NIH Clinical Research Studies Listed By Protocol Number


Active Accrual, Protocols Recruiting New Patients 
* 15-I-0001:
A Phase 1 Randomized, Double-Blind, Placebo Controlled, Dose-Escalation Study to Evaluate the Safety and Immunogenicity of Prime-Boost VSV Ebola Vaccine in Healthy Adults

* 15-DK-0003:
Compassionate Use of Metreleptin in Previously-Treated Patients with Generalized Lipodystrophy

* 15-DK-0002:
Compassionate Use of Metreleptin in Previously-Treated Patients with Partial Lipodystrophy

* 14-NR-0118:
The Calibration and Validation of the PROMIS and Neuro-QOL Questionnaires in Cerebral Palsy and Congenital Muscular Dystrophy

* 14-NR-0034:
Effects of Dietary Blackcurrant Extract and PCSO-5 PernaCanaliculus Supercritical Oil) on Endothelial Function and Biomarkers of Vascular Health

* 14-NR-0023:
Development of a Proxy Motor Outcome Measure in Young Children with Neuromuscular Disease

* 14-N-0174:
Effect of Administration of Recombinant Erythropoietin on Numbers of Circulating Endothelial Progenitor Cells in Patients with Persistent Symptoms During the Subacute Period After TBI

* 14-N-0169:
Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI

* 14-N-0152:
Efficacy of Levetiracetam in Oromandibular and Cranial Dystonia: A Randomized, Double-Blind Placebo-Controlled Cross-Over Study

* 14-N-0132:
A Multicenter Observational Study to Assess the Variability of Molecular Biomarkers and Clinical Measures in Patients with Myotonic Dystrophy Type 1

* 14-N-0122:
Clinical Autonomic Disorders: A Training Protocol

* 14-N-0099:
Evaluation of Hepatic Function in Patients with Spinal and Bulbar Muscular Atrophy

* 14-N-0086:
Deep Brain Stimulation Therapy in Movement Disorders

* 14-N-0070:
Depotentiation in Focal Hand Dystonia Patients

* 14-N-0069:
Real-time fMRI Neurofeedback for Motor Rehabilitation

* 14-N-0067:
Pilot Study of the Effect of Vorinostat on Nervous System Hemangioblastomas In Von Hippel-Lindau Disease

* 14-N-0061:
Noninvasive Pre-surgical Evaluation of Patients with Focal Epilepsy

* 14-N-0051:
A Two-Part Placebo-Controlled Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of BVS857 in Patients with Spinal and Bulbar Muscular Atrophy (SBMA)

* 14-N-0033:
Phase 2 Clinical Trial of SGS-742 Therapy in Succinic Semialdehyde Dehydrogenase Deficiency

* 14-N-0030:
Pilot Trial of Botulinum Toxin and Occupational Therapy for Writer's Cramp

* 14-N-0002:
Functional Brain Imaging in Healthy Volunteers to Study Cognitive Functions

* 14-M-0193:
Investigating the Impact of Methylphenidate on Neural Response in Disruptive Behavioral Disorder

* 14-M-0164:
PET Imaging in Chronic Traumatic Encephalopathy

* 14-M-0141:
Evaluation of Specific PET Radioligand Binding To Translocator Protein

* 14-M-0117:
Assessment of [11C]ER-176 to Image Translocator Protein in Brain and Whole-Body of Healthy Subjects

* 14-M-0114:
Cognitive vs. Emotional Psycho-Pharmacological Manipulations of Fear vs. Anxiety

* 14-M-0109:
Ask Suicide-Screening Questions to Everyone in Medical Settings (asQ'em): Development of a Suicide Risk Screening Instrument for Adult Medical Inpatients

* 14-M-0085:
The Neurophysiological Effects of Intravenous Alcohol as Potential Biomarkers of Ketamine's Rapid Antidepressant Effects in Major Depressive Disorder

* 14-M-0041:
A Pathophysiological Study to Determine if Enhancing Glutamate Transporter Function Produces Antidepressant Effects in Patients with Major Depressive Disorder

* 14-M-0016:
PET Imaging of Brain mGluR1 Receptors Using [18F]FIMX

* 14-I-0206:
Novel Genetic Disorders of the Immune System

* 14-I-0199:
Human Immunity Against Staphylococcus Aureus Skin Infection

* 14-I-0194:
Screening of Volunteers for Clinical Trials of Investigational or Licensed Vaccines or Antiviral Products

* 14-I-0191:
NACC 002: A Multicenter Prospective Natural History Study of Patients Presenting with Neurocysticercosis in North America

* 14-I-0185:
A Phase III Double-Blind Randomized Crossover Study of Plerixafor Versus G-CSF in the Treatment of Patients with WHIM Syndrome.

* 14-I-0183:
VRC 207: A Phase I/1b, Open-Label, Dose-Escalation Clinical Trial to Evaluate the Safety, Tolerability and Immunogenicity of the Ebola Chimpanzee Adenovirus Vector Vaccines, VRC-EBOADC069-00-VP (cAd3-EBO) and VRC-EBOADC076-00-VP (cAd3-EBOZ), in Healthy A

* 14-I-0178:
Longitudinal Study of Immune Responses to Mycobacterium Tuberculosis (Mtb) in Subjects with Latent Tuberculosis (TB) Infection(LTBI) With or Without Concomitant Helminth Infection

* 14-I-0160:
VRC 315: A Phase I Open-Label, Randomized Study of H7 Influenza Prime-Boost Regimens in Healthy Adults: Recombinant H7 DNA Plasmid Vaccine, VRC-FLUDNA071-00-VP, Administered Alone or with Monovalent Influenza Subunit Virion H7N9 Vaccine (MIV) as Prime wi

* 14-I-0153:
An Open-Label Phase I Pilot Study to Assess the Safety/Tolerability and Efficacy of Ustekinumab for Symptomatic Gastrointestinal Inflammation Associated with Common Variable Immunodeficiency

* 14-I-0146:
The Pathogenesis and Genetics of Disseminated or Refractory Coccidiodomycosis

* 14-I-0124:
PET Imaging and Lymph Node Assessment of IRIS in Persons With AIDS

* 14-I-0121:
Longitudinal Analysis of Plasmodium Falciparum-Specific Immunity in Travelers and Immigrants from Malaria Endemic Areas to the United States

* 14-I-0115:
A Double-blind, Randomized, Placebo-controlled Study to Investigate the Efficacy and Safety of Mepolizumab in the Treatment of Eosinophilic Granulomatosis with Polyangiitis (EGPA) in Subjects Receiving Standard of Care Therapy

* 14-I-0089:
A Retrospective and Cross-Sectional Analysis of Patients Treated for Severe Combined Immunodeficiency (SCID) Since January 1, 1968

* 14-I-0081:
A Phase 2a Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Subcutaneous Benralizumab (MEDI-563) in Reducing Eosinophilia in Subjects with Hypereosinophilic Syndrome (HES)

* 14-I-0072:
A Prospective Natural History Study of Diagnosis, Treatment and Outcomes of Children with SCID Disorders

* 14-I-0063:
An Open-Label, Proof-of-Concept Study to Evaluate the Safety and Efficacy of Dexpramipexole (KNS-760704) in Subjects with Hypereosinophilic Syndrome

* 14-I-0050:
Imaging CXCR4 Expression in Subjects With Cancer Using 64 Cu-Plerixafor

* 14-I-0043:
A Phase 1, Open Label, Ascending Dose Cohort Study of the Pharmacokinetics of Anti-Influenza Hyperimmune Intravenous Immunoglobulin in Healthy Subjects

* 14-I-0039:
Elite Controller and ART-Treated HIV+ Statin Versus ASA Treatment Intervention Study

* 14-I-0035:
VRC 314: A Phase 1, Open-Label, Clinical Trial with Experimental Controlled Human Malaria Infections (CHMI) to Evaluate Safety and Durability of Protection Following Intravenous and Intramuscular Administration of PFSPZ Vaccine in Malaria-Naive Adults

* 14-I-0031:
Anti-Influenza Hyperimmune Intravenous Immunoglobulin Pilot Study(Flu-IVIG Pilot)

* 14-I-0020:
Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

* 14-I-0019:
VRC 602: A Phase 1 Dose-Escalation Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIV MAB060-00-AB (VRC01),Administered Intravenously or Subcutaneously to Healthy Adults

* 14-I-0011:
Phase I Study of Safety and Immunogenicity of Ad4-HIV Vaccine Vectors in Healthy Volunteers

* 14-I-0009:
Characterization and Management of Patients with HIV-1 Infection Who Experience Virologic Failure Despite Combination Antiretroviral Therapy

* 14-HG-0125:
Insights into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers

* 14-HG-0101:
Therapeutic Effect of Recombinant Human Growth Hormone (rhGH) on the Myopathy of Cystinosis

* 14-HG-0071:
Clinical and Basic Investigations into Known and Suspected Congenital Disorders of Glycosylation

* 14-HG-0055:
Study on Moebius Syndrome and Other Congenital Facial Weakness Disorders

* 14-HG-0048:
GENE-FORECASTSM: Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study.

* 14-H-0190:
Vascular Inflammation in Psoriasis Extension (VIP-E) Trial

* 14-H-0180:
Ultra Low Dose IL-2 Therapy as GVHD Prophylaxis in Haploidentical Allogeneic Stem Cell Transplantation

* 14-H-0172:
Assessment of Computerized Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Function in Subjects with Sickle Cell Disease

* 14-H-0147:
Multicenter Open-Label Study to Evaluate Efficacy of Gadobutrol-Enhanced Cardiac Magnetic Resonance Imaging (CMRI) for Detection of Significant Coronary Artery Disease (CAD) in Subjects with Known or Suspected CAD by a Blinded Image Analysis (GadaCAD2 at

* 14-H-0138:
Multicenter Open-Label Study to Evaluate Efficacy of Gadobutrol-Enhanced Cardiac Magnetic Resonance Imaging (CMRI) for Detection of Significant Coronary Artery Disease (CAD) in Subjects with Known or Suspected CAD by a Blinded Image Analysis

* 14-H-0127:
Characterization of the Pathogenesis of Primary and Secondary Lymphatic Disorders

* 14-H-0103:
Pilot Study to Evaluate the Effect of Fasting on the NLRP3 Inflammasome

* 14-H-0077:
Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Stem Cell Transplantation For Sickle Cell Disease and B-Thalassemia For Individuals With Higher Risk of Transplant Failure

* 14-H-0049:
Clinical Outcomes and Molecular Phenotypes in Smokers with Parenchymal Lung Disease

* 14-H-0040:
A Trial to Determine the Effect of Psoriasis Treatment on Cardiometabolic Disease

* 14-H-0026:
Individual use of Ibrutinib for a Patient with Refractory Chronic Lymphocytic Leukemia.

* 14-EI-0173:
An Investigation of Retinal Findings in Patients with Signs and Symptoms of Alzheimer's Disease Enrolled in 09-M-0198

* 14-EI-0171:
The Focal Electro-Oculogram in Macular Disease

* 14-EI-0108:
Pilot Study to Evaluate Oral Minocycline in the Treatment of Cystoid Macular Edema Associated with Retinitis Pigmentosa

* 14-EI-0078:
A Phase 2 Multicenter Randomized Clinical Trial of Ciliary Neurotrophic Factor (CNTF) for Macular Telangiectasia Type 2 (MacTel)

* 14-EI-0064:
Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions

* 14-E-0204:
A Pharmacokinetic Study to Assess the Drug Interaction Risk of the Grapefruit Juice Component and Dietary Supplement 6',7'-Dihydroxybergamottin

* 14-DK-0195:
Acute Effects of Canagliflozin, a Sodium Glucose Co-Transporter (SGLT2) Inhibitor on Bone Metabolism in Healthy Volunteers

* 14-DK-0084:
Evaluation of Safety, Tolerability, and Antiviral Activity of Chlorcyclizine HCl Alone or in Combination with Ribavirin in Patients with Chronic Hepatitis C

* 14-DK-0060:
Famine from Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes

* 14-D-0145:
Open-Label Dose Escalation Study Evaluating the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Intravenous NPSP795 in Autosomal Dominant Hypocalcemia Due to Mutations in the Calcium-Sensing Receptor Gene: A Drug Repurposing Study

* 14-CH-0177:
Fertility Preservation in Women Who will be Undergoing Gonadotoxic Therapy, Hematopoietic Stem Cell Transplantation, and in Women with Sickle Cell Disease

* 14-CH-0139:
Deep Reading as a Contemplative Practice for Women with Primary Ovarian Insufficiency: An Exporatory Pilot Study.

* 14-CH-0119:
Pilot Study of the Effects of Colchicine in Non-Diabetic Adults with Metabolic Syndrome

* 14-CH-0106:
Clinical Biomarkers in Alpha-Mannosidosis

* 14-CH-0102:
Phase 1/2 Study of Vorinostat Therapy in Niemann-Pick Disease, Type C1

* 14-CH-0028:
Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in Patients with Ectopic Cushing Syndrome

* 14-CC-0201:
A Randomized Controlled Trial to Determine the Effectiveness of a Stress Reduction Intervention in Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

* 14-CC-0179:
Losartan to Reduce Inflammation and Fibrosis Endpoints in HIV (LIFE-HIV) Trial

* 14-CC-0158:
Imaging Techniques in CT: Technical Development

* 14-CC-0143:
Sleep Disturbance and Relapse in Individuals with Alcohol Dependence: An Exploratory Mixed Methods Study

* 14-CC-0087:
Sonalleve MR-HIFU for Palliation of Bone Pain: Pilot Study

* 14-CC-0065:
Safety, Tolerability, and Efficacy of Daclatasvir and Asunaprevir, withor without BMS-791325, in Subjects Coinfected with HIV-HCV

* 14-CC-0057:
Collection of Blood From Healthy Volunteers and Clinical Research Subjects for the Production of Clinical Grade Induced Pluripotent Stem Cell (iPSC) Products

* 14-CC-0027:
The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients with Interstitial Lung Disease

* 14-C-0189:
Cognitive Testing of Tobacco Use Measurement Items for Administration with Cancer Patients and Survivors

* 14-C-0184:
Phase 1 Study of the Safety and Tolerability of ATR-101 in Adrenocortical Carcinoma

* 14-C-0176:
Phase I/II Study of Pomalidomide Combined with Modified DA-EPOCH and Rituximab in KSHV-Associated Lymphomas (Primary Effusion Lymphoma and Large Cell Lymphoma Arising in KSHV-Associated Multicentric Castleman Disease)

* 14-C-0175:
A Phase 2, Multicenter, Single-Arm Study of Moxetumomab Pasudotox in Pediatric Subjects with Relapsed or Refractory Pediatric Acute Lymphoblastic Leukemia (pALL) or Lymphoblastic Lymphoma of B-cellOrigin

* 14-C-0168:
A Phase I Clinical Trial of T-Cells Targeting B-Cell Maturation Antigen for Previously Treated Multiple Myeloma

* 14-C-0163:
Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1: Clinical, Histopathologic, and Genomic Analysis

* 14-C-0161:
Phase I Trial of the Combination of Bortezomib and Clofarabine in Adults with Refractory Solid Tumors

* 14-C-0157:
Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Dose-Adjusted-Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib,Rituximab (DA-TEDDI-R) in Primary CNS Lymphoma

* 14-C-0156:
A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in Women with BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Non-High Risk Triple Negative Breast Cancer, and High Grade Serous Ovarian Cancer at Low Genetic Risk.

* 14-C-0150:
Phase I Study of Ganetespib and Ziv-Aflibercept in Patients with Advanced Gastrointestinal Carcinomas, Non-Squamous Non-Small Cell Lung Carcinomas, Urothelial Carcinomas, and Sarcomas

* 14-C-0142:
An Open Label Phase I Study to Evaluate the Safety and Tolerability of a Modified Vaccinia Ankara (MVA) Based Vaccine Modified to Express Brachyury and T-Cell Costimulatory Molecules (MVA Brachyury-TRICOM)

* 14-C-0140:
A Pilot Study of 18F-DCFBC PET/CT in Prostate Cancer

* 14-C-0129:
Phase 1 Study of a Combination of the PARP Inhibitor, Niraparib and Temozolomide in Patients with Previously Treated, Incurable Ewing's Sarcoma

* 14-C-0128:
Collection of Pharmacokinetic Samples from Patients with Unanticipated Response or Toxicity

* 14-C-0116:
A Randomized Controlled Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in ChildrenTreated with Cranial Radiation for BrainTumors

* 14-C-0113:
Effects of an Internet Support Group for Parents of a Child with Neurofibromatosis Type 1

* 14-C-0112:
A Phase II Study of Neoadjuvant rFowlpox-PSA (L155)-TRICOM (Prostvac-F/TRICOM) in Combination with rVaccinia-PSA (L155)-TRICOM (Prostvac-V/TRICOM) in Men with Prostate Cancer Undergoing Treatment with Radical Prostatectomy

* 14-C-0110:
Phase I-II Study of the Treatment of Metastatic Cancer that Expresses MAGE-A3 Using Lymphodepleting Conditioning Followed by Infusion of Anti-MAGE-A3 HLA-A*01 Restricted TCR-Gene Engineered Lymphocytes and Aldesleukin

* 14-C-0107:
Evaluation of Ferumoxytol Enhanced MRI for the Detection of Lymph Node Metastases in Genitourinary (Prostate, Bladder and Kidney)Cancers

* 14-C-0105:
Tissue Procurement and Natural History Study of Patients with Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors

* 14-C-0104:
A Phase II Study Using Autologous Young Tumor-Infiltrating Lymphocytes (TIL) Derived from Patients with Non-Small Cell Lung Cancer Following Non-Myeloablative Lymphocyte Depleting Preparative Regimen

* 14-C-0090:
A Phase 2 Open-Label Study to Evaluate the Efficacy and Safety of VT-464 in Patients with Metastatic Castration Resistant Prostate Cancer Who Have Previously Been Treated with Enzalutamide

* 14-C-0079:
An Exploratory Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults with Metastatic, Recurrent, or Progressive Cancer

* 14-C-0062:
A Phase II Study of Cell Transfer Therapy for Metastatic Melanoma Using 41BB Selected Tumor Infiltrating Lymphocytes Plus IL-2 Following a Non-Myeloablative Lymphocyte Depleting Chemotherapy Regimen

* 14-C-0059:
A Phase I Trial of T Cells Expressing an anti-GD2 Chimeric Antigen Receptor in Children and Young Adults with Non-neuroblastoma, GD2+ Solid Tumors

* 14-C-0058:
Phase II Study of CD62L+-derived T lymphocytes transduced with a T Cell Receptor Recognizing the NY-ESO-1 Antigen and Aldesleukin Following Lymphodepletion in Patients with NY-ESO-1 Expressing Melanoma

* 14-C-0056:
Collection of Blood from Patients with Ovarian Cancer

* 14-C-0053:
Adjuvant Tumor Lysate Vaccine and Iscomatrix With or Without Metronomic Oral Cyclophosphamide and Celecoxib in Patients with Malignancies Involving Lungs, Esophagus, Pleura, or Mediastinum

* 14-C-0052:
Phase I/II Study of the Treatment of Metastatic Cancer that Expresses MAGE-A3 Using Lymphodepleting Conditioning Followed by Infusion of HLA-DP0401/0402 Restricted Anti-MAGE-A3 TCR-Gene Engineered Lymphocytes and Aldesleukin

* 14-C-0037:
A Phase 2 Study of the MET Kinase Inhibitor INC280 in Papillary Renal Cell Cancer

* 14-C-0036:
A Randomized, Prospective, Phase II Study to Determine the Efficacy of Bacillus Calmette-Guerin (BCG) Given in Combination with PANVAC[TM] Versus BCG Given Alone in Adults with High Grade Non-Muscle Invasive Bladder Cancer (NMIBC) Who Failed at Least 1 I

* 14-C-0029:
Natural History and Tissue Acquisition Study of Adrenocortical Carcinoma

* 14-C-0024:
Defibrotide for Patients with Hepatic Veno-Occlusive Disease (VOD): A Treatment IND Study

* 14-C-0022:
A Phase II Prospective Randomized Study of Cell Transfer Therapy for Metastatic Melanoma Using Tumor Infiltrating Lymphocytes Plus IL-2 Comparing Two Different Chemotherapy Preparative Regimens

* 14-C-0021:
Randomized Control Trial of Adrenalectomy versus Observation for Subclinical Hypercortisolism

* 14-C-0017:
A Randomized, Double-blind, Placebo-controlled Phase 3 Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor, PCI-32765 (Ibrutinib), in Combination with Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Subjects With Newly

* 14-C-0015:
Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA Mutations

* 14-C-0013:
A Phase I/II Trial of Ganetespib in Combination with the mTOR Inhibitor Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors

* 14-C-0005:
A Pilot Study of Metformin in Patients with a Diagnosis of Li-Fraumeni Syndrome

* 14-C-0004:
A Multicenter Phase 2 Study of the Bruton's Tyrosine Kinase Inhibitor PCI-32765 for Treatment of Relapsed Hairy Cell Leukemia

* 14-C-0001:
Phase II Study of Axitinib (AG-013736) with Evaluation of the VEGF-pathway in Metastatic, Recurrent or Primary Unresectable Pheochromocytoma/Paraganglioma

* 14-AT-0100:
Effects of Transcranial Magnetic Stimulation (TMS) on Somatosensory Perception

* 14-AT-0054:
Pain Processing and Pain Control in Experienced Yoga Practitioners

* 14-AR-0200:
Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis

* 14-AA-0192:
Brain Inflammation and Function in Alcoholism

* 14-AA-0187:
Dopamine Rhythms in Health and Addiction

* 14-AA-0181:
Unit and Clinic Evaluation, Screening, Assessment, and Management

* 14-AA-0144:
Reliability Of The Human Brain Connectome

* 14-AA-0137:
Traits Associated with Early Life Stress Among Treatment-Seeking Alcoholics

* 14-AA-0120:
Neuroimaging Omega-3 and Reward in Adults with ADHD (NORAA) Trial

* 14-AA-0094:
Neural Substrate of Approach Avoidance in Alcoholism

* 14-AA-0080:
Characterization Imaging Instruments in Alcoholics and Non-Alcoholics

* 14-AA-0066:
Behavioral and Functional MRI Task Development, Implementation, and Testing

* 14-AA-0042:
A Novel Compound for Alcoholism Treatment: A Translational Strategy

* 13-N-0198:
Acute Effects of Exercise on Memory in Healthy and Brain-Injured Individuals

* 13-N-0188:
Natural History and Biomarkers of C9ORF72 Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

* 13-N-0167:
A Longitudinal Study Assessing the Pathophysiology of Movement Disorders Utilizing the QMAT at Home Testing Device

* 13-N-0165:
Electrical Impedance Myography: Exploratory Studies in Normal Subjects and Patients with Neuromuscular Disorders

* 13-N-0163:
Investigating the Plastic Effects of Repetitive Paired Associative Stimulation (rPAS) in Dystonia

* 13-N-0149:
Screening and Recruitment for HIV-associated Neurocognitive Disorders (HAND) Studies and an Evaluation of HIV-associated Neurocognitive Disorders in Virologically Controlled Patients

* 13-N-0140:
Cerebrospinal Fluid Collection and Repository Storage

* 13-N-0135:
Pilot Study of Raltegravir, an Integrase Inhibitor, in Human T-Cell Lymphotrophic Virus-1(HTLV-1) Associated Myelopathy, Tropical Spastic Paraparesis (HAM/TSP)

* 13-N-0127:
Increasing Self-Efficacy and Outcome Expectations For Exercise in Adults with Epilepsy: An Educational Motivation Intervention - E-MOVE

* 13-N-0115:
Neural Correlates of Cognitive Impairment in Parkinson Disease

* 13-N-0104:
Natural History of Optic Neuritis

* 13-N-0088:
Open Label Extension Trial of Idebenone for Primary Progressive Multiple Sclerosis

* 13-N-0085:
Clinical Manifestations and Biorepository for Focal Dystonia

* 13-N-0076:
Gamma Frequency Transcranial Magnetic Stimulation in Dystonia

* 13-N-0047:
Treatment of Functional Movement Disorders with Psychotherapy

* 13-N-0038:
Pilot Study of Deep Brain Stimulation (DBS) for Refractory Alcoholism

* 13-N-0035:
Modulating Behavior in Humans by Entrainment with Rhythmic Transcranial Magnetic Stimulation

* 13-N-0022:
Placebo Controlled Double Blind Study of Acetyl Hexapeptide-8 in Treatment of Blepharospasm

* 13-N-0017:
Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)

* 13-N-0008:
Sildenafil for Cerebrovascular Dysfunction in Chronic Traumatic Brain Injury

* 13-M-0190:
Imaging and Genetic Investigation of Learning and Decision Making

* 13-M-0166:
Evaluation of [11C]FPEB and [11C]SP203 To Image mGluR5 Receptors In Brain

* 13-M-0164:
A Randomized Controlled Trial of Donepezil for REM Enhancement and Behavioral Change in Autism

* 13-M-0100:
Brain Inflammation In Major Depressive Disorder

* 13-M-0070:
Assessment of [11C]DPA-713 in Temporal Lobe Epilepsy

* 13-M-0028:
Diagnosis and Treatment of Childhood-onset Behavioral Disorders, Neuropsychiatric Disorders and Neurodevelopmental Disorders

* 13-M-0019:
Pilot Study to Extend the K-SADS-PL to Adolescents and Young Adults

* 13-M-0007:
Near Infra-Red Spectroscopy (NIRS) in Neurodevelopmental Disorders and Typically Developing Children

* 13-M-0004:
The Use of Daily, Intranasal Oxytocin for the Treatment of Childhood-Onset Schizophrenia (COS), a Randomized Double-Blind Trial

* 13-I-0215:
Evaluation of Anti-Hemagglutinin Antibodies as a Correlate of Protection in an H1N1 Influenza Healthy Human Challenge Model

* 13-I-0189:
VRC 601: A Phase I, Open-Label, Dose-Escalation Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC HIVMAB060-00-AB (VRC01), with Broad HIV-1 Neutralizing Activity, Administered Intravenously or Subcutaneously to HIV-Infected Adu

* 13-I-0181:
Microbiomic and Immunologic Profiling of Women with Antibiotic induced Vaginal Candidiasis

* 13-I-0177:
Natural History Study of the Complications Associated with Allogeneic Hematopoietic Stem Cell Transplantations

* 13-I-0172:
Phase I Study of the Safety of Replication-Defective Herpes Simplex Virus-2 Vaccine, HSV529, in Adults Aged 18 to 40 Years With or Without HSV Infection

* 13-I-0157:
The Natural History of GATA2 Deficiency

* 13-I-0141:
A Phase I Randomized, Double-Blind, Placebo-Controlled Study of a Multi-Antigen DNA Vaccine Prime Delivered by In Vivo Electroporation, rVSV Booster Vaccine in HIV-Infected Patients Who Began Antiretroviral Therapy During Acute/Early Infection

* 13-I-0117:
Radiofrequency Ablation (RFA) for the Treatment of Liver Abscesses in Patients with Chronic Granulomatous Disease

* 13-I-0094:
A Phase 1, Open-Label Study of Sirolimus in Eosinophil-Associated Gastrointestinal Disorders

* 13-I-0082:
Rituximab (Anti-CD20) for the Treatment of Subjects With Anticytokine Autoantibody-Associated Diseases

* 13-I-0081:
Phase 1 Study of Safety and Immunogenicity of Intranasal Ad4-H5-VTN in Ad4 Seronegative and Seropositive Volunteers

* 13-I-0077:
An Open-Label, Phase 1 Study to Assess the Safety and Tolerability of Bone Marrow Stromal Cell Infusion for the treatment of Moderate to Severe Inflammatory Bowel Disease

* 13-I-0066:
A Pilot Study to Evaluate the Safety and Efficacy of Multiple Anti-HCV Combination Therapy in Chronically Infected Hepatitis C Patients

* 13-I-0062:
A Double Blind Randomized Placebo Controlled Study Examining the Effects of a Non-Absorbable (Rifaximin) Antibiotic on the Chronic Immune Activation Observed In HIV-infected Subjects

* 13-I-0029:
A Phase 1, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of AVI-7100 in Healthy Subjects

* 13-HG-0199:
NIH Participation to USIDNET Registry

* 13-HG-0171:
Randomized Trial of Consent Interventions for NIH Whole Exome and Whole Genome Sequencing Studies

* 13-HG-0158:
Patient Perspectives and Simulated Clinical Interactions

* 13-HG-0053:
The NIH Mini Study: Metabolism, Infection and Immunity in Inborn Errors of Metabolism

* 13-H-0203:
Hydroxyurea in Pulmonary Arterial Hypertension

* 13-H-0197:
Evaluation of Serum Concentrations of Budesonide in Patients Treated for Gastrointestinal Graft-Versus-Host Disease and the Potential Interaction with Fluconazole or Voriconazole

* 13-H-0194:
Inflammatory Characterization of Known or Possible Cardiovascular Diseases

* 13-H-0183:
Cardiovascular Health and Needs Assessment in Washington D.C. - Development of a Community-Based Behavioral Weight Loss Intervention

* 13-H-0144:
Peripheral Blood Stem Cell Allotransplantation For Hematological Malignancies Using Ex Vivo CD34 Selection - a Platform For Adoptive Cellular Therapies

* 13-H-0133:
Extended Dosing with Eltrombopag in Refractory Severe Aplastic Anemia

* 13-H-0123:
An Exploratory Study to Evaluate the Effects of Roflumilast on Insulin Sensitivity and Metabolic Parameters in Prediabetic Overweight and Obese Individuals

* 13-H-0116:
A Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units (CBUs) Manufactured by the National Cord Blood Program (NCBP) and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients

* 13-H-0065:
Human Translational Studies of Inflammation and Cardiometabolic Diseases: The Psoriasis, Atherosclerosis and Cardiometabolic disease (PACI) Initiative

* 13-H-0059:
Longitudinal Observational Study of Severe Asthma

* 13-H-0051:
Bronchodilator Effects of Nebulized Versus Inhaled Albuterol In Subjects With Lymphangioleiomyomatosis

* 13-EI-0206:
A Randomized, Controlled, Double-Masked, Clinical Trial of Autologous Serum Eye Drops for Severe Ocular Chronic Graft-versus-Host Disease (GVHD) in Hematopoietic Stem Cell Transplant (HSCT) Patients

* 13-EI-0154:
Color Vision as an Outcome Measure for Clinical Trials of Inherited Retinal Degenerations

* 13-EI-0124:
A Pilot Study of Nitisinone in the Treatment of Oculocutaneous Albinism, Type 1B

* 13-EI-0102:
Gevokizumab Treatment for Active Scleritis By IL-1 Inhibition (GATSBY)

* 13-EI-0072:
Microbiome and Ocular Inflammatory Disease

* 13-EI-0049:
Genetics of Uveal Coloboma

* 13-EI-0027:
AMD Phenotype and Genotype Study (APGS)

* 13-E-0015:
Environmental Risk Factors for the Development of Myositis in Military Personnel

* 13-DK-0212:
Effect of a Eucaloric Ketogenic Diet on Energy Expenditure: A Pilot Study

* 13-DK-0200:
The Mechanism of Human Non-Shivering Thermogenesis and Basal Metabolic Rate

* 13-DK-0196:
Evaluation of Sickle Cell Liver Disease

* 13-DK-0150:
Unraveling the Mechanisms of Non-Response in Patients With and Without Cirrhosis Due to Chronic Hepatitis C

* 13-DK-0142:
The Physiology of Fatigue in Patients with Chronic Liver Disease

* 13-DK-0091:
Combination Therapy of Pegylated Interferon Alfa-2a and Tenofovir DF versus Tenofovir DF Monotherapy in HBeAg-Positive and HBeAg-Negative Chronic Hepatitis B

* 13-DK-0090:
Identifying Risk for Diabetes and Heart Disease in Women: A Study of African-American, African and White Federal Employees and Contractors

* 13-DK-0057:
Short Term Effects of Leptin Withdrawal or Initiation in Lipodystrophy Independent of Energy Intake

* 13-DK-0002:
Treatment for Non-Alcoholic Fatty Liver with Different Doses of Vitamin E

* 13-D-0033:
Diagnosis and Treatment of Patients in Need of Third Molar Removal and Oral Specimen Acquisition

* 13-D-0025:
Open-label Dose-titration Study of the Tolerability and Efficacy of Cinacalcet to Treat Fibroblast Growth Factor 23 (FGF23)-mediated Hypophosphatemia

* 13-D-0014:
Bacterial Arrangement in Supragingival Biofilms

* 13-CH-0169:
Effects of Interrupting Sedentary Behavior on Metabolic and Cognitive Outcomes in Children

* 13-CH-0139:
Blockade of Kisspeptin Signaling in Postmenopausal Women

* 13-CH-0121:
A Pilot Study Assessing the Use of Continuous Subcutaneous Hydrocortisone Infusion in the Treatment of Congenital Adrenal Hyperplasia

* 13-CH-0112:
Pilot Study to Assess Biomarkers of Changes in Barrier Function of Skeletal Muscle in Patients with a Fragile Sarcolemmal Muscular Dystrophy

* 13-CH-0097:
Fat Metabolism and Function Altering Polymorphisms in MC3R

* 13-CH-0001:
Intracerebroventricular 2-Hydroxypropyl-B-Cyclodextrin in Patients with Niemann-Pick Disease, Type C1

* 13-CC-0210:
Evaluating an Extension Assist Knee Ankle Foot Orthosis to Improve Crouch Gait in Cerebral Palsy

* 13-CC-0195:
Point Prevalence Study of Multidrug-Resistant Organism Carriage by Healthcare Personnel

* 13-CC-0180:
Studies of the Human Microbiome in Clinical Center Patients

* 13-CC-0178:
Prospective Pilot Observational Study Examining Cone Beam CT and CT Thermometry During Ablations

* 13-CC-0161:
A Description of the Oral Microbiome of Patients with Severe Aplastic Anemia

* 13-CC-0160:
The Influence of Cobicistat or Ritonavir on Dabigatran Pharmacokinetics and Pharmacodynamics in Healthy Volunteers

* 13-CC-0110:
Near-infrared Spectroscopy and Electroencephalography to Assess and Train Cortical Activation During Motor Tasks

* 13-CC-0099:
Vasti Control of Patellofemoral Kinematics in Patients with Chronic Patellofemoral Pain

* 13-CC-0092:
Prospective Randomized Multicenter Trial Comparing Navigation with 3D Roadmap vs. Conventional Angiography During Transarterial Embolization

* 13-CC-0079:
Fusion Guided Thermal Ablation Combined With External Beam Radiation for Hepatic Neoplasms

* 13-CC-0012:
A Natural History Study of Novel Biomarkers in Pulmonary Arterial Hypertension

* 13-CC-0003:
Imaging Techniques in fMRI and fMRI Reproducibility: An NIH/FDA Interagency Collaboration

* 13-C-0214:
Phase II Study of Metastatic Cancer that Expresses NY-ESO-1 Using Lymphodepleting Conditioning Followed by Infusion of Anti-NY ESO-1 Murine TCR-Gene Engineered Lymphocytes

* 13-C-0208:
Phase II Trial of Vandetanib (ZD6474, Caprelsa(R) in Children and Adults with Wild-Type Gastrointestinal Stromal Tumors

* 13-C-0202:
Tissue Procurement and Natural History Study of Patients with Malignant Mesothelioma

* 13-C-0193:
Evaluation of (68)Gallium- DOTATATE PET/CT for Detecting Primary and Metastatic Neuroendocrine Tumors

* 13-C-0176:
Tumor, Normal Tissue and Specimens from Patients Undergoing Evaluation or Surgical Resection of Solid Tumors

* 13-C-0175:
A Phase II Protocol for Subjects with Stage T1 Bladder Cancer to Evaluate Selective Bladder Preserving Treatment by Radiation Therapy Concurrent with Radio-sensitizing Chemotherapy following a Thorough Transurethral Surgical Re-Staging

* 13-C-0153:
A Phase II Trial of Enzalutamide in Combination with PSA-TRICOM in Patients with Non-Metastatic Castration Sensitive Prostate Cancer

* 13-C-0152:
A Phase I Study of Autologous Activated Natural Killer (NK) Cells +/- rhIL15 in Children and Young Adults with Refractory Solid Tumors

* 13-C-0146:
A Randomized Phase II Trial Combining Vaccine Therapy with PROSTVAC /TRICOM and Enzalutamide vs. Enzalutamide Alone in Men with Metastatic Castration Resistant Prostate Cancer

* 13-C-0145:
Pilot Study of Eovist (Gadoxetate) Enhanced MRI for the Detection of Prostate Cancer

* 13-C-0132:
Allogeneic Hematopoietic Stem Cell Transplant for Patients with Mutations in GATA2 or the MonoMAC Syndrome

* 13-C-0131:
A Pilot Study of Inpatient Hospice with Procurement of Tissue on Expiration in Thoracic Malignancies

* 13-C-0126:
Phase 2 Prospective Randomized Double Blind Trial Comparing Metastasectomy Plus Sulindac Versus Metastasectomy Alone in Patients with Stage IV Colorectal Cancer

* 13-C-0120:
A Pilot Study of Tremelimumab, A Monoclonal Antibody against CTLA-4, in combination with either Trans-Arterial Catheter Chemoembolization (TACE) or Radiofrequency Ablation (RFA) in Subjects with Hepatocellular Carcinoma (HCC)

* 13-C-0119:
Evaluation of Local Response of Prostate Cancer to Irradiation Using Multiparametric MRI and MR-Guided Biopsies

* 13-C-0118:
A Phase I Trial of TRC102 (methoxyamine HCl) in Combination with Temozolomide in Patients with Relapsed Solid Tumors and Lymphomas

* 13-C-0114:
Phase II Trial of Surgical Resection and Heated Intraperitoneal Peritoneal Chemotherapy (HIPEC) for Adrenocortical Carcinoma

* 13-C-0108:
A Phase II Study of Ponatinib in Advanced or Metastatic Medullary Thyroid Cancer

* 13-C-0105:
Molecular Profiling-based Assignment of Cancer Therapy for Patients With Advanced Solid Tumors

* 13-C-0095:
A Phase 2 Study of GI-6207 in Patients with Recurrent Medullary Thyroid Cancer

* 13-C-0093:
Phase II Study in Patients with Metastatic Ocular Melanoma Using a Non-Myeloablative Lymphocyte Depleting Regimen of Chemotherapy Followed by Infusion of Autologous Tumor-Infiltrating Lymphocytes with or without High Dose Aldesleukin

* 13-C-0083:
Efficacy of Adjuvant Mitotane Treatment in Prolonging Recurrence-Free Survival in Patients with Adrenocortical Carcinoma at Low-intermediate Risk of Recurrence

* 13-C-0080:
A Phase I Trial of Weekly Indenoisoquinoline LMP400 in Adults with Relapsed Solid Tumors and Lymphomas

* 13-C-0071:
A Phase 2 Study of Anakinra in Inflammatory Pustular Dermatoses: Evaluation of Therapeutic Efficacy and Validation of PathogenicMechanisms

* 13-C-0069:
Multi-Center, Open-Label, Randomized Study of Anti-CCR4 Monoclonal Antibody KW-0761 or Investigator's Choice in Subjects with Previously Treated Adult T-cell Leukemia-Lymphoma (ATL)

* 13-C-0064:
An Open-Label, Multicenter, Single-Arm, Phase I Dose-Escalation with Efficacy Tail Extension Study of RO5185426 in Pediatric Patients with Surgically Incurable and Unresectable Stage IIIC or Stage IV Melanoma Harboring BRAFV600 Mutations

* 13-C-0063:
A Phase I, Open-Label, Multiple-Ascending Dose Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of MSB0010718C, a Monoclonal Anti-PD-L1 Antibody, in Subjects with Metastatic or Locally Advanced Solid Tumor

* 13-C-0046:
A Phase I/II Trial of IL-13-PE in Patients with Treatment Refractory Malignancies with a Focus on Metastatic and Locally Advanced Adrenocortical Carcinoma

* 13-C-0045:
A Phase 1 Study of Recombinant Human IL15 (rhIL15) in Adults with Advanced Solid Tumors: Melanoma, Renal Cell, Non-Small Cell Lung and Head and Neck Cancer

* 13-C-0044:
A Phase 2 Study of Cabozantinib (XL184), a Dual Inhibitor of MET and VEGFR, in Patients With Metastatic Refractory Soft Tissue Sarcoma

* 13-C-0042:
A Phase I Study of XL184 (Cabozantinib, IND# 116059) in Children and Adolescents with Recurrent or Refractory Solid Tumors, Including CNS Tumors

* 13-C-0032:
A Phase I Study of Single-agent MK-1775, a Wee1 Inhibitor, in Patients with Advanced Refractory Solid Tumors

* 13-C-0016:
A Phase I Study of an Adenoviral Transduced Autologous Dendritic Cell Vaccine Expressing Human HER2/neu ECTM in Adults with Tumors with 1-3+ HER2/neu Expression

* 13-C-0009:
A Multicenter Phase I/IIB Study of NPC-1C in Combination with Gemcitabine in Patients with Metastatic or Locally Advanced Pancreatic Cancer Previously Treated with FOLFIRINOX

* 13-C-0006:
Phase II Trial Evaluating the Safety and Efficacy of Ruxolitinib in Patients with Smoldering and Chronic Adult T-cell Leukemia (ATL)

* 13-AT-0143:
Mechanisms of Pain Control in Chronic Pain Patients

* 13-AR-0086:
A Pilot Open-Label Study of Rilonacept (Arcalyst) in the Deficiency of the Interleukin-1 Receptor Antagonist (DIRA)

* 13-AR-0056:
Stopping Tumor Necrosis Factor-Alpha Inhibitors in Rheumatoid Arthritis

* 13-AR-0005:
A Phase 1b, Randomized, Double-Blind, Placebo Controlled Study with an Open Label Extension to Evaluate the Safety and Tolerability of Omalizumab, A Humanized IgG1 Monoclonal Antibody in Patients with Lupus (STOP LUPUS)

* 13-AG-0034:
Phase I, Double-Blind, Placebo-Controlled, Ascending, Single-Dose, Safety, Tolerability and Pharmacokinetic Study of Bisnorcymserine (BNC), a Highly Selective Inhibitor of Butyrylcholinesterase, in Healthy Adult Volunteers

* 13-AA-0061:
OPRM1 A118G SNP Effect on Striatal Dopamine Response to an IV Opiate

* 13-AA-0043:
Effects of Ghrelin on Alcohol Administration in Non-Treatment Seeking Heavy Drinkers

* 13-AA-0040:
A Double-Blind, Placebo-Controlled, Randomized Human Laboratory Pilot Study of Baclofen in Anxious Alcoholics

* 12-NR-0195:
Evaluation and Treatment Protocol for Potential Research Participants with Digestive Disorders

* 12-N-0182:
Positron Emission Tomography Measurement of Neuroinflammation and P-glycoprotein in Localization-Related Epilepsy

* 12-N-0137:
A Phase 1 Open-Label Dose Escalation Safety Study of Convection Enhanced Delivery (CED) of Adeno-Associated Virus Encoding Glial Cell Line-Derived Neurotrophic Factor (AAV2-GDNF) in Subjects with Advanced Parkinson's Disease

* 12-N-0122:
Integrating Genetic and Environmental Risk Scores into an Algorithm to Predict Multiple Sclerosis Susceptibility

* 12-N-0095:
Clinical and Molecular Manifestations of Neuromuscular and Neurogenetic Disorders of Childhood

* 12-N-0065:
Experienced Breacher Study: Evaluation of the Effects from Chronic Exposure to Low-Level Blast

* 12-N-0060:
Structural and Functional Brain Imaging Markers of Upper Motor Neuron Function

* 12-N-0033:
A Phase Two Clinical Trial of Buspirone Therapy in Localization-Related Epilepsy

* 12-N-0031:
Imaging Biomarkers in Parkinson Disease

* 12-N-0030:
Fatigue and Amotivation Following Mild Traumatic Brain Injury and their Influence on Service Member Community Reintegration

* 12-N-0007:
Prospective Evaluation of the Effect of Corticotropin-Releasing Hormone Stimulation on 18F-Fludeoxyglucose High-Resolution Positron-Emission Tomography in Cushing's Disease

* 12-M-0128:
TMS Investigations of the Human Visual System

* 12-M-0063:
PET Imaging of Translocator Protein in Subjects with Traumatic Brain Injury

* 12-I-0184:
Use of Fluorodeoxyglucose Positron Emission Tomography with Computed Tomography for the Evaluation of Autoimmune Lymphoproliferative Syndrome Lymphadenopathy Suggestive of Lymphoma

* 12-I-0157:
Clinical Outcomes in Persons with HIV Acquired Early in Life

* 12-I-0142:
Transcriptional Signature of HIV And TB Co-Infection

* 12-I-0133:
A Randomized, Double-Blind, Placebo Controlled Study of Liposomal Amikacin for Inhalation (Arikace ) in Patients with Recalcitrant Nontuberculous Mycobacterial Lung Disease

* 12-I-0121:
Screening of Volunteers for Clinical Trials of Investigational and Licensed Vaccines, Antiviral Products, or Live Virus Challenge Studies

* 12-I-0026:
Assessment of Glucocorticoid Responsiveness and Mechanisms of Resistance in Hypereosinophilic Syndromes

* 12-HG-0202:
The Neurobehavioral, Environmental and Genetic Factors Impacting the Clinical Course of Attention Deficit Hyperactivity Disorder

* 12-HG-0181:
The Clinical Study of Patients with Y Chromosome Variants

* 12-HG-0147:
Genetic Studies of Non-Alcoholic Fatty Liver Disease

* 12-HG-0053:
International Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of the Efficacy and Safety of KIACTA in Preventing Renal Function Decline in Patients With AA Amyloidosis

* 12-HG-0023:
The Role of the Family Genetics Health Educator in Influencing Health Promoting Behaviors

* 12-H-0158:
Quantitative Myocardial Perfusion, Myocardial Scarring and Their Contribution to Late Clinical Decompensation in Adults with Congenital Heart Disease

* 12-H-0150:
Eltrombopag Added to Standard Immunosuppression in Treatment-Naive Severe Aplastic Anemia

* 12-H-0146:
Clofarabine Followed by Lenalidomide for Treatment of High Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia

* 12-H-0141:
Prospective Evaluation of New Techniques in Radiation Reduction for Cardiovascular Computed Tomographic Angiography

* 12-H-0124:
Microvascular and Cardiac Dysfunction in Sickle Cell Disease

* 12-H-0110:
An Open-label, Non-Randomized, Single-Arm Pilot Study to Evaluate the Effectiveness of Etidronate Treatment for Arterial Calcifications due to Deficiency in CD73 (ACDC)

* 12-H-0101:
Measurement of the Reactive Hyperemia Index in Sickle Cell Patients During Pain Crisis and After Recovery

* 12-H-0090:
A Pilot Study of Cardiac Magnetic Resonance in Patients with Muscular Dystrophy

* 12-H-0084:
Metabolic Phenotyping of Subjects with Mutations Associated with Hereditary Parkinson's Disease

* 12-H-0078:
Preliminary Assessment of Direct Intra-Myocardial Injection of Autologous Bone Marrow-derived Stromal Cells on Patients Undergoing Revascularization for CAD with Depressed Left Ventricular Function

* 12-H-0069:
End-Alveolar Carbon Monoxide as a Measure of Erythrocyte Survival and Hemolytic Severity in Sickle Cell Disease

* 12-H-0064:
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients with Hematologic Malignancies and Other Indications

* 12-H-0025:
Real-time MRI Pericardiocentesis Using Passive Needles

* 12-EI-0203:
Natural History of ABCA4-Related Retinopathies

* 12-EI-0042:
NEI Intramural Biorepository for Retinal Diseases

* 12-E-0194:
Environmental Polymorphisms Registry Health and Exposures Survey

* 12-E-0190:
The Role of Functionally Relevant Cyclooxygenase-2 (COX-2) Gene Single Nucleotide Polymorphisms -765G>C and 8473T>C in Lymphocyte Differentiation

* 12-E-0089:
Bisphenol A (BPA) Pharmacokinetic (PK): Controlled Exposure Study

* 12-E-0061:
The Role of the Functionally Relevant Single Nucleotide Polymorphisms CYP2J2 -50G>T (CYP2J2 7) and EPHX2 9846A>G (EPHX2 K55R) in Human Endothelial Function

* 12-DK-0154:
Evaluation of Patients with Gastrointestinal Disease

* 12-DK-0097:
Energy Expenditure Responses to Different Temperatures

* 12-DK-0071:
Combination Entecavir and Peginterferon Therapy in HBeAG-Postive Immune-Tolerant Adults with Chronic Hepatitis B

* 12-DK-0046:
Treatment of Chronic Delta Hepatitis with Lonafarnib

* 12-DC-0152:
Normative Values in Audiovestibular Testing

* 12-D-0100:
Oral Microbial and Immunological Characterization of Patients with Immune Dysfunction

* 12-CH-0212:
Oogonial Stem Cell Isolation in Ovarian Insufficiency Patients

* 12-CH-0083:
The Effectiveness of Botulinum Toxin on Persistent Pelvic Pain in Women with Endometriosis

* 12-CH-0050:
Hormonal Regulation of Puberty and Fertility

* 12-CH-0049:
The Molecular Basis of Inherited Reproductive Disorders

* 12-CH-0016:
Bone Marrow Cell Engraftment of the Uterus

* 12-CC-0211:
A Pilot Study of the Effect of Spironolactone Therapy on Exercise Capacity and Endothelial Dysfunction in Pulmonary Arterial Hypertension

* 12-CC-0200:
Neurovascular Magnetic Resonance Imaging in the Assessment of HIV-Associated Neurocognitive Disorders

* 12-CC-0145:
Pilot Study of Yoga as Self-Care for Arthritis in Minority Communities

* 12-CC-0139:
Estimation of Brain Biomechanics using MRI

* 12-CC-0125:
Detection of Respiratory Viruses in Upper and Lower Respiratory Tract Specimens Using a Rapid Multiplex PCR

* 12-CC-0096:
Collection of Granulocytes by Apheresis of Healthy Donors Stimulated with Filgrastim (G-CSF) and Dexamethasone

* 12-C-0213:
PBTC-033 A Phase I/II Study of ABT-888, an Oral Poly (ADP-ribose) Polymerase Inhibitor, and Concurrent Radiation Therapy, Followed by ABT-888 and Temozolomide, in Children with Newly Diagnosed Diffuse Pontine Glioma (DIPG)

* 12-C-0206:
Understanding the Perceived Influence of Childhood Cancer on the Parents' Marital/Partner Relationship: A Descriptive Study

* 12-C-0205:
A Phase II Study of Cabozantinib (XL184) in Patients With Advanced/Metastatic Urothelial Carcinoma

* 12-C-0204:
A Phase I Study of Cabozantinib (XL184) plus Docetaxel and Prednisone in Metastatic Castrate Resistant Prostate Cancer

* 12-C-0197:
A Randomized Phase 2 Single-Center Study of Pomalidomide for Chronic GvHD

* 12-C-0196:
A Phase 2 Multicenter, Investigator Initiated Study of Oral Ruxolitinib Phosphate for the Treatment of Relapsed or Refractory Diffuse Large B-cell and Peripheral T-cell Non-Hodgkin Lymphoma

* 12-C-0193:
Lymphoid Malignancies and Precursors: Tissue Acquisition Protocol

* 12-C-0178:
Longitudinal Assessment and Natural History Study of Children and Young Adults with Medullary Thyroid Carcinoma

* 12-C-0175:
Prospective Procurement of Solid Tumor Tissue to Identify Novel Therapeutic Targets

* 12-C-0170:
A Phase 1B Study to Evaluate the Safety and Induction of Immune Response of CRS 207 in Combination with Pemetrexed and Cisplatin as Front-Line Therapy in Adults with Malignant Pleural Mesothelioma

* 12-C-0160:
Validation of the English Version of the Pain Interference Index and the Pain Rating Scale in Children, Adolescents, and Young Adults with Chronic Illness and their Parents

* 12-C-0159:
Effects of Treatments on the Microbiome in Healthy Volunteers and Patients with Atopic Dermatitis

* 12-C-0151:
Phase II Evaluation of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in Patients with Malignancies Involving Lungs, Esophagus, Pleura, or Mediastinum

* 12-C-0148:
SARC016: Phase 2 Study of the mTOR Inhibitor Everolimus in Combination with Bevacizumab in Patients with Sporadic and Neurofibromatosis Type 1 (NF1) Related Refractory Malignant Peripheral Nerve Sheath Tumors

* 12-C-0136:
A Phase II Randomized Trial of Lenalidomide (NSC # 703813, IND # 70116) in Pediatric Patients with Recurrent, Refractory or Progressive Juvenile Pilocytic Astrocytomas and Optic Pathway Gliomas

* 12-C-0135:
Phase I/II Trial of Mithramycin in Children and Adults with Refractory Extracranial Solid Tumors (Phase I) or Ewing Sarcoma and EWSFLI1 Fusion Transcript (Phase II)

* 12-C-0118:
A Phase II Study of Sunitinib in Patients with Advanced Relapsed or Refractory Thymoma or Thymic Carcinoma with at Least One Prior Line of Platinum-Based Systemic Chemotherapy

* 12-C-0116:
A Phase II Study of Lymphodepletion Followed by Autologous Tumor-Infiltrating Lymphocytes and High-Dose Aldesleukin for Human Papillomavirus-Associated Cancers

* 12-C-0113:
A Phase I Study of a Continuous Intravenous Infusion of Recombinant Human Interleukin IL-15 (rhIL-15) in Adults with Metastatic Cancers

* 12-C-0112:
Phase I Study of T Cells Expressing an Anti-CD19 Chimeric Receptor in Children and Young Adults with B Cell Malignancies

* 12-C-0111:
Phase I/II Study of Metastatic Cancer Using Lymphodepleting Conditioning Followed by Infusion of Anti-mesothelin Gene Engineered Lymphocytes

* 12-C-0107:
Carfilzomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma: A Clinical and Correlative Study

* 12-C-0081:
Phase I/II Study of Cediranib and Olaparib in Combination for Treatment of Recurrent Papillary-Serous Ovarian, Fallopian Tube, or Peritoneal Cancer or for Treatment of Recurrent Triple-Negative Breast Cancer

* 12-C-0080:
NaF PET/CT Repeatability, Responsiveness, and Response Assessment in Patients with Metastatic Castrate-Resistant Prostate Cancer to Bone Treated with either an Antimicrotubule Directed Agent or Androgen Receptor (AR)-Directed Therapies

* 12-C-0079:
A Phase II Multicenter Study of AMG 386 and Abiraterone in Metastatic Castration Resistant Prostate Cancer

* 12-C-0074:
Mobilization and Collection of Autologous Stem Cell for Transplantation (ASCT) for Plasma Cell Myeloma (PCM)

* 12-C-0068:
A Randomized Double-Blind Pilot Study of Topical Clobetasol 0.05% Oral Rinse for Oral Chronic Graft-Versus-Host-Disease

* 12-C-0066:
Phase I Trial of Oral 5-Fluoro-2-Deoxycytidine with Oral Tetrahydrouridine in Patients with Advanced Solid Tumors ` +

* 12-C-0058:
A Phase II Study of Everolimus (RAD001) for Children with Neurofibromatosis Type-1 and Chemotherapy-Refractory Radiographic Progressive Low-Grade Gliomas

* 12-C-0047:
A Phase I/II Study of the Safety, Pharmacokinetics and Efficacy of Pomalidomide (CC-4047) in the Treatment of Kaposi Sarcoma in Individuals With or Without HIV

* 12-C-0014:
Phase 0 Trial of [F-18]-5-Fluoro-2'-Deoxycytidine with Tetrahydrouridine

* 12-C-0009:
Phase Ib Study of the Combination of Pazopanib, an Oral VEGFR Inhibitor, and ARQ 197 (Tivantinib), an Oral MET Inhibitor, in Patients with Refractory Advanced Solid Tumors

* 12-C-0008:
An Open Label Phase I Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Maximum Tolerated Dose of the Antimesothelin Antibody Drug Conjugate BAY 94-9343 in Subjects with Advanced Solid Tumors

* 12-C-0003:
Phase I/II Trial of Yttrium-90-labeled Daclizumab (anti-CD25) Radioimmunotherapy with High-dose BEAM Chemotherapy and Autologous Hematopoietic Stem Cell Rescue in Recurrent and Refractory Hodgkin s Lymphoma

* 12-AR-8001:
Compassionate Use Treatment Protocol I4V-MC-JAGA; Treatment of Autoinflammatory Syndromes Expected to Benefit from JAK Inhibition

* 12-AG-0019:
Age-Associated Changes in Regional Adiposity and Novel Cardiovascular Risk Factors

* 12-AA-0143:
Role of Proinflammatory Signaling in Alcohol Craving

* 11-NR-0014:
Investigating Molecular-Genetic Correlates of Fatigue Experienced by Cancer Patients Receiving Treatment

* 11-N-0211:
Deep Brain Stimulation Surgery for Movement Disorders

* 11-N-0182:
The Role of the Inferior Frontal Gyrus in Long-Term Auditory Memory a rTMS Study

* 11-N-0157:
Analysis of Visual-Motor Task Electrophysiological Activity During Deep Brain Stimulation for Treatment-Resistant Movement Disorders

* 11-N-0116:
Manganese-Enhanced Magnetic Resonance Imaging in Healthy Volunteers and People with Multiple Sclerosis

* 11-N-0084:
Evaluation and Diagnosis of Potential Research Subjects with Traumatic Brain Injury (TBI)

* 11-N-0055:
The Effect of Transcranial Magnetic Stimulation on Learning with Reward in Healthy Humans

* 11-N-0051:
Surgery as a Treatment for Medically Intractable Epilepsy

* 11-N-0039:
A Phase II Clinical Trial of PRX-00023 Therapy in Localization-Related Epilepsy

* 11-M-0251:
A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying Puberty

* 11-M-0195:
The Serotonin-1A Receptor Radioligand (18F)FCWAY as a Potential Substrate for Efflux Transport at the Blood-Brain Barrier

* 11-M-0144:
Markers of Autism Spectrum Disorders in At-Risk Toddlers: A Pilot Study

* 11-M-0118:
Neuroimmune Activation in Austism: Imaging Translocator Protein Using Positron Emission Tomography (PET)

* 11-M-0104:
The Role of Oxytocin and Arginine Vasopressin in Human Placebo Analgesia

* 11-M-0045:
Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle

* 11-I-0259:
Phase 1 Study of Safety and Immunogenicity of Ad4-H5-VTN in Ad4 Seronegative and Seropositive Volunteers

* 11-I-0187:
The Natural History and Pathogenesis of Human Fungal Infections

* 11-I-0183:
Screening of Volunteers for Influenza Human Challenge Studies

* 11-I-0164:
VRC 500:Screening of Volunteers for Clinical Trials of Investigational Products and Licensed Products Evaluated for Research Purposes

* 11-I-0109:
Viral Infections in Healthy and Immunocompromised Hosts

* 11-I-0057:
Effect of Interferon Alpha 2b Intensification on HIV-1 Residual Viremia in Individuals Suppressed on Antiretroviral Therapy

* 11-I-0031:
A Randomized Double-Blind Study Comparing Oseltamivir Versus Placebo for the Treatment of Influenza in Low Risk Adults

* 11-I-0007:
Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age with X-Linked Severe Combined Immunodeficiency

* 11-HG-0218:
A Natural History Study of Patients with GNE Myopathy

* 11-HG-0207:
Clinical and Basic Investigations Into Erdheim-Chester Disease

* 11-HG-0110:
Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora Populations

* 11-HG-0093:
Personalized Genomic Research

* 11-H-0252:
Exploratory Studies of Psychophysical Pain Phenotyping and Genetic Variability in Sickle Cell Disease

* 11-H-0209:
Male Hormones for Telomere Related Diseases

* 11-H-0184:
An Extended Phase II Study of Decitabine in Subjects with High Risk Sickle Cell Disease

* 11-H-0134:
A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R Agonist), Eltrombopag, in Moderate Aplastic Anemia Patients

* 11-H-0121:
A Phase I Study of the Use of Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients with Hemolytic Disorders

* 11-H-0092:
Effects of Systemically Administered Hydrocortisone on the Human Immunome in Healthy Volunteers

* 11-H-0091:
Real-Time MRI Right Heart Catheterization Using Passive Catheters

* 11-H-0068:
Phase II Trial of Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for Treatment of Bronchiolitis Obliterans

* 11-H-0064:
Extension Study (Extended Access) of Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis Obliterans

* 11-H-0046:
Cross-Sectional Characterization of Idiopathic Bronchiectasis

* 11-EI-0264:
A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Central Retinal Vein Occlusions

* 11-EI-0263:
A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Branch Retinal Vein Occlusions

* 11-EI-0245:
Generation of Induced Pluripotent Stem (iPS) Cell Lines from Somatic Cells of Participants with Eye Diseases and from Somatic Cells of Matched Controls

* 11-EI-0173:
The Natural History of Ocular Graft-Versus Host Disease

* 11-EI-0147:
Longitudinal Investigation of Dark Adaptation in Participants with Age-Related Macular Degeneration

* 11-E-0072:
Environmental Risk Factors for the Anti-Synthetase Syndrome

* 11-E-0006:
The Role of TGF-Beta in Asthmatic Epithelial Cell Susceptibility to RSV Infection

* 11-DK-0168:
Magnetic Resonance of Body, Arterial Wall and Angiography Imaging for Non-Invasive Assessment of Arterial Distensibility, Endothelial Dysfunction and Atherosclerotic Disease Using 1.5T High Field (3T) MRI: A Technical Development Study of Cardiac and Bod

* 11-DK-0151:
Withdrawal of Therapy After Long-Term Oral Nucleos(t)ide Analogue Treatment in Patients with Chronic Hepatitis B

* 11-DK-0114:
A Pilot Trial of YF476, A Gastrin Antagonist, in Patients with Type II Gastric Carcinoids Associated with Zollinger-Ellison Syndrome

* 11-DK-0108:
Observational Study of Persons with Hepatitis B Virus Infection in North America (Cohort Study)

* 11-DK-0023:
The Nephrotic Syndrome Study Network (NEPTUNE)

* 11-D-0172:
The Pathogenesis and Natural History of Sjogren s Syndrome

* 11-D-0094:
A Randomized Within-Subject, Double-Blind, Placebo-Controlled Study of Dexamethasone Irrigation of the Parotid Glands in Primary Sj(SqrRoot)(Delta)gren's Syndrome Subjects

* 11-CH-0239:
Mood and Insulin Resistance in Adolescents At-Risk for Diabetes

* 11-CH-0208:
Effects of the Glucocorticoid Antagonist, Mifepristone, on Glucose Intolerance in Obese and Overweight Individuals

* 11-CH-0179:
Next Generation Sequencing to Identify Genetic Causes of Disease in Patients Participating in NICHD Clinical Protocols

* 11-CH-0004:
Free Fatty Acids, Body Weight, and Growth Hormone Secretion in Children

* 11-CC-0246:
Characteristics and Mechanism of Childhood-Onset Hemidystonia

* 11-CC-0152:
The Natural History of Liver Disease in a Cohort of Participants with Hepatitis B and/or Hepatitis C with or without HIV Infection

* 11-CC-0120:
Stereophotogrammetry of the Torso in Normal Individuals and Patients with Scoliosis, Chest Wall Deformations, or Obesity

* 11-CC-0083:
Beyond Intuition: Quantifying and Understanding the Signs and Symptoms of Fever

* 11-CC-0082:
Prospective Randomized Trial Comparing Navigation with Xperguide vs. Conventional Methods During Percutaneous Image Guided Procedures

* 11-C-0266:
A Phase I/II Study of the Safety and Feasibility of Administering T Cells Expressing Anti-EGFRvIII Chimeric Antigen Receptor to Patients with Malignant Gliomas Expressing EGFRvIII

* 11-C-0262:
A Randomized, Double-Blind, Phase 3 Efficacy Trial of PROSTVAC-V/F plus or minus GM-CSF in Men with Asymptomatic or Minimally Symptomatic Metastatic, Castrate-Resistant Prostate Cancer

* 11-C-0260:
A Pilot Study of the Administration of Young Tumor Infiltrating Lymphocytes Following a Non-Myeloablative Lymphocyte Depleting Chemotherapy Regimen in Metastatic Melanoma

* 11-C-0255:
Clinical, Epidemiologic, and Genetic Studies of Li-Fraumeni Syndrome

* 11-C-0247:
A Randomized Phase II Study of Tecemotide in Combination with Standard Androgen Deprivation Therapy and Radiation Therapy for untreated, intermediate and High Risk Prostate Cancer Patients

* 11-C-0242:
Collection of Blood from Patients with Cancer for Analysis of Genetic Differences in Drug Disposition

* 11-C-0233:
Pilot Study of Tocilizumab in Patients with Symptomatic Kaposi Sarcoma Herpesvirus (KSHV) - Associated Multicentric Castleman Disease

* 11-C-0225:
First In-Human Phase I Trial of NHS-IL12 in Subjects with Metastatic Solid Tumors

* 11-C-0220:
Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS) Incorporating Pilot Evaluation of KSHV Targeted Therapies

* 11-C-0200:
A Phase II Trial In Which Patients With Metastatic Alveolar Soft Part Sarcoma Are Randomized to Either Sunitinib or Cediranib Monotherapy, with Cross-Over at Disease Progression

* 11-C-0191:
Phase 1 and Phase II Study of AZD6244 for Recurrent or Refractory Pediatric Low Grade Glioma

* 11-C-0161:
A Phase 1 Study of the Mitogen Activated Protein Kinase Kinase (MEK) 1 Inhibitor AZD6244 Hydrogen Sulfate (Selumetinib Sulfate) in Children with Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)

* 11-C-0160:
A Pilot/ Phase II Study of Pentostatin Plus Cyclophosphamide Immune Depletion to Decrease Immunogenicity of SS1P in Patients with Mesothelioma

* 11-C-0149:
Evaluation of Diagnostic and Prognostic Molecular Markers in Adrenal Neoplasm

* 11-C-0148:
Epigenetically-Modified Autologous Tumor Cell Vaccs and ISCOMATRIX(TM) Adjuvant with Metronomic Oral Cyclophosphamide and Celecoxib in Pts Undergoing Resection of Sarcomas, Melanomas, Germ Cell Tumors, or Epithelial Malignancies Metastatic to Lungs, Pleu

* 11-C-0146:
A Multicenter Phase II Study of Enhancement of Immune Reconstitution and Vaccine Responses with Administration of Glyco-Recombinant Human IL-7 in Older Subjects Following Chemotherapy

* 11-C-0140:
A Phase I Study of Gemcitabine, Carboplatin and Lenalidomide (GCL) for Treatment of Patients with Advanced/Metastatic Urothelial Carcinoma (UC) and Other Solid Tumors

* 11-C-0136:
Multi-Institutional Prospective Pilot Study of Lupron to Enhance Lymphocyte Immune Reconstitution Following Allogeneic Bone Marrow Transplantation in Post-Pubertal Children and Adults with Molecular Imaging Evaluation

* 11-C-0129:
A Pilot Trial Assessing the Feasibility of Delivering Topical MTS-01 to Reduce Dermatitis in Patients Receiving Intensity Modulated Radiation with Concurrent 5-Fluorouracil and Mitomycin-C for Stage I-III Carcinoma of the Anal Canal

* 11-C-0125:
Relapsed Hematologic Malignancy After Allogeneic Hematopoietic Stem Cell Transplantation: Screening, Disease Characterization and Natural History

* 11-C-0113:
A Pilot Study of Genetically Engineered NY-ESO-1 Specific (c259) T cells in HLA-A2+ Patients with Synovial Sarcoma

* 11-C-0112:
Acquisition of Blood and Tumor Tissue Samples from Patients with Gastrointestinal Cancer

* 11-C-0102:
A Phase I/II Study of TRC105 in Combination with Sorafenib in Hepatocellular Carcinoma (HCC)

* 11-C-0096:
Pilot Trial of Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies

* 11-C-0073:
A Phase I Study of NK Cell Infusion Following Allogeneic Peripheral Blood Stem Cell Transplantation from Related or Matched Unrelated Donors in Pediatric Patients with Hematologic Malignancies

* 11-C-0061:
Phase I Trial of Z-Endoxifen in Adults with Refractory Hormone Receptor-Positive Breast Cancer, Desmoid Tumors, Gynecologic Tumors, or other Hormone Receptor-Positive Solid Tumors

* 11-C-0060:
A Phase I Pharmacokinetic Study of Belinostat for Solid Tumors and Lymphomas in Patients with Varying Degrees of Hepatic Dysfunction

* 11-C-0041:
Epigenetically-Modified Autologous Tumor Cell Vaccines with ISCOMATRIX(TM) Adjuvant and Oral Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, Thoracic Sarcomas, and Malignant Pleural Mesotheliomas

* 11-C-0034:
Dicer1-Related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study

* 11-C-0027:
A Phase I/II Trial of Crolibulin (EPC2407) plus Cisplatin in Adults with Solid Tumors with a Focus on Anaplastic Thyroid Cancer (ATC)

* 11-C-0022:
A Pharmacokinetic/Pharmacodynamic Study with a Phase I Run-In with a PARP Inhibitor (Olaparib) in Combination with Carboplatin for Refractory or Recurrent Women's Cancers

* 11-C-0016:
Multi-Center Phase I Study of Th1/Tc1 Immunotheraphy Following Autologous Hematopoietic Progenitor Cell Transplantation in High Risk Multiple Myeloma

* 11-C-0013:
Phase I/II Study of Metastatic Cancer Using Lymphodepleting Conditioning Followed by Infusion of Anti-VEGFR2 Gene Engineered CD8+ Lymphocytes

* 11-AR-0223:
Studies on the Natural History and Pathogenesis of Spondyloarthritis

* 11-AR-0156:
Bisphosphonate Users Radiographic Characteristics of the Hip (BURCH) Study

* 11-AA-0180:
Genetics of the Acute Response to Alcohol in Humans

* 11-AA-0028:
Dietary Linoleic Acid Regulation of Omega-3HUFA Metabolism: Satiety and Body Composition Among Overweight Female Subjects

* 10-N-0212:
Double Blind Combination of Rituximab by Intravenous and Intrathecal Injection Versus Placebo in Patients with Low-Inflammatory Secondary Progressive Multiple Sclerosis (RIVITaLISe)

* 10-N-0199:
Ethanol Response in Essential Tremor: Clinical and Neurophysiological Correlates

* 10-N-0185:
Neural Dynamics and Connectivity in Response Inhibition and Traumatic Brain Injury

* 10-N-0143:
A Prospective Natural History Study of Patients with Syringomyelia

* 10-N-0125:
Investigating Mechanism of Action of DAC HYP in the Treatment of High-Inflammatory Multiple Sclerosis (MS)

* 10-N-0092:
Genetics of Motor Learning

* 10-N-0012:
Screening Protocol for Patients with Stroke

* 10-N-0009:
Physiological Investigations of Movement Disorders

* 10-N-0003:
Recording and Modulation of Neuronal Mechanisms During Operant Conditioning: A MEG Study

* 10-M-0112:
Defining the Brain Phenotype of Children with Williams Syndrome

* 10-M-0047:
Top-Down Attentional Control of Visual-Processing

* 10-M-0027:
Cognitive Neuroscience of Autism Spectrum Disorders

* 10-I-0216:
Studies of Disorders with Increased Susceptibility to Fungal Infections

* 10-I-0210:
A Randomized Double-Blind Phase 2 Study Comparing the Efficacy, Safety, and Tolerability of Combination Antivirals (Amantadine, Ribavirin, Oseltamivir versus Oseltamivir for the Treatment of Influenza in Adults at Risk for Complications

* 10-I-0205:
Assessment of Alterations in Immune Function During Pregnancy and Post Parturition

* 10-I-0197:
Admission and Management of Occupational or Other Exposures to Biodefense/Bioterrorism Agents or to Epidemic/Emerging Infectious Diseases

* 10-I-0196:
Immunopathogenesis of Food Allergy and Eosinophilic Gastrointestinal Disorders

* 10-I-0195:
Training Protocol on the Natural History of Tuberculosis

* 10-I-0148:
Natural History of Atopic Dermatitis and Other Genetic/Congenital Diseases Associated with Allergic Inflammation

* 10-I-0139:
Searching for Persistence of Infection in Lyme Disease

* 10-I-0123:
Assessment of the Biochemical Response to Interferon-Gamma in Subjects with Specific Gene Mutation in Chronic Granulomatous Disease

* 10-I-0109:
VRC 900: Evaluation of Tissue-Specific Immune Responses in Adults 18 Years of Age and Older

* 10-I-0101:
A Randomized, Placebo-controlled, Double-Blind Pilot Study of Single-Dose Humanized Anti-IL5 Antibody (Reslizumab) for the Reduction of Eosinophilia Following Diethylcarbamazine Treatment of Loa Loa Infection

* 10-I-0095:
Collection of Peripheral Blood Stem Cells Using G-CSF and Plerixafor in Normal Volunteers

* 10-I-0043:
A Randomized, Open-Label, Phase 2, Multicenter Safety and Exploratory Efficacy Study of Investigational anti-Influenza Immune Plasma for the Treatment of Influenza

* 10-I-0029:
Non-Invasive Assessment of Atherosclerosis in Patients with CGD and Other Disorders of the Immune System

* 10-I-0014:
The Natural History of Severe Viral Infections and Characterization of Immune Defects

* 10-HG-0065:
Whole Genome Medical Sequencing for Gene Discovery

* 10-H-0168:
Submission of Autologous and Related Allogeneic Hematopoietic Stem Cell Transplant Data to the Center for International Blood and Marrow Transplant Research (CIBMTR) and the National Marrow Donor Program (NMDP)

* 10-H-0165:
Effects of Rosuvastatin on the Immune System in Healthy Volunteers with Normal Cholesterol

* 10-H-0162:
Collection of Blood, Bone Marrow, Leukapheresis, and Tissue Biopsy Samples from Patients and their Family Members for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Laboratory Research Studies

* 10-H-0154:
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused with a Reduced Dose of Non-Mobilized Donor T-Cells

* 10-H-0141:
A Phase II Study of Ofatumumab-Based Induction Chemoimmunotheraphy Followed by Consolidation Ofatumumab Immunotherapy in Previously Untreated Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

* 10-H-0126:
Cardiovascular Disease Discovery Protocol

* 10-H-0097:
A Study of the Kinetics of Lymphoid Cells in Patients with Monoclonal B-Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL), Mantle Cell Lymphoma (MCL) and Healthy Volunteers.

* 10-H-0088:
Evaluation of Oral Alpha-Cyclodextrin for Decreasing Serum Cholesterol

* 10-H-0039:
New Techniques to Evaluate Mitral Regurgitation

* 10-EI-0140:
Genotype-Phenotype Study of Patients with Plaquenil -Induced Retinal Toxicity, with Evaluation of the ABCA4 Gene

* 10-EI-0093:
Immunogenetic Mechanisms in Behcet's Disease

* 10-EI-0016:
Internal Monitoring of Eye Movement in Schizophrenia

* 10-E-0134:
Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage

* 10-E-0130:
The Role of Glucocorticoid Receptor SNPs in Receptor Function and Metabolic Disease

* 10-E-0129:
Study of the Effect of Innate Immunity on the Inflammatory Response to Endotoxin

* 10-E-0063:
Sample Collection Registry for Quality Control of Biological and Environmental Specimens and Assay Development and Testing

* 10-DK-0163:
Metabolic Effects of Non-Nutritive Sweeteners

* 10-DK-0135:
Role of Donor Genetics and Recipient Genetics in Kidney Transplant Outcomes

* 10-D-0180:
A Pilot Trial Targeting mTOR as a Novel Mechanism-Based Neoadjuvant Therapy for Head and Neck Cancer

* 10-CH-0198:
Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain Imaging

* 10-CH-0083:
A Phase I Trial of Safety and Immunogenicity of Gardasil Vaccination Post Stem Cell Transplantation in Patients with and without Immunosuppression

* 10-CC-0217:
A Comparison of Methods for Assisting Needle Angle Selection During Image-Guided Tissue Biopsy

* 10-CC-0214:
Randomized Trial of Imaging Versus Risk Factor Based Therapy for Plaque Regression

* 10-CC-0200:
Multiplex Microarray Chip-Based Diagnosis of Respiratory Infections

* 10-CC-0153:
Noninvasive Imaging of Heart Failure

* 10-CC-0149:
Comparing Expectorated and Induced Sputum and Pharyngeal Swabs for Cultures, AFB Smears, and Cytokines in Pulmonary Nontuberculous Mycobacterial Infection

* 10-CC-0118:
Long Term Clinical Correlates of TBI: Imaging, Biomarkers, and Clinical Phenotyping Parameters

* 10-CC-0115:
Imaging Techniques in MRI

* 10-CC-0073:
Physical, Functional and Neurological Effects of Two Lower Extremity Exercise Programs in Children with Cerebral Palsy

* 10-CC-0053:
Collection of Bone Marrow from Healthy Volunteers and Patients for the Production of Clinical Bone Marrow Stromal Cell (BMSC) Products

* 10-C-0219:
A Phase I Trial of Lenalidomide and Radiotherapy in Children with Diffuse Intrinsic Pontine Gliomas and High-grade Gliomas

* 10-C-0201:
Apheresis and CD34+ Selection of Mobilized Peripheral Blood CD34+ Cells from Patients with DOCK8 Deficiency, LAD-1, and GATA2 Deficiency

* 10-C-0174:
Related and Unrelated Donor Hematopoietic Stem Cell Transplant of DOCK8 Deficiency

* 10-C-0166:
A Phase II Study Using Short-Term Cultured, Autologous Tumor-Infiltrating Lymphocytes Following a Lymphocyte Depleting Regimen in Metastatic Cancers

* 10-C-0138:
Allogeneic Tumor Cell Vaccine with Metronomic Oral Cyclophosphamide and Celecoxib as Adjuvant Therapy for Lung and Esophageal Cancers, Thymic Neoplasms, Thoracic Sarcomas, and Malignant Pleural Mesotheliomas

* 10-C-0111:
Protocol for the Enrollment on the Official COG Registry, The Childhood Cancer Research Network (CCRN) Children s Oncology Group

* 10-C-0102:
Clinical and Genetic Studies in Familial Non-Medullary Thyroid Cancer

* 10-C-0086:
Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological Studies

* 10-C-0056:
A Phase I Study of Indenoisoquinolines LMP400 and LMP776 in Adults With Relapsed Solid Tumors and Lymphomas

* 10-C-0054:
Administration of Anti-CD19-Chimeric-Antigen-Receptor-Transduced T-cells from the Original Transplant Donor to Patients with Recurrent or Persistent B-Cell Malignancies After Allogeneic Stem Cell Transplantation

* 10-C-0052:
Phase II Study of Dose-Adjusted EPOCH+/-Rituximab in Adults with Untreated Burkitt Lymphoma, c-MYC Positive Diffuse Large B-Cell Lymphoma and Plasmablastic Lymphoma

* 10-C-0041:
A Phase II Trial of Valproic Acid in Patients with Advanced Thyroid Cancers of Follicular Origin

* 10-C-0011:
Phase II Trial of Alemtuzumab (Campath) and Dose-Adjusted EPOCH-Rituximab (DA-EPOCH-R) in Relapsed or Refractory Diffuse Large B-Cell and Hodgkin Lymphomas

* 10-AG-0423:
A Pilot Study of Exendin-4 in Alzheimer s Disease

* 10-AA-0046:
Effects of Corticotropin-Releasing Hormone Receptor 1 (CRH1) Antagonism on Stress-Induced Craving in Alcoholic Women with High Anxiety: an Experimental Medicine Study

* 09-NR-0131:
Fatigue in Healthy Individuals

* 09-NR-0088:
Molecular-Genetic Correlates of Fatigue in Cancer Patients Receiving Localized External Beam Radiation Therapy

* 09-NR-0064:
Brain-Gut Interactions in Overweight and Normal Weight Patients with Chronic Abdominal Pain

* 09-N-0197:
Double Blind Placebo-Controlled Phase I/II Clinical Trial of Idebenone in Patients with Primary Progressive Multiple Sclerosis

* 09-N-0118:
Investigation of Neurofeedback with Real-Time fMRI in Healthy Volunteers and Patients with Hyperkinetic Movement Disorders

* 09-N-0117:
An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients with Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-Grade Glioma

* 09-N-0039:
A Phase I Study of the Intrathecal Administration of Resiniferatoxin for Treating Severe Refractory Pain Associated with Advanced Cancer

* 09-N-0032:
Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the CNS

* 09-N-0010:
Biomarkers of Risk of Parkinson Disease

* 09-M-0198:
Screening and Evaluation of Patients with Signs and Symptoms of Alzheimer's Disease

* 09-M-0194:
Characterizing Lone Parenting: A Multi-Institutional Pilot Study of the Perceptions of Support and Perceived Stress of Lone Parents of Children with Cancer

* 09-M-0176:
Functional Relevance of Dopamine Receptors in Healthy Controls and Patients with Schizophrenia: Characterization through [11C]NNC-112 and [18F]Fallypride Positron Emission Tomography

* 09-M-0123:
Regional Rates of Cerebral Protein Synthesis: Effects of Sleep and Memory Consolidation

* 09-M-0034:
A Controlled Trial of Citalopram Added to Methylphenidate in Youth with Severe Mood Dysregulation

* 09-M-0022:
The Use of a Distress Thermometer in a Pediatric Research Setting: An Exploratory, Pilot Study

* 09-I-0246:
A Phase II, Open Label Trial of a Vaccine (FSME-IMMUN 0.5 mL Baxter) Against Tick-Borne Encephalitis (TBE) for NIAID Workers Manipulating Tick-Borne Encephalitis Virus (TBEV) in the Laboratory

* 09-I-0232:
An International Observational Study to Characterize Adults Who Are Hospitalized with Complications of Influenza

* 09-I-0200:
A Phase I Study of Mozobil (TM) in the Treatment of Patients with WHIMS

* 09-I-0184:
Studies in the Pathogenesis of Systemic Capillary Leak Syndrome

* 09-I-0172:
Natural History of Bronchiectasis

* 09-I-0133:
Establishing Fibroblast-derived Cell Lines from Skin Biopsies of Patients with Immunodeficiency or Immunodysregulation Disorders

* 09-I-0129:
A Randomized Double-Blinded, Placebo-Controlled Study of Omalizumab for Idiopathic Anaphylaxis

* 09-I-0126:
Pathogenesis of Physical Induced Urticarial Syndromes

* 09-I-0102:
Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ Lymphocytopenia

* 09-I-0086:
Screening Protocol for Genetic Diseases of Allergic Inflammation and Mast Cell Homeostasis and Activation

* 09-I-0049:
Normal Blood, Bone Marrow and Buccal Mucosa Protocol

* 09-I-0030:
Clinical and Immunologic Monitoring of Patients with Known or Suspected HIV Infection

* 09-I-0013:
Biomarkers of Inflammation, Coagulation, and Endothelial Function in HIV-Infected Adults

* 09-HG-0128:
Leukodystrophies of Unknown Cause

* 09-HG-0035:
Clinical, Cellular, and Molecular Investigations into Oculocutaneous Albinism

* 09-H-0244:
A Randomized, Placebo-Controlled, Double-Blind Pilot Study of Pioglitazone Hydrochloride in Severe, Refractory Asthma

* 09-H-0229:
Collection of Blood, Bone Marrow, Skin Biopsies and Buccal Mucosa Samples from Healthy Volunteers for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Protocols Laboratory Research Studies

* 09-H-0225:
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease and Beta-Thalassemia

* 09-H-0201:
Screening Protocol for Subjects being Evaluated for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Protocols

* 09-H-0199:
A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R agonist), Eltrombopag, in Patients with Low to Int-2 Risk Myelodysplastic Syndrome (MDS)

* 09-DK-0223:
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

* 09-DK-0140:
Natural History of Autoimmune Diabetes and Its Complications

* 09-DK-0097:
Vitamin E Pharmacokinetics and Biomarkers in Women

* 09-CH-0059:
Molecular Bases of Response to Copper Treatment in Menkes Disease, Related Phenotypes, and Unexplained Copper Deficiency

* 09-C-0242:
Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms

* 09-C-0214:
A Multi-Histology Phase II Study of 5-Fluoro-2'-Deoxycytidine with Tetrahydrouridine (FdCyd + THU)

* 09-C-0192:
Phase II Study of Cediranib (AZD2171) in Patients With Alveolar Soft Part Sarcoma

* 09-C-0173:
A Phase I Study of Belinostat in Combination with Cisplatin and Etoposide in Adults with a Focus on Small Cell Lung Cancer and other Cancers of Neuroendocrine Origin

* 09-C-0161:
Follow Up Protocol for Subjects Previously Enrolled in NCI Surgery Branch Studies

* 09-C-0130:
Pilot Study of Liposomal Doxorubicin Combined with Bevacizumab Followed by Bevacizumab Monotherapy in Adults with Advanced Kaposi s Sarcoma

* 09-C-0120:
An Exploratory Evaluation of Biomarkers in Blister Fluid in Healthy Volunteers and Irradiated Skin

* 09-C-0111:
A Phase 1, Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Intravenous Dimethane Sulfonate (DMS612, NSC 281612) in Advanced Malignancies

* 09-C-0100:
A Natural History Study of Patients Receiving High Dose Rate Brachytherapy

* 09-C-0082:
Assessment of the Safety and Feasibility of Administering T cells Expressing an anti-CD19 Chimeric Antigen Receptor to Patients with B-cell Lymphoma or Leukemia

* 09-C-0079:
The Natural History of Solid Organ Cancer Stem Cells (SOCSC)

* 09-C-0057:
A Phase II Multi-Center Study of Bevacizumab in Combination with Ixabepilone in Subjects with Advanced Renal Cell Carcinoma

* 09-C-0053:
Autologous and Related Allogeneic Hematopoietic Stem Cell Transplant and Cellular Therapies Data Submission to the Center for International Blood and Marrow Transplant Research (CIBMTR) and the National Marrow Donor Program (NMDP)

* 09-C-0019:
A Phase I Study of Dasatinib in Combination with Bevacizumab in Advanced Solid Tumors

* 08-NR-0132:
Evaluation and Diagnosis of Potential Research Subjects with Pain and Fatigue Syndromes

* 08-N-0215:
Understanding the Anatomy and Physiology of the Sensory Experience and its Role in Generating Tics in Tourette Syndrome

* 08-N-0181:
Role of Neurotransmission and Functional CNS Networks in Spasmodic Dysphonia and Other Focal Dystonias

* 08-M-0211:
Safety of Transcranial Direct Current Brain Stimulation (TDCS) for Improvement of Psychotic Symptoms and Cognitive Functioning in Childhood Onset Schizophrenia (COS)

* 08-M-0150:
An Investigation to Determine Whether Levels of P11 Protein in Peripheral Blood Cells Correlate with Treatment Response to Citalopram in Patients with Major Depressive Disorder

* 08-M-0066:
PET Evaluation of Brain Peripheral Benzodiazepine Receptors using [11C]PBR28 in Neurological Disorders

* 08-M-0052:
fMRI Investigation of Cortical Reorganization and Phantom Limb Pain Following Amputation

* 08-I-0221:
Analysis of HIV-1 Replication During Antiretroviral Therapy

* 08-I-0184:
Studies in the Pathogenesis of Idiopathic Anaphylaxis

* 08-HG-0224:
Clinical and Genetic Studies of VACTERL Association

* 08-HG-0059:
Studies of Skin Microflora in Healthy Individuals and Atopic Dermatitis Patients

* 08-H-0186:
Safety and the Anti-Tumor Effects of Escalating Doses of Adoptively Infused Ex Vivo Expanded Autologous Natural Killer (NK) Cells Against Metastatic Cancers or Hematological Malignancies Sensitized to NK TRAIL Cytotoxicity with Bortezomib

* 08-H-0185:
Technical Development of Interventional Cardiovascular Magnetic Resonance Imaging in Normal Volunteers

* 08-H-0156:
Screening of Subjects to Determine Eligibility to Safely Participate in Blood Disorders Studies

* 08-H-0105:
Natural History Study of Monoclonal B Cell Lymphocytosis (MBL) and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

* 08-H-0046:
Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive Therapy

* 08-EI-0169:
Evaluation and Treatment Protocol for Potential Research Participants with Ocular Diseases

* 08-EI-0102:
Screening Study for the Evaluation and Diagnosis of Potential Research Participants

* 08-EI-0099:
Epigenetics, Molecular Genetics, and Biomarkers of Degenerative and Inflammatory Ocular Diseases

* 08-EI-0043:
Age-Related Eye Disease Study (AREDS) and AREDS2 Follow-Up

* 08-EI-0031:
Visual Motor Coordination

* 08-DK-0173:
A Trial of Segmental Stiffening Wires to Improve the Efficiency and Patient Tolerability of Colonoscopy

* 08-DK-0138:
A New Method for Determining Gastric Acid Output Using a Wireless Capsule

* 08-DK-0098:
Natural History of Familial Carcinoid Tumor

* 08-DK-0004:
High Throughput Screening of Compound Libraries to Discover a Drug for the Treatment of Sickle Cell Disease

* 08-CH-0213:
WAGR Syndrome and Other 11p Contiguous Gene Deletions: Clinical Characterization and Correlation with Genotype

* 08-CH-0170:
Establishment of a Fibroid Tissue Bank

* 08-CC-0205:
Evaluation of Assessments of Motor Performance, Physical Impairments and Functional Abilities

* 08-CC-0133:
The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients with Pulmonary Hypertension: Initial Studies for Establishing Guidelines

* 08-CC-0024:
Immunologic and Virologic Response in HIV Infected Progressors after Infusion of Lymphocytes from HIV Infected "Elite" Long-Term Non-Progressors

* 08-C-0214:
A Pilot Study to Evaluate Neuropsychological Outcome Measures and their Relationship with Prognosis in Patients Receiving Radiation Therapy for Brain Metastases

* 08-C-0200:
A Pilot Study of 18F Fluorothymidine (FLT) PET/CT in Lymphoma

* 08-C-0130:
A Phase II Trial of Peginterferon Alpha-2b (PEG-Intron) for Neurofibromatosis Type 1 Related Unresectable, Symptomatic or Life-Threatening Plexiform Neurofibromas

* 08-C-0088:
Low Intensity Allogeneic Hematopoietic Stem Cell Transplantation Therapy of Metastatic Renal Cell Carcinoma using Early and Multiple Donor Lymphocyte Infusions Consisting of Sirolimus-Generated Donor Th2 Cells

* 08-C-0079:
Natural History Study and Longitudinal Assessment of Children, Adolescents, and Adults with Neurofibromatosis Type 1

* 08-AG-0238:
Development of 3T Magnetic Resonance Research Methods for NIA Studies

* 08-AA-0178:
Computer-Assisted Self-Administration of Ethanol (CASE) in Humans

* 07-N-0190:
Neurobiological Studies of Psychogenic Movement Disorders and Non-Epileptic Seizures

* 07-N-0122:
Modulation of Motor Function by Stimulation of the Central and Peripheral Nervous System

* 07-N-0103:
Imaging Serotoninergic Neurotransmission in Epilepsy

* 07-M-0082:
PET Imaging of Brain mGluR5 Receptors Using [18F]SP203 and [11C]SP203

* 07-M-0035:
PET Whole Body Imaging Using a Peripheral Benzodiazepine Receptor Ligand [C-11]PBR28

* 07-M-0021:
Development of Functional and Structural Magnetic Resonance Imaging Techniques for the Study of Mood and Anxiety Disorders

* 07-I-0229:
Influenza in the Non-immunocompromised and Immunocompromised Host

* 07-I-0183:
The Collection of Research Samples and/or Data for Repository from Related or Unrelated Hematopoietic Stem Cell Transplantation Recipients for the National Marrow Donor Program

* 07-I-0142:
Research Respiratory Tract Procedures

* 07-I-0075:
Allogeneic and Matched Unrelated Donor Stem Cell Transplantation for Congenital Immunodeficiencies or Patients with Autoinflammatory/Immunodysregulatory Conditions: Busulfan-Based Conditioning with Campath- 1H or h-ATG, Radiation, and Sirolimus

* 07-I-0033:
Screening Protocol for Detection and Characterization of Infections and Infection Susceptibility

* 07-HG-0076:
A Phase One Treatment Trial of the Circadian Sleep Disturbance in Smith-Magenis Syndrome (SMS)

* 07-HG-0002:
ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot Study

* 07-H-0157:
Suburban/NHLBI Cardiovascular Disease Screening Protocol

* 07-H-0113:
Collection of Blood, Bone Marrow, and Buccal Mucosa Samples from Healthy Volunteers

* 07-H-0030:
Metabolic Regulation by Tumor Suppressor p53 in Li-Fraumeni Syndrome

* 07-H-0005:
Pilot Study of Topical Dexamethasone 0.01% Solution for Prevention of Oral Chronic Graft Versus Host Disease

* 07-EI-0145:
Ocular Impact of X Chromosome Karyotype and Sex Hormones in Turner Syndrome

* 07-E-0023:
Innate Immunity Signal Transduction in Human Leukocytes

* 07-DK-0212:
Prospective Evaluation of Albuminuria in HIV Positive Patients

* 07-DK-0207:
Tenofovir Disoproxil Fumarate Alone Versus its Combination with Emtricitabine for Treatment of Chronic Hepatitis B

* 07-DK-0202:
Thyroid Hormones Homeostasis and Energy Metabolism Changes During Exposure to Cold Temperature in Humans

* 07-DK-0115:
Natural History of Type 2 Diabetes Mellitus in Children and Young Adults

* 07-DK-0077:
Study of the Phenotype of Overweight and Obese Adults

* 07-D-0016:
Effects of PTH Replacement on Bone in Hypoparathyroidism

* 07-CH-0192:
Detection and Treatment of Endocrine Abnormalities in Childhood Cancer Survivors and Hematopoitic Stem Cell Transplant Recipients

* 07-C-0195:
Phase II Trial of Targeted Immune-Depleting Chemotherapy and Reduced-Intensity Allogeneic Hematopoietic Stem Cell Transplantation Using 8/8 and 7/8 HLA-matched Unrelated Donors and Utilizing Two Graft-versus-Host Disease Prophylaxis Regimens for the Trea

* 07-C-0110:
Analysis of Stored Data Collected from Individuals Administered Neurobehavioral Assessments on IRB-Approved Protocols

* 07-C-0100:
Collection of Blood from Patients with Prostate Cancer

* 07-C-0086:
Pilot Study of Educational Interventions in Pediatric Hematopoietic Stem Cell Donors to Increase Knowledge of Donation and Transplantation Procedures

* 06-NR-0229:
Neurotropin Treatment of Fibromyalgia

* 06-N-0047:
Reference Values for Plasma Catechols

* 06-M-0215:
Antidepressant Effects on cAMP Specific Phosphodiesterase (PDE 4) in Depressed Patients

* 06-M-0214:
PET Measurement of Regional Rates of Cerebral Protein Synthesis in Subjects with Fragile X Syndrome

* 06-M-0065:
Screening Protocol for Studies of the Pediatrics and Developmental Neuroscience Branch

* 06-I-0153:
A Pilot Study of Hepatic Fibrosis in HIV/AIDS Patients with Chronically Elevated Transaminases on Antiretroviral Therapy

* 06-I-0015:
Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death

* 06-HG-0055:
Functional Imaging in Subjects with Glucocerebrosidase Mutations

* 06-H-0222:
Role of Helicobacter Pylori and Its Toxins in Pulmonary and Oropharyngeal Disease

* 06-H-0190:
Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders with Alemtuzumab (Campath)

* 06-H-0072:
Atorvastatin as a Disease Modifying Agent in Stage II and III Pulmonary Sarcoidosis: A Randomized, Double-Blind, Placebo-Controlled Trial

* 06-EI-0236:
National Ophthalmic Genotyping and Phenotyping Network, Stage 1 - Creation of DNA Repository for Inherited Ophthalmic Diseases

* 06-EI-0068:
The Vitreous Proteome and Inflammatory Mediators in Ocular Inflammatory Disease

* 06-EI-0059:
Clinical and Molecular Studies in Families with Glaucoma and Related Diseases

* 06-EI-0058:
Clinical and Molecular Studies in Families with Myopia and Related Diseases

* 06-DK-0142:
Peripheral Blood Collection of Adult Stem Cells

* 06-CH-0186:
Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type C

* 06-CH-0039:
Pilot Program for Targeted Prevention of Child or Adolescent Weight Gain

* 06-CH-0011:
Natural History Study of Patients with Excess Androgen

* 06-CH-0010:
Remodeling of Chromatin-Based Epigenetic Structures in Development and Aging

* 06-C-0219:
An Exploratory Study of Biologic and Pathophysiologic Effects of Radiation Therapy in Pediatric Patients with Central Nervous System Tumors

* 06-C-0213:
Tissue Procurement Protocol for the Developmental Therapeutics Clinic, National Cancer Institute (NCI)

* 06-C-0164:
A Phase II Study of BAY 43-9006 (Sorafenib) in Combination with Cetuximab (Erbitux ) in EGFR Expressing Metastatic Colorectal Cancer (CRC)

* 06-C-0051:
AIDS-Related Primary Central Nervous System Lymphoma: A Phase II Pilot Study of High-Dose Intravenous Methotrexate with Rituximab Leucovorin Rescue and Highly Active Antiretroviral Therapy

* 06-C-0014:
Prospective Evaluation of Epigenetic Alterations in Patients with Thoracic Malignancies

* 05-N-0223:
Clinical Neurophysiology: Training and Normative Values

* 05-M-0144:
MRS (Magnetic Resonance Spectroscopy) Measurement of Glutamate and GABA Metabolism in Brain

* 05-M-0105:
Investigating the Neuro-Cognitive Underpinnings of the Emotional Dysfunction Linked to Childhood Behavioral Disturbance

* 05-I-0219:
Microarray Analysis of Erythema Migrans Lesions

* 05-I-0213:
Screening and Baseline Assessment of Patients with Abnormalities of Immune Function

* 05-HG-0131:
Clinical Study of Muenke Syndrome (FGFR3-Related Craniosynostosis)

* 05-H-0242:
A Pilot Study of Alemtuzumab (Campath) in Patients with Relapsed or Refractory Severe Aplastic Anemia

* 05-H-0206:
A Pilot Study of Alemtuzumab (Campath[R]) in Patients with Myelodysplastic Syndrome (MDS)

* 05-H-0130:
Long-Term Evaluation and Follow Up Care of Patients Treated with Allogeneic Stem Cell Transplants

* 05-EI-0143:
Molecular Genetics of Retinal Degenerations

* 05-EI-0096:
Natural History and Genetic Studies of Usher Syndrome

* 05-DK-0085:
Clinical and Laboratory Investigation of Humans with Informative Iron or Erythroid Phenotypes

* 05-DK-0015:
Retinoids for Podocyte Disease

* 05-CC-0091:
Electromagnetic Tracking of Devices During Interventional Procedures

* 05-C-0170:
Randomized Phase II Study of Dose-Adjusted EPOCH-Rituximab-Bortezomib (EPOCH-R-B) Induction Followed by Bortezomib Maintenance Versus Observation in Untreated Mantle Cell Lymphoma with Microarray Profiling and Proteomics

* 05-AA-0121:
Assessment and Treatment of People with Alcohol Drinking Problems

* 04-M-0222:
Investigation of the Rapid (Next Day) Antidepressant Effects of an NMDA Antagonist

* 04-I-0286:
A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease Progression

* 04-I-0266:
Collection of Peripheral Blood, Urine, Sputum, and Bone Marrow From Healthy Donors for Use in In Vitro Research

* 04-I-0086:
Evaluation of Clinical, Virologic and Immunologic Factors that Contribute to the Pathogenesis of Chronic Hepatitis C and its Complications

* 04-HG-0211:
Procurement and Analysis of Specimens from Individuals with Pulmonary Fibrosis

* 04-HG-0127:
Clinical and Basic Investigations of Methylmalonic Acidemia (MMA) and Related Disorders

* 04-HG-0093:
Clinical and Genetic Studies on Holoprosencephaly

* 04-H-0202:
Mutations in Genes Associated with Pentalogy of Cantrell or Non-Muscle Myosin II Syndromes

* 04-H-0161:
Studies of the Natural History of Sickle Cell Disease and Other Hemolytic Disorders

* 04-H-0012:
Collection of Blood, Bone Marrow, Urine, and/or Tissue Samples from Patients with Solid Tumors, Hematological Malignancies or Non-Malignant Hematologic Disorders or HLA Compatible Family Members

* 04-EI-0008:
Clinical and Molecular Studies in Families with Corneal Dystrophy or Other Inherited Corneal Diseases

* 04-E-0053:
Environmental Polymorphism Registry (EPR)

* 04-DK-0021:
Urinary Vitamin C Loss in Subjects with and without Diabetes

* 04-CH-0250:
Event Related Potentials from Infancy to Adulthood

* 04-CH-0077:
Screening and Diagnosis of Patients with Connective Tissue Disorders

* 04-CC-0119:
Biomarkers and Protein Mass Expression Profiles in Bronchoalveolar Lavage from Patients with Lung Infiltrates

* 04-C-0281:
Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host Disease

* 04-C-0275:
Targeted Oncolytic Virotherapy and Natural History Study of KSHV-Associated Multicentric Castleman's Disease with Laboratory and Clinical Correlates of Disease Activity

* 04-C-0274:
Follow-Up of Study Subjects Previously Enrolled in Immunotherapy Studies Utilizing Gene Transfer or Other Immunotherapeutic Agents

* 04-C-0200:
Urinary and Serum VEGF and MMP Levels in Patients Receiving Radiation Therapy for Glioblastoma Multiforme: Prospective Determination of a Predictive Value for Recurrence

* 04-C-0165:
Care of Adult Oncology Patient, CCR, NCI

* 04-C-0102:
Hematologic Malignancy Biology Study

* 04-C-0055:
Allogeneic HSCT without Preparative Chemotherapy or with Low-Intensity Preparative Chemotherapy using Sirolimus and Sirolimus-Generated Donor Th2 Cells for Therapy of Refractory Leukemia, Lymphoma, Myeloma, or Myelodysplastic Syndrome

* 04-AR-0205:
Progression of Spinal Fusion in Ankylosing Spondylitis

* 03-N-0164:
Evaluation and Treatment of Neurosurgical Disorders

* 03-N-0004:
Clinical Laboratory Evaluation of Primary Chronic Autonomic Failure

* 03-M-0211:
Family Study of Affective and Anxiety Spectrum Disorders

* 03-M-0186:
The Psychobiology of Temperament: An fMRI Study

* 03-M-0185:
Generalized Anxiety Disorder and Social Anxiety Disorder: Their Impact on the Processing of Social Emotional Information and Instrumental Learning

* 03-M-0161:
The Efficacy of 17Beta-Estradiol in Postpartum-Related Depressive Illness

* 03-M-0143:
Randomized, Double-Blinded, Placebo Controlled Study of the Effects of Modafinil on Cognitive Function in Patients with Schizophrenia and Normal Controls Based on COMT Genotype

* 03-M-0138:
A Screening Protocol to Evaluate Women with Postpartum-Related Mood and Behavioral Disorders

* 03-M-0108:
Cholinergic Modulation of Cognition and Emotion in Mood Disorders: Functional Neuroimaging Studies

* 03-M-0093:
Predictability and Aversive Expectancies in Anxiety and Depressive Disorders

* 03-M-0092:
An Investigation of the Antidepressant Efficacy of an Antiglutamatergic Agent in Bipolar Depression

* 03-M-0035:
Screening, Evaluation, Diagnosis, Treatment Optimization and Follow-up for Childhood Onset Psychotic Disorders

* 03-I-0263:
VRC 200: Apheresis and Specimen Collection Procedures to Obtain Plasma, Peripheral Blood Mononuclear Cells (PBMCs) and Other Specimens for Research Studies

* 03-HG-0264:
Clinical and Molecular Investigations Into Ciliopathies

* 03-H-0280:
Disease Pathogenesis and Natural History of Lipid Disorders

* 03-H-0250:
Technical Development of Interventional Cardiovascular Magnetic Resonance Imaging

* 03-H-0170:
Non-Myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation For Severe Congenital Anemias Including Sickle Cell Disease, Thalassemia, and Diamond Blackfan Anemia

* 03-H-0168:
Natural History and Molecular Characterization of Benign Ethnic Neutropenia in Individuals of African Descent

* 03-H-0105:
The Determination of Genetic Basis Of Immunodeficiency

* 03-H-0015:
Collection of Blood from Volunteers and Patients for Studies of Endothelial Function and Systemic Inflammation

* 03-EI-0155:
Evaluation of Single Nucleotide Polymorphism (SNP) in Patients with and Subjects without Age-Related Macular Degeneration (AMD)

* 03-EI-0123:
Clinical and Molecular Studies in Families with Congenital or Hereditary Cataracts

* 03-EI-0122:
Evaluation of Immune Responses to Different Antigens in Non Infectious Ocular Inflammatory Diseases

* 03-EI-0033:
X-Linked Juvenile Retinoschisis - Clinical and Molecular Studies

* 03-E-0099:
Pathogenic Studies In Families With Twins Or Siblings Discordant For Systemic Rheumatic Disorders

* 03-DK-0257:
Effect of Leptin Therapy in the Treatment of Severe Insulin Resistance

* 03-DK-0256:
Inhibition of Intestinal Glucose Absorption by the Bioflavonoid Quercetin in the Obese and in Obese Type 2 Diabetics

* 03-DK-0098:
Study of Thyrotropin Releasing Hormone in Patients with Thyroid or Pituitary Abnormalities

* 03-CC-0128:
Development and Evaluation of Techniques for Computer Aided Detection and Diagnosis from Radiologic Images

* 03-CC-0060:
Virtual Functional Anatomy (VFA)

* 03-C-0278:
A Comparative Study of Pediatric CNS Tumor Activity as Assessed by [18]F-FDG PET Imaging and Proton Magnetic Resonance Spectroscopic Imaging ([1]H-MRSI)

* 03-C-0277:
Cell Harvest and Preparation for Surgery Branch Adoptive Cell Therapy Protocols

* 03-C-0241:
The Natural History of Childhood Malignancies Treated with Radiation Therapy

* 03-C-0145:
Evaluation of the Natural History and Management of Pancreatic Lesions Associated with Von Hippel-Lindau

* 03-C-0066:
Hereditary Leiomyomatosis Renal Cell Cancer (HLRCC): Identification of the Disease Gene and Characterization of the Predisposition to Renal Cancer

* 03-AR-0173:
Studies of the Natural History, Pathogenesis, and Outcome of Autoinflammatory Diseases (NOMID/CAPS, DIRA, CANDLE, SAVI, CRMO, Still s Disease, Behcet s Disease, and other Undifferentiated Autoinflammatory Diseases)

* 03-AR-0131:
Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal Study

* 03-AG-0325:
Longitudinal Studies of Human Physiology, Biochemistry, and Psychology (The Baltimore Longitudinal Syudy of Aging - BLSA)

* 02-N-0132:
In Vivo Mapping Of Structural and Biochemical Abnormalities In Patients With Primary Focal Dystonia

* 02-N-0014:
Research Study of Specimens Obtained During Epilepsy Surgery

* 02-M-0321:
fMRI Investigation of Explicit Cue and Contextual Fear

* 02-M-0239:
Randomized, Double-Blinded, Placebo Controlled Study of the Effects of Tolcapone and Entacapone on Cognitive Function in Patients with Schizophrenia and Normal Controls Based on COMT Genotype

* 02-M-0120:
The Efficacy of Phytoestrogens and Selective Estrogen Receptor Modulators in Perimenopause-Related Depression

* 02-M-0021:
Characterization and Pathophysiology of Severe Mood and Behavioral Dysregulation in Children and Youth

* 02-I-0286:
A Pilot Study of the Safety and Efficacy of Imatinib Mesylate in Reducing Eosinophilia in Patients with the Myeloproliferative Variant Hypereosinophilic Syndrome (HES) or Non-Myeloproliferative HES Refractory to Standard Therapy

* 02-I-0277:
Regulation of the Proliferation and Survival of Normal and Neoplastic Human Mast Cells

* 02-I-0202:
Leukapheresis Procedures to Obtain Plasma and Lymphocytes for Research Studies on Antiretroviral Naive HIV-Infected Patients

* 02-I-0147:
Genetic Studies of Chronic Active Epstein-Barr Virus Infection

* 02-I-0110:
Natural History of Anthrax: A Study of Primary Infected, Recovered, and Exposed (SPoRE) Individuals and Evaluation of AVA Vaccinated Recipients

* 02-I-0086:
Evaluation of Viral Factors and Immune Parameters to Study HIV-Specific Immunity

* 02-I-0055:
Evaluation, Treatment and Follow up of Patients with Lyme Disease

* 02-HG-0107:
Investigation of Neurodegeneration in the Glycosphingolipid Storage Disorders

* 02-H-0250:
A Phase I/II Study of HLA-matched Mobilized Peripheral Blood Hematopoietic Stem Cell Transplantation for Advanced Mycosis Fungoides/Sezary Syndrome Using Nonmyeloablative Conditioning with Campath-1H

* 02-H-0160:
Peripheral Blood Stem Cell Collection from Adult Volunteers

* 02-H-0050:
Technical Development of Cardiovascular Magnetic Resonance Imaging

* 02-CH-0311:
Investigations into Inborn Errors of Cholesterol Synthesis and Related Disorders

* 02-CH-0023:
Studies of Pediatric Patients with Metabolic or Other Genetic Disorders

* 02-CC-0266:
Acute Cardiac Allograft Cellular Rejection and Cardiac Allograft Vasculopathy: Identification of Diagnostic Biomarkers and Target Pathways for Preventive Therapy

* 02-CC-0045:
A Prospective (Cohort) Study to Identify Factors Affecting Morbidity Following the Diagnosis and Treatment of Patients With Breast Cancer: A Multi-Institutional Study between the National Institutes of Health (NIH) Rehabilitation Medicine Department (RMD

* 02-C-0313:
Cancer Risk in Xeroderma Pigmentosum Heterozygotes

* 02-C-0212:
Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer

* 02-C-0211:
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Melanoma

* 02-C-0210:
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Blood and Lymph Node Malignancy

* 02-C-0186:
Eligibility Screening of Patients with CNS Tumors for NCI Clinical Research Protocols

* 02-C-0179:
Collection of Blood, Tissue and Urine from Patients with Cancer

* 02-C-0178:
Multidisciplinary Etiologic Study of Familial Testicular Cancer

* 02-C-0159:
The Birt Hogg-Dube Syndrome: Identification of the Disease Gene and Characterization of the Predisposition of Renal Cancer

* 02-C-0077:
Characterization of High Risk Breast Duct Epithelium by Cytology, Breast Duct Endoscopy, and cDNA Gene Expression Profile

* 02-C-0064:
Collection of Peripheral Blood and/or Urine From Patients Undergoing Radiation Therapy

* 02-C-0052:
Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History Study

* 02-AR-0131:
Collection Of Blood Components Using Apheresis from Patients with Rheumatic Diseases and Healthy Volunteers

* 01-N-0206:
Phenotype/Genotype Correlations in Movement Disorders

* 01-N-0145:
Screening and Natural History: Primary Lateral Sclerosis and Related Disorders

* 01-N-0139:
Evaluation and Treatment of Patients with Epilepsy

* 01-N-0007:
Evaluation, Pathogenesis, and Treatment of Patients with or at Risk for Cerebrovascular Disease (A Natural History/Disease Pathogenesis Protocol)

* 01-M-0254:
The Evaluation of Patients with Mood and Anxiety Disorders and Healthy Volunteers

* 01-M-0232:
Positron Emission Tomography (PET) Scanning in Dopamine Disorders: Parkinson's Disease and Schizophrenia

* 01-M-0192:
Fluoxetine's Effects on Attention and Emotional Memory in Anxious and Depressed Youth and Adults

* 01-M-0185:
Effects of Arousal and Stress on Classical Conditioning

* 01-I-0238:
Diagnosis and Treatment of Leishmanial Infections

* 01-I-0226:
Evaluation of Immune Response to Vaccines in Primary Immune Disorders

* 01-I-0202:
Natural History, Genetics, Phenotype and Treatment of Mycobacterial Infections

* 01-I-0161:
Identification of Novel Viruses

* 01-HG-0109:
Natural History Study of the Clinical and Molecular Manifestations of Smith-Magenis Syndrome (SMS)

* 01-H-0198:
Clinical Course in Cystic Fibrosis: The Effects of Pseudomonas Aeruginosa and Potential Modifier Genes

* 01-H-0122:
Collection and Storage of Umbilical Cord Hematopoietic Stem Cells for Sickle Cell Disease Therapy

* 01-H-0088:
Determining the Prevalence and Prognosis of Secondary Pulmonary Hypertension in Adult Patients with Sickle Cell Anemia

* 01-DK-0062:
Genetic Analysis of Familial Keloids

* 01-DC-0229:
Genetic Analysis of Hereditary Disorders of Hearing and Balance

* 01-DC-0228:
Clinical and Molecular Analysis of Enlarged Vestibular Aqueducts

* 01-DC-0099:
Evaluation for NIDCD Head & Neck Surgery Branch Clinical Research Protocols

* 01-D-0184:
Evaluation and Treatment of Bone and Mineral Disorders

* 01-CC-0231:
A Prospective Study of Transfusion-Transmitted Infections

* 01-CC-0045:
Studies of Phlebotomy Therapy in Hereditary Hemochromatosis

* 01-C-0158:
Protocol to Assess Vascularity in Kaposi's Sarcoma Lesions Utilizing Non-Invasive Imaging Techniques

* 01-C-0157:
Eligibility Screening and Tissue Procurement for the National Cancer Institute (NCI), Pediatric Oncology Branch (POB) Clinical Research Protocols

* 01-C-0129:
Eligibility Screening and Tissue Procurement for the National Cancer Institute (NCI) Center for Cancer Research (CCR) Clinical Protocols

* 01-C-0070:
Evaluation of the Natural History of Patients with Tumors of the Central Nervous System

* 01-C-0038:
Collection of Blood, Bone Marrow, Tumor, or Tissue Samples from Patients with HIV Infection, KSHV Infection, Viral-Related Pre-Malignant Lesions, and/or Cancer

* 01-C-0030:
Short-Course EPOCH-Rituximab for Untreated CD-20+ HIV-Associated Lymphomas

* 01-AR-0227:
Studies of the Natural History of Rheumatic Disease in Minority Communities

* 00-N-0158:
Trial of Intracerebral Infusion in Patients with Medically Intractable Epilepsy

* 00-N-0089:
Genetic Analysis of the Chiari I Malformation

* 00-N-0082:
Characterization of Brain Morphology and Activity Using Functional and Anatomical MRI Contrast

* 00-N-0043:
Clinical and Molecular Manifestations of Inherited Neurological Disorders

* 00-M-0198:
The Phenomenology and Neurophysiology of Affective Dysregulation in Children and Adolescents with Bipolar Disorder

* 00-M-0085:
Structural and Functional Imaging of Neuropsychiatric Patients and Normal Volunteers with 3.0 Tesla MRI and Magnetoencephalography

* 00-I-0159:
Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)

* 00-I-0099:
Langherhans' Cell Function and Inflammatory Responses in Skin of Volunteers Using the Suction Blister Technique

* 00-HG-0209:
Molecular and Clinical Studies of Primary Immunodeficiency Diseases

* 00-HG-0153:
Investigations into Chediak-Higashi Syndrome and Related Disorders

* 00-HG-0141:
Clinical, Biochemical, and Molecular Investigations into Alkaptonuria

* 00-HG-0058:
Genetic Analysis of Attention Deficit Hyperactivity Disorder (ADHD)

* 00-H-0051:
Cutaneous Tumorigenesis in Patients with Tuberous Sclerosis

* 00-DK-0221:
Evaluation of the Immune Response in Humans After Exposure to Hepatitis C Virus

* 00-DK-0107:
Search for Novel Methods to Detect Acute Renal Failure

* 00-DC-0073:
Identification of Hereditary Auditory Temporal Processing Deficits

* 00-CH-0180:
Endocrine Studies in Health and Disease

* 00-CH-0160:
Clinical and Molecular Analysis of ACTH-Independent Steroid Hormone Production in Adrenocortical Tissue

* 00-CH-0127:
Evaluation of Patients with Endocrine-Related Conditions

* 00-CH-0093:
Diagnosis, Pathophysiology, and Molecular Biology of Pheochromocytoma and Paraganglioma

* 00-CC-0165:
Filgrastim-Mobilized Peripheral Blood Stem Cells for Primary Allogeneic Transplantation Using Unrelated Donors Participating in the National Marrow Donor Program (NMDP)

* 00-C-0181:
Evaluation for NCI Radiation Oncology Branch Clinical Research Protocols

* 00-C-0078:
Collection of Blood, Bone Marrow, Tumor, or Tissue Samples from Patients with Cancer or Normal Volunteers

* 00-C-0074:
Evaluation of Late Effects and Natural History of Disease in Patients Treated with Radiotherapy

* 00-AR-0222:
Studies of the Pathogenesis and Natural History of Arthritis and Related Conditions

* 99-M-0172:
Integrating EEG/MEG and fMRI: Activity Correlation between Frontal and Temporal Lobe Structures in Schizophrenic Patients, Their Siblings and Unrelated Normal Volunteers

* 99-I-0084:
Studies of Human Pneumocystis Infection

* 99-H-0076:
Fiberoptic Bronchoscopy in Patients with Asthma

* 99-H-0050:
Non-Myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematologic Malignancies in High Risk Patients and in Patients with Debilitating Hematologic Diseases

* 99-H-0037:
Apheresis of Family Members of Patients Undergoing Allogeneic Bone Marrow Transplantation. A Pre-Clinical Study of Selective Depletion of Donor Lymphocytes to Prevent Acute Graft-Versus-Host Disease

* 99-DK-0002:
Diabetes and Heart Disease Risk in Blacks

* 99-CH-0103:
Evaluation of Women with Endocrine and Reproductive-Related Conditions

* 99-CH-0055:
New Imaging Modalities in the Evaluation of Patients with Ectopic Cushing's Syndrome

* 99-CC-0168:
Collection and Distribution of Blood Components from Healthy Donors for In Vitro Research Use

* 99-C-0128:
Evaluation for NCI Surgery Branch Clinical Research Protocols

* 99-C-0099:
Examination of Clinical and Laboratory Abnormalities in Patients with Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy

* 99-AR-0004:
Molecular Basis of Primary Immunodeficiencies

* 98-N-0047:
Immuno-Virological Evaluation of Human T Cell Leukemia Virus Type-1 Associated Myelopathy (HAM/TSP)

* 98-I-0027:
The Characterization of CD34+ Derived Mast Cell Precursors Mobilized by Administration of Granulocyte Colony Stimulating Factor and Plerixafor

* 98-HG-0249:
Genetic Analysis of Brain Disorders

* 98-H-0062:
Role of Exotoxins in the Pathogenesis of Pseudomonas Aeruginosa

* 98-D-0145:
Screening and Natural History of Patients with Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome

* 98-CH-0081:
Clinical and Basic Investigations into Smith-Lemli-Opitz Syndrome

* 98-CC-0090:
Evaluation of Hematologic Patients - Training Protocol

* 98-CC-0019:
Normal Volunteer Scanning on MR

* 98-C-0037:
Treatment of Children with Cancer

* 98-AA-0056:
Functional Neuroanatomy of Positive and Negative Affect in Alcoholics and Non-Alcoholics

* 98-AA-0009:
Screening Evaluation for NIAAA Protocols

* 97-I-0191:
Studies of Lymphocyte Kinetics Using Stable Isotopes

* 97-I-0096:
Evaluation, Treatment, and Monitoring of Patients With Known or Suspected Parasitic Infection

* 97-H-0061:
Evaluation and Treatment of Pulmonary Patients not Participating in Research (Training Protocol)

* 97-H-0041:
Screening Protocol for Subjects Being Evaluated for Hematology Branch Protocols

* 97-H-0022:
Bronchoscopy in Patients with Pulmonary Diseases and Research Volunteers

* 97-DC-0057:
Genetic Studies of Stuttering

* 97-CH-0076:
A Clinical and Genetic Investigation of Pituitary Tumors and Related Hypothalmic Disorders

* 97-CH-0064:
Evaluation and Intervention for Ambulation, Growth, and Basilar Invagination in Osteogenesis Imperfecta

* 97-C-0147:
Collection of Serum and Tissue Samples from Patients with Biopsy-Proved or Suspected Malignant Disease

* 97-C-0143:
Collection of Blood, Bone Marrow and Tissue Samples for the Investigation of the Human Immune Response, Lymphoma Biology and HTLV-1 Infection

* 96-I-0129:
Evaluation and Long Term Follow-up of Patients with Allergic and Inflammatory Disorders

* 96-I-0052:
A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients with Suspected Chronic Lyme Infection and Selected Control Populations

* 96-H-0100:
Role of Genetic Factors in the Pathogenesis of Lung Disease

* 96-H-0049:
Use of Granulocyte Colony Stimulating Factor (G-CSF) Mobilized Leukapheresis Collections from Healthy Volunteers to Develop Improved Methods of Stem Cell and Lymphocyte Selection for Allogeneic Transplantation

* 96-C-0102:
Evaluation and Treatment of Subjects with Dermatologic Diseases

* 96-C-0097:
The Acquisition of Blood and Skin Samples from Patient Volunteers to Support Research Activities on Dermatologic and Other Diseases

* 96-C-0071:
Follow-up for Patients Previously Enrolled on the Center for Cancer Research Protocols

* 95-M-0150:
A Neurobiological Investigation of Patients with Schizophrenia Spectrum Disorders and Their Siblings

* 95-M-0097:
An Endocrine Model for Postpartum Mood Disorders

* 95-I-0066:
Genetic Analysis of Immune Disorders

* 95-I-0027:
Virologic and Immunologic Evaluation of Lymph Node, Tonsillar, and Intestinal Biopsies, and Bronchoalveolar Lavage Fluid

* 95-HG-0193:
Clinical and Basic Investigations into Hermansky-Pudlak Syndrome

* 95-H-0186:
Characterization of the Pathogenesis of Lymphangioleiomyomatosis (LAM)

* 95-H-0047:
Diagnosis and Treatment of Patients with Heart and Vascular Disease (Training Protocol)

* 95-CH-0059:
Definition of the Genotype and Clinical Phenotype of Primary Pigmented Nodular Adrenocortical Disease (PPNAD), Carney Complex, Peutz-Jeghers Syndrome and Related Conditions

* 94-I-0079:
Eosinophil Activation and Function in Parasitic Infections and Other Conditions with Increased Tissue or Peripheral Blood Eosinophilia in Humans

* 94-I-0073:
Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells

* 94-HG-0193:
Genetic and Clinical Studies of Congenital Anomaly Syndromes

* 94-HG-0132:
The Phenotype and Etiology of Proteus Syndrome and Related Overgrowth Disorders

* 94-HG-0105:
Genetics and Pathophysiology of Familial Mediterranean Fever and Related Disorders

* 94-H-0010:
Evaluation, Treatment and Training Protocol for Patients with Bone Marrow Failure States, Isolated or Multilineage Cytopenias, Metastatic Solid Tumors, or Hematologic Malignancies

* 94-E-0165:
Studies in the Natural History and Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory Myopathies

* 94-DK-0133:
Genetic Markers for Focal Segmental Glomerulosclerosis

* 94-DK-0127:
Pathogenesis of Glomerulosclerosis

* 94-D-0018:
Salivary Evaluation in Healthy Volunteers

* 94-C-0074:
Treatment and Natural History Study of Lymphomatoid Granulomatosis

* 94-AR-0066:
Studies of the Pathogenesis and Natural History of Systemic Lupus Erythematosus (SLE)

* 93-N-0202:
Diagnosis and Natural History Protocol for Patients with Different Neurological Conditions

* 93-M-0170:
Regional Cerebral Blood Flow Studies of Object Perception, Identification, Localization, and Memory

* 93-I-0119:
Detection and Characterization of Host Defense Defects

* 93-I-0106:
Genetic Susceptibility to Cryptococcal and Other Systemic Fungal Infections in Adults

* 93-I-0086:
Evaluation and Long Term Follow Up of Patients with Acute or Chronic Inflammatory Disorders

* 93-I-0063:
Study of the Immunopathogenesis, Natural History, and Genetics of Autoimmune Lymphoproliferative Syndrome (ALPS) Associated with an Expansion of CD4-8-/TCR alpha/beta+ T Cells

* 93-I-0057:
Apheresis Procedures to Obtain Plasma or Leukocytes for In Vitro Studies

* 93-DK-0127:
Family Studies in Metabolic Diseases and Mineral Metabolism

* 93-C-0133:
Dose-Adjusted EPOCH Chemotherapy and Rituximab (CD20+) in Adults and Children with Previously Untreated Patients with Aggressive Non-Hodgkin's Lymphoma

* 92-M-0174:
The Central Nervous System Effects of Pharmacologically Induced Hypogonadotropic Hypogonadism with and without Estrogen and Progesterone Replacement

* 92-I-0125:
A Study of Viral Burden in Peripheral Blood Versus Lymphoid and Bone Marrow Tissue in HIV-Infected Individuals

* 92-EI-0113:
Immunopathology and Molecular Pathology of Ocular Diseases in Humans

* 92-DK-0156:
Studies of Immunologically-Mediated Kidney Diseases

* 92-DK-0033:
Pharmacokinetics and Biodistribution of Ascorbic Acid in Healthy Human Subjects

* 92-DC-0178:
Multimodal Studies of Language Production and Comprehension in Normal Volunteers and Patients with Neurologically-Based Language Impairments

* 91-I-0140:
Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Reproductive Fluids in HIV-Infected and HIV-Uninfected Volunteers

* 91-DK-0214:
Evaluation of Patients with Liver Disease

* 91-DK-0085:
Studies of Hyperparathyroidism and Related Disorders

* 91-DK-0066:
Fasting Hypoglycemia: Diagnosis and Treatment

* 91-CC-0117:
Epidemiology, Infectivity and Natural History of Hepatitis C Virus Infection in a Blood Donor Population

* 91-AR-0196:
Studies on the Natural History and Pathogenesis of Polymyositis, Dermatomyositis, and Related Diseases

* 90-M-0142:
Brain Procurement for the Human Brain Collection Core

* 90-M-0088:
The Treatment of Menstrually-Related Mood Disorders with the Gonadotropin Releasing Hormone (GnRH) Agonist, Depot Leuprolide Acetate (Lupron)

* 90-M-0014:
Studies of Frontal Lobe Function During Cognitive Stimulation as Measured with Oxygen-15 Water Positron Emission Tomography in Normal Subjects and Patients with Neuropsychiatric Disorders

* 90-I-0120:
Comparison of Inflammatory Responses in Normal Volunteers and Patients with Abnormal Phagocyte Function Using the Suction Blister Technique

* 90-CC-0168:
A Rigid Body Database on Human Movement

* 89-N-0045:
Evaluation of Progression in Multiple Sclerosis by Magnetic Resonance Imaging (MRI)

* 89-M-0160:
Inpatient Evaluation of Neuropsychiatric Patients

* 89-M-0006:
Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Controls

* 89-I-0158:
Studies of Immune Regulation in Patients with Common Variable Immunodeficiency and Related Humoral Immunodeficiency Syndromes

* 89-DK-0173:
Studies of States with Resistance to Vitamin D and Parathyroid Hormone

* 89-DK-0152:
Determination of Glomerular Filtration Rate, Effective Renal Plasma Flow and Glomerular Capillary Wall Permselectivity

* 89-C-0086:
Clinical Manifestations and Molecular Bases of Heritable Urologic Malignant Disorders

* 88-M-0131:
The Evaluation of Women with Perimenopause-Related Mood and Behavioral Disorders

* 88-I-0083:
Host Response to Infection and Treatment in the Filarial Diseases of Humans

* 87-I-0163:
Apheresis Procedures to Obtain Plasma or Leukocytes for In Vitro Studies

* 87-DK-0029:
Diagnosis and Treatment of Patients with Cystic Fibrosis and Other Disorders of the Respiratory System and Pancreas

* 87-CC-0091:
Magnetic Resonance Imaging at 1.5 and 3.0 Tesla

* 86-HG-0096:
Studies of Genetic Heterogeneity in Patients with Lysosomal Storage Disorders

* 85-N-0195:
A Training Protocol for the use of Botulinum Toxin in the Treatment of Neurological Disorders

* 85-I-0127:
Treatment of Cysticercosis including Neurocysticercosis with Praziquantel, Albendazole and other Novel Treatment Modalities

* 85-DK-0082:
Acromegaly Treatment and Natural History

* 84-M-0050:
Biochemical, Physiological, and Psychological Measures in Normal Controls and Relatives of Psychiatric Patients

* 84-D-0056:
Evaluation of Salivary Gland Dysfunction

* 83-C-0022:
Psychological Benefits of a Normalized Camping Experience for Children with Cancer

* 82-I-0183:
Study of the Immune Regulation of Idiopathic Inflammatory Bowel Diseases: Crohn's Disease, Ulcerative Colitis, and Other Inflammatory Conditions of the Gut

* 82-H-0032:
Comprehensive Evaluation of the Etiology and Pathogenesis of Chronic Lung Disease (Screening Protocol)

* 81-M-0126:
The Evaluation of Women with Menstrually Regulated Mood and Behavioral Disorders

* 81-I-0164:
Apheresis Procedures to Obtain Plasma or Lymphocytes for In Vitro Studies

* 80-M-0083:
Bipolar Genetics: A Collaborative Study

* 79-H-0100:
Teaching Protocol for the Evaluation of Plasma Lipoproteins

* 78-I-0023:
Diagnosis and Management of Inflammatory and Infectious Diseases

* 78-HG-0093:
Natural History Study of the Use of Cysteamine in the Treatment of Cystinosis

* 78-C-0039:
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Cancer

* 77-I-0094:
Study of Patients with Parasitic Infections of the Gastrointestinal Tract

* 77-DK-0096:
Studies on Thyroid Nodules and Thyroid Cancer

* 77-DK-0002:
Evaluation of Patients with Thyroid Function Disorders

* 76-HG-0238:
Diagnosis and Treatment of Patients with Inborn Errors of Metabolism or Other Genetic Disorders

* 76-H-0051:
Lipoprotein Metabolism in Normal Volunteers and Hyperlipoproteinemic Patients

* 76-DK-0006:
Studies of Molecular Genetics of Insulin Secretion, Insulin Action, and Diabetes Mellitus

Active Followup, Protocols NOT Recruiting New Patients 

* 14-NR-0032:
An Investigation of the Biological and Neuronal Mechanisms of Post-Traumatic Stress Disorder, Depression and Post-Concussive Syndrome Onset Following a Traumatic Brain Injury

* 14-N-0083:
Neural Basis of Decision Making Deficits in Traumatic Brain Injury

* 14-I-0091:
Analysis of Patients Treated for Chronic Granulomatous Disease Since January 1, 1995

* 14-HG-0038:
Treatment of SCID due to ADA Deficiency with Autologous Transplantation of Cord Blood or Hematopoietic CD 34+ Cells after Addition of a Normal Human ADA cDNA by the EFS-ADA Lentiviral Vector

* 14-H-0202:
A Phase II Trial of Losartan to Reverse Sickle Nephropathy

* 14-H-0182:
Phase I/II Trial of Early Infusion of Multivirus Specific T cells (MVST) to Prevent Post Transplant Viral Infections

* 14-H-0155:
A Phase 1 Study Evaluating Gene Therapy by Transplantation of Autologous CD34+ Stem Cells Transduced Ex Vivo with the LentiGlobinA BB305 Lentiviral Vector in Subjects with Severe Sickle Cell Disease

* 14-H-0130:
Observational Study for Detecting Kidney Damage in Patients with Sickle Cell Disease

* 14-DK-0154:
Metabolic and Neural Adaptations to Weight Loss, Plateau, and Regain

* 14-DK-0012:
Expanded-Access Single Named-Patient Guidance Document for the Use Of BMS 650032 (Asunaprevir; ASV) in Combination with Daclatasvir for the Treatment of a Patient with Recurrent Hepatitis C Virus (HCV) Infection

* 14-C-0198:
A Multicenter Study of Ibrutinib and Lenalidomide in Combination with DA-EPOCH-R in Subjects with Relapsed or Refractory Diffuse Large B-cell Lymphoma

* 14-C-0131:
A Phase II, Open-Label Study in Patients with BRAF V600E-Mutated Rare Cancers with Several Histologies to Investigate the Clinical Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib

* 14-C-0007:
Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults with Desmoid Tumors/Aggressive Fibromatosis

* 13-I-0075:
Sildenafil in Patients with Pulmonary Nontuberculous Mycobacterial Infection

* 13-I-0020:
Elucidation of the Mucosal Immune Responses to Live Attenuated Influenza Vaccine In Healthy Adults

* 13-H-0130:
Pilot Study of Strength Testing in Overweight Women With or Without Insulin Resistance

* 13-DK-0138:
A Phase 2, Multicenter, Double-Blind, Parallel Dosing, Randomized Study of Fresolimumab or Placebo in Patients with Steroid-Resistant Primary Focal Segmental Glomerulosclerosis

* 13-DK-0136:
A Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Multiple Dose, 2-Period Crossover Study to Evaluate the Effect of RM-493 on Energy Expenditure in Obese Subjects

* 13-DK-0013:
Impact of Chronic Cold Exposure on Energy Metabolism in Humans

* 13-CH-0023:
A Phase 2 Pilot Study to Characterize and Examine the Pharmacokinetics and Disease Bio-Marker Response of Chronocort in Adults with Congenital Adrenal Hyperplasia

* 13-CC-0098:
A Pilot Dosing Study for Gadofosveset Trisodium (Ablavar) for Coronary Magnetic Resonance Angiography (MRA)

* 13-C-0128:
Collection of Saliva from Healthy Volunteers for Research

* 13-C-0106:
A Pivotal Multicenter Trial of Moxetumomab Pasudotox in Relapsed/ Refractory Hairy Cell Leukemia

* 13-C-0018:
PET Imaging Of Renal Cell Carcinoma With 18F-VM4-037: A Phase II Pilot Study For Detection Of Disease And Correlation With VHL Mutation Status

* 12-N-0104:
Validating a New Writer's Cramp Scale

* 12-I-0077:
Influenza A 2009 H1N1 Human Challenge Study in Healthy Adult Volunteers

* 12-HG-0207:
A Phase 1 Randomized, Placebo-Controlled, Double-Blind, Escalating Single-Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ManNAc in Subjects with GNE myopathy or Hereditary Inclusion Body Myopathy (HIBM)

* 12-HG-0161:
Therapeutic Trial of EPI -743 In Patients with Disorders of Energy Utilization or Oxidation-Reduction

* 12-H-0127:
A Phase 1, Placebo-Controlled, Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Escalating, Single or Multiple Oral Doses of Aes-103 in Subjects with Stable Sickle Cell Disease

* 12-H-0103:
Characterization of Innate Immune Responses to MF59 Adjuvanted H5N1 Vaccine Compared to Non-adjuvanted H5N1 Vaccine

* 12-H-0092:
An Intravenous, Open-Label, Single-Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of rhLCAT in Patients with Stable Coronary Artery Disease

* 12-H-0070:
A Pilot Two-Step Phase II Study of the Oral Gold Compound Auranofin in Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)/Prolymphocytic Lymphoma (PLL)

* 12-H-0052:
Prospective Randomized Trial on Radiation Dose Estimates of CT Angiography in Patients Applying Iterative Image Reconstruction Techniques

* 12-H-0035:
A Phase II Study of PCI-32765 for Patients with Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) Who Need Therapy and are Older than 65 or have a 17p Deletion

* 12-H-0028:
Peripheral Blood Stem Cell Allotransplantation for Hematological Malignancies Using Ex Vivo CD3, CD19 Depletion and CD34 Selection

* 12-H-0010:
A Phase I Study of Bone Marrow Stromal Cell Infusions to Treat Acute Graft Versus Host Disease, Marrow Failure and Tissue Injury After Allogeneic Stem Cell Transplantation

* 12-EI-0167:
A Phase I/II Study of the NT-501 Intraocular Implant Releasing Ciliary Neurotrophic Factor (CNTF) in Participants with CNGB3 Achromatopsia

* 12-EI-0134:
A Phase II Randomized Study to Compare Anti-VEGF Agents in the Treatment of Diabetic Macular Edema (CADME)

* 12-CH-0062:
Investigations into ISCU Myopathy or Iron Sulfur Scaffold U Protein Myopathy

* 12-CH-0051:
Brain-Derived Neurotrophic Factor in Obesity and Neurocognitive Function

* 12-CH-0011:
Non-Invasive Study of Brain Connectivity Using Combined EEG and NIRS

* 12-CC-0186:
A Phase 2a Study of an Anti-LOXL2 Monoclonal Antibody (GS-6624) in HIV and/or Hepatitis C-infected Subjects with Liver Fibrosis

* 12-CC-0017:
The Influence of Atazanavir-ritonavir and Efavirenz on Atovaquone Pharmacokinetics in HIV-infected Volunteers

* 12-C-0208:
Phase 1 Dose Escalation Study of Sorafenib and Irinotecan Combination Therapy in Pediatric Patients with Relapsed or Refractory Solid Tumors

* 12-C-0192:
Lenalidomide Maintenance Therapy in Multiple Myeloma: A Phase II Clinical and Biomarker Study

* 12-C-0191:
Phase II Open Label Non-Randomized Single Agent Study of the SMAC (Second Mitochondrial-Derived Activator of Caspases)-Mimetic Birinapant (TL32711; NSC 756502) in Relapsed Platinum Resistant or Refractory Epithelial Ovarian Cancer, Primary Peritoneal

* 12-C-0187:
A Phase I/II Study of ISIS 183750 in Combination with Irinotecan in Irinotecan-refractory Colorectal Cancer

* 12-C-0177:
A Phase I and Pharmacokinetic Single-Agent Study of Romidepsin in Patients With Lymphomas, Chronic Lymphocytic Leukemia, and Select Solid Tumors, and Varying Degrees of Liver Dysfunction

* 12-C-0166:
A Phase II Study of Cabazitaxel in Patients with Urothelial Carcinoma Who Have Disease Progression Following Platinum-Based Chemotherapy

* 12-C-0155:
Acceptance and Commitment Therapy for Adolescents and Adults with Neurofibromatosis Type 1 and Chronic Pain: A Pilot Study

* 12-C-0114:
A Pilot Trial of the Combination of Vemurafenib with Adoptive Cell Therapy in Patients with Metastatic Melanoma

* 12-C-0098:
A Phase II Study of the Raf Kinase and Receptor Tyrosine Kinase Inhibitor Sorafenib (IND# 69896) in Children and Young Adults with Relapsed / Refractory Rhabdomyosarcoma, Wilms Tumor, Hepatocellular Carcinoma, and Papillary Thyroid Carcinoma

* 12-C-0056:
An Open Label Phase I Study to Evaluate the Safety and Tolerability of GI-6301 Vaccine Consisting of Whole, Heat-Killed Recombinant Saccharomyces Cerevisiae (Yeast) Genetically Modified to Express Brachyury Protein in Adults with Solid Tumors

* 12-C-0045:
Phase II Study in Patients with Metastatic Melanoma Using a Non-Myeloablative Lymphocyte Depleting Regimen of Chemotherapy Followed by Infusion of MART-1 Reactive Peripheral Blood Lymphocytes (PBL) With or Without High Dose Aldesleukin

* 12-C-0004:
A Randomized Phase I/II Study of ABT-888 in Combination with Temozolomide in Recurrent (Temozolomide Resistant) Glioblastoma

* 12-AA-0032:
Measuring Effects of Acute Ethanol on Human Brain Metabolites using Magnetic Resonance Spectroscopy

* 11-N-0261:
Evaluation of Skeletal Muscle, Cardiac, and Diaphragm Imaging Biomarkers for GSK2402968 Effects in Ambulatory Boys with Duchenne Muscular Dystrophy

* 11-N-0210:
NIB Repository Protocol

* 11-N-0171:
Effect of Functional Exercise in Patients with Spinal and Bulbar Muscular Atrophy

* 11-M-0058:
A Placebo-Controlled Trial of Intravenous Immunoglobulin (IVIG) for PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections)

* 11-HG-0238:
Weight Management Interactions in a Virtual Clinical Environment

* 11-H-0268:
The Safety and the Tolerability of Ultra Low Dose Interleukin-2 in Healthy Volunteers

* 11-H-0224:
Contrast-Enhanced Ultrasound Imaging of Carotid Plaque Neovascularization

* 11-EI-0244:
A Pilot Phase I/II Study for the Evaluation of Dextromethorphan as a Microglia Inhibitor in the Treatment of Diabetic Macular Edema (MiDME2)

* 11-DK-0256:
Pharmacokinetic and Pharmacodynamic Studies of Liothyronine. A Study on the Metabolic Effects of Thyroid Hormone

* 11-CH-0119:
Adrenal Hyperplasia Among Young Patients with Polycystic Ovarian Syndrome

* 11-CH-0078:
Evaluation of Cortisol Resistance in Young Endurance-Trained and Elderly Men

* 11-CC-0265:
A Pilot Study to Examine Physiological and Clinical markers of Chronic Stress in Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

* 11-CC-0201:
The Effect of Music Listening on the Amount of Opioids Used in Surgical Intensive Care Patients

* 11-CC-0137:
Testing Subjects with Traumatic Brain Injury using Haptic Technology

* 11-CC-0131:
Phase Ib Study of the Safety and Pharmacokinetics of Chemoembolization with Irinotecan-Eluting Beads for the Treatment of Hepatic Metastases

* 11-CC-0088:
Effect of Aerobic Exercise Training on Cardiorespiratory Function in Patients with Traumatic Brain Injury

* 11-CC-0063:
Evaluating Supportive Care for Children with Cancer: A Multi-Institutional Survey Study of Pediatric Oncology Patients and Parents

* 11-CC-0037:
Mobility Training to Improve Motor Behavior in Toddlers with or at Risk for Cerebral Palsy - A Pilot Study

* 11-C-0267:
A Phase 2, Randomized, Multicenter, Open-Label Study of the Efficacy and Immune Response of the Sequential Adminstration of GVAX Pancreas Vaccine (with Cyclophosphamide) Alone or Followed by CRS-207 in Adults with Metastatic Pancreatic Adenocarcinoma

* 11-C-0250:
A Phase 1, Open-Label, Dose Escalation Study to Evaluate Safety, Pharmacokinetics and Pharmacodynamics of Combined Oral C-Met/ALK Inhibitor (PF-02341066) and Pan-Her Inhibitor (PF-0299804) in Patients with Advanced Non-Small Cell Lung Cancer

* 11-C-0232:
A Phase I/II Study of the Histone Deacetylase (HDAC) Inhibitor LBH589 (Panobinostat) in Combination with mTOR Inhibitor RAD001 (Everolimus) in Patients with Relapsed Multiple Myeloma or Lymphoma

* 11-C-0226:
Targeted Theraphy of Bronchiolitis Obliterans Syndrome (BOS)

* 11-C-0221:
Carfilzomib, Lenalidomide, and Dexamethasone in Newly Diagnosed Multiple Myeloma: Clinical and Correlative Phase II Study

* 11-C-0181:
A Phase II Study of TRC105 in Patients with Hepatocellular Carcinoma (HCC) Who Have Progressed on Sorafenib

* 11-C-0162:
A Multicenter, Open-Label, Phase 2, Safety and Efficacy Study of the Bruton's Tyrosine Kinase (Btk) Inhibitor, PCI-32765, in Subjects with Relapsed or Refractory De Novo Diffuse Large B-Cell Lymphoma

* 11-C-0159:
A Feasibility Trial Using Molecular-Guided Therapy for the Treatment of Patients with Refractory or Recurrent Neuroblastoma

* 11-C-0158:
MR Image Guided Focal Therapy in Prostate Cancer

* 11-C-0150:
Phase I Study of the Hsp90 Inhibitor, PU-H71, in Patients with Refractory Solid Tumors and Low-Grade Non-Hodgkin's Lymphoma

* 11-C-0132:
Understanding the Psychosocial Needs of Parents Who Have Lost a Child to Cancer

* 11-C-0130:
A Phase II Study of TRC105 in Adults with Advanced/Mestastic Urothelial Carcinoma

* 11-C-0123:
Prospective Randomized Study of Cell Transfer Therapy for Metastatic Melanoma Using Tumor Infiltrating Lymphocytes Plus IL-2 Following Non-Myeloablative Lymphocyte Depleting Chemo Regimen Alone or in Conjunction with 12Gy Total Body Irradiation (TBI)

* 11-C-0122:
Phase I Trial of AZD8055, An Oral MTOR Kinase Inhibitor, for Adults with Recurrent Gliomas

* 11-C-0117:
Pilot Study of the Combination of MK-2206, an AKT Inhibitor, and AZD6244, a MEK Inhibitor, in Patients with Advanced Colorectal Carcinoma

* 11-C-0115:
Phase 2 Study of Bevacizumab in Children and Adults with Neurofibromatosis Type 2 and Symptomatic Vestibular Schwannoma

* 11-C-0111:
Adjuvant Allogeneic Tumor Cell Vaccine with Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Sarcomas, Melanomas, Germ Cell Tumors, or Epithelial Malignancies Metastatic to Lungs, Pleura, or Mediastinum

* 11-C-0099:
Regional Chemotherapy in Locally Advanced Pancreatic Cancer: RECLAP Trial

* 11-C-0098:
Evaluation of Ferumoxytol Enhanced MRI for the Detection of Lymph Node Involvement in Prostate Cancer

* 11-C-0080:
Ph II Randomized Trial of the Combination of ABT-888 with Metronomic Oral Cyclophosphamide in Refractory BRCA-Pos Ovarian, Primary Peritoneal or Ovarian High-Grade Serous Carcinoma, Fallopian Tube Cancer, Triple-Neg Breast Cancer, and Low-Grade NHL

* 11-C-0077:
Phase II Study of Oral PHA-848 125AC in Patients with Malignant Thymoma Previously Treated with Multiple Lines of Chemotherapy

* 11-C-0075:
A Phase 1 Study of AZD6244 in Combination with Cetuximab in Refractory Solid Tumors

* 11-C-0047:
A Phase I Trial and Pharmacokinetic Study of the Oral Platinum Analog Satraplatin in Children and Young Adults with Refractory Solid Tumors including Brain Tumors

* 11-C-0044:
Frequency of Epidermal Growth Factor Receptor Mutations in Latinos/Hispanics with Non-Small Lung Cancer

* 11-C-0038:
A Phase 2 Study of Vorinostat in Subjects with Locally Advanced, Recurrent or Metastatic Adenoid Cystic Carcinoma (ACC) (IND 71976)

* 11-C-0036:
A Pilot Study of Inpatient Hospice with Procurement of Brain Tumor Tissue on Expiration for Research Purposes

* 11-C-0033:
Extended Follow-up of High Ovarian Cancer Risk Cohort from 02-C-0268 (GOG-199)

* 11-C-0029:
Phase I Study of the HSP-90 Inhibitor, AT13387, in Adults with Refractory Solid Tumors

* 11-C-0024:
A Phase II Trial of IPH2101 (Anti-KIR) in Smoldering Multiple Myeloma (SMM)

* 11-C-0021:
A Pilot Study of F-18 Sodium Fluoride PET/CT for Metastatic Burden Qualification in Prostate Cancer

* 11-C-0020:
A Pilot Study of Novel Imaging Modalities in Monoclonal Gammopathy of Undetermined Significance (MGUS), Smoldering Multiple Myeloma (SMM), and Multiple Myeloma (MM)

* 11-C-0011:
Phase I/II Study of Metastatic Melanoma Using Lymphodepleting Conditioning Followed by Infusion of Tumor Infiltrating Lymphocytes Genetically Engineered to Express IL-12

* 11-AR-0241:
A Pilot Study of Anakinra in Behcet's Disease (BD)

* 11-AA-0010:
Corticotropin-Releasing Hormone Receptor 1 (CRH1) Antagonism in Anxious Alcoholics

* 10-NR-0128:
Relationship between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy

* 10-N-0193:
Using Positron Emission Tomography (PET) to Predict Intracranial Tumor Growth in Neurofibromatosis Type II (NF2) Patients

* 10-N-0121:
Oxidative Stress in Motor Neuron Disease: COSMOS-PLS Add-On Study

* 10-M-0049:
Effects of a CRF1 Receptor Antagonist on Human Startle in Normal Female Volunteers

* 10-I-0100:
A Pilot Study Using Anakinra/Kineret for the Treatment of Patients with Severe Atopic Dermatitis

* 10-I-0080:
Cardiovascular Radiologic and Metabolic Assessment in HIV: An Investigation of Pathophysiology

* 10-HG-0076:
Mothers' Thoughts About What Their Children Eat

* 10-H-0176:
Cyclophosphamide Plus Cyclosporine in Treatment-Naive Severe Aplastic Anemia

* 10-H-0031:
THE IMPROVE TRIAL: Improving Pain Management and Outcomes with Various Strategies of Patient-Controlled Analgesia (PCA)

* 10-DK-0187:
Duration of Long-Term Immunity After Hepatitis B Virus Immunization

* 10-DK-0064:
Effects of Caloric Restriction Alone versus Postoperative Caloric Restriction Following Bariatric Surgery on Glucose Metabolism in Patients with Diabetes Mellitus

* 10-DK-0002:
Partners for Better Health in Adolescent Type 2 Diabetes: The Buddy Study

* 10-DC-0211:
Connectivity Analysis for Investigation of Auditory Impairment in Epilepsy

* 10-D-0020:
The Molecular Anatomy of Oral Wound Healing

* 10-CH-0022:
Exome Sequencing in Autistic Spectrum Disorder Patients with Altered Cholesterol Homeostasis

* 10-CC-0150:
Effects of Rapid-Resisted Exercise on Ambulatory Adults with Traumatic Brain Injury

* 10-C-0220:
Phase I Trial to Evaluate the Safety, Activity and Pharmacokinetics of Marqibo (Vincristine Sulfate Liposomes Injection) in Children and Adolescents with Refractory Cancer

* 10-C-0218:
Randomized Phase II Study of AZD6244 MEK-Inhibitor with Erlotinib in KRAS Wild Type and KRAS Mutant Advanced Non-Small Cell Lung Cancer

* 10-C-0189:
A Phase 1, Dose Escalation Study of MGAH22 (Fc-Optimized Chimeric Anti-HER2 Monoclonal Antibody) in Patients with Refractory HER2 Positive Breast Cancer and Patients with Other HER2 Positive Carcinomas for Whom no Standard Therapy is Available

* 10-C-0181:
Phase 1 Dose-Escalation Study of Bruton s Tyrosine Kinase (Btk) Inhibitor PCI-32765 in Recurrent B Cell Lymphoma

* 10-C-0146:
Phase II Study of IMC-A12 in Patients with Mesothelioma Who Have Been Previously Treated with Chemotherapy

* 10-C-0114:
A Phase II Study of Bevacizumab and Erlotinib in Subjects with Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell Cancer

* 10-C-0096:
Natural History Study of Monoclonal Gammopathy of Undetermined Significance (MGUS) and Smoldering Myeloma (SMM)

* 10-C-0089:
Phase II Study of Oral PHA-848125AC in Patients with Thymic Carcinoma Previously Treated with Chemotheraphy

* 10-C-0079:
A Phase 2 Study of AZD6244 in Multiple Myeloma

* 10-C-0078:
A Pilot Study of F-18 Paclitaxel (FPAC) PET for Evaluating Drug Delivery of Solid Tumors in Breast, Lung, Renal, and Adrenal Cancers

* 10-C-0077:

* 10-C-0071:
Phase 2, Open-Label Arm Study of the Efficacy and Safety of PF-02341066 in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC) Harboring a Translocation or Inversion Involving the Anaplastic Lymphoma Kinase (ALK) Gene Locus

* 10-C-0067:
A Phase 1-2 Study of CAT-8015 in Adult Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia

* 10-C-0066:
Collection of Human Samples to Study Hairy Cell and Other Leukemias and to Develop Recombinant Immunotoxins for Cancer Treatment

* 10-C-0062:
A Phase I/II Study of TRC105 in Metastatic Castrate Resistant Prostate Cancer (CRPC)

* 10-C-0050:
A Randomized Phase II Study of Rituximab with ABVD Versus Standard ABVD for Subjects with Advanced-Stage Classical Hodgkin Lymphoma with Poor Risk Features (IPS score >2)

* 10-C-0025:
Randomized Phase II Trial of Rituximab with Either Pentostatin or Bendamustine for Multiply Relapsed or Refractory Hairy Cell Leukemia

* 10-C-0021:
A Phase I Study of Intravenous Recombinant Human IL-15(rhIL-15) in Adults with Metastatic Malignant Melanoma and Metastatic Renal Cell Cancer

* 10-C-0019:
Development and Validation of a Symptom Scale for Children with Chronic Graft-Versus-Host Disease

* 09-N-0160:
Convection Enhanced Delivery of Muscimol to Study the Pathophysiology Underlying the Clinical Features of Parkinson's Disease

* 09-M-0177:
CO2 Inhalation and Risk for Panic Disorder

* 09-I-0226:
A Pilot Study for Collection of Anti-Influenza A Immune Plasma

* 09-I-0170:
Immune Responses to Varicella-Zoster Virus Vaccination and Infection

* 09-I-0163:
HVTN 505: Ph 2 RPCT Test-of-Concept Trial to Eval Safety/Effect Post-HIV Acquisition Viremia of Multiclade HIV-1 DNA Plasmid Vaccine F/B Multiclade HIV-1 Recombinant Adenoviral Vector Vaccine in HIV-Uninfected, Adenovirus Type 5 Neutralizing AB Negative

* 09-I-0108:
Strategic Timing of AntiRetroviral Treatment (START)

* 09-HG-0009:
Participant Reactions to Disease Risk Information

* 09-H-0239:
Cellular and Molecular Characterization of the Immune Response in Healthy NIH Employees at Baseline, and After Immunization with the H1N1 or Seasonal Influenza Vaccines

* 09-H-0215:
Multi Center Combined Non-invasive Coronary Angiography and Myocardial Perfusion Imaging using 320-Detector Computed Tomography

* 09-H-0183:
Horse ATG/CsA in Aplastic Anemia Patients Unresponsive to or with a Suboptimal Response to Rabbit ATG/CsA Treatment

* 09-H-0166:
Evaluation of Outcomes Following Mitral Valve Repair/Replacement in Severe Chronic Ischemic Mitral Regurgitation

* 09-H-0164:
Comparison of Cardiac Computed Tomography and Vasodilator Stress Magnetic Resonance Imaging Perfusion in Patients with Prior Equivocal Stress Test for Detection of Coronary Artery Disease

* 09-H-0154:
A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R Agonist), Eltrombopag, in Aplastic Anemia Patients with Immunosuppressive-Therapy Refractory Thrombocytopenia

* 09-H-0087:
Mismatched Donor Lymphocyte Infusions for Relapsed Disease Following Allogeneic Stem Cell Transplantation

* 09-H-0050:
Surgical Interventions for Moderate Ischemic Mitral Regurgitation

* 09-DK-0081:
Selective Reduction of Dietary Carbohydrate Versus Fat: Effects on Metabolism, Endocrine Physiology, Brain Activity and Reward Circuitry

* 09-DK-0055:
Assessment of the Effects of a DPP-4 Inhibitor (Sitagliptin) Januvia on Immune Function in Healthy Individuals

* 09-CH-0203:
Cholesterol in Autism Spectrum Disorder (ASD): Characterization and Treatment

* 09-CH-0180:
Non-Invasive Non-Ionizing Polarized Imaging System to Assess Structure of Cervix

* 09-CC-0227:
Phenomenological Study of Psycho-Socio-Spiritual Healing in the Context of Chronic or Life-Threatening Illness

* 09-CC-0217:
Vasti Control of Patellofemoral Kinematics in Asymptomatic Volunteers

* 09-C-0235:
A Phase 2, Open Label Trial of Dacomitinib (PF-00299804) in Selected Patients with Advanced Adenocarcinoma of the Lung

* 09-C-0224:
Pilot Study of Radiation-Enhanced Allogeneic Cell Therapy for Progressive Hematologic Malignancy After Allogeneic Hematopoietic Stem Cell Transplantation

* 09-C-0222:
A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination with Carboplatin versus Carboplatin Alone Followed by Vandetanib Alone in Adults with Recurrent High-Grade Gliomas

* 09-C-0212:
Multicenter Phase II Study of IMC-A12 in Patients with Thymoma and Thymic Carcinoma who have been Previously Treated with Chemotherapy

* 09-C-0195:
A Phase 2 Trial of Bevacizumab, Lenalidomide, Docetaxel, and Prednisone (ART-P) for Treatment of Metastatic Castrate-Resistant Prostate Cancer

* 09-C-0189:
Prospective Randomized Trial Comparing Gastrectomy, Metastasectomy Plus Systemic Therapy Versus Systemic Therapy Alone: GYMSSA Trial

* 09-C-0139:
A Pilot Study of Vaccination with Epitope-Enhanced TARP Peptide and TARP Peptide-Pulsed Dendritic Cells in the Treatment of Stage D0 Prostate Cancer

* 09-C-0104:
A Randomized, Double-Blinded, Placebo-Controlled, Multi-Institutional, Cross-Over, Phase II.5 Study of Saracatinib (AZD0530), a Selective Src Kinase Inhibitor, In Patients with Recurrent Osteosarcoma Localized to the Lung

* 09-C-0103:
Prospective Analysis of Genotypes in Adults Undergoing Therapy for Lung Cancer

* 09-C-0096:
Pilot and Feasibility Study of Reduced-Intensity Hematopoietic Stem Cell Transplant for Patients with GATA2 Mutations

* 09-C-0089:
A Targeted Ph I/II Trial of ZD6474 (Vandetanib; ZACTIMA) Plus the Proteasome Inhibitor, Bortezomib (Velcade ), in Adults with Solid Tumors with a Focus on Hereditary or Sporadic, Locally Advanced or Metastatic Medullary Thyroid Ca (MTC)

* 09-C-0080:
A Phase 2, Open-label, Proof-of-Concept Study to Assess the Ability to Detect Tumours and Angiogenesis via the Expression of Alpha v Beta 3 Integrin Receptors by (18F)AH-111585 PET Imaging

* 09-C-0072:
Randomized Pilot Study for the Treatment of Cutaneous Leiomyomas with Botulinum Toxin

* 09-C-0065:
Phase 1 Trial of Siplizumab and Dose-Adjusted EPOCH-Rituximab (DA-EPOCH-R) in T and NK-Cell Lymphomas

* 09-C-0054:
A Group Wide Biology and Banking Study for Phase II Study of R1507

* 09-C-0037:
A Phase II Clinical Trial of Ixabepilone (Ixempra [R], BMS-247550, NSC 710428), an Epothilone B Analog, in Cervical Cancer

* 09-C-0025:
Phase II Trial of LMB-2, Fludarabine and Cyclophosphamide for Adult T-Cell Leukemia

* 09-C-0024:
A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents and Young Adults

* 09-C-0005:
Randomized Trial of Cladribine (CdA) with Simultaneous or Delayed Rituximab to Eliminate Hairy Cell Leukemia Minimal Residual Disease

* 09-AR-0006:
A Multi-Center, Open Label, 24-Month Treatment Study to Establish the Safety, Tolerability, Efficacy, Pharmacokinetics and Pharmacodynamics of Canakinumab (anti-IL-1 Beta Antibody) in Patients with NOMID / CINCA Syndrome

* 08-N-0044:
A Prospective Natural History Study of Patients with Neurofibromatosis Type 2 (NF2)

* 08-HG-0122:
Patient-Provider Communication and Interaction in a Virtual Clinical Setting

* 08-H-0177:
Multicenter International Lymphangioleiomyomatosis Efficacy of Sirolimus Trial (The MILES Trial)

* 08-H-0108:
Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprotein in Overweight or Obese Women

* 08-H-0084:
Evaluation of Systemic Toxicity Associated with Allogeneic Peripheral Blood Stem Cell Infusion

* 08-H-0016:
Effect of Fasting on the Size of Lymphangioleiomyomas in Patients with Lymphangioleiomyomatosis

* 08-DK-0165:
Thyroid Hormones Homeostasis and Energy Metabolism Changes During Stimulation of Endogenously Secreted Bile Acids (BAs)

* 08-DK-0149:
High Dose Ribavirin in Combination with Peginterferon for Patients with Chronic Hepatitis C Genotype 1 Infection Who Have Failed to Respond or Relapsed after Standard Therapy

* 08-DK-0106:
Hepatitis C Eradication and Progression of Atherosclerosis

* 08-CH-0139:
Preventing Excessive Weight Gain in Adolescent Girls at High-Risk for Adult Obesity

* 08-CH-0085:
Eating Behavior in Adolescents

* 08-CC-0220:
A Phase II Clinical Trial to Determine the Effectiveness of Problem Solving Education in Caregivers and Patients during Allogeneic HSCT

* 08-CC-0032:
Parental Permission and Adolescent Assent and Decision Making in Clinical Research

* 08-C-0151:
A Pilot Study of Sirolimus (Rapamycin, Rapammune[Registered Trademark]) in Subjects with Cowden Syndrome or Other Syndromes Characterized by Germline Mutations in PTEN

* 08-C-0148:
A Pilot Study of Imatinib Mesylate in Children and Adults with Sclerotic Skin Changes of Chronic Graft-Versus-Host Disease

* 08-C-0123:
A Phase 1, Multi-Center, Dose Escalation Study of CAT-8015 in Children, Adolescents, and Young Adults with Refractory CD22+ Acute Lymphoblastic Leukemia (ALL) or Non-Hodgkin s Lymphoma (NHL)

* 08-C-0121:
Phase II Study of Metastatic Cancer that Expresses NY-ESO-1 Using Lymphodepleting Conditioning Followed by Infusion of Anti-NY ESO-1 TCR-Gene Engineered Lymphocytes

* 08-C-0101:
A Phase 2 Trial of Tandutinib in Combination with Bevacizumab for Patients with Recurrent High-Grade Gliomas

* 08-C-0097:
Multi-Institutional Prospective Phase II Study of Montelukast for the Treatment of Bronchiolitis Obliterans Following Allogeneic or Autologous Stem Cell Transplantation in Children and Adults

* 08-C-0096:
A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromatosis Type 1 Related Plexiform Neurofibromas

* 08-C-0092:
A Phase I Study with an Expansion Cohort of the PARP Inhibitor AZD2281 Combined with Carboplatin in BRCA1/2 Familial Breast and Ovarian Cancer and Sporadic Triple Negative Breast and Ovarian Cancer

* 08-C-0078:
A Phase II Trial of Pemetrexed (Alimta [Registered Trademark]) Combined with Sirolimus (Rapamycin, Rapamune [Registered Trademark]) in Subjects with Relapsed or Refractory NSCLC

* 08-C-0051:
A Pilot Trial of WT1 Peptide-Loaded Allogeneic Dendritic Cell Vaccine and Donor Lymphocyte Infusion for WT1-Expressing Hematologic Malignancies

* 08-C-0026:
A Phase 1, Single Center, Dose-Escalation Study of SS1(dsFv)PE38 Administered Concurrently with Pemetrexed and Cisplatin in Subjects with Unresectable Malignant Epithelial Pleural Mesothelioma

* 08-C-0020:
A Phase 2 Study of ZD6474 (Vandetanib) in Patients with Von Hippel Lindau Disease and Renal Tumors

* 08-C-0015:
A Phase II Trial of Enzastaurin (LY317615) in Combination with Bevacizumab in Adults with Recurrent Malignant Gliomas

* 08-C-0007:
A Phase I Study of Ipilimumab (Anti-CTLA-4) in Children, Adolescents, and Young Adults with Treatment Refractory Cancer

* 08-AR-0008:
Insulin Resistance and Atherosclerosis in a Sample of Women with Systemic Lupus Erythematosus

* 08-AA-0137:
A Randomized, Double-blind, Placebo Controlled Trial (RCT) of Varenicline to Reduce Alcohol Consumption in Heavy Drinkers

* 07-H-0225:
A Pilot Study of the Safety and Activity of Escalating Doses of ON 01910.Na in Patients with RAEB-1 AND RAEB-2 Myelodysplastic Syndrome (MDS) and AML with Trisomy 8

* 07-H-0196:
Niacin Therapy to Improve Endothelial Function in Sickle Cell Disease

* 07-H-0181:
Pulmonary Hypertension and the Hypoxic Response in SCD

* 07-H-0177:
Treatment of Pulmonary Hypertension and Sickle Cell Disease with Sildenafil Therapy

* 07-H-0159:
Efficacy of WT1 and PRI Peptide Vaccination for Patients with Low Risk Myeloid Malignancies

* 07-H-0136:
Selective Depletion of Alloreacting T Cells Using a Photodepletion Technique to Prevent GVHD after HLA-Matched Peripheral Blood Stem Cell Transplantation for Subjects with Hematologic Malignancies

* 07-H-0104:
A Phase II Study of Lenalidomide Revlimid in Previously Treated Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

* 07-EI-0213:
Laboratory of Immunology/National Eye Institute Repository

* 07-E-0012:
Rituximab in the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)

* 07-DK-0219:
A Nutrigenomics Intervention for the Study of the Role of Dietary Sitosterol on Lipid, Glucose and Energy Metabolism

* 07-DK-0163:
The Effect of Diet on Vascular Disease: A Study of African American and Caucasian Women

* 07-CH-0126:
Pilot Study of the Metabolic Effects of Betahistine Hydrochloride in Overweight Women

* 07-CH-0008:
Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion

* 07-CC-0153:
Effects of Peripheral Blood Stem Cell Transplantation on the Microbial Flora of the Oral Cavity

* 07-CC-0011:
Hypnosis as a Pain and Symptom Management Strategy in Patients with Sickle Cell Disease

* 07-C-0206:
A Pilot Study of Tumor Vaccination and R-hIL-7 Following Standard Multimodality Therapy in Patients with High Risk Pediatric Solid Tumors

* 07-C-0189:
Phase I/II Trial of Vandetanib (ZD6474, ZACTIMA) in Children and Adolescents with Hereditary Medullary Thyroid Carcinoma

* 07-C-0130:
A Phase 1, Multicenter, Dose-Escalation Study of CAT-8015 in Patients with Relapsed or Refractory Hairy Cell Leukemia (HCL)

* 07-C-0121:
A Phase 2 Study of the C-Met RTK Inhibitor Foretinib (Formerly GSK 1363089) in Subjects with Papillary Renal-Cell Carcinoma (PRC)

* 07-C-0111:
A Pilot Study of Markers of Tumor Burden and Radiation Toxicity in the Blood, Urine, and Stool of Patients Receiving Radiotherapy for Gastrointestinal Malignancies

* 07-C-0107:
A Randomized Phase II Trial Combining Vaccine Therapy with PROSTVAC/TRICOM and Flutamide vs. Flutamide Alone in Men with Androgen Insensitive, Non-Metastatic (D0.5) Prostate Cancer

* 07-C-0101:
A Phase 0 Trial of (111)Indium CHX-A DTPA Trastuzumab Imaging in Cancer

* 07-C-0081:
A Phase I/II Study of Flavopiridol in Relapsed or Refractory Mantle Cell Lymphoma (MCL) and Diffuse Large B-Cell Lymphoma (DLBCL)

* 07-C-0058:
A Phase II Study of Sorafenib and Bevacizumab in Epithelial Ovarian, Fallopian, and Peritoneal Cancer

* 07-C-0053:
A Phase I Trial of Enzastaurin (LY317615) in Combination with Carboplatin in Adults with Recurrent Gliomas

* 07-C-0047:
A Phase I Trial of Nelfinavir (Viracept) in Adults with Solid Tumors

* 07-C-0040:
A Phase I Trial of Monoclonal Antibody HGS-ETR2 (Lexatumumab) with or without Interferon Gamma in Patients with Refractory Pediatric Solid Tumors

* 07-C-0006:
A Phase 1/2a Study Evaluating the Safety, Pharmacokinetics and Efficacy of ABT-263 in Subjects with Relapsed or Refractory Lymphoid Malignancies

* 06-N-0174:
Cortical Function in Primary Lateral Sclerosis and Amyotrophic Lateral Sclerosis

* 06-N-0113:
Phase II Clinical Trial to Examine the Efficacy and Safety of Dutasteride in Patients with Kennedy's Disease (Spinal and Bulbar Muscular Atrophy)

* 06-M-0102:
Clinical and Immunological Investigations of Subtypes of Autism

* 06-I-0235:
A Phase II Vaccine Dose Finding Pilot Study for Development of an Anti-Influenza A (H5N1) Intravenous Hyper-Immune Globulin

* 06-I-0217:
Genetic Disorders of Mucociliary Clearance

* 06-I-0197:
A Randomized Placebo Controlled Trial of Atorvastatin in HIV Positive Patients Not on Antiretroviral Medications with the Specific Aims of Studying the Effects of Atorvastatin on HIV Viral Load and Immune Activation Markers

* 06-I-0086:
A Cohort Observational Study Evaluating Predictors, Incidence and Immunopathogenesis of Immune Reconstitution Syndrome (IRIS) in HIV-1 Infected Patients with CD4 Count Less Than or Equal to 100 Cells/microL Who Are Initiating Antiretroviral Therapy

* 06-I-0030:
Correlation of the Precursor Frequency of CD4 + Effector Memory T Cells with Induration Measured in the Tuberculin Skin Test (TST)

* 06-HG-0134:
Natural History and Biology of Dermal Neurofibromas in Neurofibromatosis Type 1

* 06-H-0248:
Peripheral Blood Stem Cell Allotransplantation for Hematological Malignancies Using a Positive Stem Cell Selection Technique for T Cell Depletion, Followed by Delayed T Cell Add-Back

* 06-H-0208:
Cardiovascular Magnetic Resonance Imaging of Pediatric Healthy Volunteers

* 06-H-0202:
Cardiopulmonary Function Assessment and NO Based Therapies for Patients with Hemolysis-Associated Pulmonary Hypertension

* 06-H-0156:
A Pilot Study of the Safety and Activity of Escalating Doses of AMD3100 to Mobilize CD34+ Cells in Healthy Volunteers

* 06-H-0082:
Telomere Repair Gene Mutations in Inflammatory Bowel Disease

* 06-H-0054:
Evaluation of Synergy of Combining Hydroxyurea with Recombinant Human Erythropoietin Glycoform Alpha (rhu Erythropoietin-alpha) on Fetal Hemoglobin Synthesis in Patients with Sickle Cell Anemia

* 06-H-0034:
A Randomized Study of Three Immunosuppressive Regimens in Treatment Naive Patients with Severe Aplastic Anemia: Horse ATG/CsA Taper vs Rabbit-ATG/CsA vs Alemtuzumab

* 06-EI-0050:
Multicenter Uveitis Steroid Treatment (MUST) Trial Protocol

* 06-DK-0183:
Gene Expression and Release of Inflammatory Mediators in Overweight Subjects Before and After Weight Loss

* 06-DK-0025:
The Effects of Lithium Carbonate on Low Dose Radioiodine Ablation in Early Thyroid Cancer Treatment

* 06-DK-0020:
Kidney Disease Biomarkers

* 06-DC-0218:
Neural Modeling and Brain Imaging of Tinnitus

* 06-D-0206:
Open-Label, Dose-Escalation Study Evaluating the Safety of a Single Administration of AdhAQP1, an Adenoviral Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in Individuals with Irradiation-Induced Parotid Salivary Hypofunction

* 06-CH-0223:
Biobehavioral Study of Recently Adopted Children

* 06-CH-0090:
Evaluation of Whether the Selective Progesterone Receptor Modulator CDB-2914 Can Shrink Leiomyomata

* 06-CH-0038:
Body Heat Content and Dissipation in Obese and Normal Weight Adults

* 06-C-0233:
A Phase I/II Study of the RAF Kinase and Receptor Tyrosine Kinase Inhibitor Sorafenib (BAY 43-9006, NSC# 724772 IND# 69896) in Children with Refractory Solid Tumors or Refractory Leukemias

* 06-C-0227:
Phase I Trial of Intravenous Fenretinide (4-HPR) for Patients with Hematologic Malignancies

* 06-C-0221:
A Phase I Trial of 5-Fluoro-2'-Deoxycytidine with Tetrahydrouridine in Advanced Malignancies

* 06-C-0198:
A Pilot Pediatric/Adult Study of Gene Expression Profiling and Clinical Characterization of Phototoxicity

* 06-C-0150:
A Phase II Clinical Trial of Anti-Tac(Fv)-PE38 (LMB-2) Immunotoxin for CD25 Positive Hairy Cell Leukemia

* 06-C-0112:
A Phase II Clinical Trial of the Histone Deacetylase Inhibitor Valproic Acid in Combination with Temodar and Radiation Therapy in Patients with High Grade Gliomas: Multi-Institutional Trial

* 06-C-0088:
A Random-Assignment Study of Hepatic Arterial Infusion of Melphalan with Venous Filtration via Peripheral Hepatic Perfusion (PHP) (Delcath System) Versus Best Alternative Care for Ocular and Cutaneous Melanoma Metastatic to the Liver

* 06-C-0083:
Phase I and Pharmacokinetic Study of BAY 43-9006 (Sorafenib) in Patients with Kaposi's Sarcoma

* 06-C-0043:
Phase II Trial of Chemotherapy in Sporadic and Neurofibromatosis Type 1 Associated High Grade Malignant Peripheral Nerve Sheath Tumors

* 05-N-0245:
A Six Month Double-Blind, Placebo-Controlled Phase 2 Clinical Trial to Determine the Safety and Efficacy of Idebenone Administered to Patients with Friedreich's Ataxia

* 05-N-0228:
The Role of Cortical Coherence in Focal Hand Dystonia

* 05-N-0189:
Neuropathological Basis of Spasmodic Dysphonia and Related Voice Disorders

* 05-M-0059:
5HT1A and SERT Imaging During Pharmacologically Induced Hypogonadotropic Hypogonadism With and Without Estrogen and Progesterone Replacement

* 05-HG-0236:
Pilot Study of the Use of Intravenous Immune Globulin in Hereditary Inclusion Body Myopathy

* 05-HG-0152:
Variation in Gene Expression in Neurofibromatosis Type 1

* 05-HG-0076:
Long-Term Clinical Trial of Nitisinone in Alkaptonuria

* 05-HG-0004:
Clinical Investigations into Hutchison-Gilford Progeria Syndrome

* 05-H-0019:
A Prospective, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study of Nitric Oxide for Inhalation in the Acute Treatment of Sickle Cell Pain Crisis

* 05-H-0016:
Therapeutic Application of Intravascular Nitrite for Sickle Cell Disease

* 05-DK-0119:
Peripheral Thyroid Hormone Conversion and Glucose and Energy Metabolism

* 05-DC-0238:
Effects of Sleep Deprivation and Recovery Sleep on Speech, Language and Other Higher Cognitive Functions: A Combined EEG-fMRI Study

* 05-CH-0037:
The Effects of Hydrocortisone, Melatonin, and Placebo on Symptoms of Jet Lag

* 05-CH-0013:
Adrenal Function in Critical Illness

* 05-CC-0216:
Prospective Assessment of Functional Status, Psychosocial Adjustment, Health Related Quality of Life and the Symptom Experience in Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation

* 05-CC-0093:
The Effect of Animal-Assisted Therapy on Distress in Oncology Patients Being Treated for Pain

* 05-CC-0041:
Endothelial Cell Dysfunction in Pulmonary Arterial Hypertension: Biomarkers, Mechanisms of Disease and Novel Therapeutic Targets

* 05-CC-0012:
Effects of Inhaled Carbon Monoxide on Pulmonary Inflammatory Responses Following Endotoxin Instillation

* 05-CC-0008:
Revising Employee Benefits for the Sake of Health

* 05-C-0252:
Phase III Randomized Study of R-CHOP v. Dose-Adjusted EPOCH-R with Molecular Profiling in Untreated de Novo Diffuse Large B-Cell Lymphomas

* 05-C-0241:
A Pilot Study of Image Guided Prostate and Pelvic Nodal Irradiation with Intensity Modulated Radiation Therapy (IMRT) in Prostate Cancer

* 05-C-0229:
A Randomized Pilot Phase II Study of Docetaxel Alone or in Combination with PANVAC(Trademark)-V (Vaccinia) and PANVAC(Trademark)-F (Fowlpox) in Adults with Metastatic Breast Cancer

* 05-C-0191:
A Phase I Study of Image Guided Dose Escalation with Intensity Modulated Radiation Therapy (IMRT) to Histologically Confirmed Regions of Prostate Cancer

* 05-C-0185:
Phase II Study of the Efficacy and Toxicity of Ontak (Denileukin Diftitox) in the Therapy of Adult T-Cell Leukemia

* 05-C-0137:
A Phase II Trial of Tamoxifen and Bortezomib in Patients with Recurrent High-Grade Gliomas

* 04-N-0071:
Phase I/II Study of HTLV-I-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) Using the Humanized MiK-Beta-1 Monoclonal Antibody Directed Toward the IL-2/IL-15R-Beta Subunit (CD122) that Blocks IL-15 Action

* 04-M-0183:
Association between Adenosine Receptor Gene Polymorphisms and Physiological Responses to Caffeine in Subjects with Panic Disorder and Healthy Controls

* 04-M-0139:
The Effects of Dutasteride on Mood, HPA Axis, and Serum Allopregnanolone Levels in Women with Menstrual-Related Mood Disorders and Controls

* 04-HG-0123:
Bardet-Biedl Syndrome: Phenotype and Metabolic Characteristics

* 04-H-0213:
Cytokine Gene Polymorphisms in Bone Marrow Failure

* 04-H-0179:
Peripheral Blood Hematopoietic Progenitor Cell Mobilization Using Granulocyte Colony Stimulating Factor (G-CSF) Combined with AMD3100 in Healthy Volunteers

* 04-H-0112:
Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation Followed by T Cell Add-Back for Hematological Malignancies - Effect of Peritransplant Cyclosporine on Chimerism

* 04-H-0078:
Peripheral Blood Hematopoietic Progenitor Cell Mobilization with AMD 3100 (Mozobil) in Healthy Volunteers Previously Mobilized with G-CSF

* 04-CH-0056:
The Neural Immune Mechanisms and Genetic Influences on Chronic Pelvic Pain in Women with Endometriosis

* 04-CH-0050:
Eating Behavior in Children

* 04-CC-0178:
The Treatment of Deep Vein Thrombosis of the Lower Extremities with "Low-Dose" Alteplase: a Pilot Study

* 04-CC-0070:
Exploring Patient-Provider Trust among Individuals with End-Stage Renal Disease

* 04-CC-0046:
Citrate Effects and Bone Density Studies in Long-Term Apheresis Donors

* 04-CC-0032:
Atorvastatin Therapy To Improve Endothelial Function in Sickle Cell Disease

* 04-C-0273:
A Phase II Study of Hepatic Arterial Infusion of Melphalan with Venous Filtration via Peripheral Hepatic Perfusion (PHP) for Unresectable Primary and Metastatic Cancers of the Liver

* 04-C-0257:
A Phase II Trial of Docetaxel, Thalidomide, Prednisone and Bevacizumab in Patients with Androgen-Independent Prostate Cancer

* 04-C-0246:
An Open Label Pilot Study to Evaluate the Safety and Tolerability of PANVAC-V (Vaccinia) and PANVAC-F (Fowlpox) in Combination with Sargramostim in Adults with Metastatic Carcinoma

* 04-C-0238:
A Phase II Study of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Von Hippel Lindau Disease and Renal Tumors

* 04-C-0232:
A Multi-Institutional Study of Proteomic Evaluation of Epithelial Ovarian Cancer, Primary Peritoneal Cancer, and Fallopian Tube Cancer Patients in First Clinical Remission: Development of a Protein Fingerprint Profile of Relapse

* 04-C-0177:
A Pilot Study of Tc-94m Sestamibi PET MDR Imaging

* 04-C-0173:

* 04-C-0171:
A Prospective Histopathologic Study of Dynamic Contrast Enhanced MRI for Prostate Cancer Delineation and Characterization with the APT-MRI System

* 04-C-0155:
Barrett's Esophagus Early Detection Study

* 04-C-0089:
Phase I Open-Label Single-Dose Study of Humanized Mik-Beta-1 Monoclonal Antibody Directed Toward the IL-2R/IL-15R-Beta Subunit (CD122) in T Cell Large Granular Lymphocytic Leukemia

* 04-C-0080:
Phase II Trial of Pirfenidone in Children, Adolescents, and Young Adults with Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas

* 04-C-0049:
A Phase I/II Study of an Antitumor Vaccination Using Alpha (1,3) Galactosyltransferase Expressing Allogeneic Tumor Cells in Patients with Refractory or Recurrent Non-Small Cell Lung Cancer

* 04-C-0044:

* 04-C-0031:
Phase I Trial of Medi-507 in CD2-Positive Lymphoproliferative Disease

* 03-N-0293:
Induction of Mucosal Tolerance to Human E-Selectin for the Secondary Prevention of Stroke

* 03-N-0203:
SMN Levels in Peripheral Blood Samples of SMA Patients and the Effects of Pharmacological Compounds In Vitro

* 03-M-0175:
The Effects of Acute Withdrawal of Estradiol on Mood Symptoms in Women with Perimenopausal Depression

* 03-M-0014:
Neural Circuitry and Risk for Depression in Adolescents: A Study Using Functional Magnetic Resonance Imaging

* 03-I-0090:
Immune Responses to Vaccinia Virus Vaccination

* 03-HG-0313:
Genetic Analysis of Gray Platelet Syndrome

* 03-H-0282:
Characterization of Cardiac Function in Subjects with Hereditary Hemochromatosis Who Are New York Heart Association Functional Class I

* 03-H-0249:
A Randomized Trial of Immunosupression in Aplastic Anemia Patients with Refractory Pancytopenia or Suboptimal Hematologic Response after h-ATG/CsA Treatment

* 03-H-0201:
Cytokine Gene Polymorphisms in Allotransplant Donors

* 03-H-0193:
A Randomized Trial of a Novel Immunosuppressive Combination of ATG, CsA and Sirolimus (Rapamune) vs a Slow Taper Cyclosporine Regimen in Subjects with Severe Aplastic Anemia

* 03-H-0192:
Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation Followed by T Cell Add-Back for Hematological Malignancies Effect of Irradiated Donor Lymphocytes on Chimerism

* 03-H-0051:
Collection of Blood, Stool, Bone Marrow and/or Tissue Samples from Subjects with Hepatitis-Associated Aplastic Anemia

* 03-DK-0245:
Effect of AC 2993 (Synthetic Exendin-4) - Administered Alone or in Combination with Daclizumab - on Islet Function in Patients with Type I Diabetes

* 03-DK-0226:
Pulse Dexamethasone Over 48 Weeks for Podocyte Disease

* 03-DK-0071:
Sirolimus Therapy in Idiopathic and Lupus Membranous Nephropathy

* 03-CH-0225:
Investigation of Simvastatin Therapy in Smith-Lemli-Opitz Syndrome

* 03-CH-0069:
Early Learning and Development Project

* 03-CC-0301:
Health Beliefs and Health Behavior Practices among Minorities with Rheumatic Diseases

* 03-CC-0127:
Evaluation of Potential Synergy of Combining Hydroxyurea with Nitric Oxide Donors on Fetal Hemoglobin Synthesis in Patients with Sickle Cell Anemia

* 03-C-0304:
Phase 2 Trial of Alemtuzumab and Dose-Adjusted Epoch in Chemotherapy Naive Aggressive T and NK-Cell Lymphomas

* 03-C-0194:
Phase II Study of the Efficacy and Toxicity of Campath-1H in the Therapy of Adult T-Cell Leukemia

* 03-C-0190:
Trans-Rectal Placement of Prostatic Fiducial Markers under MR-Guidance in Patients Receiving External Beam Radiotherapy for Prostate Cancer: A Pilot Study

* 03-AR-0298:
A Long-Term Outcome Study with the IL-1 Receptor Antagonist anakinra/Kineret in Patients with Neonatal Onset Multisystem Inflammatory Disease (NOMID/CINCA Syndrome) A Therapeutic Approach to Study the Pathogenesis of this Disease

* 03-AR-0133:
Clinically Important Changes in Rheumatoid Arthritis

* 03-AR-0130:
Genetic Determinants of Ankylosing Spondylitis Severity - Cross Sectional Study

* 02-NR-0169:
Complex Regional Pain Syndrome Proteomics Study

* 02-N-0128:
Evaluation of Tourette's Syndrome with Multimetabolite H-Magnetic Resonance Spectroscopy at 3T

* 02-M-0092:
Reward-Related Processes and Brain Function

* 02-M-0036:
A Behavioral and Functional Neuroimaging Study of Inhibitory Motor Control

* 02-H-0265:
Identification of Genes Expressed in Atherosclerotic Plaques

* 02-H-0111:
Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation Followed by T Cell Add-Back for Hematological Malignancies - Role of Preparative Regimen and T Cell Dose in Graft Rejection and GVHD

* 02-DK-0022:
Long-Term Efficacy of Leptin Replacement in Treatment of Lipodystrophy

* 02-CH-0309:
The Diagnostic Performance of Screening Tests for the Diagnosis of Cushing's Syndrome

* 02-CH-0287:
Treatment of Leiomyomata with the Selective Progesterone Receptor Modulator CDB-2914

* 02-CH-0278:
Dyadic Interactions in Depressed and Non-Depressed Mothers and Their Infants

* 02-CH-0100:
Supplemental Calcium in Overweight Out-Patients

* 02-CC-0247:
Values at the Bedside: A Survey of European Physicians Regarding Ethical Dilemmas in Clinical Practice

* 02-CC-0044:
Morbidity Following the Diagnosis and Treatment of Patients With Breast Cancer: A Multi-Institutional Study between the National Institutes of Health (NIH) Rehabilitation Medicine Department (RMD) and the Walter Reed National Military Medical Center (WRN

* 02-C-0268:
Prospective Study of Prophylactic Salpingo-Oophorectomy and Longitudinal CA-125 Screening Among Women at Increased Genetic Risk of Ovarian Cancer

* 02-C-0259:
Pilot Study of Allogeneic/Syngeneic Blood Stem Cell Transplantation in Patients with High-Risk and Recurrent Pediatric Sarcomas

* 02-C-0215:
Amifostine as a Rectal Protector during External Beam Radiotherapy for Prostate Cancer: A Phase II Study

* 02-C-0207:
A Phase II Study of MR-Guided High Dose Rate Brachytherapy Boosts For Prostate Cancer

* 02-C-0205:
Phase I Study of Gene Induction Mediated by Sequential Decitabine/Depsipeptide Infusion with or without Concurrent Celecoxib in Subjects with Pulmonary and Pleural Malignancies

* 02-C-0193:
A Phase II Study of Pegylated Interferon Alfa-2b (Peg-Intron (TM)) in Children with Diffuse Pontine Gliomas

* 02-C-0144:
Establishment of Normal High Risk Breast Epithelial Cell Cultures, and A High Risk Cell Line and Tissue Repository from Breast Tissue from Women at High Risk of Breast Cancer

* 02-C-0140:
A Prospective National Study to Molecularly and Genetically Characterize Human Gliomas: The Glioma Molecular Diagnostic Initiative

* 02-AR-0272:
A Phase I, Open-Labeled, Dose-Ascending Clinical Trial of Immunotherapy of MRA, A Humanized Anti-IL 6 Receptor Monoclonal Antibody, In Patients with Systemic Lupus Erythematosus

* 02-AR-0156:

* 01-M-0152:
Adolescence, Puberty, Hormones, and Emotion Regulation: An fMRI Study

* 01-H-0223:
Inhaled Nitric Oxide and Transfusion Therapy for Patients with Sickle Cell Anemia and Secondary Pulmonary Hypertension

* 01-H-0162:
Ex Vivo Selective Depletion of Alloreactive Donor T-Lymphocytes Using RFT5-SMPT-dgA, a Specific Anti-Interleukin-2 Receptor Immunotoxin: Reducing GVHD Risk Associated with HLA-Matched, Nonmyeloablative, Peripheral Blood Stem Cell Transplantation for Hema

* 01-DK-0249:
Ingested Interferon-Alpha: Prolongation or Permanence of the "Honeymoon" Phase in Newly Diagnosed Diabetes Mellitus

* 01-DK-0247:
Treatment of Chronic Delta Hepatitis with Pegylated Interferon

* 01-DK-0246:
Combination of Lamivudine and Adefovir Dipivoxil for Treatment of Chronic Hepatitis B

* 01-DK-0053:
Permeability Factor in Focal Segmental Glomerulosclerosis

* 01-DK-0036:
Solitary Islet Transplantation for Type 1 Diabetes Mellitus Using Steroid Sparing Immunosuppression

* 01-DC-0230:
Studies of Deficits in the Sense of Taste

* 01-CH-0086:
A Combination Therapy with Cystagon and N-Acetylcysteine for INCL Patients

* 01-C-0235:
Combination Antibody Therapy with Apolizumab (1D10) and Rituximab (CD20) in Relapsed Lymphoma and CLL

* 01-C-0125:
Pilot Study of Non-Myeloablative, HLA-Matched Allogeneic Stem Cell Transplantation for Pediatric Hematopoietic Malignancies

* 01-C-0091:
Phase I Trial and Pharmacokinetic Study of Tariquidar (XR9576), a P-Glycoprotein Inhibitor, in Combination with Doxorubicin, Vinorelbine or Docetaxel in Pediatric Patients with Refractory Solid Tumors Including Brain Tumors

* 01-C-0049:
Phase II Trial of Depsipeptide in Patients with Cutaneous T-Cell Lymphoma and Relapsed Peripheral T-Cell Lymphoma

* 01-C-0027:
Natural History of Plexiform in Neurofibromatosis Type I

* 01-C-0009:
Breast Imaging Screening Studies in Women at High Genetic Risk of Breast Cancer: Annual Follow-up Study

* 01-C-0008:
Breast Imaging Studies in Women at High Genetic Risk of Breast Cancer: Menstrual Cycle Pilot Study

* 00-N-0140:
A Prospective Natural History Study of VHL Patients with CNS Hemangioblastomas

* 00-N-0057:
Positron Emission Tomography Imaging of Activation-Induced Signal Transduction in Human Brain

* 00-M-0103:
The Treatment of Menstrually-Related Mood Disorders with Continuous Gonadal Steroid Replacement

* 00-H-0169:
A Phase II Study of Antithymocyte Globulin (ATG) and Cyclosporine to Treat the Cytopenia of Myelodysplastic Syndrome (MDS)

* 00-H-0032:
Treatment of Severe Aplastic Anemia with Combined Immunosuppression: Antithymocyte Globulin (ATG) and Cyclosporine A (CSA), and Mycophenolate Mofetil (MMF)

* 00-DK-0186:
The Hep C Antiviral Long-Term Tx Against Cirrhosis (HALT-C) Trial: A Randomized Controlled Trial to Evaluate the Safety & Efficacy of Long-Term Peginterferon Alpha2A for Tx of Chronic Hep C in Patients Who Failed to Respond to Previous Interferon Therap

* 00-DK-0042:
Pirfenidone in Focal Segmental Glomerulosclerosis:Phase II Study

* 00-CH-0136:
A Trial of Pamidronate in Children with Osteogenesis Imperfecta

* 00-CH-0134:
Effects of Metformin on Energy Intake, Energy Expenditure, and Body Weight in Overweight Children with Insulin Resistance

* 00-C-0133:
Pilot Study of Idiotype Vaccine and EPOCH-Rituximab Chemotherapy in Untreated Mantle Cell Lymphoma

* 00-C-0121:
A Phase I Investigation of IL-12/Pulse IL-2 in Adults with Advanced Solid Tumors

* 00-C-0092:
A Randomized Trial of Filgrastim-SD/01 vs. Filgrastim in Newly Diagnosed Children and Young Adults with Sarcoma Treated with Dose-Intensive Chemotherapy

* 00-C-0080:
A Double Blinded Randomized Crossover Phase III Study of Oral Thalidomide versus Placebo in Patients with Stage D0 Androgen Dependent Prostate Cancer Following Limited Hormonal Ablation

* 00-C-0030:
A Phase I/II Study of the Efficacy and Toxicity of Humanized Anti-Tac (Zenapax ) in the Therapy of Tac-Expressing Adult T-Cell Leukemia

* 00-C-0018:
A Pilot Study of Proteomic Evaluation of Epithelial Ovarian Cancer Patients in First Clinical Remission: Development of a Protein Fingerprint Profile Associated with Relapse

* 99-HG-0056:
Pulmonary Fibrosis Associated with Rheumatoid Arthritis: Definition of the Natural History of Disease

* 99-H-0064:
Exploratory Study of Non-Myeloablative Allogeneic Stem Cell Transplantation and Donor Lymphocyte Infusions for Metastatic Neoplasms Refractory to Standard Therapy

* 99-H-0046:
Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation Followed by T-Cell Add-Back for Hematological Malignancies - Role of Cyclosporine

* 99-D-0070:
Natural History of Salivary Gland Dysfunction and Sjogren's Syndrome

* 99-C-0143:
Pilot Study of Donor Th2 Cells for the Prevention of Graft-Versus-Host Disease in the Setting of Non-Myeloablative, HLA-Matched Allogeneic Peripheral Blood Stem Cell Transplantation

* 99-C-0088:
(1)H-Nuclear Magnetic Resonance Spectroscopic Imaging of the Brain in Patients who Receive Neurotoxic Therapy

* 99-C-0081:
Methods in Education for Breast Cancer Genetics

* 99-C-0053:
Von Hippel-Lindau (VHL) Disease Genetic Epidemiology Study

* 98-CH-0111:
Safety and Efficacy of Orlistat (Xenical, Hoffmann LaRoche) in African American and Caucasian Children and Adolescents with Obesity-Related Comorbid Conditions

* 97-M-0126:
Childhood Onset Psychotic Disorders: Characterization and Treatment with Atypical Neuroleptics

* 97-HG-0192:
Genetic Studies in the Amish and Mennonites

* 97-HG-0085:
Therapeutic Clinical Trial of Oral Pirfenidone for the Pulmonary Fibrosis of Hermansky-Pudlak Syndrome

* 97-H-0202:
Low Intensity Preparative Regimen Followed by HLA-Matched, Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematologic Malignancies in Older Adults

* 97-H-0196:
A Phase II Study of HLA-Matched Peripheral Blood Stem Cell Transplantation for Metastatic Renal Cell Carcinoma as Adoptive Allogeneic Immunotherapy

* 97-H-0130:
Collection of Blood and Bone Marrow from Healthy Volunteers and Patients for Research Purposes

* 97-H-0117:
A Randomized Trial of Antithymocyte Globulin and Cyclosporine versus Cyclophosphamide and Cyclosporine in the Treatment of Severe Aplastic Anemia

* 97-H-0099:
HLA-Matched Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation Followed by T Cell Add-Back for Hematological Malignancies

* 97-DC-0180:
Genetic Analysis of Human Hereditary Hearing Impairment

* 97-C-0178:
Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): DNA Microarray Gene Expression Analysis

* 97-C-0110:
Phase I/II Study of Tac-Expressing Malignancies Other than Adult T-Cell Leukemia (ATL) with Yttrium-90 Radiolabeled Humanized Anti-Tac and Calcium-DTPA

* 97-C-0093:
A Pilot Study of 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Pediatric Patients with Primary and Metastatic Brain Tumors

* 97-C-0052:
A Pilot Study of Autologous T-Cell Transplantation with Vaccine Driven Expansion of Anti-Tumor Effectors after Cytoreductive Therapy in Metastatic Pediatric Sarcomas

* 97-C-0040:
EPOCH Chemotherapy Plus Rituximab for Previously Treated Patients with AIDS-Associated Lymphoma

* 96-M-0124:
Genetics of Obsessive-Compulsive Disorder: A Collaborative Study

* 96-CH-0101:
Population Differences in the Insulin Sensitivity, Resting Energy Expenditure, and Body Composition of Overweight Children and Children of Overweight Parents

* 96-CH-0033:
An Open, Randomized, Long-Term Clinical Trial of Flutamide, Testolactone, and Reduced Hydrocortisone Dose vs. Conventional Treatment of Children with Congenital Adrenal Hyperplasia

* 95-HG-0165:
Outcomes of Education and Counseling for HNPCC / Lynch Syndrome Testing

* 95-HG-0158:
Genetic Analysis of Hereditary Prostate Cancer

* 95-H-0167:
Effect of Hypoxia and Smoking on Oxidation of Proteins and Nucleic Acids in Human Volunteers

* 95-CH-0110:
Endometrial Mediators of Gonadal Steroid Action

* 92-CH-0034:
Studies of Growth Deficiency and Growth Hormone Treatment in Children with Osteogenesis Imperfecta Types III and IV

* 92-CC-0141:
The Cardiopulmonary Effects of Endotoxin in Normal Human Volunteers

* 92-C-0094:
Continuing Treatment for Children and Adults in the Center for Cancer Research

* 91-M-0230:
Mechanisms of Individual Variation of Dextroamphetamine Effects in Normal Human Subjects

* 91-M-0124:
Structural and Functional Imaging of Neuropsychiatric Patients and Normal Volunteers with 1.5 Tesla MRI

* 91-CH-0127:
Ovarian Follicle Function in Patients with Premature Ovarian Failure

* 90-DK-0137:
Evaluation of the Gastrinoma in Patients with Zollinger-Ellison Syndrome

* 90-CH-0149:
Early Copper Histidine Therapy in Menkes Disease

* 88-I-0172:
A Phase III Study with Long-Term Follow-Up of Zidovudine Versus Zidovudine and Alpha-Interferon Versus Alpha-Interferon in Patients with Early HIV Infection

* 88-CH-0032:
Specificity of Mother-Infant Interaction: The Influence of Maternal Age, Employment Status, and Parenthood Status

* 86-H-0088:
Lymphocytapheresis of Patients with Pancytopenia

* 85-M-0115:
Biological Markers in Childhood Psychiatric Disorders

* 85-H-0105:
Cardiovascular Evaluation of Homozygous Familial Hypercholesterolemia

* 85-H-0087:
Clinical Course of Patients with Transfusional Hemochromatosis on Deferoxamine

* 84-H-0029:
Effect of Hydroxyurea on Fetal Hemoglobin Synthesis in Patients with Sickle Cell Anemia

* 79-C-0111:
The Treatment of Stage I and II Carcinoma of the Breast with Mastectomy and Axillary Dissection vs. Excisional Biopsy, Axillary Dissection, and Definitive Irradiation

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