National Institute of Dental And Craniofacial Research (NIDCR)s

National Institute of Dental And Craniofacial Research (NIDCR)

22 Protocols (16 Active Accrual of new subjects, 6 Follow-up of previously enrolled subjects)

 001833-D:

Sjogren's Team for Accelerating Medicines Partnership (STAMP)

 001521-D:

CALIBRATE: A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Encaleret Compared to Standard of Care in Participants with Autosomal Dominant Hypocalcemia Type 1 (ADH1)

 001085-D:

Phase 2 Study of the PTH-Independent Effects of Encaleret on Mineral Homeostasis in Subjects with Post-Surgical Hypoparathyroidism (PSH)

 000881-D:

A Multi-Center, Phase II, Randomized Double-Blind Trial to Evaluate the Efficacy and Safety of PhotobiomoduLatIon for the Treatment of Oral Chronic Graft-versus-Host Disease After Allogeneic Stem Cell Transplantation (The LIGHT Trial)

 000780-D:

A Phase 2 Study of Denosumab for Prevention of Skeletal Disease Progression in Children with Fibrous Dysplasia

 000350-D:

Use of Clear Aligners for The Treatment of Dental Malocclusion in Individuals with Osteogenesis Imperfecta

 20-D-0131:

Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's Syndrome; a Phase Ib-IIa Placebo-controlled Clinical Trial and Associated Mechanistic Studies

 18-D-0121:

Natural History of Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy Controls

 16-D-0040:

Natural History of Craniofacial Anomalies and Developmental Growth Variants

 15-D-0129:

Open-Label, Dose-Escalation Study Evaluating the Safety of a Single Administration of an Adeno-Associated Virus Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in Individuals with Irradiation-Induced Parotid Salivary Hypofunction.

 15-D-0051:

Characterization of Diseases with Salivary Gland Involvement

 13-D-0033:

Oral Specimen and Data Acquisition Study of Subjects Requiring Third Molar Removal

 12-D-0100:

Oral Microbial and Immunological Characterization of Patients with Immune Dysfunction

 11-D-0172:

The Pathogenesis and Natural History of Sjogren's Disease

 01-D-0184:

A Natural History Study of Bone and Mineral Disorders

 98-D-0145:

Screening and Natural History of Patients with Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome

 000798-D:

A Phase 2 Study of Burosumab for Fibroblast Growth Factor-23 Mediated Hypophosphatemia in Fibrous Dysplasia

 20-D-0122:

A Phase IIb, Open-label Dose-ranging Study Evaluating the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics, and Efficacy of CLTX-305 (encaleret) in Autosomal Dominant Hypocalcemia Type 1 (ADH1)

 20-D-0094:

Transmissibility and Viral Load of SARS-CoV-2 Through Oral Secretions

 18-D-0114:

An Open Label Pilot Study of Denosumab Treatment for Fibrous Dysplasia

 13-D-0014:

Bacterial Arrangement in Supragingival Biofilms

 07-D-0016:

Effects of PTH Replacement on Bone in Hypoparathyroidism