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Determination of Glomerular Filtration Rate, Effective Renal Plasma Flow and Glomerular Capillary Wall Permselectivity
This study is currently recruiting participants.
Summary | Eligibility | Citations | Contacts
Summary
Number |
89-DK-0152 |
Sponsoring Institute |
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
Recruitment Detail |
Type: Participants currently recruited/enrolled |
Referral Letter Required |
No |
Population Exclusion(s) |
None |
Special Instructions |
Currently Not Provided |
Keywords |
Kidney Function Tests; |
Recruitment Keyword(s) |
None |
Condition(s) |
Kidney Disease |
Investigational Drug(s) |
None |
Investigational Device(s) |
None |
Intervention(s) |
None |
Supporting Site |
|
The study will select patients suffering from different types of kidney diseases. These patients will be selected based on the presence of significant amounts of protein in their urine (proteinuria).
Standard blood and urine tests are often unable to provide completely accurate information about the kidney. In order for researchers to have a more accurate idea of kidney function, they will use alternative tests. Test materials (para aminohippurate and inulin) will be injected into patients veins that provides information based on their filtration through the kidneys.
Eligibility
INCLUSION CRITERIA:
Ability to provide informed assent to all aspects of the study after full information is provided.
An indication to measure kidney function as accurately as possible in the context of an approved clinical protocol within the intramural programs of the National Institutes of Health:
- For minor subjects, a clinical indication will be required.
- For adult subjects, a clinical and/or research indication will be required.
EXCLUSION CRITERIA:
Pregnant females or nursing mothers will be excluded from all aspects of this study (at least until the infant is stable on a regimen of formula feeding).
Patients will not receive a test material if there is a history of allergy to that material.
Patients with a history of bronchial asthma or allergy to iodine-containing contrast material will not receive iothalamate.
Citations:
Contacts:
Principal Investigator |
Referral Contact |
For more information: |
| Howard A. Austin III, M.D. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) National Institutes of Health Building 10 Room 5-2543 10 Center Drive Bethesda, Maryland 20892 (301) 435-5055 howardaustin@mail.nih.gov |
Howard A. Austin III, M.D. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) National Institutes of Health Building 10 Room 5-2543 10 Center Drive Bethesda, Maryland 20892 (301) 435-5055 howardaustin@mail.nih.gov |
Patient Recruitment and Public Liaison Office Building 61 10 Cloister Court Bethesda, Maryland 20892-4754 Toll Free: 1-800-411-1222 TTY: 301-594-9774 (local),1-866-411-1010 (toll free) Fax: 301-480-9793 prpl@mail.cc.nih.gov |
Clinical Trials Number:
NCT00001978
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