Explore the NIHProtocol Details
A Training Protocol for the use of Botulinum Toxin in the Treatment of Neurological Disorders
This study is currently recruiting participants.
Summary | Eligibility | Citations | Contacts
Summary
Number |
85-N-0195 |
Sponsoring Institute |
National Institute of Neurological Disorders and Stroke (NINDS) |
Recruitment Detail |
Type: Participants currently recruited/enrolled |
Referral Letter Required |
Yes |
Population Exclusion(s) |
None |
Special Instructions |
The referring physician should send a letter and pertinent information to our research contact. Patients who may be suitable to participate in the protocol will have further evaluation in our Human Motor Control Clinic. |
Keywords |
Spasmodic Torticollis; |
Recruitment Keyword(s) |
Movement Disorders |
Condition(s) |
Chorea; |
Investigational Drug(s) |
None |
Investigational Device(s) |
None |
Intervention(s) |
None |
Supporting Site |
|
The study examines the effectiveness of botulinum toxin as treatment for a variety of movement disorders. The goals of the study are to refine the technique of treatment to provide the best results, to improve the understanding of how botulinum toxin works on movement disorders, and find other conditions that may be treatable with botulinum toxin.
In addition, researchers also plan to study the possible use of botulinum toxin F alone and in combination with botulinum toxin A in patients who do not respond to botulinum A toxin treatment.
Eligibility
INCLUSION CRITERIA:
Patients will be eligible for participation if they have a disorder that, in the judgment of the treating physician, might be amenable to treatment with BTX.
Applicable disorders include but are not limited to dystonia, hemifacial spasm, blepharospasm, tremor, spasmodic dysphonia, tics, vocal fold tremor, oral lingual dyskinesia, tardive dyskinesia, spasticity, and spasmodic dysphonia.
EXCLUSION CRITERIA:
Patients will be excluded form participation if:
1. They are pregnant or breastfeeding, for the duration of the condition.
2. They require treatment with an aminoglycoside antibiotic, until treatment is complete.
3. For laryngeal injections, they have a paradoxical vocal fold movement with intermittent stridor due to either gastroesophageal reflux or emotional disorders.
Citations:
Contacts:
Principal Investigator |
Referral Contact |
For more information: |
| Codrin I. Lungu, M.D. National Institute of Neurological Disorders and Stroke (NINDS) National Institutes of Health BG 10 RM 7D37 MSC 1428 10 CENTER DR BETHESDA MD 20892-1428 (301) 402-0976 lunguci@ninds.nih.gov |
Elaine P. Considine, R.N. National Institute of Neurological Disorders and Stroke (NINDS) National Institutes of Health Building 10 Room 7D36 10 Center Drive Bethesda, Maryland 20892 (301) 435-8518 considinee@ninds.nih.gov |
Patient Recruitment and Public Liaison Office Building 61 10 Cloister Court Bethesda, Maryland 20892-4754 Toll Free: 1-800-411-1222 TTY: 301-594-9774 (local),1-866-411-1010 (toll free) Fax: 301-480-9793 prpl@mail.cc.nih.gov |
Clinical Trials Number:
NCT00001208
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