NIH Clinical Research Studies Listed By Institute of the Principal Investigator

National Eye Institute (NEI)

43 Protocols (33 Active Accrual of new subjects, 10 Follow-up of previously enrolled subjects)

Active Accrual, Protocols Recruiting New Patients 
* 17-EI-0008:
The Natural History of Geographic Atrophy Associated with Age-Related Macular Degeneration

* 16-EI-0169:
A Pilot Study to Investigate Ustekinumab (STELARA) for the Treatment of Active Sight-Threatening Uveitis

* 16-EI-0159:
A Phase I/II Trial for Intravitreous Treatment of Severe Ocular von Hippel-Lindau Disease Using a Combination of the PDGF Antagonist E10030 and the VEGF Antagonist Ranibizumab

* 16-EI-0134:
Studies of the Natural History, Pathogenesis and Outcome of Ocular Disorders

* 16-EI-0104:
Clinical and Molecular Studies in Families with Inherited Eye Disease

* 16-EI-0102:
PeriOcular and Intravitreal Corticosteroids for Uveitic Macular Edema (POINT) Trial

* 16-EI-0090:
Natural History of Spinocerebellar Ataxia Type 7 (SCA7)

* 16-EI-0046:
Uveitis/Intraocular Inflammatory Disease Biobank (iBank)

* 16-EI-0024:
Rod and Cone Mediated Function in Retinal Disease

* 15-EI-0202:
Evaluation of Oral Minocycline in the Treatment of Geographic Atrophy Associated with Age-Related Macular Degeneration

* 15-EI-0128:
The Genetics of Inherited Eye Disease

* 15-EI-0041:
Patient Expectations When Enrolling in a Phase I/II RS1 Ocular Gene Transfer Clinical Trial

* 15-EI-0038:
A Phase I/IIa Study of RS1 Ocular Gene Transfer for X-linked Retinoschisis

* 15-EI-0020:
Adaptive Optics Retinal Imaging

* 14-EI-0171:
The Focal Electro-Oculogram in Macular Disease

* 14-EI-0064:
Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions

* 13-EI-0072:
Microbiome and Ocular Inflammatory Disease

* 13-EI-0049:
Genetics of Uveal Coloboma

* 12-EI-0203:
Natural History of ABCA4-Related Retinopathies

* 12-EI-0042:
NEI Intramural Biorepository for Retinal Diseases

* 11-EI-0264:
A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Central Retinal Vein Occlusions

* 11-EI-0263:
A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Branch Retinal Vein Occlusions

* 11-EI-0245:
Generation of Induced Pluripotent Stem (iPS) Cell Lines from Somatic Cells of Participants with Eye Diseases and from Somatic Cells of Matched Controls

* 11-EI-0147:
Longitudinal Investigation of Dark Adaptation in Participants with Age-Related Macular Degeneration

* 10-EI-0140:
Genotype-Phenotype Study of Patients with Plaquenil -Induced Retinal Toxicity, with Evaluation of the ABCA4 Gene

* 10-EI-0093:
Immunogenetic Mechanisms in Behcet's Disease

* 08-EI-0102:
Screening Study for the Evaluation and Diagnosis of Potential Research Participants

* 08-EI-0099:
Epigenetics, Molecular Genetics, and Biomarkers of Degenerative and Inflammatory Ocular Diseases

* 08-EI-0043:
Age-Related Eye Disease Study (AREDS) and AREDS2 Follow-Up

* 08-EI-0031:
Visual Motor Coordination

* 06-EI-0068:
The Vitreous Proteome and Inflammatory Mediators in Ocular Inflammatory Disease

* 03-EI-0122:
Evaluation of Immune Responses to Different Antigens in Non Infectious Ocular Inflammatory Diseases

* 03-EI-0033:
X-Linked Juvenile Retinoschisis - Clinical and Molecular Studies

Active Follow-up, Protocols NOT Recruiting New Patients 

* 17-EI-0071:
AMD Ryan Initiative Study (ARIS)

* 15-EI-0052:
Pilot Phase I/II Study of the Evaluation of Interferon Gamma-1b Administered Topically for Macular Edema/Intraretinal Schisis Cysts in Rod-Cone Dystrophy (RCD) and Enhanced S-Cone Syndrome (ESCS)

* 14-EI-0108:
Pilot Study to Evaluate Oral Minocycline in the Treatment of Cystoid Macular Edema Associated with Retinitis Pigmentosa

* 14-EI-0078:
A Phase 2 Multicenter Randomized Clinical Trial of Ciliary Neurotrophic Factor (CNTF) for Macular Telangiectasia Type 2 (MacTel)

* 13-EI-0124:
A Pilot Study of Nitisinone in the Treatment of Oculocutaneous Albinism, Type 1B

* 08-EI-0169:
Evaluation and Treatment Protocol for Potential Research Participants with Ocular Diseases

* 07-EI-0213:
Laboratory of Immunology/National Eye Institute Repository

* 06-EI-0236:
National Ophthalmic Genotyping and Phenotyping Network, Stage 1 - Creation of DNA Repository for Inherited Ophthalmic Diseases

* 06-EI-0050:
Multicenter Uveitis Steroid Treatment (MUST) Trial Protocol

* 05-EI-0096:
Natural History and Genetic Studies of Usher Syndrome

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