNHLBIAdult
19-H-0100Best Noninvasive Predictor of Renal Function in Assessing Adult Sickle NephropathyCompleted Study; data analyses ongoing18-125 YearsNHLBIAdult
19-H-0057Multiple Patient Program for Lamprene (clofazimine) for the treatment of Non-Tuberculous Mycobacterial (NTM) Infections- CLAM320B2002MParticipants currently recruited/enrolled18-99 YearsNHLBIAdult
19-H-0001Response to the SHINGRIX Varicella Zoster Virus (VZV) Vaccine in Chronic Lymphocytic Leukemia (CLL) Patients that are Treatment Na(SqrRoot) ve or Receiving Bruton s-tyrosine Kinase Inhibitor (BTK-I) TherapyNo longer recruiting/follow-up only18-125 YearsNHLBIAdult
19-EI-0056A Survey Study of Retinitis Pigmentosa (RP) Clinical Measures and Repeatability Testing of Potential Outcome Measures.Participants currently recruited/enrolled12-125 YearsNEI Adult
19-E-0110Reproductive Axis Maturation in the Early Post-Menarchal Years: A Pilot StudyParticipants currently recruited/enrolled8-34 YearsNIEHSAdult
19-DK-0066The Evaluation and Management of Endocrine-Related Conditions and PhysiologyParticipants currently recruited/enrolled18-90 YearsNIDDKAdult
19-CH-0051Long-Term Follow-UP of Survivors of Pediatric Cushing DiseaseParticipants currently recruited/enrolled2-90 YearsNICHDAdult
19-CH-0026Randomized, Double-Blind, Placebo-Controlled Study Plus Open Label Extension with a Double-Blind, Placebo-Controlled, Randomized Withdrawal Period of Diazoxide Choline Extended-Release Tablets (DCCR, Soleno Therapeutics, Inc.) in Participants with PraderNo longer recruiting/follow-up only4-125 YearsNICHDAdult
19-CC-0055Cardiovascular Disease in HIV and Hepatitis C: Risk Outcomes after Hepatitis C EradicationParticipants currently recruited/enrolled18-125 YearsCC Adult
19-CC-0005Short or Long Infusion Duration for Platelets: The SOLID Platelet StudyParticipants currently recruited/enrolled18-100 YearsCC Adult
19-C-0143A Phase II Study Using the Administration of Autologous T-Cells Engineered using the Sleeping Beauty Transposon/Transposase System to Express T-Cell Receptors Reactive Against Mutated Neoantigens in Patients with Metastatic CancerParticipants currently recruited/enrolled18-70 YearsNCI T-Cell
19-C-0138Phase I/II Study of Lu-177-DOTATATE (Lutathera) in Combination with Olaparib in Inoperable Gastroenteropancreatico Neuroendocrine Tumors (GEP-NET)Participants currently recruited/enrolled18-125 YearsNCI Adult
19-C-0137A Phase II Study of Ipilimumab, Cabozantinib, and NIvolumab in Rare Genitourinary Cancers (ICONIC)Participants currently recruited/enrolled18-125 YearsNCI Adult
19-C-0134A Phase 1/1b Study of Enhancement of Immune Reconstitution and Vaccine Responses with Administration of Recombinant Human IL-7-hyFc (NT-I7) in Older Subjects Following ChemotherapyParticipants currently recruited/enrolled60-125 YearsNCI Adult
19-C-0131Development and Psychometric Testing of a Pediatric Chronic Graft- Versus-Host Disease (GVHD) Symptom Scale (PCSS)Participants currently recruited/enrolled5-125 YearsNCI Adult
19-C-0127A Phase II Study of LMB-100 Followed by Pembrolizumab in the Treatment of Adults with Mesothelin-Expressing Non-Squamous Non-Small Cell Lung Cancer (NSCLC)No longer recruiting/follow-up only18-125 YearsNCI Adult
19-C-0112Phase I/II Study De-intensifying Exposure of Post-transplantation Cyclophosphamide as GVHD Prophylaxis after HLA-haploidentical Hematopoietic Cell Transplantation for Hematologic MalignanciesParticipants currently recruited/enrolled12-125 YearsNCI Adult
19-C-0102A Phase I Clinical Trial of T-cells Expressing an anti-SLAMF7 CAR for Treating Multiple MyelomaCompleted Study; data analyses ongoing18-73 YearsNCI T-Cell
19-C-0094A Phase II Study of Combined Treatment of Durvalumab, Bevacizumab, Tremelimumab and Transarterial Chemoembolization (TACE) in Subjects with Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinoma (BTC)Participants currently recruited/enrolled18-125 YearsNCI Adult
19-C-0085Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Peripheral T cell LymphomaClinical hold/Recruitment or enrollment suspended12-125 YearsNCI T-Cell
19-C-0082Natural History Study of Children and Adults with ChordomaParticipants currently recruited/enrolled2-125 YearsNCI Adult
19-C-0076A Phase 1 Study of Interleukin-15 in Combination with Avelumab (Bavencio) in Relapsed/Refractory Mature T-cell MalignanciesCompleted Study; data analyses ongoing18-125 YearsNCI T-Cell
19-C-0049Long Term Follow-up of Mesothelioma Patients and Their Family Members with Germline Mutations in BAP1 and Other GenesParticipants currently recruited/enrolled2-125 YearsNCI Adult
19-C-0041Birinapant and Intensity Modulated Re-Irradiation Therapy (IMRRT) for Locoregionally Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC)Participants currently recruited/enrolled18-125 YearsNCI Adult
19-C-0040Natural History Study of Men at High Genetic Risk for Prostate CancerParticipants currently recruited/enrolled30-75 YearsNCI Adult
19-C-0039Perioperative MVT-5873, a Fully Human Monoclonal Antibody Against a CA 19-9 Epitope, for Operable CA 19-9 Producing Pancreatic Cancers, Cholangiocarcinomas, and Metastatic Colorectal CancersCompleted Study; data analyses ongoing18-125 YearsNCI Adult
19-C-0033Phase II Study of Nivolumab (anti-PD1), Tadalafil and Oral Vancomycin in Patients with Refractory Primary Hepatocellular Carcinoma or Liver Dominant Metastatic Cancer from Colorectal or Pancreatic CancersCompleted Study; data analyses ongoing18-125 YearsNCI Adult
19-C-0030A Phase 2 Study of Response-Adapted Therapy with Copanlisib and Rituximab in Untreated Follicular LymphomaParticipants currently recruited/enrolled18-125 YearsNCI Adult
19-C-0025Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic MalignanciesEnrolling by Invitation18-125 YearsNCI Adult
19-C-0023A Phase II Study of Olaparib (AZD2281) in Patients with Metastatic/Advanced Urothelial Carcinoma and other genitourinary tumors with DNA-Repair DefectsParticipants currently recruited/enrolled18-125 YearsNCI Adult
19-C-0016Natural History and Biospecimen Acquisition Study for Children and Adults with Rare Solid TumorsParticipants currently recruited/enrolled0-125 YearsNCI Adult
19-C-0010A Phase 1 Trial of MK-3475 Plus Ziv-Aflibercept in Patients with Advanced Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Adult
19-C-0006Phase II Trial Evaluating Nivolumab In Patients With IDH-Mutant Gliomas With And Without Hypermutator PhenotypeParticipants currently recruited/enrolled18-125 YearsNCI Adult
18-N-0133Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal SurgeryParticipants currently recruited/enrolled18-125 YearsNINDSAdult
18-N-0077Cytokine Microdialysis For Real Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint BlockadeCompleted Study; data analyses ongoing18-125 YearsNINDSAdult
18-N-0066Investigating Epilepsy: Screening and EvaluationParticipants currently recruited/enrolled8-125 YearsNINDSAdult
18-N-0020The Natural History of Blood-Brain Barrier Disruption in Stroke Patients with White Matter Hyperintensities (A Cohort Study)No longer recruiting/follow-up only18-125 YearsNINDSAdult
18-M-0015Development of Non-Invasive Brain Stimulation TechniquesParticipants currently recruited/enrolled18-65 YearsNIMH Adult
18-I-0139Defining Skin Immunity of a Bite of Key Insect Vectors in HumansCompleted Study; data analyses ongoing18-64 YearsNIAIDAdult
18-I-0105VRC 609: A Phase I, Open-Label, Dose-Escalation Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIVMAB091-00-AB (N6LS), Administered Intravenously or Subcutaneously with or without Recombinant Human Hyaluronidase PH20 (rHuPH2Completed Study; data analyses ongoing18-50 YearsNIAIDAdult
18-I-0092A Phase 2, Open-Label Study to Assess the Immunogenicity of the 9-Valent Human Papillomavirus Recombinant Vaccine in Patients with Idiopathic CD4 T cell LymphocytopeniaParticipants currently recruited/enrolled18-70 YearsNIAIDAdult
18-I-0039Challenge Infection of Healthy Adult Volunteers with RSV A2Completed Study; data analyses ongoing18-50 YearsNIAIDAdult
18-I-0030VRC 603: A Phase 1 Dose-Escalation Study of the Safety of AAV8-VRC07 (VRC-HIVAAV070-00-GT) Recombinant AAV Vector Expressing VRC07 HIV-1 Neutralizing Antibody in Antiretroviral-Treated, HIV-1 Infected Adults with Controlled ViremiaNo longer recruiting/follow-up only18-65 YearsNIAIDAdult
18-I-0022Use of Ustekinumab (Anti-IL-12/23p40 Monoclonal Antibody) in Patients with Leukocyte Adhesion Deficiency Type 1 (LAD1) who have Inflammatory PathologyParticipants currently recruited/enrolled12-65 YearsNIAIDAdult
18-HG-0064A Natural History Study of Patients with Generalized Arterial Calcification of Infancy (GACI) or Autosomal Recessive Hypophosphatemic Rickets Type 2 (ARHR2)Completed Study; data analyses ongoing0-125 YearsNHGRIAdult
18-H-0146Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell DiseaseParticipants currently recruited/enrolled18-80 YearsNHLBIAdult
18-H-0019Effect of Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in AdultsParticipants currently recruited/enrolled18-125 YearsNHLBIAdult
18-EI-0068An Investigation of Vitamin A Palmitate Supplementation in Patients with Reticular Pseudodrusen (RPD) and Delayed Dark AdaptationParticipants currently recruited/enrolled50-125 YearsNEI Adult
18-EI-0067An Investigation of Vitamin A Palmitate Supplementation in Patients with Age-Related Macular Degeneration (and without reticular pseudodrusen) and Delayed Dark AdaptationParticipants currently recruited/enrolled50-125 YearsNEI Adult
18-EI-0055A Phase III Multicenter Randomized Sham Controlled Study to Determine the Safety and Efficacy of NT-501 in Macular Telangiectasia Type 2Completed Study; data analyses ongoing21-80 YearsNEI Adult
18-EI-0046Perception, Sensation, Cognition and Action in HumansParticipants currently recruited/enrolled18-65 YearsNEI Adult
18-DK-0123Treatment of Chronic Delta Hepatitis with Lonafarnib, Ritonavir and Lambda InterferonCompleted Study; data analyses ongoing18-125 YearsNIDDKAdult
18-DK-0091Long-Term Follow-Up Of Subjects With CHC Who Achieved A Sustained Virological Response Following Therapy With Direct Acting Antiviral AgentsParticipants currently recruited/enrolled18-125 YearsNIDDKAdult
18-DK-0044Effect of Ultra Processed versus Unprocessed Diets on Energy IntakeCompleted Study; data analyses ongoing18-50 YearsNIDDKAdult
18-D-0121Natural History of Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy ControlsParticipants currently recruited/enrolled18-100 YearsNIDCRAdult
18-D-0114An Open Label Pilot Study of Denosumab Treatment for Fibrous DysplasiaNo longer recruiting/follow-up only18-125 YearsNIDCRAdult
18-CH-0002Investigations of Juvenile Neuronal Ceroid Lipofuscinosis (CLN3)Participants currently recruited/enrolled0-125 YearsNICHDAdult
18-CH-0001Mirror Neuron Network Dysfunction as an Early Biomarker of Neurodevelopmental DisorderParticipants currently recruited/enrolled0-65 YearsNICHDAdult
18-CC-0117PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive SubjectsCompleted Study; data analyses ongoing18-70 YearsCC Adult
18-CC-0087Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy VolunteersCompleted Study; data analyses ongoing18-65 YearsCC Adult
18-CC-0079Pilot RCT of Web-based Behavioral Sleep Intervention for Individuals with Alcohol Use DisorderCompleted Study; data analyses ongoing18-65 YearsCC Adult
18-CC-0013A Randomized, Double-Blind, Placebo-Controlled Study of a Single Dose of Pembrolizumab in HIV-Infected PatientsParticipants currently recruited/enrolled18-99 YearsCC T-Cell
18-C-0147Phase 1 with Expansion Cohorts in a Study of NEO-201 In Adults with Chemo-Resistant Solid TumorsParticipants currently recruited/enrolled18-125 YearsNCI Adult
18-C-0143A Phase 1 Study of Intraperitoneal MCY-M11 Therapy for Women with Platinum Resistant High Grade Serous Adenocarcinoma of the Ovary, Primary Peritoneum, or Fallopian Tube, or Subjects with Peritoneal Mesothelioma with Recurrence after Prior ChemotherapyCompleted Study; data analyses ongoing18-125 YearsNCI Adult
18-C-0135Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or DysregulationParticipants currently recruited/enrolled4-125 YearsNCI T-Cell
18-C-0126NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice)Completed Study; data analyses ongoing1-21 YearsNCI Adult
18-C-0125A Phase I Clinical Trial of T cells Expressing a Novel Fully-human Anti-BCMA CAR for Treating Multiple MyelomaNo longer recruiting/follow-up only18-73 YearsNCI Adult
18-C-0102Pilot Study of the MEK1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) for Adults with Neurofibromatosis Type 1 (NF1) and Cutaneous Neurofibromas (cNF)Completed Study; data analyses ongoing18-125 YearsNCI Adult
18-C-0093Pilot Study of Medication Adherence in Children, Adolescents, and Adults with Neurofibromatosis Type 1 (NF1) on Clinical Treatment TrialsNo longer recruiting/follow-up only3-125 YearsNCI Adult
18-C-0080Feasibility and Preliminary Efficacy of an Enhanced Mindfulness Intervention for Children and Young Adults with High Grade or High-Risk Cancer and Their Caregivers: A Pilot Randomized Controlled TrialCompleted Study; data analyses ongoing5-125 YearsNCI Adult
18-C-0076Bicalutamide With or Without Metformin for Biochemical Recurrence in Prostate Cancer Patients (BIMET-1)Completed Study; data analyses ongoing18-85 YearsNCI Adult
18-C-0062Phase 2 Trial of XL184 (Cabozantinib) an Oral Small-Molecule Inhibitor of Multiple Kinases, in Children and Young Adults with Refractory Sarcomas, Wilms Tumor, and Other Rare TumorsCompleted Study; data analyses ongoing2-30 YearsNCI Adult
18-C-0059Phase 1 Dose Escalation Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults with Recurrent or Refractory CD19/CD22-expressing B Cell MalignanciesParticipants currently recruited/enrolled3-39 YearsNCI Adult
18-C-0058A Pilot Study to Evaluate the Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration in Men with Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy FemalesParticipants currently recruited/enrolled18-125 YearsNCI Adult
18-C-0056Phase II Trial of M7824 in Subjects with HPV Associated MalignanciesNo longer recruiting/follow-up only18-125 YearsNCI Adult
18-C-0049A Phase II Study Using the Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in Patients with Metastatic CancerParticipants currently recruited/enrolled18-72 YearsNCI T-Cell
18-C-0034A Phase 2 Study of ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial CarcinomaCompleted Study; data analyses ongoing18-125 YearsNCI Adult
18-C-0026A Phase 2 Study of Inotuzumab Ozogamicin (NSC# 772518, IND#133494) in Children and Young Adults with Relapsed or Refractory CD22+ B-Acute Lymphoblastic Leukemia (B-ALL)Participants currently recruited/enrolled1-21 YearsNCI Adult
18-C-0024A Single-Arm Phase II Study of Hepatic Artery Infusion Pump Chemotherapy with Floxuridine and Dexamethasone in Combination with Systemic Chemotherapy for Patients with Colorectal Cancer Metastatic to the LiverParticipants currently recruited/enrolled18-125 YearsNCI Adult
18-AR-0081Investigation of the Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease and Related Inflammatory ConditionsParticipants currently recruited/enrolled0-125 YearsNIAMSAdult
18-AA-0098Investigating a Response Modulation Hypothesis of Socioemotional Processing associated with Alcohol Use DisorderParticipants currently recruited/enrolled21-65 YearsNIAAAAdult
17-N-0168Influence of Brain Oscillation-Dependent TMS on Motor FunctionParticipants currently recruited/enrolled18-125 YearsNINDSAdult
17-N-0145PD-1 Inhibition to Determine CNS Reservoir of HIV-InfectionCompleted Study; data analyses ongoing18-120 YearsNINDSAdult
17-N-0055Functional Connectivity as a Biomarker of rTMSCompleted Study; data analyses ongoing18-125 YearsNINDSAdult
17-N-0031Detailed Evaluation of the Neurophysiology of Surround Inhibition in the Human Motor CortexCompleted Study; data analyses ongoing18-70 YearsNINDSAdult
17-MD-0015Understanding how cigarette direct mail marketing influence smoking behaviors among high and low socioeconomic status young adult smokersRecruitment has not started18-29 YearsNIMHDAdult
17-M-0181Recruitment and Characterization of Healthy Research Volunteers for NIMH Intramural StudiesParticipants currently recruited/enrolled18-125 YearsNIMH Adult
17-M-0179Evaluation of a Novel PET Radioligand to Image Cyclooxygenase-1 (COX-1)Participants currently recruited/enrolled18-99 YearsNIMH Adult
17-M-0147Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive EpisodesParticipants currently recruited/enrolled18-65 YearsNIMH Adult
17-I-0101An Open-Label, Proof of Concept Study of Vorinostat for the Treatment of Moderate-to-Severe Crohn's Disease and Maintenance Therapy with UstekinumabParticipants currently recruited/enrolled18-65 YearsNIAIDAdult
17-I-0067Sanaria PfSPZ Challenge with Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Dose Escalation Trial to Determine Safety and Development of Protective Efficacy after Exposure to Only Pre-erythrocytic Stages of Plasmodium falciparumCompleted Study; data analyses ongoing18-50 YearsNIAIDAdult
17-I-0016Studies of the Natural History, Pathogenesis, and Outcome of Autoinflammatory Diseases (NOMID/CAPS, DIRA, CANDLE, SAVI, NLRC4-MAS, Still's-like Diseases, and Other Undifferentiated Autoinflammatory Diseases)Participants currently recruited/enrolled0-99 YearsNIAIDAdult
17-H-0162Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments: A Multi-Level, Community-Based Physical Activity InterventionParticipants currently recruited/enrolled21-75 YearsNHLBIAdult
17-H-0124Peripheral Blood Stem Cell Collection for Sickle Cell Disease (SCD) Patients Using PlerixaforCompleted Study; data analyses ongoing18-125 YearsNHLBIAdult
17-H-0118A Phase II Study Of Ibrutinib, Fludarabine, and Pembrolizumab in High-Risk or Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)No longer recruiting/follow-up only18-125 YearsNHLBIAdult
17-H-0095Heart Catheterization Using Magnetic Resonance Imaging (MRI) Fluoroscopy and Passive GuidewiresParticipants currently recruited/enrolled18-125 YearsNHLBIAdult
17-H-0069Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell DiseaseParticipants currently recruited/enrolled2-125 YearsNHLBIAdult
17-H-0026Pembrolizumab and Decitabine for Refractory or Relapsed Acute Myeloid LeukemiaCompleted Study; data analyses ongoing18-99 YearsNHLBIAdult
17-EI-0112A Long-term Follow-up Study of Participants Enrolled in 11-EI-0147: Longitudinal Investigation of Dark Adaptation in Participants with Age-Related Macular Degeneration (DA_AMD)Participants currently recruited/enrolled50-125 YearsNEI Adult
17-EI-0008The Natural History of Geographic Atrophy Associated with Age-Related Macular DegenerationParticipants currently recruited/enrolled55-125 YearsNEI Adult
17-E-0161An Open-label Study of Sodium Thiosulfate for Treatment of Calcinosis Associated with Juvenile and Adult DermatomyositisNo longer recruiting/follow-up only7-85 YearsNIEHSAdult
17-DK-0013Therapeutic Targets in African-American Youth with Type 2 DiabetesParticipants currently recruited/enrolled12-25 YearsNIDDKAdult
17-CH-0014Pilot Study of Mobile Attention Training in Overweight Female AdolescentsParticipants currently recruited/enrolled12-21 YearsNICHDAdult
17-C-0175CC-4047-BRN-001: A Phase 2 Clinical Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults with Recurrent or Progressive Primary Brain TumorsCompleted Study; data analyses ongoing3-20 YearsNCI Adult
17-C-0174Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman DiseaseParticipants currently recruited/enrolled18-125 YearsNCI Adult
17-C-0164A Phase 1b/2 Trial of Hu5F9-G4 in Combination with Rituximab or Rituximab + Chemotherapy in Patients with Relapsed/Refractory B-cell Non-Hodgkin's LymphomaNo longer recruiting/follow-up only18-125 YearsNCI Adult
17-C-0158A Feasibility Study of Mobile Sensor Technologies to Assess General Symptomology of Cancer PatientsEnrolling by Invitation18-125 YearsNCI Adult
17-C-0156Longitudinal Sample Collection and Tracking for the Developmental Therapeutics Clinic, National Cancer InstituteParticipants currently recruited/enrolled18-125 YearsNCI Adult
17-C-0137Leukapheresis for CAR or Adoptive Cell Therapy ManufacturingEnrolling by Invitation3-65 YearsNCI T-Cell
17-C-0117A Phase 1/2a, Open-Label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-Tumor Activity of PEN-866 in Advanced Solid MalignanciesCompleted Study; data analyses ongoing18-125 YearsNCI Adult
17-C-0115Phase I/II Study of T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic RadiosurgeryNo longer recruiting/follow-up only18-125 YearsNCI Adult
17-C-0105Prospective Study of Clonal Evolution in Follicular LymphomaParticipants currently recruited/enrolled18-125 YearsNCI Adult
17-C-0102Phase II Trial of the Immune Checkpoint Inhibitor Nivolumab in Patients with Recurrent Select Rare CNS CancersParticipants currently recruited/enrolled18-99 YearsNCI Adult
17-C-0100Collection of Malignant Ascites, Pleural Fluid and Blood from Patients with Solid TumorsNo longer recruiting/follow-up only18-125 YearsNCI Adult
17-C-0092A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination with Immune Checkpoint Inhibition in Refractory Colorectal CancerCompleted Study; data analyses ongoing18-125 YearsNCI T-Cell
17-C-0087Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ ParagangliomaParticipants currently recruited/enrolled18-125 YearsNCI Adult
17-C-0048Anti-CD30 CAR T Cells with Fully-human Binding Domains for Treating CD30-expressing Lymphomas Including Anaplastic Large Cell LymphomasCompleted Study; data analyses ongoing18-73 YearsNCI T-Cell
17-C-0045A Phase I Study of Indenoisoquinoline LMP744 in Adults With Relapsed Solid Tumors and LymphomasParticipants currently recruited/enrolled18-125 YearsNCI Adult
17-C-0037Phase II Trial of LB100, a Protein Phosphatase 2A Inhibitor, in Recurrent GlioblastomaParticipants currently recruited/enrolled18-125 YearsNCI Adult
17-C-0034A Randomized, Double Blind Phase II Trial of Surgery, Radiation Therapy Plus Temozolomide and Pembrolizumab with and without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)Completed Study; data analyses ongoing18-125 YearsNCI Adult
17-C-0028A Pilot Study of Vincristine Sulfate Liposome Injection (Marqibo ) in Combination with Chemotherapy for Children, Adolescents, and Young Adults with Relapse of Acute Lymphoblastic LeukemiaCompleted Study; data analyses ongoing2-21 YearsNCI Adult
17-C-0027Long-Term Follow up of Patients Undergoing Hematopoietic Stem Cell TransplantationParticipants currently recruited/enrolled4-125 YearsNCI Adult
17-C-0009Phase I Trial of Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) plus Temozolomide versus Temozolomide alone in Adults with Recurrent Anaplastic Astrocytoma and GlioblastomaCompleted Study; data analyses ongoing18-125 YearsNCI Adult
17-AT-0155Sociocultural & Biobehavioral Influences on Pain Expression and AssessmentParticipants currently recruited/enrolled18-60 YearsNCCIHAdult
17-AT-0075Sensory and Opioid Mechanisms of Affective TouchCompleted Study; data analyses ongoing18-50 YearsNCCIHAdult
17-AA-0178Dopaminergic Modulation of Brain Activation Using Simultaneous PET/Pharmacological MRIEnrolling by Invitation18-55 YearsNIAAAAdult
17-AA-0171Nicotinic Receptor Genetic Variation and Alcohol RewardParticipants currently recruited/enrolled21-60 YearsNIAAAAdult
17-AA-0152Ketogenic Diet (KD) in AlcoholismParticipants currently recruited/enrolled18-125 YearsNIAAAAdult
17-AA-0114Brain Dopaminergic Signaling in Opioid use Disorders (OUD)Participants currently recruited/enrolled18-80 YearsNIAAAAdult
16-N-0114The Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques: An Investigator-Blinded StudyParticipants currently recruited/enrolled18-125 YearsNINDSAdult
16-N-0064Cholinergic Receptor Imaging in DystoniaCompleted Study; data analyses ongoing18-125 YearsNINDSAdult
16-N-0058Myalgic Encephalomyelitis/Chronic Fatigue SyndromeCompleted Study; data analyses ongoing18-60 YearsNINDSAdult
16-N-0055The Pathological Basis of MRI Signal Changes in Multiple Sclerosis: A Longitudinal In Vivo-to-Postmortem StudyParticipants currently recruited/enrolled18-125 YearsNINDSAdult
16-I-0126Genomic Response of Human Immune and Non-Immune Cells to GlucocorticoidsCompleted Study; data analyses ongoing18-64 YearsNIAIDAdult
16-I-0053A Multicenter Study of the Immunogenicity of Recombinant Vesicular Stomatitis Vaccine for Ebola-Zaire (rVSVdeltaG-ZEBOV GP) for Pre-Exposure Prophylaxis in Individuals at Potential Occupational Risk for Ebola Virus Exposure (PREPARE)No longer recruiting/follow-up only18-125 YearsNIAIDAdult
16-H-0144Impact of Elastin Mediated Vascular Stiffness on End OrgansParticipants currently recruited/enrolled3-85 YearsNHLBIAdult
16-H-0085Pilot Study to Evaluate the Effect of Fasting and Refeeding on T-Cell FateCompleted Study; data analyses ongoing21-37 YearsNHLBIT-Cell
16-EI-0169A Pilot Study to Investigate Ustekinumab (STELARA) for the Treatment of Active Sight-Threatening UveitisCompleted Study; data analyses ongoing18-125 YearsNEI Adult
16-EI-0090Natural History of Spinocerebellar Ataxia Type 7 (SCA7)Participants currently recruited/enrolled12-125 YearsNEI Adult
16-EI-0046Uveitis/Intraocular Inflammatory Disease Biobank (iBank)No longer recruiting/follow-up only8-125 YearsNEI Adult
16-E-0096Cytochrome P450 Epoxygenase Pathway Regulation of Macrophage FunctionParticipants currently recruited/enrolled18-65 YearsNIEHSAdult
16-DK-0125Evaluation of Adults with Endocrine-Related ConditionsParticipants currently recruited/enrolled18-100 YearsNIDDKAdult
16-DK-0068The Molecular, Cellular, and Genetic Characterization of Human Adipose Tissue and its Role in MetabolismParticipants currently recruited/enrolled18-125 YearsNIDDKAdult
16-DK-0038A Randomized, Double Blind, Placebo-Controlled Study to Assess Efficacy, Safety and Tolerability of ISIS 304801 in Patients with Partial Lipodystrophy with an Open-Label ExtensionCompleted Study; data analyses ongoing18-125 YearsNIDDKAdult
16-CC-0149Dopamine and Motor Learning in Cerebral PalsyParticipants currently recruited/enrolled5-25 YearsCC Adult
16-CC-0112Impact of Once-Weekly Rifapentine and Isoniazid on the Steady State Pharmacokinetics of Dolutegravir and Darunavir Boosted with Cobicistat in Healthy VolunteersCompleted Study; data analyses ongoing18-65 YearsCC Adult
16-CC-0056Analysis of A Tool to Assess Psycho Social Spiritual Healing: Cognitive InterviewingCompleted Study; data analyses ongoing18-125 YearsCC Adult
16-CC-0049A Phase II Study Using LC Bead LUMI Radio-Opaque Embolic Beads to Detect and Characterize the Vascularity of Hepatic Tumors During Treatment with Transarterial Embolization (TAE) Alone or Combined with Thermal AblationEnrolling by Invitation18-125 YearsCC Adult
16-C-0154A Phase I/II Trial of T Cell Receptor Gene Therapy Targeting HPV-16 E7 for HPV-Associated CancersParticipants currently recruited/enrolled18-125 YearsNCI Adult
16-C-0151Evaluation of the Natural History of and Specimen Banking for Patients with Tumors of the Central Nervous SystemParticipants currently recruited/enrolled18-125 YearsNCI Adult
16-C-0128A Phase I/II Study of Mesothelin-Targeted Immunotoxin LMB-100 Alone or in Combination with Nab-Paclitaxel in Participants with Previously Treated Metastatic and/ or Locally Advanced Pancreatic Ductal Adenocarcinoma and Mesothelin Expressing Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Adult
16-C-0107A Phase I/II Trial of EP0057, a Nanoparticle Camptothecin with Olaparib in Patients with Relapsed/Refractory Small Cell Lung, Bladder and Prostate CancersParticipants currently recruited/enrolled18-125 YearsNCI Adult
16-C-0097Phase 1 Trial of Panobinostat in Children with Diffuse Intrinsic Pontine GliomaCompleted Study; data analyses ongoing2-21 YearsNCI Adult
16-C-0094A Phase 1/2 Study of Baricitinib, a JAK1/2 Inhibitor, in Chronic Graft-Versus-Host Disease (cGVHD) after Allogeneic Hematopoietic Stem Cell Transplantation (SCT)No longer recruiting/follow-up only18-125 YearsNCI Adult
16-C-0092A Pilot Study of Local Ablative Therapy for Treatment of Oligoprogressive, EGFR-mutated, Non-Small Cell Lung Cancer (NSCLC) After Treatment with Osimertinib (AZD9291, Tagrisso)Completed Study; data analyses ongoing18-125 YearsNCI Adult
16-C-0076Prospective Screening for Patient Specific Genotypes and Phenotypes that Influence Drug Dosing and Trial Selection in Cancer PatientsEnrolling by Invitation18-125 YearsNCI Adult
16-C-0073A Phase 2 Study of Olaparib and Cediranib for the Treatment of Recurrent Ovarian CancerCompleted Study; data analyses ongoing18-125 YearsNCI Adult
16-C-0066Phase I Study of MK-3475 (Pembrolizumab) in Patients with Human Immunodeficiency Virus (HIV) and Relapsed/Refractory or Disseminated Malignant NeoplasmParticipants currently recruited/enrolled18-125 YearsNCI T-Cell
16-C-0060A Phase 1b/2 Study of alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Stem Cell TransplantationParticipants currently recruited/enrolled18-125 YearsNCI Adult
16-C-0054T Cells Expressing a Fully-human Anti- CD19 Chimeric Antigen Receptor for Treating B-cell MalignanciesNo longer recruiting/follow-up only18-73 YearsNCI T-Cell
16-C-0043Phase II Trial of the MEK1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate in Adults with Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform NeurofibromasNo longer recruiting/follow-up only18-125 YearsNCI Adult
16-C-0034A Phase II Trial of Oral Pazopanib plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) without Prior Bevacizumab Exposure and (B) after Failing Prior BevacizumabCompleted Study; data analyses ongoing18-125 YearsNCI Adult
16-C-0010Care of the Prostate Cancer Patient and Prospective Procurement of Prostate Cancer TissueParticipants currently recruited/enrolled18-125 YearsNCI Adult
16-C-0009Phase II Trial of Carboplatin and Bevacizumab for the Treatment of Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial and Spinal Cord Ependymoma in Adults: A Multi-Center TrialCompleted Study; data analyses ongoing18-125 YearsNCI Adult
16-C-0003Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesParticipants currently recruited/enrolled4-75 YearsNCI T-Cell
15-N-0175An Open-Label, Phase 1b Safety and Efficacy Trial of Periganglionic Resiniferatoxin for the Treatment of Intractable Pain due to Cancer-induced Bone PainRecruitment has not started18-150 YearsNINDSAdult
15-N-0156In Vivo Characterization of Inflammation with Ferumoxytol, an Ultrasmall Superparamagnetic Iron Oxide Nanoparticle, on 7 Tesla Magnetic Resonance ImagingCompleted Study; data analyses ongoing18-70 YearsNINDSAdult
15-N-0126HERV-K Suppression using Antiretroviral Therapy in Volunteers with Amyotrophic Lateral Sclerosis (ALS)No longer recruiting/follow-up only18-125 YearsNINDSAdult
15-N-0081A Study of Direct Brain Recording and Stimulation for Memory EnhancementEnrolling by Invitation18-65 YearsNINDSAdult
15-M-0188The Neurobiology of SuicideParticipants currently recruited/enrolled18-70 YearsNIMH Adult
15-M-0151An Investigation of the Antidepressant Effects of the Glycine Receptor Antagonist AV 101 (4-chlorokynurenine) in Major Depressive DisorderCompleted Study; data analyses ongoing18-65 YearsNIMH Adult
15-M-0066Influence on Plasticity of Brain TemperatureParticipants currently recruited/enrolled18-50 YearsNIMH Adult
15-I-0148A Phase I Study of Respiratory Syncytial Virus Human Challenge in Healthy Adult VolunteersCompleted Study; data analyses ongoing18-50 YearsNIAIDAdult
15-I-0131Xenodiagnosis after Antibiotic Treatment for Lyme Disease - Phase II StudyCompleted Study; data analyses ongoing18-125 YearsNIAIDAdult
15-H-0172A Pilot Phase II Study Using Ibrutinib and Short-Course Fludarabine in Previously Untreated Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)No longer recruiting/follow-up only18-125 YearsNHLBIT-Cell
15-H-0155Hereditary Parkinson Disease Natural History ProtocolCompleted Study; data analyses ongoing18-80 YearsNHLBIAdult
15-EI-0038A Phase I/IIa Study of RS1 Ocular Gene Transfer for X-linked RetinoschisisNo longer recruiting/follow-up only18-125 YearsNEI Adult
15-E-0058Natural History of Asthma with Longitudinal Environmental SamplingParticipants currently recruited/enrolled18-60 YearsNIEHSAdult
15-DK-0143Investigation of Viral Kinetics, Interferon Stimulated Genes (ISGs) and mirRNA Among Subjects Infected with Different Hepatitis C Virus Genotypes During Therapy with Sofosbuvir and GS-5816Completed Study; data analyses ongoing18-80 YearsNIDDKAdult
15-DK-0119Thyroid Hormone to Induce Non-Insulin Mediated Glucose Disposal in Patients with Insulin Receptor MutationsCompleted Study; data analyses ongoing12-65 YearsNIDDKAdult
15-DK-0082Mechanisms Associated with Favorable Response to Peginterferon-Alpha Add-on Therapy Following Long-term Nucleos(t)ide Analogue Treatment in Patients with Chronic Hepatitis BCompleted Study; data analyses ongoing18-125 YearsNIDDKAdult
15-DK-0079Observational Study of Hepatitis B Virus (HBV) in Patients Coinfected with Human Immunodeficiency Virus (HIV)Completed Study; data analyses ongoing18-125 YearsNIDDKAdult
15-D-0129Open-Label, Dose-Escalation Study Evaluating the Safety of a Single Administration of an Adeno-Associated Virus Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in Individuals with Irradiation-Induced Parotid Salivary Hypofunction.Participants currently recruited/enrolled18-125 YearsNIDCRAdult
15-D-0051Characterization of Diseases with Salivary Gland InvolvementParticipants currently recruited/enrolled4-125 YearsNIDCRAdult
15-CC-0091Pulmonary Effects of Bronchial Segmental Endotoxin Instillation in HumansClinical hold/Recruitment or enrollment suspended18-45 YearsCC Adult
15-C-0195Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals with Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)Participants currently recruited/enrolled5-125 YearsNCI Adult
15-C-0160A Phase I Study of Cabozantinib Plus Nivolumab (CaboNivo) Alone or in Combination with Ipilimumab (CaboNivoIpi) in Patients with Advanced/Metastatic Urothelial Carcinoma and other Genitourinary TumorsNo longer recruiting/follow-up only18-125 YearsNCI Adult
15-C-0150A Phase I/II Trial of Topotecan with VX-970 (M6620), an ATR Kinase Inhibitor in Small Cell CancersNo longer recruiting/follow-up only18-125 YearsNCI Adult
15-C-0145Phase I/II Study of the Anti-Programmed Death Ligand-1 Antibody Durvalumab (MEDI4736) in Combination with Olaparib and/or Cediranib for Advanced Solid Tumors and Advanced or Recurrent Ovarian, Triple Negative Breast, Lung, Prostate and Colorectal CancersParticipants currently recruited/enrolled18-125 YearsNCI Adult
15-C-0142Acceptance and Commitment Training for Adolescents and Adults with Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain: A Phase III Clinical TrialCompleted Study; data analyses ongoing16-59 YearsNCI Adult
15-C-0141Gene Therapy Follow up Protocol for Subjects Previously Enrolled in CAR T-Cell StudiesEnrolling by Invitation18-125 YearsNCI T-Cell
15-C-0138Phase I Study of Ipilimumab, Nivolumab, and the Combination in Patients with Newly Diagnosed GlioblastomaCompleted Study; data analyses ongoing18-125 YearsNCI Adult
15-C-0116Phase I Trial of 4'-thio-2'-deoxycytidine (TdCyd) in Patients With Advanced Solid TumorsClinical hold/Recruitment or enrollment suspended18-125 YearsNCI Adult
15-C-0099A Phase 1, Open-Label, Dose-Escalation Study of SNX-5422 and Everolimus in Subjects with Neuroendocrine TumorsCompleted Study; data analyses ongoing18-100 YearsNCI Adult
15-C-0093Phase I Trial of Turalio(R) (pexidartinib, PLX3397) in Children and Young Adults with Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN)Participants currently recruited/enrolled3-35 YearsNCI Adult
15-C-0087Care of the Urothelial Cancer Patient and Prospective Collection of Biospecimens from Healthy Volunteers and Urothelial Cancer PatientsParticipants currently recruited/enrolled18-125 YearsNCI Adult
15-C-0086Phase I Trial of the Combination of Nilotinib and Paclitaxel in Adults and Pediatric Patients with Refractory Solid TumorsParticipants currently recruited/enrolled12-120 YearsNCI Adult
15-C-0078Safety and Feasibility of Stem Cell Gene Transfer Following R-EPOCH for Non-Hodgkin Lymphoma in AIDS Patients Using Peripheral Blood Stem/Progenitor Cells Treated with a Lentivirus Vector-Encoding Multiple Anti-HIV RNAsNo longer recruiting/follow-up only18-65 YearsNCI Adult
15-C-0076A Pilot Study of Long Term TARP Vaccination Using A Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Previously Vaccinated Men on NCI 09-C-0139Completed Study; data analyses ongoing18-125 YearsNCI T-Cell
15-C-0067A Phase I/II Open Label, Dose Escalation Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell TransplantationParticipants currently recruited/enrolled18-125 YearsNCI Adult
15-C-0029Phase I Dose Escalation Study of Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults with Recurrent or Refractory CD22-expressing B Cell MalignanciesParticipants currently recruited/enrolled3-39 YearsNCI Adult
15-AR-0165Study of the Natural History, Pathogenesis and Outcome of Melorheostosis - a Rare Osteosclerotic DiseaseParticipants currently recruited/enrolled18-90 YearsNIAMSAdult
15-AR-0144Studies of Dermatologic Diseases-Biospecimen Acquisition ProtocolParticipants currently recruited/enrolled2-125 YearsNIAMSAdult
15-AR-0060The Role of PPAR-gamma Agonists in immunomodulation and Vascular Prevention in SLE (PPAR-SLE)Completed Study; data analyses ongoing18-99 YearsNIAMSAdult
15-AG-0063The Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)Participants currently recruited/enrolled20-125 YearsNIA Adult
15-AA-0186Development of Neuroimaging Methods to Assess the Neurobiology of AddictionParticipants currently recruited/enrolled18-125 YearsNIAAAAdult
15-AA-0127(Epi)genetic Modulators of Fear Extinction in Alcohol DependenceParticipants currently recruited/enrolled21-65 YearsNIAAAAdult
14-N-0086Deep Brain Stimulation Therapy in Movement DisordersParticipants currently recruited/enrolled18-125 YearsNINDSAdult
14-N-0083Neural Basis of Decision Making Deficits in Traumatic Brain InjuryParticipants currently recruited/enrolled18-60 YearsNINDSAdult
14-N-0061Noninvasive Pre-surgical Evaluation of Patients with Focal Epilepsy and Establishment of a Normative Imaging DatabaseParticipants currently recruited/enrolled8-65 YearsNINDSAdult
14-I-0206Novel Genetic Disorders of the Immune SystemParticipants currently recruited/enrolled0-99 YearsNIAIDAdult
14-I-0194Screening of Volunteers for Clinical Trials of Investigational or Licensed Vaccines or Antiviral ProductsParticipants currently recruited/enrolled18-65 YearsNIAIDAdult
14-I-0124PET Imaging and Lymph Node Assessment of IRIS in Persons With AIDSParticipants currently recruited/enrolled18-125 YearsNIAIDAdult
14-I-0081A Phase 2a Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Subcutaneous Benralizumab (MEDI-563) in Reducing Eosinophilia in Subjects with Hypereosinophilic Syndrome (HES)No longer recruiting/follow-up only18-75 YearsNIAIDAdult
14-I-0063An Open-Label, Proof-of-Concept Study to Evaluate the Safety and Efficacy of Dexpramipexole (KNS-760704) in Subjects with Hypereosinophilic SyndromeNo longer recruiting/follow-up only18-125 YearsNIAIDAdult
14-I-0039Elite Controller and ART-Treated HIV+ Statin Versus ASA Treatment Intervention StudyCompleted Study; data analyses ongoing18-125 YearsNIAIDAdult
14-I-0009Characterization and Management of Patients with HIV-1 Infection Who Experience Virologic Failure Despite Combination Antiretroviral TherapyCompleted Study; data analyses ongoing18-100 YearsNIAIDAdult
14-HG-0071Clinical and Basic Investigations into Known and Suspected Congenital Disorders of GlycosylationParticipants currently recruited/enrolled1-80 YearsNHGRIAdult
14-HG-0055Study on Moebius Syndrome and Other Congenital Facial Weakness DisordersCompleted Study; data analyses ongoing2-80 YearsNHGRIAdult
14-HG-0048Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST)Participants currently recruited/enrolled21-125 YearsNHGRIT-Cell
14-H-0188Prospective Evaluation of Next Generation CT ReconstructionParticipants currently recruited/enrolled18-99 YearsNHLBIAdult
14-H-0155A Phase 1/2 Study Evaluating Gene Therapy by Transplantation of Autologous CD34+ Stem Cells Transduced Ex Vivo with the LentiGlobin BB305 Lentiviral Vector in Subjects with Severe Sickle Cell DiseaseNo longer recruiting/follow-up only18-50 YearsNHLBIAdult
14-CC-0201A Randomized Controlled Trial to Determine the Effectiveness of a Stress Reduction Intervention in Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) RecipientsCompleted Study; data analyses ongoing18-125 YearsCC Adult
14-CC-0143Sleep Disturbance and Relapse in Individuals with Alcohol Dependence: An Exploratory Mixed Methods StudyCompleted Study; data analyses ongoing18-125 YearsCC Adult
14-C-0161Phase I Trial of the Combination of Bortezomib and Clofarabine in Adults with Refractory Solid Tumors, Lymphomas, or Myelodysplastic SyndromesParticipants currently recruited/enrolled18-125 YearsNCI Adult
14-C-0131A Phase II, Open-Label Study in Patients With BRAF V600E-Mutated Rare Cancers With Several Histologies to Investigate the Clinical Efficacy and Safety of the Combination Therapy of Dabrafenib and TrametinibCompleted Study; data analyses ongoing18-125 YearsNCI Adult
14-C-0116A Randomized Controlled Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated with Cranial Radiation for Brain TumorsParticipants currently recruited/enrolled8-125 YearsNCI Adult
14-C-0105Tissue Procurement and Natural History Study of Patients with Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial TumorsParticipants currently recruited/enrolled18-125 YearsNCI Adult
14-C-0104A Phase II Study Using Autologous Young Tumor-Infiltrating Lymphocytes Derived from Patients with Non-Small Cell Lung Cancer Following Non-Myeloablative Lymphocyte Depleting Preparative RegimenParticipants currently recruited/enrolled18-70 YearsNCI Adult
14-C-0079An Exploratory Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults with Cancer and Other Chronic IllnessesParticipants currently recruited/enrolled18-125 YearsNCI Adult
14-C-0059A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults with GD2+ Solid TumorsCompleted Study; data analyses ongoing1-35 YearsNCI Adult
14-C-0056Collection of Blood from Patients with Ovarian, Primary Peritoneal or Fallopian Tube CancerCompleted Study; data analyses ongoing18-125 YearsNCI T-Cell
14-C-0052A Phase I/II Study of the Treatment of Metastatic Cancer that Expresses MAGE-A3 Using Lymphodepleting Conditioning Followed by Infusion of HLA-DP0401/0402 Restricted Anti-MAGE-A3 TCR-Gene Engineered Lymphocytes and AldesleukinCompleted Study; data analyses ongoing18-70 YearsNCI Adult
14-C-0036A Randomized, Prospective, Phase II Study to Determine the Efficacy of Bacillus Calmette-Guerin (BCG) Given in Combination with PANVAC[TM] Versus BCG Given Alone in Adults with High Grade Non-Muscle Invasive Bladder Cancer (NMIBC) Who Failed at Least 1 ICompleted Study; data analyses ongoing18-125 YearsNCI Adult
14-C-0007Phase II Trial of the Gamma-Secretase Inhibitor Nirogacestat (PF-03084014) in Adults with Desmoid Tumors/Aggressive FibromatosisNo longer recruiting/follow-up only18-125 YearsNCI Adult
14-C-0001Phase II Study of Axitinib (AG-013736) with Evaluation of the VEGF-pathway in Metastatic, Recurrent or Primary Unresectable Pheochromocytoma/ParagangliomaCompleted Study; data analyses ongoing18-125 YearsNCI Adult
14-AA-0192Brain Inflammation and Function in AlcoholismCompleted Study; data analyses ongoing30-75 YearsNIAAAAdult
14-AA-0187Dopamine Rhythms in Health and AddictionClinical hold/Recruitment or enrollment suspended21-55 YearsNIAAAAdult
14-AA-0181NIAAA Natural History ProtocolParticipants currently recruited/enrolled18-100 YearsNIAAAAdult
14-AA-0144Reliability Of The Human Brain ConnectomeParticipants currently recruited/enrolled18-125 YearsNIAAAAdult
14-AA-0080Characterization Imaging Instruments for Addiction Neuroimaging AssessmentsParticipants currently recruited/enrolled18-125 YearsNIAAAAdult
14-AA-0066Behavioral and Functional Task Development, Implementation, and TestingParticipants currently recruited/enrolled18-65 YearsNIAAAAdult
13-N-0188Natural History and Biomarkers of C9ORF72 Amyotrophic Lateral Sclerosis and Frontotemporal DementiaCompleted Study; data analyses ongoing18-125 YearsNINDSAdult
13-N-0165Electrical Impedance Myography: Natural History Studies in Neuromuscular Disorders and Healthy VolunteersParticipants currently recruited/enrolled2-125 YearsNINDSAdult
13-N-0135Pilot Study of Raltegravir, an Integrase Inhibitor, in Human T-Cell Lymphotrophic Virus-1(HTLV-1) Associated Myelopathy, Tropical Spastic Paraparesis (HAM/TSP)Completed Study; data analyses ongoing18-125 YearsNINDST-Cell
13-M-0028Diagnosis of Childhood-onset Behavioral Disorders, Neuropsychiatric Disorders and Neurodevelopmental DisordersParticipants currently recruited/enrolled0-99 YearsNIMH Adult
13-I-0172Phase I Study of the Safety of a Replication-Defective Herpes Simplex Virus-2 Vaccine, HSV529, in Adults Aged 18 to 40 Years With or Without HSV InfectionCompleted Study; data analyses ongoing18-40 YearsNIAIDAdult
13-H-0194Inflammatory Characterization of Known or Possible Cardiovascular DiseasesNo longer recruiting/follow-up only18-125 YearsNHLBIAdult
13-H-0183Cardiovascular Health and Needs Assessment in Washington D.C. - Development of a Community-Based Behavioral Weight Loss InterventionParticipants currently recruited/enrolled19-85 YearsNHLBIAdult
13-H-0116A Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units (CBUs) Manufactured by the National Cord Blood Program (NCBP) and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult PatientsParticipants currently recruited/enrolled4-125 YearsNHLBIAdult
13-E-0015Environmental Risk Factors for the Development of Myositis in Military PersonnelNo longer recruiting/follow-up only18-125 YearsNIEHSAdult
13-DK-0200The Mechanism of Human Non-Shivering Thermogenesis and Basal Metabolic RateParticipants currently recruited/enrolled18-35 YearsNIDDKAdult
13-D-0033Diagnosis and Treatment of Patients in Need of Third Molar Removal and Oral Specimen AcquisitionParticipants currently recruited/enrolled16-50 YearsNIDCRAdult
13-C-0202Tissue Procurement and Natural History Study of Patients with Malignant Mesothelioma and Other Mesothelin Expressing CancersParticipants currently recruited/enrolled2-125 YearsNCI Adult
13-C-0176Tumor, Normal Tissue and Specimens from Patients Undergoing Evaluation or Surgical Resection of Solid TumorsParticipants currently recruited/enrolled2-125 YearsNCI Adult
13-C-0175A Phase II Protocol for Subjects with Stage T1 Bladder Cancer to Evaluate Selective Bladder Preserving Treatment by Radiation Therapy Concurrent with Radio-sensitizing Chemotherapy following a Thorough Transurethral Surgical Re-StagingCompleted Study; data analyses ongoing18-125 YearsNCI Adult
13-C-0152A Phase I Study of Autologous Activated Natural Killer (NK) Cells +/- rhIL15 in Children and Young Adults with Refractory Solid TumorsCompleted Study; data analyses ongoing2-29 YearsNCI Adult
13-C-0095A Phase 2 Study of GI-6207 in Patients with Recurrent Medullary Thyroid CancerCompleted Study; data analyses ongoing18-125 YearsNCI T-Cell
13-C-0016A Phase I Study of an Adenoviral Transduced Autologous Dendritic Cell Vaccine Expressing Human HER2/neu ECTM in Adults with Tumors with 1-3+ HER2/neu ExpressionCompleted Study; data analyses ongoing18-125 YearsNCI Adult
13-AG-0034Phase I, Double-Blind, Placebo-Controlled, Ascending, Single-Dose, Safety, Tolerability and Pharmacokinetic Study of Bisnorcymserine (BNC), a Highly Selective Inhibitor of Butyrylcholinesterase, in Healthy Adult VolunteersCompleted Study; data analyses ongoing55-125 YearsNIA Adult
12-HG-0202The Neurobehavioral, Environmental and Genetic Factors Impacting the Clinical Course of Attention Deficit Hyperactivity DisorderParticipants currently recruited/enrolled3-125 YearsNHGRIAdult
12-HG-0022Inherited Diseases, Caregiving, and Social NetworksCompleted Study; data analyses ongoing18-125 YearsNHGRIAdult
12-H-0141Prospective Evaluation of New Techniques in Radiation Reduction for Cardiovascular Computed Tomographic AngiographyParticipants currently recruited/enrolled18-125 YearsNHLBIAdult
12-H-0064A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients with Hematologic Malignancies and Other IndicationsParticipants currently recruited/enrolled4-75 YearsNHLBIAdult
12-EI-0203Natural History of ABCA4-Related RetinopathiesNo longer recruiting/follow-up only12-125 YearsNEI Adult
12-EI-0042NEI Intramural Biorepository for Retinal DiseasesParticipants currently recruited/enrolled2-125 YearsNEI Adult
12-E-0061The Role of the Functionally Relevant Single Nucleotide Polymorphisms CYP2J2 -50G>T (CYP2J2 7) and EPHX2 9846A>G (EPHX2 K55R) in Human Endothelial FunctionCompleted Study; data analyses ongoing18-65 YearsNIEHSAdult
12-E-0050The Role of Gonadotropin Pulsations in the Regulation of Puberty and FertilityParticipants currently recruited/enrolled14-125 YearsNIEHSAdult
12-E-0049The Molecular Basis of Inherited Reproductive DisordersParticipants currently recruited/enrolled0-125 YearsNIEHSAdult
12-DK-0097Energy Expenditure Responses to Different TemperaturesParticipants currently recruited/enrolled18-75 YearsNIDDKAdult
12-DK-0071Combination Entecavir and Peginterferon Therapy in HBeAg-Positive Immune-Tolerant Adults with Chronic Hepatitis BCompleted Study; data analyses ongoing18-40 YearsNIDDKAdult
12-D-0100Oral Microbial and Immunological Characterization of Patients with Immune DysfunctionParticipants currently recruited/enrolled7-125 YearsNIDCRAdult
12-C-0178Longitudinal Assessment and Natural History Study of Children and Adults with MEN2A or MEN2B with or without Medullary Thyroid CarcinomaParticipants currently recruited/enrolled0-125 YearsNCI Adult
12-C-0175Prospective Procurement of Solid Tumor Tissue to Identify Novel Therapeutic TargetsCompleted Study; data analyses ongoing18-125 YearsNCI Adult
12-C-0160Validation of the English Version of the Pain Interference Index and the Pain Rating Scale in Children, Adolescents, and Adults with Chronic Illness and their ParentsParticipants currently recruited/enrolled18-125 YearsNCI Adult
12-C-0112Phase I Study of T Cells Expressing an Anti-CD19 Chimeric Receptor in Children and Young Adults with B Cell MalignanciesCompleted Study; data analyses ongoing1-30 YearsNCI Adult
12-C-0107Carfilzomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma: a Clinical and Correlative Pilot StudyNo longer recruiting/follow-up only18-125 YearsNCI Adult
11-N-0051Surgery as a Treatment for Medically Intractable EpilepsyParticipants currently recruited/enrolled8-125 YearsNINDSAdult
11-M-0251A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying PubertyParticipants currently recruited/enrolled7-35 YearsNIMH Adult
11-I-0007Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age with X-Linked Severe Combined ImmunodeficiencyClinical hold/Recruitment or enrollment suspended2-40 YearsNIAIDAdult
11-HG-0218A Natural History Study of Patients with GNE Myopathy and GNE-Related DiseasesParticipants currently recruited/enrolled4-80 YearsNHGRIAdult
11-HG-0110Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora PopulationsEnrolling by Invitation18-125 YearsNHGRIAdult
11-E-0072Environmental Risk Factors for the Anti-Synthetase SyndromeParticipants currently recruited/enrolled2-100 YearsNIEHSAdult
11-D-0172The Pathogenesis and Natural History of Sjogren's SyndromeParticipants currently recruited/enrolled16-125 YearsNIDCRAdult
11-CC-0120Stereophotogrammetry of the Torso in Healthy Individuals and Patients with Scoliosis, Chest Wall Deformations, or ObesityCompleted Study; data analyses ongoing2-125 YearsCC Adult
11-C-0161A Phase I/II Study of the Mitogen Activated Protein Kinase Kinase (MEK) 1 Inhibitor Selumetinib (AZD6244; Hydrogen Sulfate in Children with Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)No longer recruiting/follow-up only2-18 YearsNCI Adult
11-C-0136Multi-Institutional Prospective Pilot Study of Lupron to Enhance Lymphocyte Immune Reconstitution Following Allogeneic Bone Marrow Transplantation in Post-Pubertal Children and Adults with Molecular Imaging EvaluationCompleted Study; data analyses ongoing2-55 YearsNCI Adult
11-C-0061Phase I Trial of Z-Endoxifen in Adults with Refractory Hormone Receptor-Positive Breast Cancer, Desmoid Tumors, Gynecologic Tumors, or other Hormone Receptor-Positive Solid TumorsNo longer recruiting/follow-up only18-125 YearsNCI Adult
10-M-0027Cognitive Neuroscience of Autism Spectrum DisordersParticipants currently recruited/enrolled5-89 YearsNIMH Adult
10-I-0148Natural History of Severe Allergic Inflammation and ReactionsParticipants currently recruited/enrolled2-80 YearsNIAIDAdult
10-I-0109VRC 900: Evaluation of Tissue-Specific Immune Responses in Adults 18 Years of Age and OlderParticipants currently recruited/enrolled18-125 YearsNIAIDAdult
10-H-0154Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused with a Reduced Dose of Non-Mobilized Donor T-CellsParticipants currently recruited/enrolled4-80 YearsNHLBIT-Cell
10-E-0063Sample Collection Registry for Quality Control of Biological and Environmental Specimens and Assay Development and TestingCompleted Study; data analyses ongoing18-125 YearsNIEHSAdult
10-CC-0150Effects of Rapid-Resisted Exercise on Ambulatory Adults with Traumatic Brain InjuryCompleted Study; data analyses ongoing18-44 YearsCC Adult
10-C-0166A Phase II Study Using Short-Term Cultured, Autologous Tumor-Infiltrating Lymphocytes Following a Lymphodepleting Regimen in Metastatic Cancers Plus the Administration of PembrolizumabParticipants currently recruited/enrolled18-72 YearsNCI Adult
10-C-0086Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological StudiesParticipants currently recruited/enrolled0-125 YearsNCI Adult
10-C-0066A Study of Hairy Cell and other Leukemias with a Focus on Recombinant Immunotoxins for Cancer TreatmentParticipants currently recruited/enrolled18-125 YearsNCI Adult
10-C-0056A Phase I Study of Indenoisoquinolines LMP400 and LMP776 in Adults With Relapsed Solid Tumors and LymphomasCompleted Study; data analyses ongoing18-125 YearsNCI Adult
09-I-0232FLU 003 Plus: An International Observational Study to Characterize Adults Who Are Hospitalized with Influenza or Other Targeted Respiratory VirusesParticipants currently recruited/enrolled18-125 YearsNIAIDAdult
09-I-0102Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ LymphocytopeniaParticipants currently recruited/enrolled18-125 YearsNIAIDAdult
09-I-0013Biomarkers of Inflammation, Coagulation, and Endothelial Function in HIV-Infected AdultsEnrolling by Invitation18-100 YearsNIAIDAdult
09-H-0239Cellular and Molecular Characterization of the Immune Response in Healthy NIH Employees at Baseline, and After Immunization with the H1N1 or Seasonal Influenza VaccinesCompleted Study; data analyses ongoing18-125 YearsNHLBIAdult
09-C-0100A Pilot Study of High Dose Rate Brachytherapy in The Radiation Oncology BranchParticipants currently recruited/enrolled18-125 YearsNCI Adult
09-C-0024A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents and Young AdultsCompleted Study; data analyses ongoing12-26 YearsNCI Adult
09-C-0019A Phase I Study of Dasatinib in Combination with Bevacizumab in Advanced Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Adult
08-HG-0059Studies of Skin Microflora in Healthy Individuals and Atopic Dermatitis PatientsParticipants currently recruited/enrolled2-125 YearsNHGRIAdult
08-DK-0173A Trial of Segmental Stiffening Wires to Improve the Efficiency and Patient Tolerability of ColonoscopyCompleted Study; data analyses ongoing40-80 YearsNIDDKAdult
08-DK-0004High Sensitivity Screening of Compound Libraries to Discover a Drug for the Treatment of Sickle Cell DiseaseParticipants currently recruited/enrolled18-100 YearsNIDDKAdult
08-C-0130A Phase II Trial of Peginterferon alfa-2b (PEG-Intron) for Neurofibromatosis Type 1 Related Unresectable, Symptomatic or Life-Threatening Plexiform NeurofibromasCompleted Study; data analyses ongoing0-21 YearsNCI Adult
08-C-0079Natural History Study and Longitudinal Assessment of Children, Adolescents, and Adults with Neurofibromatosis Type 1No longer recruiting/follow-up only0-125 YearsNCI Adult
08-C-0020A Phase II Study of ZD6474 (Vandetanib) in Patients with Von Hippel Lindau Disease and Renal TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Adult
07-HG-0002ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot StudyNo longer recruiting/follow-up only6-95 YearsNHGRIAdult
07-E-0012Rituximab in the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)Completed Study; data analyses ongoing2-125 YearsNIEHSAdult
07-DK-0115Natural History of Type 2 Diabetes Mellitus in Children and Young AdultsCompleted Study; data analyses ongoing8-25 YearsNIDDKAdult
07-DK-0077Study of the Phenotype of Overweight and Obese AdultsParticipants currently recruited/enrolled18-100 YearsNIDDKAdult
07-D-0016Effects of PTH Replacement on Bone in HypoparathyroidismCompleted Study; data analyses ongoing18-70 YearsNIDCRAdult
07-C-0110Analysis of Stored Data Collected from Individuals Administered Neurobehavioral Assessments on IRB-Approved ProtocolsEnrolling by Invitation0-125 YearsNCI Adult
06-I-0015Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell DeathParticipants currently recruited/enrolled0-125 YearsNIAIDT-Cell
06-CH-0011Natural History Study of Patients with Excess AndrogenParticipants currently recruited/enrolled0-99 YearsNICHDAdult
06-C-0213Tissue Procurement Protocol for the Developmental Therapeutics Clinic, National Cancer Institute (NCI)Participants currently recruited/enrolled0-125 YearsNCI Adult
05-M-0144MRS (Magnetic Resonance Spectroscopy) Measurement of Glutamate and GABA Metabolism in BrainParticipants currently recruited/enrolled18-65 YearsNIMH Adult
05-H-0242A Pilot Study of Alemtuzumab (Campath) in Patients with Relapsed or Refractory Severe Aplastic AnemiaCompleted Study; data analyses ongoing2-110 YearsNHLBIT-Cell
04-I-0286A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease ProgressionParticipants currently recruited/enrolled1-100 YearsNIAIDAdult
04-HG-0211Analysis of Specimens from Individuals with Pulmonary FibrosisParticipants currently recruited/enrolled18-125 YearsNHGRIAdult
04-C-0281Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host DiseaseParticipants currently recruited/enrolled1-125 YearsNCI Adult
04-C-0275Targeted Oncolytic Virotherapy and Natural History Study of KSHV-Associated Multicentric Castleman's Disease with Laboratory and Clinical Correlates of Disease ActivityNo longer recruiting/follow-up only18-125 YearsNCI Adult
03-M-0211Family Study of Affective and Anxiety Spectrum DisordersParticipants currently recruited/enrolled7-125 YearsNIMH Adult
03-H-0170Nonmyeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation For Severe Congenital Anemias Including Sickle Cell Disease (SCD) and Beta-ThalassemiaParticipants currently recruited/enrolled2-125 YearsNHLBIAdult
03-C-0278A Comparative Study of Pediatric CNS Tumor Activity as Assessed by 18F-FDG PET Imaging and Proton Magnetic Resonance Spectroscopic Imaging (1H-MRSI)Completed Study; data analyses ongoing1-21 YearsNCI Adult
03-C-0277Cell Harvest and Preparation for Surgery Branch Adoptive Cell Therapy ProtocolsEnrolling by Invitation18-125 YearsNCI Adult
03-AR-0173Studies of Natural History, Pathogenesis, and Outcomes in Autoimmune and Inflammatory Diseases Including Juvenile DermatomyositisParticipants currently recruited/enrolled2-125 YearsNIAMSAdult
02-M-0021Characterization and Pathophysiology of Severe Mood and Behavioral Dysregulation in Children and YouthParticipants currently recruited/enrolled7-60 YearsNIMH Adult
02-I-0202Leukapheresis Procedures to Obtain Plasma and Lymphocytes for Research Studies on Antiretroviral-Naive HIV-Infected PatientsParticipants currently recruited/enrolled18-125 YearsNIAIDAdult
02-I-0147Genetic Studies of Chronic Active Epstein-Barr Virus InfectionParticipants currently recruited/enrolled1-125 YearsNIAIDAdult
02-I-0086Evaluation of Viral Factors and Immune Parameters to Study HIV-Specific ImmunityParticipants currently recruited/enrolled18-125 YearsNIAIDAdult
02-I-0055Evaluation, Treatment, and Follow-up of Patients with Lyme DiseaseParticipants currently recruited/enrolled2-125 YearsNIAIDAdult
02-HG-0107Natural History of Glycosphingolipid Storage Disorders and Glycoprotein DisordersParticipants currently recruited/enrolled0-125 YearsNHGRIAdult
01-M-0254The Evaluation of Patients with Mood and Anxiety Disorders and Healthy VolunteersParticipants currently recruited/enrolled3-99 YearsNIMH Adult
01-M-0232Positron Emission Tomography (PET) Scanning in Dopamine Disorders: Parkinson's Disease and SchizophreniaParticipants currently recruited/enrolled18-90 YearsNIMH Adult
01-M-0192Fluoxetine's Effects on Attention and Emotional Memory in Anxious and Depressed Youth and AdultsParticipants currently recruited/enrolled8-65 YearsNIMH Adult
01-HG-0109Natural History Study of the Clinical and Molecular Manifestations of Smith-Magenis Syndrome (SMS)No longer recruiting/follow-up only0-125 YearsNHGRIAdult
01-H-0088Determining the Prevalence and Prognosis of Secondary Pulmonary Hypertension in Adult Patients with Sickle Cell AnemiaCompleted Study; data analyses ongoing18-125 YearsNHLBIAdult
01-DC-0228Clinical and Molecular Analysis of Enlarged Vestibular AqueductsCompleted Study; data analyses ongoing0-99 YearsNIDCDAdult
01-CC-0231A Prospective Study of Transfusion-Transmitted InfectionsCompleted Study; data analyses ongoing0-125 YearsCC Adult
01-C-0038Collection of Blood, Bone Marrow, Tumor, or Tissue Samples from Patients with HIV Infection, KSHV Infection, Viral-Related Pre-Malignant Lesions, and/or CancerParticipants currently recruited/enrolled18-125 YearsNCI Adult
00-N-0082Characterization of Brain Morphology and Activity Using Functional and Anatomical MRI ContrastParticipants currently recruited/enrolled18-125 YearsNINDSAdult
00-N-0043Clinical and Molecular Manifestations of Inherited Neurological DisordersParticipants currently recruited/enrolled2-125 YearsNINDSAdult
00-HG-0141Clinical, Biochemical, and Molecular Investigations into AlkaptonuriaParticipants currently recruited/enrolled2-125 YearsNHGRIAdult
00-DK-0107Search for Novel Methods to Detect Acute Renal FailureParticipants currently recruited/enrolled3-125 YearsNIDDKAdult
00-CH-0136A Trial of Pamidronate in Children with Osteogenesis ImperfectaCompleted Study; data analyses ongoing2-17 YearsNICHDAdult
99-CC-0168Collection and Distribution of Blood Components from Healthy Donors for In Vitro Research UseParticipants currently recruited/enrolled18-125 YearsCC Adult
99-C-0128Evaluation for NCI Surgery Branch Clinical Research ProtocolsParticipants currently recruited/enrolled18-125 YearsNCI Adult
97-I-0096Evaluation, Treatment, and Monitoring of Patients With Known or Suspected Parasitic InfectionParticipants currently recruited/enrolled3-125 YearsNIAIDAdult
97-HG-0192Genetic Studies in the Amish and MennonitesCompleted Study; data analyses ongoing18-125 YearsNHGRIAdult
97-CH-0064Evaluation and Intervention for Ambulation, Growth, and Basilar Invagination in Osteogenesis ImperfectaCompleted Study; data analyses ongoing0-10 YearsNICHDAdult
96-H-0100Role of Genetic Factors in the Pathogenesis of Lung DiseaseParticipants currently recruited/enrolled2-90 YearsNHLBIAdult
96-CH-0033An Open, Randomized, Long-Term Clinical Trial of Flutamide, Testolactone, and Reduced Hydrocortisone Dose vs. Conventional Treatment of Children with Congenital Adrenal HyperplasiaNo longer recruiting/follow-up only2-18 YearsNICHDAdult
95-HG-0193Clinical and Basic Investigations into Hermansky-Pudlak SyndromeParticipants currently recruited/enrolled0-125 YearsNHGRIAdult
94-I-0073Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and GranulocytesParticipants currently recruited/enrolled18-70 YearsNIAIDAdult
94-E-0165Studies in the Natural History and Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory MyopathiesParticipants currently recruited/enrolled2-100 YearsNIEHSAdult
93-M-0170Regional Cerebral Blood Flow Studies of Object Perception, Identification, Localization, and MemoryParticipants currently recruited/enrolled18-65 YearsNIMH Adult
93-I-0106Cryptococcosis in Previously Healthy AdultsParticipants currently recruited/enrolled18-125 YearsNIAIDAdult
93-I-0086Evaluation and Long-Term Follow-Up of Patients with Acute or Chronic Inflammatory DisordersEnrolling by Invitation2-125 YearsNIAIDAdult
93-I-0063Study of the Immunopathogenesis, Natural History, and Genetics of Autoimmune Lymphoproliferative Syndrome (ALPS) Associated with an Expansion of CD4-8-/TCR alpha/beta+ T CellsParticipants currently recruited/enrolled0-99 YearsNIAIDAdult
93-C-0133Dose-Adjusted EPOCH Chemotherapy and Rituximab (CD20+) in Adults and Children with Previously Untreated Patients with Aggressive Non-Hodgkin's LymphomaNo longer recruiting/follow-up only12-125 YearsNCI Adult
92-CH-0034Studies of Growth Deficiency and Growth Hormone Treatment in Children with Osteogenesis Imperfecta Types III and IVCompleted Study; data analyses ongoing3-16 YearsNICHDAdult
89-I-0158Studies of Immune Regulation in Patients with Common Variable Immunodeficiency and Related Humoral Immunodeficiency SyndromesParticipants currently recruited/enrolled2-125 YearsNIAIDAdult
85-H-0105Cardiovascular Evaluation of Homozygous Familial HypercholesterolemiaCompleted Study; data analyses ongoing2-70 YearsNHLBIAdult
83-C-0022Psychological Benefits of a Normalized Camping Experience for Children with CancerParticipants currently recruited/enrolled7-25 YearsNCI Adult
82-I-0183A Natural History Study of the Immune Regulation of Idiopathic Inflammatory Bowel Diseases: Crohn's Disease, Ulcerative Colitis, and Other Inflammatory Conditions of the GutParticipants currently recruited/enrolled0-75 YearsNIAIDAdult
81-I-0164Procedures to Obtain Plasma, Lymphocytes, or Other Specimens for Research StudiesParticipants currently recruited/enrolled18-125 YearsNIAIDAdult
80-M-0083Bipolar Genetics: A Collaborative StudyParticipants currently recruited/enrolled18-125 YearsNIMH Adult
76-DK-0006Natural History of Disorders of Insulin ResistanceParticipants currently recruited/enrolled0-125 YearsNIDDKAdult
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