| 002393-M | Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B) | Participants currently recruited/enrolled | 21-70 Years | NIMH | | 002277-M | PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers with Alzheimer s Disease (AD) or Mild Cognitive Impairment (MCI) | Participants currently recruited/enrolled | 50-100 Years | NIMH | | 002210-M | PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder | Participants currently recruited/enrolled | 18-70 Years | NIMH | | 002117-M | PET Imaging of Cyclooxygenase-1 in Participants with Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) | Participants currently recruited/enrolled | 18-70 Years | NIMH | | 002073-M | Characterizing the Brain Circuitry and Neural Activity Mediating Frustration | Participants currently recruited/enrolled | 18-55 Years | NIMH | | 001937-M | Phase II Efficacy Study of Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety | Participants currently recruited/enrolled | 8-17 Years | NIMH | | 001874-M | Natural History of Depression, Bipolar Disorder and Suicide Risk | Participants currently recruited/enrolled | 18-120 Years | NIMH | | 001777-M | Assessment of 11C-JMJ-129 for Imaging PDE4D in Brain and Whole Body of Healthy Volunteers | Participants currently recruited/enrolled | 18-101 Years | NIMH | | 001602-M | An Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression | Participants currently recruited/enrolled | 18-70 Years | NIMH | | 000978-M | State-Dependent Interoception, Value-Based Decision Making, and Introspection | Participants currently recruited/enrolled | 18-55 Years | NIMH | | 000776-M | An Open Trial of Transcranial Magnetic Stimulation for Youth with Treatment-Resistant Major Depressive Disorder | Clinical hold/Recruitment or enrollment suspended | 13-17 Years | NIMH | | 000754-M | NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar Disorder | Participants currently recruited/enrolled | 12-70 Years | NIMH | | 000744-M | Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Pilot Phase I and Randomized Controlled Phase II Trial | Participants currently recruited/enrolled | 8-16 Years | NIMH | | 000676-M | [18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET | Participants currently recruited/enrolled | 18-70 Years | NIMH | | 000527-M | CNS Correlates of Extended Sleep Restriction | Completed Study; data analyses ongoing | 18-39 Years | NIMH | | 000101-M | An Investigation of the Antidepressant Effects of the mGlu2/3 receptor antagonist TS-161 in Treatment-Resistant Depression | Completed Study; data analyses ongoing | 18-65 Years | NIMH | | 21-M-0031 | A Feasibility Study of Transcranial Electric Stimulation Therapy (TEST) for treatment resistant depression (TRD) | Participants currently recruited/enrolled | 25-64 Years | NIMH | | 21-M-0018 | Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array | Participants currently recruited/enrolled | 18-65 Years | NIMH | | 20-M-0166 | Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and Healthy Pediatric Populations | Participants currently recruited/enrolled | 0-8 Years | NIMH | | 20-M-0159 | Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder | Participants currently recruited/enrolled | 11-25 Years | NIMH | | 20-M-0157 | PET Imaging of Cyclooxygenase in Participants with Major Depressive Disorder (MDD) | Participants currently recruited/enrolled | 18-70 Years | NIMH | | 20-M-0082 | Phase 1 Study: PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease | Participants currently recruited/enrolled | 18-99 Years | NIMH | | 20-M-0066 | Validating the Ask Suicide-Screening Questions (ASQ) for Youth with Autism Spectrum and Neurodevelopmental Disorders | Completed Study; data analyses ongoing | 8-17 Years | NIMH | | 20-HG-0147 | An Observational Study of the Developing Brain, Impulsivity and Compulsivity | Participants currently recruited/enrolled | 6-80 Years | NIMH | | 19-M-0107 | The Mechanism of Action Underlying Ketamine's Antidepressant Effects: An Investigation of the AMPA Throughput Theory in Patients with Treatment-Resistant Major Depression | Participants currently recruited/enrolled | 18-70 Years | NIMH | | 18-M-0144 | The Effects of an ER Beta Agonist (Lilly Compound LY500307) on Estradiol-withdrawal-induced Mood Symptoms in Women with Past Perimenopausal Depression | Completed Study; data analyses ongoing | 45-65 Years | NIMH | | 18-M-0037 | Characterization and Treatment of Adolescent Depression | Participants currently recruited/enrolled | 11-25 Years | NIMH | | 18-M-0015 | Development of Non-Invasive Brain Stimulation Techniques | Participants currently recruited/enrolled | 18-65 Years | NIMH | | 17-M-0181 | Recruitment and Characterization of Healthy Research Volunteers for NIMH Intramural Studies | Participants currently recruited/enrolled | 18-70 Years | NIMH | | 17-M-0147 | Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive Episodes | Participants currently recruited/enrolled | 18-75 Years | NIMH | | 17-M-0060 | Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder | Participants currently recruited/enrolled | 18-65 Years | NIMH | | 15-M-0188 | The Neurobiology of Suicide | Participants currently recruited/enrolled | 18-70 Years | NIMH | | 15-M-0182 | Psychological Treatments for Youth with Severe Irritability | Participants currently recruited/enrolled | 8-17 Years | NIMH | | 15-M-0151 | An Investigation of the Antidepressant Effects of the Glycine Receptor Antagonist AV 101 (4-chlorokynurenine) in Major Depressive Disorder | Completed Study; data analyses ongoing | 18-65 Years | NIMH | | 15-M-0139 | Mapping the Genotype, Phenotype, and Natural History of Phelan McDermid Syndrome | Completed Study; data analyses ongoing | 1-99 Years | NIMH | | 15-M-0066 | Influence on Plasticity of Brain Temperature | Completed Study; data analyses ongoing | 18-35 Years | NIMH | | 13-M-0028 | Diagnosis of Childhood-onset Behavioral Disorders, Neuropsychiatric Disorders and Neurodevelopmental Disorders | Participants currently recruited/enrolled | 0-99 Years | NIMH | | 12-M-0128 | TMS Investigations of the Human Visual System | Participants currently recruited/enrolled | 18-50 Years | NIMH | | 11-M-0251 | A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying Puberty | Participants currently recruited/enrolled | 7-35 Years | NIMH | | 11-M-0045 | Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle | Participants currently recruited/enrolled | 18-65 Years | NIMH | | 10-M-0112 | Defining the Brain Phenotype of Children with 7q11.23 Copy Number Variation, Including Williams Syndrome and 7q11.23 Duplication Syndrome | Participants currently recruited/enrolled | 5-125 Years | NIMH | | 10-M-0047 | Top-Down Attentional Control of Visual-Processing | Participants currently recruited/enrolled | 18-100 Years | NIMH | | 10-M-0027 | Cognitive Neuroscience of Autism Spectrum Disorders | Completed Study; data analyses ongoing | 5-89 Years | NIMH | | 09-M-0176 | Functional Relevance of Dopamine Receptors in Healthy Controls and Patients with Schizophrenia: Characterization through [11C]NNC-112 and [18F]Fallypride Positron Emission Tomography | Completed Study; data analyses ongoing | 18-90 Years | NIMH | | 07-M-0021 | Development of Functional and Structural Magnetic Resonance Imaging Techniques for the Study of Mood and Anxiety Disorders | Participants currently recruited/enrolled | 18-65 Years | NIMH | | 06-M-0065 | Neurodevelopmental and Behavioral Phenotyping Screening Protocol | Participants currently recruited/enrolled | 0-125 Years | NIMH | | 05-M-0144 | MRS (Magnetic Resonance Spectroscopy) Measurement of Glutamate and GABA Metabolism in Brain | Participants currently recruited/enrolled | 18-65 Years | NIMH | | 03-M-0211 | Family Study of Affective and Anxiety Spectrum Disorders | Completed Study; data analyses ongoing | 7-120 Years | NIMH | | 03-M-0186 | The Psychobiology of Temperament: An fMRI Study | Participants currently recruited/enrolled | 0-60 Years | NIMH | | 02-M-0021 | Characterization and Pathophysiology of Severe Mood and Behavioral Dysregulation in Children and Youth | Participants currently recruited/enrolled | 7-60 Years | NIMH | | 01-M-0254 | The Evaluation of Patients with Mood and Anxiety Disorders and Healthy Volunteers | Participants currently recruited/enrolled | 3-99 Years | NIMH | | 01-M-0232 | Positron Emission Tomography (PET) Scanning in Dopamine Disorders: Parkinson's Disease and Schizophrenia | Completed Study; data analyses ongoing | 18-90 Years | NIMH | | 01-M-0192 | Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders | Participants currently recruited/enrolled | 8-65 Years | NIMH | | 00-M-0085 | Structural and Functional Imaging of Neuropsychiatric Patients and Normal Volunteers with 3.0 Tesla MRI and Magnetoencephalography (MEG) | Completed Study; data analyses ongoing | 18-120 Years | NIMH | | 95-M-0150 | A Neurobiological Investigation of Patients with Schizophrenia Spectrum Disorders and Their Siblings | Completed Study; data analyses ongoing | 18-55 Years | NIMH | | 95-M-0097 | An Endocrine Model for Postpartum Mood Disorders | Completed Study; data analyses ongoing | 18-50 Years | NIMH | | 93-M-0170 | Regional Cerebral Blood Flow Studies of Object Perception, Identification, Localization, and Memory | Participants currently recruited/enrolled | 18-65 Years | NIMH | | 92-M-0174 | The Central Nervous System Effects of Pharmacologically Induced Hypogonadotropic Hypogonadism with and without Estrogen and Progesterone Replacement | Completed Study; data analyses ongoing | 18-50 Years | NIMH | | 90-M-0088 | The Treatment of Menstrually-Related Mood Disorders with the Gonadotropin Releasing Hormone (GnRH) Agonist, Depot Leuprolide Acetate (Lupron) | Completed Study; data analyses ongoing | 18-45 Years | NIMH | | 90-M-0014 | Studies of Frontal Lobe Function During Cognitive Stimulation as Measured with Oxygen-15 Water Positron Emission Tomography in Normal Subjects and Patients with Neuropsychiatric Disorders | Completed Study; data analyses ongoing | 18-90 Years | NIMH | | 89-M-0160 | Inpatient Evaluation of Neuropsychiatric Patients | Completed Study; data analyses ongoing | 18-120 Years | NIMH | | 89-M-0006 | Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers | Participants currently recruited/enrolled | 3-120 Years | NIMH | | 88-M-0131 | The Evaluation of Women with Perimenopause-Related Mood and Behavioral Disorders | Completed Study; data analyses ongoing | 40-65 Years | NIMH | | 81-M-0126 | The Evaluation of Women with Menstrually Regulated Mood and Behavioral Disorders | Participants currently recruited/enrolled | 18-50 Years | NIMH | | 80-M-0083 | Bipolar Genetics: A Collaborative Study | Participants currently recruited/enrolled | 18-100 Years | NIMH | |