Department of Health and Human Services
National Institutes of Health
Toggle navigation
Search
Home
About the Clinical Center
Clinical Trials & You
Participate in a Study
Referring a Patient
How to Search
Contact Us
Search the Studies
Browse by Institute
Searched Result
98 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number
Title
Protocol Status
Min-Max Age
Institute
Keywords
002093-N
A Single Center Prospective Natural History and Outcome Measure Validation Study of Congenital Myasthenic Syndromes
Recruitment has not started
0-99 Years
NINDS
002067-N
Cross-Sectional Evaluation of Persistence of SARS-CoV-2 Remnants After Recovery From Acute Infection
Recruitment has not started
18-110 Years
NINDS
001925-N
Functional Neuroimaging to Detect the Neural Signatures of the Unpleasantness of Pain and Effort
Recruitment has not started
18-50 Years
NINDS
001861-N
Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals with History of Stroke
Participants currently recruited/enrolled
18-99 Years
NINDS
001719-N
Ultra-Low Field (ULF) Point Of Care (POC) MRI System for Study Brain Morphology and Pathology
Participants currently recruited/enrolled
3-99 Years
NINDS
001642-N
ALLFTD: ARTFL-LEFFTDS Longitudinal Frontotemporal Lobar Degeneration
Participants currently recruited/enrolled
18-99 Years
NINDS
001608-N
Pre-operative vs. Post-operative Stereotactic Radiosurgery for Operative Metastatic Brain Tumors
Participants currently recruited/enrolled
18-99 Years
NINDS
001519-N
Central Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal Leukoencephalopathy: A Pilot Study
Participants currently recruited/enrolled
18-120 Years
NINDS
001505-N
A Phase 1/2a, Randomized, Double-Blind, Placebo-Controlled, First In-Patient Study of AJ201 to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Adults With Spinal and Bulbar Muscular Atrophy (SBMA)
Participants currently recruited/enrolled
18-120 Years
NINDS
000865-N
Natural History Protocol for Movement Disorders
Participants currently recruited/enrolled
2-100 Years
NINDS
000784-N
Assessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human Subjects
Participants currently recruited/enrolled
18-100 Years
NINDS
000711-N
Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2 (IN-PASC)
Enrolling by Invitation
18-100 Years
NINDS
000642-N
Phase II Trial of Non-Invasive Intermittent Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex in Functional Movement Disorders
Participants currently recruited/enrolled
18-80 Years
NINDS
000625-N
Investigational use of Neuromuscular Ultrasound
Participants currently recruited/enrolled
18-110 Years
NINDS
000560-N
Data Collection of Standard Care of Patients in the EMG Section
Participants currently recruited/enrolled
18-110 Years
NINDS
000428-N
An Observational Study to Assess Clinical, Molecular and Imaging Biomarkers in Spinal and Bulbar Muscular Atrophy (SBMA)
Participants currently recruited/enrolled
18-120 Years
NINDS
000196-N
Task-dependent Effects of TMS on the Neural Biomarkers of Episodic Memory
Completed Study; data analyses ongoing
18-40 Years
NINDS
000126-N
A Pilot Study of NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patients with Progressive Multifocal Leukoencephalopathy
Participants currently recruited/enrolled
18-120 Years
NINDS
000094-N
An Observational Study of Neurologic Function After COVID -19 Infection
Completed Study; data analyses ongoing
18-125 Years
NINDS
000089-N
Natural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of Health
Participants currently recruited/enrolled
18-100 Years
NINDS
000051-N
NIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)
Participants currently recruited/enrolled
48-70 Years
NINDS
21-N-0016
Phase I/II Study of Teriflunomide in HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis
Participants currently recruited/enrolled
18-120 Years
NINDS
21-N-0010
A Phase 2 Clinical Trial of Tolebrutinib, a Brain-penetrant Bruton's Tyrosine Kinase Inhibitor, for the Modulation of Chronically Inflamed White Matter Lesions in Multiple Sclerosis
No longer recruiting/follow-up only
18-120 Years
NINDS
20-N-0105
Layer-specific Contribution to Consolidation of Skill Learning in the Primary Motor Cortex
Participants currently recruited/enrolled
18-50 Years
NINDS
20-N-0077
Study of Volition: Behavioral analysis and Clinical Neurophysiological Analysis
Completed Study; data analyses ongoing
25-45 Years
NINDS
20-N-0064
An observational study to assess clinical manifestations and biomarkers in amyotrophic lateral sclerosis type 4, other inherited neurological disorders with RNA Processing Defects, and Other Neurological Diseases with a Gain of Function Mechanism.
Participants currently recruited/enrolled
5-120 Years
NINDS
20-N-0060
Mechanisms Underlying the Beneficial Effects of Naps on Motor Learning
Participants currently recruited/enrolled
18-80 Years
NINDS
20-N-0048
Corticotrophin-Releasing Hormone (CRH) Stimulation for 18F-FDG-PET Detection of Pituitary Adenoma in Cushing's Disease
Recruitment has not started
8-125 Years
NINDS
20-N-0019
The Effect of Vorinostat on ACTH Producing Pituitary Adenomas in Cushing's Disease
Participants currently recruited/enrolled
18-125 Years
NINDS
19-N-0124
Anakinra for the Treatment of Chronically Inflamed White Matter Lesions in Multiple Sclerosis
Completed Study; data analyses ongoing
18-120 Years
NINDS
19-N-0081
A Traveling Subject Study of Replicability in Conventional and Advanced MRI MS Biomarkers
Completed Study; data analyses ongoing
18-125 Years
NINDS
19-N-0036
Exploring the Relationship Between Brain Asymmetry and Attention
Completed Study; data analyses ongoing
18-35 Years
NINDS
18-N-0140
Clinical Laboratory Evaluation of Chronic Autonomic Failure
No longer recruiting/follow-up only
18-120 Years
NINDS
18-N-0133
Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery
Participants currently recruited/enrolled
18-85 Years
NINDS
18-N-0083
ASPIRO: A Phase 1/2/3, Randomized, Open-Label, Ascending-Dose, Delayed-Treatment Concurrent Control Clinical Study to Evaluate the Safety and Efficacy of AT132, an AAV8-Delivered Gene Therapy in X-Linked Myotubular Myopathy (XLMTM) Patients
No longer recruiting/follow-up only
3-5 Years
NINDS
18-N-0077
Cytokine Microdialysis For Real Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade
Completed Study; data analyses ongoing
18-125 Years
NINDS
18-N-0066
Investigating Epilepsy: Screening and Evaluation
Participants currently recruited/enrolled
8-125 Years
NINDS
18-N-0020
The Natural History of Blood-Brain Barrier Disruption in Stroke Patients with White Matter Hyperintensities (A Cohort Study)
Completed Study; data analyses ongoing
18-99 Years
NINDS
17-N-0168
Influence of Brain Oscillation-Dependent TMS on Motor Function
Participants currently recruited/enrolled
18-125 Years
NINDS
17-N-0145
PD-1 Inhibition to Determine CNS Reservoir of HIV-Infection
Completed Study; data analyses ongoing
18-120 Years
NINDS
17-N-0131
Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Participants currently recruited/enrolled
18-125 Years
NINDS
17-N-0035
Clinical and Physiological Studies of Tremor Syndromes
Completed Study; data analyses ongoing
18-125 Years
NINDS
16-N-0170
Effects of Prism Adaption and rTMS on Brain Connectivity and Visual Representation
Completed Study; data analyses ongoing
18-75 Years
NINDS
16-N-0166
Deep Brain Stimulation Surgery for Treatment of Focal Hand Dystonia
No longer recruiting/follow-up only
22-100 Years
NINDS
16-N-0114
The Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques: An Investigator-Blinded Study
Participants currently recruited/enrolled
18-120 Years
NINDS
16-N-0072
A Pilot Study of Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy with Ex Vivo Generated Polyomavirus-Specific T-cells
Completed Study; data analyses ongoing
18-125 Years
NINDS
16-N-0064
Cholinergic Receptor Imaging in Dystonia
Completed Study; data analyses ongoing
18-100 Years
NINDS
16-N-0058
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Completed Study; data analyses ongoing
18-60 Years
NINDS
16-N-0055
The Pathological Basis of MRI Signal Changes in Multiple Sclerosis: A Longitudinal In Vivo-to-Postmortem Study
Participants currently recruited/enrolled
18-120 Years
NINDS
16-N-0041
Tumor Related Epilepsy
Participants currently recruited/enrolled
8-99 Years
NINDS
16-N-0031
An All-Night Functional Magnetic Resonance Imaging Sleep Study With Auditory Stimuli
Participants currently recruited/enrolled
18-34 Years
NINDS
15-N-0177
Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy
Participants currently recruited/enrolled
18-60 Years
NINDS
15-N-0175
An Open-Label, Phase 1b Safety and Efficacy Trial of Periganglionic Resiniferatoxin for the Treatment of Intractable Pain due to Cancer-induced Bone Pain
Recruitment has not started
18-150 Years
NINDS
15-N-0167
Propensity to Develop Plasticity in the Parieto-motor Network in Dystonia from the Perspective of Abnormal High-Order Motor Processing
Completed Study; data analyses ongoing
18-65 Years
NINDS
15-N-0156
In Vivo Characterization of Inflammation with Ferumoxytol, an Ultrasmall Superparamagnetic Iron Oxide Nanoparticle, on 7 Tesla Magnetic Resonance Imaging
Completed Study; data analyses ongoing
18-70 Years
NINDS
15-N-0126
HERV-K Suppression using Antiretroviral Therapy in Volunteers with Amyotrophic Lateral Sclerosis (ALS)
Completed Study; data analyses ongoing
18-125 Years
NINDS
15-N-0125
Natural History Study of Inflammatory and Infectious Diseases of the Nervous System
Participants currently recruited/enrolled
2-110 Years
NINDS
15-N-0081
A Study of Direct Brain Recording and Stimulation for Memory Enhancement
Enrolling by Invitation
18-65 Years
NINDS
15-N-0073
A Phase I Study of Intrathecal Administration of scAAV9/JeT-GAN for the Treatment of Giant Axonal Neuropathy
Participants currently recruited/enrolled
3-99 Years
NINDS
14-N-0086
Deep Brain Stimulation Therapy in Movement Disorders
Participants currently recruited/enrolled
18-100 Years
NINDS
14-N-0083
Neural Basis of Decision Making Deficits in Traumatic Brain Injury
Completed Study; data analyses ongoing
18-60 Years
NINDS
14-N-0061
Noninvasive Pre-surgical Evaluation of Patients with Focal Epilepsy and Establishment of a Normative Imaging Database
Participants currently recruited/enrolled
8-120 Years
NINDS
13-N-0188
Natural History and Biomarkers of C9ORF72 Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Completed Study; data analyses ongoing
18-125 Years
NINDS
13-N-0165
Electrical Impedance Myography: Natural History Studies in Neuromuscular Disorders and Healthy Volunteers
Participants currently recruited/enrolled
2-110 Years
NINDS
13-N-0149
An Evaluation of HIV-associated Neurocognitive Disorders (HAND) in Virologically Controlled Patients
Participants currently recruited/enrolled
18-110 Years
NINDS
13-N-0140
Cerebrospinal Fluid Collection and Repository Storage
Participants currently recruited/enrolled
2-110 Years
NINDS
13-N-0085
Clinical Manifestations and Biorepository for Focal Dystonia
Completed Study; data analyses ongoing
18-125 Years
NINDS
13-N-0017
Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)
Participants currently recruited/enrolled
2-120 Years
NINDS
12-N-0137
A Phase 1 Open-Label Dose Escalation Safety Study of Convection Enhanced Delivery (CED) of Adeno-Associated Virus Encoding Glial Cell Line-Derived Neurotrophic Factor (AAV2-GDNF) in Subjects with Advanced Parkinson's Disease
Completed Study; data analyses ongoing
18-125 Years
NINDS
12-N-0122
Integrating Genetic and Environmental Risk Scores into an Algorithm to Predict Multiple Sclerosis Susceptibility
Completed Study; data analyses ongoing
18-125 Years
NINDS
12-N-0095
Clinical and Molecular Manifestations of Neuromuscular and Neurogenetic Disorders of Childhood
Participants currently recruited/enrolled
0-100 Years
NINDS
12-N-0083
The Effectiveness of Botulinum Toxin on Persistent Pelvic Pain in Women with Endometriosis
Completed Study; data analyses ongoing
18-50 Years
NINDS
12-N-0031
Imaging Biomarkers in Parkinson Disease
Completed Study; data analyses ongoing
18-100 Years
NINDS
11-N-0211
Deep Brain Stimulation Surgery for Movement Disorders
Participants currently recruited/enrolled
18-99 Years
NINDS
11-N-0210
NIB Repository Protocol
Completed Study; data analyses ongoing
5-125 Years
NINDS
11-N-0084
Evaluation and Diagnosis of Potential Research Subjects with Traumatic Brain Injury (TBI)
Completed Study; data analyses ongoing
18-125 Years
NINDS
11-N-0051
Surgery as a Treatment for Medically Intractable Epilepsy
Participants currently recruited/enrolled
8-99 Years
NINDS
10-N-0143
A Prospective Natural History Study of Patients with Syringomyelia
No longer recruiting/follow-up only
18-125 Years
NINDS
10-N-0122
Evaluation, Pathogenesis, and Outcome of Subjects with or Suspected Traumatic Brain Injury
Completed Study; data analyses ongoing
18-125 Years
NINDS
10-N-0012
Screening Protocol for Patients with Stroke
Participants currently recruited/enrolled
18-90 Years
NINDS
10-N-0009
Physiological Investigations of Movement Disorders
Completed Study; data analyses ongoing
18-125 Years
NINDS
09-N-0039
A Phase I Study of the Intrathecal Administration of Resiniferatoxin for Treating Severe Refractory Pain Associated with Advanced Cancer
Participants currently recruited/enrolled
18-99 Years
NINDS
09-N-0010
Biomarkers of Risk of Parkinson Disease
Completed Study; data analyses ongoing
18-70 Years
NINDS
08-N-0044
A Prospective Natural History Study of Patients with Neurofibromatosis Type 2 (NF2).
Participants currently recruited/enrolled
8-75 Years
NINDS
07-N-0190
Neurobiological Studies of Functional Movement Disorders and Non-Epileptic Seizures
Completed Study; data analyses ongoing
18-99 Years
NINDS
07-N-0122
Modulation of Motor Function by Stimulation of the Central and Peripheral Nervous System
Completed Study; data analyses ongoing
18-125 Years
NINDS
04-N-0056
The Neural Immune Mechanisms and Genetic Influences on Chronic Pelvic Pain in Women with Endometriosis
Completed Study; data analyses ongoing
18-50 Years
NINDS
03-N-0164
Evaluation and Treatment of Neurosurgical Disorders
Participants currently recruited/enrolled
4-99 Years
NINDS
01-N-0206
Phenotype/Genotype Correlations in Movement Disorders
Participants currently recruited/enrolled
2-100 Years
NINDS
01-N-0007
Evaluation, Pathogenesis, and Treatment of Patients with or at Risk for Cerebrovascular Disease (A Natural History/Disease Pathogenesis Protocol)
Participants currently recruited/enrolled
18-125 Years
NINDS
00-N-0140
A Prospective Natural History Study of VHL Patients with CNS Hemangioblastomas
No longer recruiting/follow-up only
8-75 Years
NINDS
00-N-0089
Genetic Analysis of the Chiari I Malformation
Completed Study; data analyses ongoing
1-125 Years
NINDS
00-N-0082
Characterization of Brain Morphology and Activity Using Functional and Anatomical MRI Contrast
Participants currently recruited/enrolled
18-120 Years
NINDS
00-N-0043
Clinical and Molecular Manifestations of Inherited Neurological Disorders
Participants currently recruited/enrolled
2-120 Years
NINDS
98-N-0047
Immuno-Virological Evaluation of Human T Cell Leukemia Virus Type-1 Associated Myelopathy (HAM/TSP)
Participants currently recruited/enrolled
18-120 Years
NINDS
93-N-0202
Diagnosis and Natural History Protocol for Patients with Different Neurological Conditions
Completed Study; data analyses ongoing
2-125 Years
NINDS
89-N-0045
Evaluation of Progression in Multiple Sclerosis by Magnetic Resonance Imaging (MRI)
Participants currently recruited/enrolled
18-120 Years
NINDS
85-N-0195
Botulinum Toxin for the Treatment of Neurological Disorders
Participants currently recruited/enrolled
2-100 Years
NINDS